PL3468997T3 - Leczenie chorób związanych z lgG4 przeciwciałami anty-CD19 wiążącymi się krzyżowo z CD32b - Google Patents
Leczenie chorób związanych z lgG4 przeciwciałami anty-CD19 wiążącymi się krzyżowo z CD32bInfo
- Publication number
- PL3468997T3 PL3468997T3 PL17731411.9T PL17731411T PL3468997T3 PL 3468997 T3 PL3468997 T3 PL 3468997T3 PL 17731411 T PL17731411 T PL 17731411T PL 3468997 T3 PL3468997 T3 PL 3468997T3
- Authority
- PL
- Poland
- Prior art keywords
- cd32b
- igg4
- antibodies
- link
- treatment
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/522—CH1 domain
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/72—Increased effector function due to an Fc-modification
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Otolaryngology (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662347419P | 2016-06-08 | 2016-06-08 | |
| US201662399896P | 2016-09-26 | 2016-09-26 | |
| US201662421261P | 2016-11-12 | 2016-11-12 | |
| PCT/US2017/036635 WO2017214452A1 (en) | 2016-06-08 | 2017-06-08 | Treatment of igg4-related diseases with anti-cd19 antibodies crossbinding to cd32b |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3468997T3 true PL3468997T3 (pl) | 2024-12-16 |
Family
ID=59078236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17731411.9T PL3468997T3 (pl) | 2016-06-08 | 2017-06-08 | Leczenie chorób związanych z lgG4 przeciwciałami anty-CD19 wiążącymi się krzyżowo z CD32b |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11365256B2 (pl) |
| EP (2) | EP3468997B1 (pl) |
| JP (3) | JP7148504B2 (pl) |
| CA (1) | CA3026880A1 (pl) |
| DK (1) | DK3468997T5 (pl) |
| ES (1) | ES2963807T3 (pl) |
| FI (1) | FI3468997T3 (pl) |
| HU (1) | HUE064454T2 (pl) |
| PL (1) | PL3468997T3 (pl) |
| PT (1) | PT3468997T (pl) |
| WO (1) | WO2017214452A1 (pl) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2017014822A (es) | 2015-05-18 | 2018-04-30 | Tcr2 Therapeutics Inc | Composiciones y métodos para la reprogramación del tcr con proteínas de fusión. |
| CA3026880A1 (en) | 2016-06-08 | 2017-12-14 | Xencor, Inc. | Methods and compositions for inhibiting cd32b expressing cells in igg4-related diseases |
| CA3032498A1 (en) | 2016-08-02 | 2018-02-08 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| MX2019003899A (es) | 2016-10-07 | 2019-08-14 | Tcr2 Therapeutics Inc | Composiciones y metodos para reprogramacion de receptores de linfocitos t mediante el uso de proteinas de fusion. |
| EP3544996A2 (en) | 2016-11-22 | 2019-10-02 | TCR2 Therapeutics Inc. | Compositions and methods for tcr reprogramming using fusion proteins |
| BR112020018173A2 (pt) * | 2018-03-09 | 2021-04-27 | TCR2 Therapeutics Inc. | composições e métodos para reprogramação de tcr usando proteínas de fusão |
| CN108647620B (zh) * | 2018-05-03 | 2020-05-26 | 武汉科技大学 | 一种基于伽马变换的韦伯人脸的光照归一化方法 |
| WO2020072653A1 (en) * | 2018-10-02 | 2020-04-09 | Zack Debra | Methods and compositions for treating igg4-related diseases |
| SG11202109118XA (en) * | 2019-02-26 | 2021-09-29 | Equillium Inc | Anti-cd6 antibody compositions and methods for treating lupus |
| CN110045126B (zh) * | 2019-04-03 | 2022-08-09 | 中国医学科学院北京协和医院 | 一种用于诊断自身免疫性胰腺炎的生物标志物及其用途 |
| CN110045127A (zh) * | 2019-04-03 | 2019-07-23 | 中国医学科学院北京协和医院 | 一种IgG4相关性疾病多器官受累的生物标志物及其用途 |
