PL374558A1 - Methods for the purification of levofloxacin - Google Patents

Methods for the purification of levofloxacin

Info

Publication number
PL374558A1
PL374558A1 PL02374558A PL37455802A PL374558A1 PL 374558 A1 PL374558 A1 PL 374558A1 PL 02374558 A PL02374558 A PL 02374558A PL 37455802 A PL37455802 A PL 37455802A PL 374558 A1 PL374558 A1 PL 374558A1
Authority
PL
Poland
Prior art keywords
levofloxacin
purification
methods
Prior art date
Application number
PL02374558A
Other languages
Polish (pl)
Inventor
Valerie Niddam-Hildesheim
Neomi Gershon
Eduard Schwartz
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/263,192 external-priority patent/US7629458B2/en
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of PL374558A1 publication Critical patent/PL374558A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
PL02374558A 2001-11-29 2002-11-27 Methods for the purification of levofloxacin PL374558A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33431601P 2001-11-29 2001-11-29
US35493902P 2002-02-11 2002-02-11
US26296502A 2002-10-03 2002-10-03
US10/263,192 US7629458B2 (en) 2001-10-03 2002-10-03 Preparation of levofloxacin and hemihydrate thereof

Publications (1)

Publication Number Publication Date
PL374558A1 true PL374558A1 (en) 2005-10-31

Family

ID=31892240

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02374558A PL374558A1 (en) 2001-11-29 2002-11-27 Methods for the purification of levofloxacin

Country Status (13)

Country Link
EP (1) EP1460997A4 (en)
JP (3) JP2005527484A (en)
CN (1) CN1596256A (en)
AU (1) AU2002365416A1 (en)
CA (1) CA2466860A1 (en)
HR (1) HRP20040546A2 (en)
HU (1) HUP0500285A3 (en)
IL (1) IL162172A0 (en)
IS (1) IS7288A (en)
MX (1) MXPA04005196A (en)
NO (1) NO20042731L (en)
PL (1) PL374558A1 (en)
WO (1) WO2003045329A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002341991A1 (en) 2001-10-03 2003-04-14 Teva Pharmaceutical Industries Ltd. Methods for the purification of levofloxacin
WO2004055025A1 (en) * 2002-12-16 2004-07-01 Ranbaxy Laboratories Limited Pure levofloxacin hemihydrate and processes for preparation thereof
KR100704641B1 (en) * 2004-07-21 2007-04-06 주식회사유한양행 Methods for the preparation of levofloxacin having a high purity
JP2006273718A (en) * 2005-03-28 2006-10-12 Shiono Chemical Co Ltd Method for producing levofloxacin-1/2 hydrate
CN1321121C (en) * 2005-04-21 2007-06-13 浙江医药股份有限公司新昌制药厂 Post processing method for preparing levo-ofloxacin
US7964723B2 (en) * 2008-08-02 2011-06-21 Apeloa-Kangyu And practical process for exclusively producing (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3,de][1,4]benzoxazine-6-carboxylic acid hemihydrate
CN102070650B (en) * 2011-01-28 2012-06-27 山东省药品检验所 Preparation method for levofloxacin-N-oxide
US20120251685A1 (en) * 2011-04-04 2012-10-04 Martek Biosciences Corporation Oil-in-Water Emulsions Comprising a Polyunsaturated Fatty Acid and Methods of Making the Same
CN105823851A (en) * 2015-12-15 2016-08-03 浙江海洋学院 Detection method for ofloxacin enantiomer in seawater
CN108218892A (en) * 2018-03-16 2018-06-29 乐山职业技术学院 A kind of purification process of lavo-ofloxacin
CN114507242B (en) * 2022-01-26 2023-05-19 上虞京新药业有限公司 Preparation method of levofloxacin with high optical purity

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO166131C (en) * 1985-06-20 1991-06-05 Daiichi Seiyaku Co ANALOGUE PROCEDURE FOR THE PREPARATION OF S (-) - PYRIDOBENZOKSAZINE COMPOUNDS.
US5237060A (en) * 1985-12-10 1993-08-17 Bayer Aktiengesellschaft Process of preparing enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids
TW208013B (en) * 1990-03-01 1993-06-21 Daiichi Co Ltd
JPH07501835A (en) * 1992-10-07 1995-02-23 デリバドス・デル・エチロ・ソシエダッド・アノニマ Process for producing benzoxazine used in the synthesis of ofloxazine, levofloxazine and derivatives
KR0125115B1 (en) * 1994-03-22 1997-12-05 김은영 Process for preparing piperazinyl quinolone derivatives
KR100309871B1 (en) * 1999-02-24 2001-10-29 윤종용 Process for Preparing (-)Pyridobenzoxazine Carboxylic Acid Derivatives
AU2002341991A1 (en) * 2001-10-03 2003-04-14 Teva Pharmaceutical Industries Ltd. Methods for the purification of levofloxacin

Also Published As

Publication number Publication date
CA2466860A1 (en) 2003-06-05
WO2003045329A2 (en) 2003-06-05
WO2003045329A3 (en) 2004-02-19
EP1460997A2 (en) 2004-09-29
HUP0500285A3 (en) 2009-03-30
IL162172A0 (en) 2005-11-20
MXPA04005196A (en) 2005-11-23
HUP0500285A2 (en) 2005-06-28
JP2008007517A (en) 2008-01-17
CN1596256A (en) 2005-03-16
JP2006219496A (en) 2006-08-24
AU2002365416A1 (en) 2003-06-10
JP2005527484A (en) 2005-09-15
IS7288A (en) 2004-06-21
HRP20040546A2 (en) 2004-10-31
EP1460997A4 (en) 2005-06-15
NO20042731L (en) 2004-06-29

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Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)