PL3655017T3 - Kompozycja farmaceutyczna - Google Patents

Kompozycja farmaceutyczna

Info

Publication number
PL3655017T3
PL3655017T3 PL18759254.8T PL18759254T PL3655017T3 PL 3655017 T3 PL3655017 T3 PL 3655017T3 PL 18759254 T PL18759254 T PL 18759254T PL 3655017 T3 PL3655017 T3 PL 3655017T3
Authority
PL
Poland
Prior art keywords
pharmaceutical composition
pharmaceutical
composition
Prior art date
Application number
PL18759254.8T
Other languages
English (en)
Inventor
Christophe ROBERGE
Anthony RECH
Jean-Manuel CROS
Myriam ABBASSI
Adolfo LÓPEZ-NORIEGA
Lea PEBREL
Audrey Petit
Juliette SERINDOUX
Original Assignee
Medincell S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medincell S.A. filed Critical Medincell S.A.
Publication of PL3655017T3 publication Critical patent/PL3655017T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0029—Parenteral nutrition; Parenteral nutrition compositions as drug carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66—Polyesters containing oxygen in the form of ether groups
    • C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00—Applications
    • C08L2203/02—Applications for biomedical use
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/02—Polymer mixtures characterised by other features containing two or more polymers of the same C08L -group
    • C08L2205/025—Polymer mixtures characterised by other features containing two or more polymers of the same C08L -group containing two or more polymers of the same hierarchy C08L, and differing only in parameters such as density, comonomer content, molecular weight, structure
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/03—Polymer mixtures characterised by other features containing three or more polymers in a blend

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL18759254.8T 2017-07-17 2018-07-17 Kompozycja farmaceutyczna PL3655017T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762533370P 2017-07-17 2017-07-17
PCT/EP2018/069439 WO2019016233A1 (en) 2017-07-17 2018-07-17 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
PL3655017T3 true PL3655017T3 (pl) 2025-06-09

Family

ID=63047314

Family Applications (2)

Application Number Title Priority Date Filing Date
PL18759254.8T PL3655017T3 (pl) 2017-07-17 2018-07-17 Kompozycja farmaceutyczna
PL18746859.0T PL3655038T3 (pl) 2017-07-17 2018-07-17 Kompozycja farmaceutyczna

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL18746859.0T PL3655038T3 (pl) 2017-07-17 2018-07-17 Kompozycja farmaceutyczna

Country Status (25)

Country Link
US (3) US11612563B2 (pl)
EP (4) EP3655038B1 (pl)
JP (3) JP7205019B6 (pl)
KR (1) KR102745079B1 (pl)
CN (1) CN111107840A (pl)
AR (3) AR113097A1 (pl)
AU (1) AU2018304881B2 (pl)
BR (1) BR112020001031A2 (pl)
CA (1) CA3069787A1 (pl)
DK (2) DK3655017T3 (pl)
EA (1) EA202090161A1 (pl)
ES (2) ES3015765T3 (pl)
FI (2) FI3655038T3 (pl)
HR (2) HRP20250339T1 (pl)
HU (2) HUE070940T2 (pl)
IL (1) IL271986B2 (pl)
LT (2) LT3655038T (pl)
MX (1) MX2020000618A (pl)
PL (2) PL3655017T3 (pl)
PT (2) PT3655017T (pl)
RS (1) RS66643B1 (pl)
SI (2) SI3655038T1 (pl)
SM (1) SMT202500130T1 (pl)
TW (3) TWI795422B (pl)
WO (3) WO2019016233A1 (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI3655038T3 (fi) * 2017-07-17 2025-02-11 Medincell S A Farmaseuttinen koostumus
GB201900258D0 (en) 2019-01-08 2019-02-27 Medincell Pharmaceutical composition
US11680107B2 (en) 2019-03-22 2023-06-20 Taipei Medical University Hydrogel composition for drug delivery and uses thereof
MX2022003051A (es) * 2019-09-13 2022-06-14 Medincell S A Formulaciones para la administracion de farmacos.
EP4100002A4 (en) * 2020-01-10 2024-09-25 Equilibre Biopharmaceuticals BV TREATMENT OF NEUROLOGICAL DISORDERS WITH AVERMECTINS
GB202010340D0 (en) * 2020-07-06 2020-08-19 Medincell Pharmaceutical composition
EP4014963A1 (en) * 2020-12-16 2022-06-22 Medincell Pharmaceutical composition
CN116847827A (zh) * 2020-12-16 2023-10-03 美蒂森股份公司 用于预防性治疗SARS-CoV-2病毒（COVID-19）的方法和组合物
GB202104224D0 (en) * 2021-03-25 2021-05-12 Medincell Pharmaceutical composition
WO2022229402A1 (en) * 2021-04-30 2022-11-03 Medincell Sa New formulation
US20250009647A1 (en) 2021-08-05 2025-01-09 Medincell S.A. Pharmaceutical composition
CN120569188A (zh) * 2023-01-10 2025-08-29 美蒂森股份公司 奥氮平组合物和使用方法
WO2025104289A1 (en) 2023-11-17 2025-05-22 Medincell S.A. Antineoplastic combinations
WO2025224317A1 (en) * 2024-04-25 2025-10-30 Medincell S.A. A method for targeting pharmaceutically active principle in total knee replacement

