PL359208A1 - Nowe pochodne chinazoliny, sposób wytwarzania nowych pochodnych chinazoliny i kompozycje farmaceutyczne - Google Patents

Nowe pochodne chinazoliny, sposób wytwarzania nowych pochodnych chinazoliny i kompozycje farmaceutyczne

Info

Publication number
PL359208A1
PL359208A1 PL03359208A PL35920803A PL359208A1 PL 359208 A1 PL359208 A1 PL 359208A1 PL 03359208 A PL03359208 A PL 03359208A PL 35920803 A PL35920803 A PL 35920803A PL 359208 A1 PL359208 A1 PL 359208A1
Authority
PL
Poland
Prior art keywords
quinosoline
new derivatives
production
pharmaceutical preparations
derivatives
Prior art date
Application number
PL03359208A
Other languages
English (en)
Inventor
Solo Goldstein
Alain Dhainaut
Andre Tizot
Jean-Luc Fauchere
Nathalie Kucharczyk
John Hickman
Alain Pierre
Gordon Tucker
Laurence Kraus-Berthier
Original Assignee
Les Laboratoires Servier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Servier filed Critical Les Laboratoires Servier
Publication of PL359208A1 publication Critical patent/PL359208A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL03359208A 2002-03-18 2003-03-17 Nowe pochodne chinazoliny, sposób wytwarzania nowych pochodnych chinazoliny i kompozycje farmaceutyczne PL359208A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0203299A FR2837201A1 (fr) 2002-03-18 2002-03-18 Nouveaux composes derives de la quinazoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
PL359208A1 true PL359208A1 (pl) 2003-09-22

Family

ID=8871501

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03359208A PL359208A1 (pl) 2002-03-18 2003-03-17 Nowe pochodne chinazoliny, sposób wytwarzania nowych pochodnych chinazoliny i kompozycje farmaceutyczne

Country Status (16)

Country Link
US (1) US20030199530A1 (pl)
EP (1) EP1346992A1 (pl)
JP (1) JP2003292491A (pl)
KR (1) KR20030076350A (pl)
CN (1) CN1445226A (pl)
AR (1) AR038988A1 (pl)
AU (1) AU2003201326A1 (pl)
BR (1) BR0300698A (pl)
CA (1) CA2423259A1 (pl)
EA (1) EA200300272A1 (pl)
FR (1) FR2837201A1 (pl)
MX (1) MXPA03002088A (pl)
NO (1) NO20031219L (pl)
NZ (1) NZ524771A (pl)
PL (1) PL359208A1 (pl)
ZA (1) ZA200302159B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1621539A1 (en) * 2004-07-27 2006-02-01 Aventis Pharma S.A. Heterocycle -substituted cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors
EP1741709A1 (en) * 2005-06-28 2007-01-10 Sanofi-Aventis Deutschland GmbH Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals
US7834023B2 (en) * 2006-09-20 2010-11-16 Portola Pharmaceuticals, Inc. Substituted dihydroquinazolines as platelet ADP receptor inhibitors
LT2420498T (lt) * 2006-09-26 2017-10-25 Celgene Corporation 5-pakeistieji chinazolinono dariniai, kaip priešvėžiniai agentai
JP5634263B2 (ja) * 2007-08-16 2014-12-03 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング キナゾリンジオンキマーゼ阻害剤
CN103288761B (zh) * 2012-02-25 2017-08-11 浙江华海药业股份有限公司 一种合成1,2,3,4‑喹唑啉‑2,4‑二酮衍生物的新方法
CN102993105B (zh) * 2012-12-19 2014-06-11 西南大学 1-甲基-2,4-喹唑啉二酮衍生物及其制备方法和应用
TW201623257A (zh) * 2014-05-09 2016-07-01 奧利安公司 藥理活性之喹唑啉二酮衍生物
RU2692774C2 (ru) * 2014-08-29 2019-06-27 Дайсел Корпорэйшн Имидазольное соединение, жидкость для обработки металлической поверхности, способ обработки металлической поверхности и способ изготовления ламината
WO2023158845A1 (en) * 2022-02-18 2023-08-24 Musc Foundation For Researchdevelopment Small molecules targeting the vdac nadh-binding pocket to modulate cancer metabolism
EP4608817A1 (en) * 2022-10-24 2025-09-03 The Regents Of The University Of California Compounds and methods for treating cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0293500A1 (en) * 1987-06-01 1988-12-07 American Cyanamid Company 3-heteroalkyl-2,4.quinzaoline-diones
BR9809398A (pt) * 1997-04-25 2000-06-13 Janssen Pharmaceutica Nv Quinazolinonas que inibem a farnesil transferase

Also Published As

Publication number Publication date
FR2837201A1 (fr) 2003-09-19
NO20031219D0 (no) 2003-03-17
NZ524771A (en) 2003-08-29
BR0300698A (pt) 2004-09-08
EA200300272A1 (ru) 2003-10-30
NO20031219L (no) 2003-09-19
CN1445226A (zh) 2003-10-01
KR20030076350A (ko) 2003-09-26
EP1346992A1 (fr) 2003-09-24
ZA200302159B (en) 2003-09-23
AU2003201326A1 (en) 2003-10-02
JP2003292491A (ja) 2003-10-15
US20030199530A1 (en) 2003-10-23
CA2423259A1 (fr) 2003-09-18
AR038988A1 (es) 2005-02-02
MXPA03002088A (es) 2004-12-07

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)