PL3670522T3 - Krystaliczna postać chlorku rybozydu nikotynamidu - Google Patents

Krystaliczna postać chlorku rybozydu nikotynamidu

Info

Publication number
PL3670522T3
PL3670522T3 PL20153772T PL20153772T PL3670522T3 PL 3670522 T3 PL3670522 T3 PL 3670522T3 PL 20153772 T PL20153772 T PL 20153772T PL 20153772 T PL20153772 T PL 20153772T PL 3670522 T3 PL3670522 T3 PL 3670522T3
Authority
PL
Poland
Prior art keywords
crystalline form
nicotinamide riboside
riboside chloride
chloride
nicotinamide
Prior art date
Application number
PL20153772T
Other languages
English (en)
Inventor
Erik C. Carlson
Michael C. Standen
Westin M. Morrill
Original Assignee
W.R. Grace & Co. - Conn.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55163976&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3670522(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by W.R. Grace & Co. - Conn. filed Critical W.R. Grace & Co. - Conn.
Publication of PL3670522T3 publication Critical patent/PL3670522T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/048—Pyridine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
PL20153772T 2014-07-24 2015-07-24 Krystaliczna postać chlorku rybozydu nikotynamidu PL3670522T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462028702P 2014-07-24 2014-07-24
EP20153772.7A EP3670522B1 (en) 2014-07-24 2015-07-24 Crystalline form of nicotinamide riboside chloride
EP15825253.6A EP3174891B1 (en) 2014-07-24 2015-07-24 Crystalline form of nicotinamide riboside
PCT/US2015/041956 WO2016014927A2 (en) 2014-07-24 2015-07-24 Crystalline form of nicotinamide riboside

Publications (1)

Publication Number Publication Date
PL3670522T3 true PL3670522T3 (pl) 2022-02-21

Family

ID=55163976

Family Applications (2)

Application Number Title Priority Date Filing Date
PL20153772T PL3670522T3 (pl) 2014-07-24 2015-07-24 Krystaliczna postać chlorku rybozydu nikotynamidu
PL15825253T PL3174891T3 (pl) 2014-07-24 2015-07-24 Krystaliczna postać rybozydu nikotynamidu

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL15825253T PL3174891T3 (pl) 2014-07-24 2015-07-24 Krystaliczna postać rybozydu nikotynamidu

Country Status (7)

Country Link
US (2) US10323058B2 (pl)
EP (2) EP3670522B1 (pl)
CN (1) CN106715454B (pl)
CA (1) CA2956163C (pl)
ES (2) ES2776395T3 (pl)
PL (2) PL3670522T3 (pl)
WO (1) WO2016014927A2 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3268379B1 (en) * 2015-03-09 2023-11-01 W.R. Grace & CO. - CONN. Crystalline form of nicotinamide riboside
EA035664B1 (ru) 2015-08-05 2020-07-23 МЕТРО ИНТЕРНЭШНЛ БАЙОТЕК, ЭлЭлСи Производные никотинамидмононуклеотида и их применение для лечения заболевания или расстройства, связанного с биосинтезом над+
GB2542881B (en) 2015-10-02 2020-01-01 Carr Andrew Crystal forms of ß-nicotinamide mononucleotide
CA3017254C (en) 2016-03-16 2023-08-22 ChromaDex Inc. B-vitamin and amino acid conjugates of nicotinoyl ribosides and reduced nicotinoyl ribosides, derivatives thereof, and methods of preparation thereof
WO2017218580A1 (en) 2016-06-14 2017-12-21 Rejuvenation Therapeutics Corporation Synthetic methods for the preparation of nicotinamide riboside and related compounds
CA3045876A1 (en) 2016-11-11 2018-05-17 The Queen's University Of Belfast Scalable syntheses of nicotinoyl ribosides and reduced nic otinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof
AU2017367092B2 (en) 2016-11-29 2022-11-03 University Of Iowa Research Foundation Use of NAD precursors for improving maternal health and/or offspring health
US11071747B2 (en) 2016-11-29 2021-07-27 University Of Iowa Research Foundation Use of NAD precursors for breast enhancement
SG11201912267SA (en) 2017-06-19 2020-01-30 Gangadhara Ganapati Nicotinamide riboside derivatives and their uses
CN112020363A (zh) * 2017-12-22 2020-12-01 益力舒健康公司 烟酰胺核苷氯化物的结晶形式
AU2019214858B2 (en) 2018-01-30 2023-02-02 Metro International Biotech, Llc Nicotinamide riboside analogs, pharmaceutical compositions, and uses thereof
EP3794007A1 (en) * 2018-05-18 2021-03-24 Roche Diagnostics GmbH (thio)nicotinamide ribofuranoside salts and compositions, methods of making, and uses thereof
CN108774278A (zh) * 2018-09-10 2018-11-09 张洪喜 一种制备尼克酰胺核苷盐的方法
CA3122527A1 (en) 2018-12-10 2020-06-18 ChromaDex Inc. Crystalline forms of nicotinoyl ribosides and derivatives thereof, and methods of preparation thereof
WO2020131578A2 (en) 2018-12-17 2020-06-25 Mitopower Llc Nicotinyl riboside compounds and their uses
MX2021010043A (es) * 2019-02-21 2022-07-19 Chromadex Inc Uso de nicotinamida ribósido, ácido nicotinico ribósido, compuestos de nicotinil ribósido reducido y derivados de compuestos de nicotinil ribósido en formulaciones.
US10618927B1 (en) 2019-03-22 2020-04-14 Metro International Biotech, Llc Compositions and methods for modulation of nicotinamide adenine dinucleotide
US11939348B2 (en) 2019-03-22 2024-03-26 Metro International Biotech, Llc Compositions comprising a phosphorus derivative of nicotinamide riboside and methods for modulation of nicotinamide adenine dinucleotide
KR20220039747A (ko) 2019-07-19 2022-03-29 바이오신스 아게 니코틴아미드 리보푸라노사이드 염의 제조 방법, 니코틴아미드 리보푸라노사이드 염, 및 이의 용도
CN111808156A (zh) * 2020-07-15 2020-10-23 许昌远志生物科技有限公司 一种β-烟酰胺核糖氯化物的晶型1A、晶型1B及其制备方法
CN117545488A (zh) 2021-05-27 2024-02-09 麦德龙国际生物科技有限责任公司 烟酸单核苷酸及其酯的结晶固体以及其制作和使用方法

