PL368940A1 - Podstawione imidazolidyny, sposób ich wytwarzania, ich zastosowanie jako środków leczniczych albo diagnostycznych oraz środek leczniczy zawierający te związki - Google Patents

Podstawione imidazolidyny, sposób ich wytwarzania, ich zastosowanie jako środków leczniczych albo diagnostycznych oraz środek leczniczy zawierający te związki

Info

Publication number
PL368940A1
PL368940A1 PL02368940A PL36894002A PL368940A1 PL 368940 A1 PL368940 A1 PL 368940A1 PL 02368940 A PL02368940 A PL 02368940A PL 36894002 A PL36894002 A PL 36894002A PL 368940 A1 PL368940 A1 PL 368940A1
Authority
PL
Poland
Prior art keywords
drug
substituted imidazolidines
diagnosis
production
imidazolidines
Prior art date
Application number
PL02368940A
Other languages
English (en)
Inventor
Uwe Heinelt
Hans-Jochen Lang
Armin Hofmeister
Klaus Wirth
Original Assignee
Aventis Pharma Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland Gmbh filed Critical Aventis Pharma Deutschland Gmbh
Publication of PL368940A1 publication Critical patent/PL368940A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL02368940A 2001-12-21 2002-12-09 Podstawione imidazolidyny, sposób ich wytwarzania, ich zastosowanie jako środków leczniczych albo diagnostycznych oraz środek leczniczy zawierający te związki PL368940A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10163239A DE10163239A1 (de) 2001-12-21 2001-12-21 Substituierte Imidazolidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
PL368940A1 true PL368940A1 (pl) 2005-04-04

Family

ID=7710363

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02368940A PL368940A1 (pl) 2001-12-21 2002-12-09 Podstawione imidazolidyny, sposób ich wytwarzania, ich zastosowanie jako środków leczniczych albo diagnostycznych oraz środek leczniczy zawierający te związki

Country Status (27)

Country Link
EP (1) EP1461034B1 (pl)
JP (1) JP4571803B2 (pl)
KR (1) KR100959031B1 (pl)
CN (1) CN100339079C (pl)
AR (1) AR037932A1 (pl)
AT (1) ATE345797T1 (pl)
AU (1) AU2002361990B2 (pl)
BR (1) BR0215154A (pl)
CA (1) CA2470856A1 (pl)
CO (1) CO5590925A2 (pl)
DE (2) DE10163239A1 (pl)
DK (1) DK1461034T3 (pl)
ES (1) ES2275945T3 (pl)
HR (1) HRP20040573A2 (pl)
HU (1) HUP0600836A2 (pl)
IL (2) IL162562A0 (pl)
MA (1) MA27149A1 (pl)
MX (1) MXPA04005388A (pl)
MY (1) MY134344A (pl)
NO (1) NO20043009L (pl)
PE (1) PE20030741A1 (pl)
PL (1) PL368940A1 (pl)
RS (1) RS53204A (pl)
RU (1) RU2004122415A (pl)
TW (1) TW200305408A (pl)
WO (1) WO2003053434A1 (pl)
ZA (1) ZA200404149B (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10323701A1 (de) 2003-05-22 2004-12-23 Aventis Pharma Deutschland Gmbh Verfahren zur Synthese heterocyclischer Verbindungen
EP1640361B9 (en) 2003-06-30 2015-11-04 Sumitomo Chemical Company, Limited Asymmetric urea compounds and process for producing asymmetric compounds by asymmetric conjugate addition reaction using the same as catalyst
DE10341240A1 (de) * 2003-09-08 2005-04-07 Aventis Pharma Deutschland Gmbh Substituierte Thienoimidazole, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
WO2016013657A1 (ja) 2014-07-25 2016-01-28 大正製薬株式会社 ヘテロアリールで置換されたフェニルテトラヒドロイソキノリン化合物

