PL3525774T3 - Leczenie lazofoksyfenem raka piersi er+ - Google Patents

Leczenie lazofoksyfenem raka piersi er+

Info

Publication number
PL3525774T3
PL3525774T3 PL17791239T PL17791239T PL3525774T3 PL 3525774 T3 PL3525774 T3 PL 3525774T3 PL 17791239 T PL17791239 T PL 17791239T PL 17791239 T PL17791239 T PL 17791239T PL 3525774 T3 PL3525774 T3 PL 3525774T3
Authority
PL
Poland
Prior art keywords
breast cancer
lasofoxifene
treatment
lasofoxifene treatment
breast
Prior art date
Application number
PL17791239T
Other languages
English (en)
Inventor
Kaitlyn Andreano
Ching-Yi Chang
Donald P. Mcdonnell
Stephanie L. Gaillard
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Publication of PL3525774T3 publication Critical patent/PL3525774T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4021-aryl substituted, e.g. piretanide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
PL17791239T 2016-10-11 2017-10-10 Leczenie lazofoksyfenem raka piersi er+ PL3525774T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662406859P 2016-10-11 2016-10-11
US201762457759P 2017-02-10 2017-02-10
US201762502299P 2017-05-05 2017-05-05
PCT/US2017/055970 WO2018093484A1 (en) 2016-10-11 2017-10-10 Lasofoxifene treatment of er+ breast cancer
EP17791239.1A EP3525774B1 (en) 2016-10-11 2017-10-10 Lasofoxifene treatment of er+ breast cancer

Publications (1)

Publication Number Publication Date
PL3525774T3 true PL3525774T3 (pl) 2022-04-25

Family

ID=60186386

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17791239T PL3525774T3 (pl) 2016-10-11 2017-10-10 Leczenie lazofoksyfenem raka piersi er+

Country Status (20)

Country Link
US (5) US20180098963A1 (pl)
EP (2) EP3525774B1 (pl)
JP (4) JP6892151B2 (pl)
KR (5) KR102623130B1 (pl)
CN (3) CN112353796A (pl)
AU (2) AU2017360365B2 (pl)
BR (1) BR112019007254A2 (pl)
CA (1) CA3040266A1 (pl)
DK (1) DK3525774T3 (pl)
ES (1) ES2909576T3 (pl)
IL (2) IL284875B (pl)
MX (2) MX2019004184A (pl)
NZ (1) NZ752443A (pl)
PL (1) PL3525774T3 (pl)
PT (1) PT3525774T (pl)
RU (1) RU2019114079A (pl)
SG (2) SG10201913951YA (pl)
TW (2) TWI729227B (pl)
WO (2) WO2018093484A1 (pl)
ZA (1) ZA201902454B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10449195B2 (en) 2016-03-29 2019-10-22 Shenzhen Pharmacin Co., Ltd. Pharmaceutical formulation of palbociclib and a preparation method thereof
PL3525774T3 (pl) 2016-10-11 2022-04-25 Duke University Leczenie lazofoksyfenem raka piersi er+
WO2019199891A1 (en) 2018-04-10 2019-10-17 Duke University Lasofoxifene treatment of breast cancer
CN114306245A (zh) 2020-09-29 2022-04-12 深圳市药欣生物科技有限公司 无定形固体分散体的药物组合物及其制备方法
GB202116903D0 (en) 2021-11-18 2022-01-05 Sermonix Pharmaceuticals Inc Lasofoxifene treatment of aromatase-resistant er+ cancer
US20230381138A1 (en) * 2022-05-25 2023-11-30 Sermonix Pharmaceuticals, Inc. Lasofoxifene combination treatment of er+ breast cancer that has progressed on a cdk4/6 inhibitor

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Also Published As

Publication number Publication date
JP7247241B2 (ja) 2023-03-28
AU2017360365A1 (en) 2019-05-02
IL265938B (en) 2021-08-31
MX2019004184A (es) 2019-09-27
BR112019007254A2 (pt) 2019-07-02
KR102462433B1 (ko) 2022-11-03
ZA201902454B (en) 2022-09-28
KR102531354B1 (ko) 2023-05-11
ES2909576T3 (es) 2022-05-09
US20190151286A1 (en) 2019-05-23
TW202313005A (zh) 2023-04-01
EP3525774A1 (en) 2019-08-21
KR20210096316A (ko) 2021-08-04
US10905659B2 (en) 2021-02-02
US20180221335A1 (en) 2018-08-09
SG10201913951YA (en) 2020-03-30
US20180098963A1 (en) 2018-04-12
MX2021013911A (es) 2022-01-18
JP7418052B2 (ja) 2024-01-19
CN110099680B (zh) 2021-02-05
WO2018071440A1 (en) 2018-04-19
WO2018093484A1 (en) 2018-05-24
AU2017360365B2 (en) 2022-08-04
DK3525774T3 (da) 2022-03-14
JP2024026527A (ja) 2024-02-28
JP2019529581A (ja) 2019-10-17
KR20240007720A (ko) 2024-01-16
RU2019114079A3 (pl) 2021-07-23
JP2021073316A (ja) 2021-05-13
US20230233490A1 (en) 2023-07-27
CN112933082A (zh) 2021-06-11
EP4035662A1 (en) 2022-08-03
IL284875A (en) 2021-08-31
TW201817422A (zh) 2018-05-16
CN110099680A (zh) 2019-08-06
US20210361596A1 (en) 2021-11-25
IL284875B (en) 2022-07-01
KR102285453B1 (ko) 2021-08-05
KR102623130B1 (ko) 2024-01-10
JP2023033415A (ja) 2023-03-10
CN112353796A (zh) 2021-02-12
TWI790672B (zh) 2023-01-21
KR20220151017A (ko) 2022-11-11
SG11201903236SA (en) 2019-05-30
KR20190092377A (ko) 2019-08-07
TW202137980A (zh) 2021-10-16
US20190231718A1 (en) 2019-08-01
JP6892151B2 (ja) 2021-06-23
US10258604B2 (en) 2019-04-16
KR20230042390A (ko) 2023-03-28
RU2019114079A (ru) 2020-11-13
AU2022246480A1 (en) 2022-12-08
IL265938A (en) 2019-05-30
PT3525774T (pt) 2022-03-30
EP3525774B1 (en) 2021-12-29
CA3040266A1 (en) 2018-05-24
NZ752443A (en) 2022-11-25
TWI729227B (zh) 2021-06-01

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