PL345309A1 - Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient - Google Patents

Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient

Info

Publication number
PL345309A1
PL345309A1 PL99345309A PL34530999A PL345309A1 PL 345309 A1 PL345309 A1 PL 345309A1 PL 99345309 A PL99345309 A PL 99345309A PL 34530999 A PL34530999 A PL 34530999A PL 345309 A1 PL345309 A1 PL 345309A1
Authority
PL
Poland
Prior art keywords
preparation
pharmaceutical composition
active ingredient
same
composition containing
Prior art date
Application number
PL99345309A
Other languages
English (en)
Inventor
Bela Agai
Jozsef Reiter
Gyula Simig
Endre Rivo
Zoltan Tamas Nagy
Levente Ondi
Megyeri Katalin Ivanicsne
Kovacs Aniko Miklosne
Gyonos Ildiko Nagyne
Szabolcs Kertesz
Gabor Szenasi
Eva Schmidt
Katalin Pallagi
Istvan Gacsalyi
Istvan Gyertyan
Tamas Szabados
Gyorgy Levay
Andras Egyed
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU9801086A external-priority patent/HUP9801086A3/hu
Priority claimed from HU9801085A external-priority patent/HUP9801085A3/hu
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of PL345309A1 publication Critical patent/PL345309A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL99345309A 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient PL345309A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HU9801086A HUP9801086A3 (en) 1998-05-14 1998-05-14 Benzofurane derivatives, pharmaceutical compositions containing them as active ingredient process for producing the active ingredient and intermediates of them
HU9801085A HUP9801085A3 (en) 1998-05-14 1998-05-14 Piperazinyl-alkyl-benzofurane derivatives, pharmaceutical compositions containing them as active ingredient and process for producing the active ingredient
PCT/HU1999/000038 WO1999058527A2 (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient

Publications (1)

Publication Number Publication Date
PL345309A1 true PL345309A1 (en) 2001-12-03

Family

ID=89996544

Family Applications (1)

Application Number Title Priority Date Filing Date
PL99345309A PL345309A1 (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient

Country Status (9)

Country Link
EP (1) EP1077973A2 (xx)
JP (1) JP2002514643A (xx)
KR (1) KR20010043618A (xx)
AU (1) AU753706B2 (xx)
CA (1) CA2332275A1 (xx)
HR (1) HRP20000750A2 (xx)
PL (1) PL345309A1 (xx)
SK (1) SK17212000A3 (xx)
WO (1) WO1999058527A2 (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6835733B2 (en) 1999-12-20 2004-12-28 Eli Lilly And Company Tropane linked benzofuran derivatives
WO2001046177A1 (en) * 1999-12-20 2001-06-28 Eli Lilly And Company Benzofuran derivatives
FR2845992B1 (fr) * 2002-10-16 2005-02-04 Pf Medicament Derives de 3-(cyclopenten-1yl)-benzyl-ou3-(cyclopenten-1yl)- heteroarylmethyl-amines et leur utilisation a titre de medicaments pour le traitement de la schizophrenie
WO2006088963A1 (en) * 2005-02-17 2006-08-24 Bayer Cropscience Ag Improved process for preparing (disubstitutedpropenyl) phenylalkyl substituted dihydrobenzofurans
HU230729B1 (hu) * 2007-05-30 2017-12-28 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Új, szelektív 5HT7-receptorgátló benzofurán-származékok és eljárás előállításukra
HU230761B1 (hu) * 2007-05-30 2018-03-28 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Új, szelektív 5HT6-receptorgátló benzofurán-származékok és eljárás előállításukra
GB201312499D0 (en) * 2013-07-12 2013-08-28 Isis Innovation Therapeutic compounds

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH474511A (xx) * 1966-06-24 1969-06-30 F. Hoffmann-La Roche & Co. Aktiengesellschaft
DE2235597A1 (de) * 1972-07-20 1974-01-31 Boehringer Mannheim Gmbh 1-eckige klammer auf 3-(5,6,7,8tetrahydronaphth-1-yl-oxy) -propyl eckige klammer zu -piperazin-derivate und verfahren zu ihrer herstellung
FR2353291A1 (fr) * 1976-05-31 1977-12-30 Parcor Nouveaux derives du benzofuranne
US4110536A (en) * 1977-04-18 1978-08-29 Miles Laboratories, Inc. Derivatives of 5-(indol-3-yl)hydantoin
US4612309A (en) * 1984-10-23 1986-09-16 William H. Rorer, Inc. Antisecretory bicyclic benzo-oxy heterocyclic ethers and thioethers
US4966907A (en) * 1988-08-12 1990-10-30 Merck & Co., Inc. 6-substituted 5-hydroxy-2,3-dihydrobenzofurans as inhibitors of leukotriene biosynthesis
GB9005014D0 (en) * 1990-03-06 1990-05-02 Janssen Pharmaceutica Nv N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives
FR2681319B1 (fr) * 1991-09-12 1995-02-17 Synthelabo Derives de 1-(phenoxyalkyl)piperidine, leur preparation et leur application en therapeutique.
HU218698B (hu) * 1994-09-27 2000-11-28 Janssen Pharmaceutica N.V. Gyógyászati hatású N-szubsztituált piperidinil-(biciklusos benzoát)-származékok, intermedierjeik, előállításuk és alkalmazásuk
TW490465B (en) * 1994-11-24 2002-06-11 Janssen Pharmaceutica Nv Enterokinetic benzamide, the preparation process and the pharmaceutical compositions thereof
GB9507882D0 (en) * 1995-04-18 1995-05-31 Pharmacia Spa Substituted dihydrobenzofuran derivatives as 5-ht4 agonists
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
NZ330263A (en) * 1996-02-15 1999-06-29 Janssen Pharmaceutica Nv Esters of 3-hydroxy-piperidinemethanol derivatives to improve gastric emptying

Also Published As

Publication number Publication date
JP2002514643A (ja) 2002-05-21
WO1999058527A2 (en) 1999-11-18
KR20010043618A (ko) 2001-05-25
WO1999058527A3 (en) 2000-01-27
CA2332275A1 (en) 1999-11-18
SK17212000A3 (sk) 2001-05-10
HRP20000750A2 (en) 2001-06-30
EP1077973A2 (en) 2001-02-28
AU753706B2 (en) 2002-10-24
AU4052999A (en) 1999-11-29

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