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3202660A (en) * 1961-10-09 1965-08-24 Boehringer Sohn Ingelheim Process for the preparation of 3-arylamino-1, 3-diazacycloalkenes
US3236857A (en) * 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
EP0070084A3 (en) * 1981-04-24 1983-02-16 Beecham Group Plc Imidazoline derivatives
DE3712385A1 (de) * 1987-04-11 1988-10-27 Boehringer Ingelheim Kg 2-(phenylimino)imidazolidine
GB9313330D0 (en) * 1993-06-28 1993-08-11 Fujisawa Pharmaceutical Co New compound and its preparation
EP0639573A1 (de) * 1993-08-03 1995-02-22 Hoechst Aktiengesellschaft Benzokondensierte 5-Ringheterocyclen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, ihre Verwendung als Diagnostikum, sowie sie enthaltendes Medikament
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
KR100257129B1 (ko) * 1993-09-11 2000-05-15 성재갑 신규 세팔로스포린계 항생제 및 이의 제조방법
US5552415A (en) * 1993-12-21 1996-09-03 Eli Lilly And Company Method of inhibiting Alzheimer's Disease
DE19548812A1 (de) * 1995-12-27 1997-07-03 Hoechst Ag Verwendung von Inhibitoren des zellulären Na·+·/H·+·-Exchangers (NHE) zur Herstellung eines Medikaments zur Atemstimulation
DE19633966A1 (de) * 1996-08-22 1998-02-26 Hoechst Ag Phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
ATE244717T1 (de) * 1997-03-14 2003-07-15 Vertex Pharma Inhibitoren des impdh-enzyms
DE19945302A1 (de) * 1999-09-22 2001-03-29 Merck Patent Gmbh Biphenylderivate als NHE-3-Inhibitoren
DE19950898A1 (de) * 1999-10-22 2001-04-26 Aventis Pharma Gmbh Heterocyclisch substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19960204A1 (de) * 1999-12-14 2001-06-28 Aventis Pharma Gmbh Substituierte Norlbornylamino-Derivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE10015248A1 (de) * 2000-03-28 2001-10-04 Merck Patent Gmbh Bisamidino-Verbindungen als NHE-3 Inhibitoren
DE10019062A1 (de) * 2000-04-18 2001-10-25 Merck Patent Gmbh 2-Guanidino-4-aryl-chinazoline als NHE-3 Inhibitoren
DE10060292A1 (de) * 2000-12-05 2002-06-20 Aventis Pharma Gmbh Verwendung substituierter Benzimidazole zur Herstellung eines Medikaments zur Behandlung von Krankheiten, welche durch Inhibierung des Na+/H+-Austauschers beeinflusst werden können und sie enthaltendes Medikament

Also Published As

Publication number Publication date
CN1606440A (zh) 2005-04-13
JP2005516947A (ja) 2005-06-09
NO20043009L (no) 2004-07-15
PE20030741A1 (es) 2003-09-29
EP1461034A1 (de) 2004-09-29
CO5590925A2 (es) 2005-12-30
MY134344A (en) 2007-12-31
IL162562A0 (en) 2005-11-20
ATE345797T1 (de) 2006-12-15
MXPA04005388A (es) 2004-10-11
JP4571803B2 (ja) 2010-10-27
CN100339079C (zh) 2007-09-26
RU2004122415A (ru) 2005-03-27
MA27149A1 (fr) 2005-01-03
RS53204A (sr) 2006-10-27
DK1461034T3 (da) 2007-03-26
CA2470856A1 (en) 2003-07-03
BR0215154A (pt) 2004-10-19
TW200305408A (en) 2003-11-01
IL162562A (en) 2009-12-24
EP1461034B1 (de) 2006-11-22
WO2003053434A1 (de) 2003-07-03
AU2002361990B2 (en) 2008-10-09
DE10163239A1 (de) 2003-07-10
DE50208809D1 (de) 2007-01-04
ZA200404149B (en) 2006-05-31
AR037932A1 (es) 2004-12-22
KR20040068322A (ko) 2004-07-30
HRP20040573A2 (en) 2004-10-31
ES2275945T3 (es) 2007-06-16
KR100959031B1 (ko) 2010-05-20
AU2002361990A1 (en) 2003-07-09
HUP0600836A2 (en) 2008-04-28