| AR121370A1 (es) * | 2020-02-28 | 2022-06-01 | Lilly Co Eli | Anticuerpos anti-cd19 humano |
| AU2021408091A1 (en) * | 2020-12-23 | 2023-07-13 | Genmab A/S | Modified immunoglobulin with affinity for fcgammariib and method of use thereof |
| MX2024001826A (es) * | 2021-08-11 | 2024-05-08 | Viela Bio Inc | Inebilizumab y metodos de uso del mismo en el tratamiento o prevencion de la enfermedad relacionada con igg4. |
| EP4531914A1 (en) * | 2022-06-03 | 2025-04-09 | Zenas Biopharma, Inc. | Methods and compositions for treating igg4- related diseases |
| WO2024092031A1 (en) | 2022-10-25 | 2024-05-02 | Seismic Therapeutic, Inc. | VARIANT IgG FC POLYPEPTIDES AND USES THEREOF |
| TW202540200A (zh) * | 2023-12-01 | 2025-10-16 | 美商基利科學股份有限公司 | 抗fap-light融合蛋白及其用途 |
| WO2025155844A1 (en) * | 2024-01-17 | 2025-07-24 | Zenas Biopharma, Inc. | Methods and compositions for treating systemic lupus erythematous (sle) |
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| US5686072A (en) | 1992-06-17 | 1997-11-11 | Board Of Regents, The University Of Texas | Epitope-specific monoclonal antibodies and immunotoxins and uses thereof |
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| US5587459A (en) | 1994-08-19 | 1996-12-24 | Regents Of The University Of Minnesota | Immunoconjugates comprising tyrosine kinase inhibitors |
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| US6214388B1 (en) | 1994-11-09 | 2001-04-10 | The Regents Of The University Of California | Immunoliposomes that optimize internalization into target cells |
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2017
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- 2017-06-08 DK DK17731411.9T patent/DK3468997T5/da active
- 2017-06-08 EP EP17731411.9A patent/EP3468997B1/en active Active
- 2017-06-08 EP EP23194274.9A patent/EP4371570A3/en active Pending
- 2017-06-08 US US15/618,051 patent/US11365256B2/en active Active
- 2017-06-08 PT PT177314119T patent/PT3468997T/pt unknown
- 2017-06-08 JP JP2019516918A patent/JP7148504B2/ja active Active
- 2017-06-08 WO PCT/US2017/036635 patent/WO2017214452A1/en not_active Ceased
- 2017-06-08 ES ES17731411T patent/ES2963807T3/es active Active
- 2017-06-08 PL PL17731411.9T patent/PL3468997T3/pl unknown
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Also Published As
| Publication number | Publication date |
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| JP2019525949A (ja) | 2019-09-12 |
| US20250340650A1 (en) | 2025-11-06 |
| EP4371570A2 (en) | 2024-05-22 |
| PT3468997T (pt) | 2023-12-07 |
| US11365256B2 (en) | 2022-06-21 |
| JP2022177224A (ja) | 2022-11-30 |
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| US20170355766A1 (en) | 2017-12-14 |
| DK3468997T5 (da) | 2024-09-09 |
| CA3026880A1 (en) | 2017-12-14 |
| US20220389098A1 (en) | 2022-12-08 |
| EP3468997A1 (en) | 2019-04-17 |
| ES2963807T3 (es) | 2024-04-02 |
| HUE064454T2 (hu) | 2024-03-28 |
| EP3468997B1 (en) | 2023-09-13 |
| JP2023144078A (ja) | 2023-10-06 |
| EP4371570A3 (en) | 2024-07-17 |
| JP7148504B2 (ja) | 2022-10-05 |
| WO2017214452A1 (en) | 2017-12-14 |
| JP7660269B2 (ja) | 2025-04-11 |
| FI3468997T3 (fi) | 2023-10-31 |
| US12509518B2 (en) | 2025-12-30 |
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