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1190080A (en) 1966-08-08 1970-04-29 Kyowa Hakko Kogyo Company Ltd Process for producing Nicotinamide Adenine Dinucleotide
US3728111A (en) 1971-09-21 1973-04-17 Asea Ab Method of manufacturing billets from powder
US6348589B1 (en) 1997-02-06 2002-02-19 Inspire Pharmaceuticals, Inc. Certain dinucleotides and their use as modulators of mucociliary clearance and ciliary beat frequency
GB9712370D0 (en) 1997-06-14 1997-08-13 Aepact Ltd Therapeutic systems
AU2002232660A1 (en) 2000-12-15 2002-06-24 Pharmasset Ltd. Antiviral agents for treatment of flaviviridae infections
US7179791B2 (en) 2001-01-11 2007-02-20 Duke University Inhibiting GS-FDH to modulate NO bioactivity
US7977049B2 (en) * 2002-08-09 2011-07-12 President And Fellows Of Harvard College Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms
US20050020587A1 (en) * 2003-07-25 2005-01-27 Pfizer Inc Nicotinamide derivatives useful as PDE4 inhibitors
US8017634B2 (en) 2003-12-29 2011-09-13 President And Fellows Of Harvard College Compositions for treating obesity and insulin resistance disorders
US8114626B2 (en) 2004-02-10 2012-02-14 Trustees Of Dartmouth College Yeast strain and method for using the same to produce nicotinamide riboside
CA2555675A1 (en) 2004-02-10 2005-08-25 Trustees Of Dartmouth College Nicotinamide riboside kinase compositions and methods for using the same
WO2006001982A2 (en) 2004-06-04 2006-01-05 Washington University Methods and compositions for treating neuropathies
NZ561613A (en) 2005-02-18 2010-12-24 Astrazeneca Ab Antibacterial piperidine derivatives
WO2006105440A2 (en) 2005-03-30 2006-10-05 Sirtris Pharmaceuticals, Inc. Nicotinamide riboside and analogues thereof
US20070149466A1 (en) 2005-07-07 2007-06-28 Michael Milburn Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders
WO2007061798A2 (en) 2005-11-18 2007-05-31 Cornell Research Foundation, Inc. Nicotinoyl riboside compositions and methods of use
AU2006339607A1 (en) 2005-12-02 2007-09-13 Sirtris Pharmaceuticals, Inc. Modulators of Cdc2-like kinases (Clks) and methods of use thereof
WO2007136744A1 (en) 2006-05-19 2007-11-29 The Johns Hopkins University Crystal structure of a substrate complex of nampt/pbef/visfatin
EP2129660A2 (en) * 2006-12-19 2009-12-09 Pfizer Products Inc. Nicotinamide derivatives as inhibitors of h-pgds and their use for treating prostaglandin d2 mediated diseases
CA2676609A1 (en) 2007-01-26 2008-07-31 Washington University Methods and compositions for treating neuropathies
US20110306597A1 (en) * 2008-06-18 2011-12-15 James Michael Crawforth Nicotinamide Derivatives
WO2010002586A2 (en) 2008-06-30 2010-01-07 Elc Management Llc Topical compositions comprising isonicotinamide
WO2010017374A1 (en) 2008-08-06 2010-02-11 Sicor Inc. Process for preparing azacytidine intermediate
WO2011005289A2 (en) 2009-06-23 2011-01-13 President And Fellows Of Harvard College Methods and kits for measuring enzyme activity
UA108856C2 (uk) 2009-07-24 2015-06-25 Пунікалін (punicalin) та пунікалагін (punicalagin) для захисту здоров'я головного мозку при нейродегенеративних розладах
US8507251B2 (en) 2009-09-28 2013-08-13 Robert J. Greenstein Medium and method for culturing Mycobacterium avium subspecies paratuberculosis
WO2011081942A1 (en) * 2009-12-14 2011-07-07 Cornell University Activation and activators of sirt5
EP2464249B1 (de) 2010-03-29 2013-03-13 Johannes Huber Konzentrationssteigerndes getränk
US8481711B2 (en) 2010-07-06 2013-07-09 Hidenori Kamanishi Neurite outgrowth agent