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL113359A (en) 1995-04-13 1999-06-20 Univ Ben Gurion Polysaccharide drug delivery matrix and slow release pharmaceutical preparation containing it
FR2741628B1 (fr) 1995-11-29 1998-02-06 Centre Nat Rech Scient Nouveaux hydrogels a base de copolymeres trisequences et leur application notamment a la liberation progressive de principes actifs
CA2299393A1 (en) 1997-08-08 1999-02-18 Sung Wan Kim Injectable biodegradable block copolymer gels for use in drug delivery
US20020164374A1 (en) * 1997-10-29 2002-11-07 John Jackson Polymeric systems for drug delivery and uses thereof
US6541033B1 (en) 1998-06-30 2003-04-01 Amgen Inc. Thermosensitive biodegradable hydrogels for sustained delivery of leptin
KR100416242B1 (ko) 1999-12-22 2004-01-31 주식회사 삼양사 약물전달체용 생분해성 블록 공중합체의 액체 조성물 및이의 제조방법
US7018645B1 (en) * 2000-04-27 2006-03-28 Macromed, Inc. Mixtures of various triblock polyester polyethylene glycol copolymers having improved gel properties
US20020192286A1 (en) * 2001-03-27 2002-12-19 Macromed, Incorporated Biodegradable triblock copolymers as solubilizing agents for drugs and method of use thereof
IL151288A0 (en) 2001-08-27 2003-04-10 Yissum Res Dev Co Multi-component reverse thermo-sensitive polymeric systems
US6592899B2 (en) 2001-10-03 2003-07-15 Macromed Incorporated PLA/PLGA oligomers combined with block copolymers for enhancing solubility of a drug in water
US20030228366A1 (en) 2002-06-11 2003-12-11 Chung Shih Reconstitutable compositions of biodegradable block copolymers
US7649023B2 (en) 2002-06-11 2010-01-19 Novartis Ag Biodegradable block copolymeric compositions for drug delivery
US20060034889A1 (en) * 2004-08-16 2006-02-16 Macromed, Inc. Biodegradable diblock copolymers having reverse thermal gelation properties and methods of use thereof
US20060046961A1 (en) 2004-09-02 2006-03-02 Mckay William F Controlled and directed local delivery of anti-inflammatory compositions
WO2007019439A2 (en) 2005-08-04 2007-02-15 Angiotech International Ag Block copolymer compositions and uses thereof
WO2007101443A1 (en) * 2006-03-09 2007-09-13 Coloplast A/S Degradable hydrophilic block copolymers with improved biocompatibility for soft tissue regeneration
DK2644192T3 (en) 2007-09-28 2017-06-26 Pfizer Cancer cell targeting using nanoparticles
ES2324009B1 (es) 2007-11-23 2010-05-21 Gp Pharm S.A. Composicion farmaceutica de liberacion sostenida de somatostatina o un analogo suyo.
TWI388591B (zh) * 2008-03-28 2013-03-11 Ind Tech Res Inst 溫度敏感性材料
WO2010005721A2 (en) 2008-06-16 2010-01-14 Bind Biosciences, Inc. Drug loaded polymeric nanoparticles and methods of making and using same
US7993666B2 (en) 2008-04-18 2011-08-09 Warsaw Orthopedic, Inc. Methods and compositions for treating pain comprising a statin
US8956636B2 (en) 2008-04-18 2015-02-17 Warsaw Orthopedic, Inc. Methods and compositions for treating postoperative pain comprosing ketorolac
US20100015049A1 (en) 2008-07-16 2010-01-21 Warsaw Orthopedic, Inc. Methods and compositions for treating postoperative pain comprising nonsteroidal anti-inflammatory agents
