PL3646886T3 - Leczenie bólu agonistą receptora serotoninowego 3 - Google Patents

Leczenie bólu agonistą receptora serotoninowego 3

Info

Publication number
PL3646886T3
PL3646886T3 PL18823755.6T PL18823755T PL3646886T3 PL 3646886 T3 PL3646886 T3 PL 3646886T3 PL 18823755 T PL18823755 T PL 18823755T PL 3646886 T3 PL3646886 T3 PL 3646886T3
Authority
PL
Poland
Prior art keywords
serotonin
pain
treatment
receptor agonist
agonist
Prior art date
Application number
PL18823755.6T
Other languages
English (en)
Inventor
Shoichi Shimada
Yukiko Yamamoto
Makoto Kondo
Original Assignee
Osaka University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osaka University filed Critical Osaka University
Publication of PL3646886T3 publication Critical patent/PL3646886T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL18823755.6T 2017-06-28 2018-06-27 Leczenie bólu agonistą receptora serotoninowego 3 PL3646886T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017125874 2017-06-28
PCT/JP2018/024404 WO2019004292A1 (ja) 2017-06-28 2018-06-27 セロトニン3受容体アゴニストによる疼痛の治療

Publications (1)

Publication Number Publication Date
PL3646886T3 true PL3646886T3 (pl) 2024-03-04

Family

ID=64741667

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18823755.6T PL3646886T3 (pl) 2017-06-28 2018-06-27 Leczenie bólu agonistą receptora serotoninowego 3

Country Status (8)

Country Link
US (1) US11446290B2 (pl)
EP (1) EP3646886B1 (pl)
JP (1) JP7090344B2 (pl)
CN (1) CN111050800B (pl)
ES (1) ES2960385T3 (pl)
HU (1) HUE064558T2 (pl)
PL (1) PL3646886T3 (pl)
WO (1) WO2019004292A1 (pl)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2459240A1 (fr) 1979-06-21 1981-01-09 Cm Ind Aminopiperidines anorexigenes, procede pour leur preparation, intermediaires dans ledit procede et medicaments qui les contiennent
DE69228017D1 (de) * 1991-03-27 1999-02-11 Sanofi Sa Verwendung von 4-Amino-1-(2-Pyridyl)Piperidinen als 5-HT3-Agonisten zur Behandlung und Verhütung von serotoninergen Dysfunktionen
JPH07145122A (ja) * 1993-11-24 1995-06-06 Mitsui Toatsu Chem Inc N−アルキル−α,β−不飽和カルボン酸アミドの製造方法
US20040191312A1 (en) * 2002-12-31 2004-09-30 Donna Oksenberg 5-HT3 receptor agonists as neuroprotectors
US20070099950A1 (en) * 2003-11-21 2007-05-03 Jongwon Lim Pyridin-4-ylamine compounds useful in the treatment of neuropathic pain
WO2006021343A2 (en) * 2004-08-26 2006-03-02 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with 5-hydroxytryptamine receptor 3a (5-ht3a)
WO2016027757A1 (ja) * 2014-08-18 2016-02-25 国立大学法人大阪大学 新規2-アミノベンゾイル誘導体

Also Published As

Publication number Publication date
JPWO2019004292A1 (ja) 2020-04-30
ES2960385T3 (es) 2024-03-04
EP3646886C0 (en) 2023-10-04
CN111050800B (zh) 2023-04-04
JP7090344B2 (ja) 2022-06-24
US20210145814A1 (en) 2021-05-20
US11446290B2 (en) 2022-09-20
HUE064558T2 (hu) 2024-03-28
EP3646886A4 (en) 2020-05-06
CN111050800A (zh) 2020-04-21
EP3646886B1 (en) 2023-10-04
WO2019004292A1 (ja) 2019-01-03
EP3646886A1 (en) 2020-05-06

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