US20140065099A1 (en) 2011-02-15 2014-03-06 Ecole Polytechnique Federale De Lausanne (Epfl) Methods of Treating Mitochondrial Dysfunction
US20120107888A1 (en) 2011-02-17 2012-05-03 Qteros, Inc. Modulation of fermentation products through vitamin supplementation
US20120328526A1 (en) 2011-06-27 2012-12-27 University Of Maryland, Baltimore Modulation of Nad+ Activity in Neuropathophysiological Conditions and Uses Thereof
EP3345901A3 (en) 2011-06-29 2018-09-12 President and Fellows of Harvard College Small molecules as antiaging agents
WO2013002880A1 (en) 2011-06-29 2013-01-03 The General Hospital Corporation Compositions and methods for enhancing bioenergetic status in female germ cells
EP2869717B8 (en) 2012-07-09 2018-07-25 NoGlo, Inc. Prevention of alcohol reaction with dietary supplements
US20140256760A1 (en) 2012-07-09 2014-09-11 Noglo Llc Reduction or prevention of alcohol reaction with dietary supplements
US9861651B2 (en) 2012-07-16 2018-01-09 Cornell University Use of nicotinamide riboside to treat hearing loss
WO2014059029A1 (en) 2012-10-09 2014-04-17 President And Fellows Of Harvard College Treatment of age-related and mitochondrial diseases by inhibition of hif-1 alpha function
WO2014111906A1 (en) 2013-01-21 2014-07-24 Ecole Polytechnique Federale De Lausanne (Epfl) Bioluminescence imaging of small biomolecules
CN105228627B (zh) 2013-03-15 2018-07-13 纽斯尔特科学公司 亮氨酸和烟酸降低脂质水平
GB201313465D0 (en) * 2013-07-29 2013-09-11 Queens University Of The Belfast Methods of preparing nicotinamide riboside and derivatives thereof
CN105682748B (zh) 2013-10-24 2021-03-12 宝洁公司 亮肤化妆品组合物及方法
WO2015064988A1 (ko) 2013-10-29 2015-05-07 한림대학교 산학협력단 니코틴아마이드 라이보사이드를 유효성분으로 포함하는 패혈증 치료 또는 예방용 약제학적 조성물
KR20220098049A (ko) 2013-10-30 2022-07-08 크로마덱스 아이엔씨. 피부 질환 치료에서의 국소적 사용을 위한 니코틴아미드 리보사이드 조성물
CA2929666C (en) 2013-11-12 2023-08-01 Ortho-Nutra, Llc Theacrine-based supplement and method of use thereof
WO2015099842A1 (en) 2013-12-23 2015-07-02 Abbott Laboratories Hot beverage fortifier
AU2015229055B2 (en) 2014-03-13 2019-09-12 Salk Institute For Biological Studies Analogs of fexaramine and methods of making and using
CA2942403A1 (en) 2014-03-13 2015-09-17 Salk Institute For Biological Studies Fxr agonists and methods for making and using
US20150297508A1 (en) 2014-04-21 2015-10-22 William Andriette Topical Formulation to Enhance Genital Sensation and Function
US10316054B2 (en) * 2014-06-02 2019-06-11 Glaxosmithkline Intellectual Property (No. 2) Limited Preparation and use of crystalline beta-D-nicotinamide riboside
RU2016149767A (ru) 2014-06-06 2018-07-16 Глэксосмитклайн Интеллекчуал Проперти (Но.2) Лимитед Аналоги никотинамидрибозида и фармацевтические композиции и их применение
EP3169333A4 (en) 2014-07-17 2018-03-07 The Scripps Research Institute Methods and compositions for enhancing cancer therapy
EP3268379B1 (en) * 2015-03-09 2023-11-01 W.R. Grace & CO. - CONN. Crystalline form of nicotinamide riboside

Also Published As

Publication number Publication date
US20180086783A1 (en) 2018-03-29
US10233207B2 (en) 2019-03-19
WO2016014927A2 (en) 2016-01-28
EP3174891A2 (en) 2017-06-07
PL3174891T3 (pl) 2020-08-10
ES2908332T3 (es) 2022-04-28
ES2776395T3 (es) 2020-07-30
US10323058B2 (en) 2019-06-18
CN106715454B (zh) 2020-06-16
CN106715454A (zh) 2017-05-24
EP3670522B1 (en) 2022-01-19
WO2016014927A3 (en) 2016-09-15
US20170210774A1 (en) 2017-07-27
EP3174891A4 (en) 2018-05-30
CA2956163A1 (en) 2016-01-28
EP3174891B1 (en) 2020-01-29
EP3670522A1 (en) 2020-06-24
CA2956163C (en) 2023-01-10

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