US20110097375A1 (en) 2009-10-26 2011-04-28 Warsaw Orthopedic, Inc. Formulation for preventing or reducing bleeding at a surgical site
EA201290497A1 (ru) 2009-12-15 2013-01-30 Байнд Байосайенсиз, Инк. Терапевтические полимерные наночастицы, включающие кортикостероиды, и способы получения таковых
US9295651B2 (en) 2009-12-23 2016-03-29 The Board Of Trustees Of The University Of Illinois Nanoconjugates and nanoconjugate formulations
US20110319473A1 (en) 2010-06-29 2011-12-29 Surmodics, Inc. Compositions and methods for enhancement of nucleic acid delivery
NO2658525T3 (pl) * 2010-12-29 2018-01-27
CN102058909A (zh) 2011-01-18 2011-05-18 复旦大学 聚乙二醇－共聚酯嵌段共聚物防粘连材料及其制备方法与应用
AU2012237260A1 (en) * 2011-03-31 2013-11-14 Ingell Technologies Holding B.V. Biodegradable compositions suitable for controlled release
WO2012131106A1 (en) 2011-03-31 2012-10-04 Ingell Technologies Holding B.V. Biodegradable compositions suitable for controlled release
EP2674167A1 (en) 2012-06-14 2013-12-18 PLS-Design GmbH Controlled activation of complement components for use as endogenous adjuvant
IN2014DN11063A (pl) 2012-06-27 2015-09-25 Medincell
US8954932B2 (en) * 2012-12-11 2015-02-10 International Business Machines Corporation Crash notification between debuggers
AU2014252689A1 (en) 2013-04-11 2015-10-15 Commonwealth Scientific And Industrial Research Organisation Composition for controlled delivery of bioactive agents
KR101512759B1 (ko) * 2013-08-30 2015-04-16 아주대학교산학협력단 이온성 작용기가 곁사슬 또는 말단에 도입된 온도감응성 폴리에틸렌글리콜/폴리에스터 블록 공중합체 및 이의 제조방법
CN103601878B (zh) 2013-11-25 2015-05-13 沈阳药科大学 高稳定性聚乙二醇-聚酯聚合物及其应用
EP2918262B1 (en) 2014-03-10 2023-08-09 PLS-Design GmbH Induction of antigen-specific tolerance by peripheral phagocytosis
US20170042855A1 (en) 2014-04-18 2017-02-16 Bind Therapeutics, Inc. Nanoparticles comprising docetaxel for treating cancers having a k-ras mutation
WO2016172042A1 (en) 2015-04-18 2016-10-27 The Texas A&M University System Polymer systems and their applications in diagnostics and drug delivery
EP3095440B1 (en) 2015-05-19 2020-01-15 PLS-Design GmbH Antigen-specific immunotherapy using tolerizing liposomes
US20170209374A1 (en) 2015-09-11 2017-07-27 Pfizer Inc. Methods of controlling the morphology of polymeric nanoparticles
CN108778245B (zh) * 2015-11-16 2022-05-13 美蒂森 一种用于使药物活性成分微粒化和/或靶向滑膜组织的方法
US20170266187A1 (en) 2016-03-15 2017-09-21 Pfizer Inc. Pemetrexed Polymeric Nanoparticles And Methods Of Making And Using Same
CN105878174B (zh) 2016-04-26 2021-06-29 广州帝奇医药技术有限公司 一种固体分散体及其制备方法与应用
CN105878191B (zh) 2016-04-26 2021-01-22 广州帝奇医药技术有限公司 缓释微粒的制备方法、制得的缓释微粒及其应用
CN105963257B (zh) 2016-04-26 2021-01-22 广州帝奇医药技术有限公司 一种缓释微粒的制备方法
CN105963258B (zh) 2016-04-26 2021-01-22 广州帝奇医药技术有限公司 一种缓释微粒的制备方法
US10925837B2 (en) 2016-08-26 2021-02-23 Akina, Inc. Biodegradable polymer formulations for extended efficacy of botulinum toxin
FI3655038T3 (fi) * 2017-07-17 2025-02-11 Medincell S A Farmaseuttinen koostumus