Similar Documents

Publication Publication Date Title
IL160440A (en) Dihydropteridinones, method for producing the same and the use thereof as medicaments
MXPA03005018A (es) Derivados de difenilazetidinonas, metodo para su produccion farmacos que contienen estos compuestos, y su uso.
MXPA03005019A (es) Derivados de difenilazetidinonas, metodo para su produccion farmacos que contienen estos compuestos y su uso.
AU2003257465A1 (en) Substituted diaryl heterocycles, method for the production and use thereof as medicaments
MXPA03001483A (es) Heterociclos biciclicos medicamentos que contienen estos compuestos, su empleo y procedimientos para su preparacion.
MXPA03000873A (es) Derivados de quinazolina, medicamentos que contienen estos compuestos, su uso y metodos para la produccion de los mismos.
IL162669A0 (en) Antichlinergic agents, method for producing the same and use thereof as medicaments
HUP0402264A3 (en) Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines process for preparing them, pharmaceutical compositions containing them and use thereof
PL376399A1 (pl) Nowe związki pirydopirymidynowe, proces ich wytwarzania i zawierające je mieszanki farmaceutyczne
MXPA03001510A (es) Heterociclos biciclicos, medicamentos que contiene estos compuestos, su empleo y procedimientos para su preparacion.
IL162316A0 (en) Substituted 4-phenyltetrahydroisoquinolines, method for the production thereof, the use thereof as medicaments, in addition t
IL161893A0 (en) 5-Phenylpyrimidines, agents comprising the same, method for production and use thereof
IL165213A0 (en) Pentafluorosulfanyl-benzoylguanidine, method for the production thereof and its utilizationmedicament or diagnostic agent and medicament containing same
IL150228A0 (en) Substituted norbornylamino derivatives, method for the production thereof, use thereof as medicament or a diagnostic reagent and medicaments containing said compounds
HRP20041153A2 (en) Substituted thiophenes, method for the production thereof, their use as a medicament or diagnostic reagent, and a medicament containing the same
IL162562A0 (en) Substituted imidazolidines, method for the production thereof, use thereof as a drug or for diagnosis, and drug containing substituted imidazolid
ZA200601001B (en) Substituted thienoimidazoles, method for production and use thereof as medicament or diagnostic and medicament comprising the same
AU2002348998A1 (en) N-methyl-homocystines, use thereof and method for the production thereof
MXPA03007550A (es) Derivados coloporosidos, proceso para su preparacion y su uso.
PL370271A1 (pl) Dihydrotiafenantrenokarbonyloguanidyny, sposób ich wytwarzania, ich zastosowanie jako środka leczniczego lub diagnostycznego
SI1513834T1 (sl) Substituirani tiofeni, postopek za njihovo pripravo, njihova uporaba kot zdravilo ali kot diagnostik kot tudi zdravilo, ki jih vsebuje
ZA200205696B (en) Substituted benzoylguanidines, method for their production, their use as a medicament or diagnostic agent and a medicament containing the same.
MXPA03008636A (es) Derivados de isoquinuclidina, metodo para fabricar los mismos y agentes terapeuticos que contienen estos compuestos.
SI1509498T1 (sl) Pentafluorosulfanil-benzoilgvanidini, postopek za njihovo pripravo, njihova uporaba kot zdravilo ali diagnosticno sredstvo in zdravilo, ki jih vsebuje
SI1456212T1 (sl) Derivati 6-aminomorfinana, postopek za njihovo izdelavo in njihova uporaba

Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)