Also Published As

Publication number Publication date
JP7210816B6 (ja) 2023-02-03
EP4574906A3 (en) 2025-09-10
US20200171157A1 (en) 2020-06-04
HUE070046T2 (hu) 2025-05-28
BR112020001031A2 (pt) 2020-07-14
TWI795422B (zh) 2023-03-11
TWI795423B (zh) 2023-03-11
WO2019016234A1 (en) 2019-01-24
ES3015765T3 (en) 2025-05-07
HRP20250339T1 (hr) 2025-05-09
MX2020000618A (es) 2020-09-28
RS66643B1 (sr) 2025-04-30
DK3655017T3 (da) 2025-03-31
EP3655017B1 (en) 2025-01-22
WO2019016236A1 (en) 2019-01-24
JP7205019B6 (ja) 2023-02-03
TW201907956A (zh) 2019-03-01
KR20200032719A (ko) 2020-03-26
TWI795421B (zh) 2023-03-11
EP3655037A1 (en) 2020-05-27
HRP20250087T1 (hr) 2025-03-28
US20200179518A1 (en) 2020-06-11
JP7187738B2 (ja) 2022-12-13
AR113097A1 (es) 2020-01-29
AR113096A1 (es) 2020-01-29
PT3655038T (pt) 2025-02-04
AU2018304881A1 (en) 2020-01-30
IL271986B2 (en) 2023-08-01
JP2020527590A (ja) 2020-09-10
PT3655017T (pt) 2025-03-26
US11801217B2 (en) 2023-10-31
LT3655017T (lt) 2025-04-10
IL271986A (en) 2020-02-27
SMT202500130T1 (it) 2025-05-12
FI3655038T3 (fi) 2025-02-11
LT3655038T (lt) 2025-02-10
JP2020527586A (ja) 2020-09-10
SI3655017T1 (sl) 2025-06-30
HUE070940T2 (hu) 2025-07-28
EA202090161A1 (ru) 2020-06-29
EP4574906A2 (en) 2025-06-25
SI3655038T1 (sl) 2025-05-30
EP3655017A1 (en) 2020-05-27
TW201907954A (zh) 2019-03-01
FI3655017T3 (fi) 2025-03-27
US11612563B2 (en) 2023-03-28
CA3069787A1 (en) 2019-01-24
CN111107840A (zh) 2020-05-05
JP2020527587A (ja) 2020-09-10
ES3010399T3 (en) 2025-04-02
IL271986B1 (en) 2023-04-01
PL3655038T3 (pl) 2025-04-22
DK3655038T3 (da) 2025-02-17
EP3655038B1 (en) 2024-12-18
US20200163873A1 (en) 2020-05-28
AU2018304881B2 (en) 2024-06-20
US11666527B2 (en) 2023-06-06
KR102745079B1 (ko) 2024-12-24
EP3655038A1 (en) 2020-05-27
TW201907955A (zh) 2019-03-01
AR113248A1 (es) 2020-03-11
JP7205019B2 (ja) 2023-01-17
EP3655037B1 (en) 2025-01-22
JP7210816B2 (ja) 2023-01-24
WO2019016233A1 (en) 2019-01-24

Similar Documents

Publication Publication Date Title
IL265260B (en) pharmaceutical preparations
IL265360B (en) Pharmaceutical composition
IL269061A (en) A pharmaceutical preparation containing Selexifag
IL271986A (en) pharmaceutical preparation
IL262654A (en) Pharmacy preparation
IL265349A (en) Pharmaceutical composition
GB201712159D0 (en) Pharmaceutical composition
GB201705303D0 (en) Pharmaceutical compositions
HUE068810T2 (hu) Gyógyászati készítmény
GB201705304D0 (en) Pharmaceutical compositions
IL272419A (en) Pharmaceutical composition
GB201719447D0 (en) Pharmaceutical composition
GB201705306D0 (en) Pharmaceutical compositions
GB201705305D0 (en) Pharmaceutical compositions
PL3646867T3 (pl) Kompozycja farmaceutyczna
PL3454838T3 (pl) Kompozycja farmaceutyczna
GB201615917D0 (en) Pharmaceutical composition
GB201615914D0 (en) Pharmaceutical composition
IL271513A (en) Innovative pharmaceutical composition
GB201615910D0 (en) Pharmaceutical composition
IL265436B (en) Pharmacy preparation
GB201620519D0 (en) Pharmaceutical composition
IL265428A (en) Pharmaceutical composition
GB201708328D0 (en) Pharmaceutical composition
GB201708329D0 (en) Pharmaceutical composition