WO1999058527A3 - Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient - Google Patents

Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient Download PDF

Info

Publication number
WO1999058527A3
WO1999058527A3 PCT/HU1999/000038 HU9900038W WO9958527A3 WO 1999058527 A3 WO1999058527 A3 WO 1999058527A3 HU 9900038 W HU9900038 W HU 9900038W WO 9958527 A3 WO9958527 A3 WO 9958527A3
Authority
WO
WIPO (PCT)
Prior art keywords
same
pharmaceutical composition
active ingredient
benzofuran derivatives
derivatives
Prior art date
Application number
PCT/HU1999/000038
Other languages
French (fr)
Other versions
WO1999058527A2 (en
Inventor
Bela Agai
Andras Egyed
Istvan Gacsalyi
Istvan Gyertyan
Megyeri Katalin Ivanicsne
Szabolcs Kertesz
Gyoergy Levay
Kovacs Aniko Miklosne
Zoltan Tamas Nagy
Gyoenoes Ildiko Nagyne
Levente Ondi
Katalin Pallagi
Jozsef Reiter
Endre Rivo
Eva Schmidt
Gyula Simig
Tamas Szabados
Gabor Szenasi
Original Assignee
Bela Agai
Andras Egyed
Egyt Gyogyszervegyeszeti Gyar
Istvan Gacsalyi
Istvan Gyertyan
Megyeri Katalin Ivanicsne
Szabolcs Kertesz
Gyoergy Levay
Kovacs Aniko Miklosne
Zoltan Tamas Nagy
Gyoenoes Ildiko Nagyne
Levente Ondi
Katalin Pallagi
Jozsef Reiter
Endre Rivo
Eva Schmidt
Gyula Simig
Tamas Szabados
Gabor Szenasi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to HUP9801085 priority Critical
Priority to HU9801085A priority patent/HU9801085A3/en
Priority to HU9801086A priority patent/HU9801086A3/en
Priority to HUP9801086 priority
Application filed by Bela Agai, Andras Egyed, Egyt Gyogyszervegyeszeti Gyar, Istvan Gacsalyi, Istvan Gyertyan, Megyeri Katalin Ivanicsne, Szabolcs Kertesz, Gyoergy Levay, Kovacs Aniko Miklosne, Zoltan Tamas Nagy, Gyoenoes Ildiko Nagyne, Levente Ondi, Katalin Pallagi, Jozsef Reiter, Endre Rivo, Eva Schmidt, Gyula Simig, Tamas Szabados, Gabor Szenasi filed Critical Bela Agai
Publication of WO1999058527A2 publication Critical patent/WO1999058527A2/en
Publication of WO1999058527A3 publication Critical patent/WO1999058527A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Abstract

The invention refers to novel benzofuran derivatives of formula (I), a process for preparing these compounds and to pharmaceutical compositions containing these active substances.
PCT/HU1999/000038 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient WO1999058527A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
HUP9801085 1998-05-14
HU9801085A HU9801085A3 (en) 1998-05-14 1998-05-14 Piperazinyl-alkyl-benzofurane derivatives, pharmaceutical compositions containing them as active ingredient and process for producing the active ingredient
HU9801086A HU9801086A3 (en) 1998-05-14 1998-05-14 Benzofurane derivatives, pharmaceutical compositions containing them as active ingredient process for producing the active ingredient and intermediates of them
HUP9801086 1998-05-14

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
PL99345309A PL345309A1 (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
CA002332275A CA2332275A1 (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
EP99923772A EP1077973A2 (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
KR1020007012773A KR20010043618A (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
JP2000548331A JP2002514643A (en) 1998-05-14 1999-05-13 A benzofuran derivative, a pharmaceutical composition containing the same and a method for producing the active ingredient thereof.
SK1721-2000A SK17212000A3 (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
AU40529/99A AU753706B2 (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
HR20000750A HRP20000750A2 (en) 1998-05-14 2000-11-03 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US09700345 A-371-Of-International 2000-12-27
US10/736,714 Division US20040186170A1 (en) 1998-05-14 2003-12-15 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient

Publications (2)

Publication Number Publication Date
WO1999058527A2 WO1999058527A2 (en) 1999-11-18
WO1999058527A3 true WO1999058527A3 (en) 2000-01-27

Family

ID=26318308

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/HU1999/000038 WO1999058527A2 (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient

Country Status (9)

Country Link
EP (1) EP1077973A2 (en)
JP (1) JP2002514643A (en)
KR (1) KR20010043618A (en)
AU (1) AU753706B2 (en)
CA (1) CA2332275A1 (en)
HR (1) HRP20000750A2 (en)
PL (1) PL345309A1 (en)
SK (1) SK17212000A3 (en)
WO (1) WO1999058527A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001046186A1 (en) * 1999-12-20 2001-06-28 Eli Lilly And Company Benzofuran derivatives
EP1246822A1 (en) * 1999-12-20 2002-10-09 Eli Lilly And Company Benzofuran derivatives
FR2845992B1 (en) * 2002-10-16 2005-02-04 Pf Medicament 3- (CYCLOPENTEN-1YL) -BENZYL-OU3- (CYCLOPENTEN-1YL) -HETEROARYLMETHYL-AMINE DERIVATIVES AND THEIR USE AS MEDICAMENTS FOR THE TREATMENT OF SCHIZOPHRENIA
CN101120008A (en) * 2005-02-17 2008-02-06 拜尔农作物科学股份公司 Improved process for preparing (disubstitutedpropenyl) phenylalkyl substituted dihydrobenzofurans
HU230761B1 (en) * 2007-05-30 2018-03-28 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság New benzofuran derivatives as selective inhibitors of 5-ht6 and process for their preparation
HU230729B1 (en) * 2007-05-30 2017-12-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag New benzofuran derivatives as selective inhibitors of 5-ht7 and process for their preparation
GB201312499D0 (en) * 2013-07-12 2013-08-28 Isis Innovation Therapeutic compounds

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH474511A (en) * 1966-06-24 1969-06-30 F. Hoffmann-La Roche & Co. Aktiengesellschaft
DE2235597A1 (en) * 1972-07-20 1974-01-31 Boehringer Mannheim Gmbh SINGLE SQUARE CLIP ON 3- (5,6,7,8TETRAHYDRONAPHTH-1-YL-OXY) -PROPYL SQUARE CLIP FOR -PIPERAZINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION
DE2724083A1 (en) * 1976-05-31 1978-02-23 Parcor BENZO (B) FURANE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEANS CONTAINING THE SAME
US4110536A (en) * 1977-04-18 1978-08-29 Miles Laboratories, Inc. Derivatives of 5-(indol-3-yl)hydantoin
WO1986002550A1 (en) * 1984-10-23 1986-05-09 Rorer International (Overseas) Inc. Bicyclic benzo-oxy heterocyclic ethers and thioethers as h2-receptors antagonists
GB2221680A (en) * 1988-08-12 1990-02-14 Merck & Co Inc Novel 5-hydroxy-2,3-dihydrobenzorfurans as inhibitors of leukotriene bio- synthesis
EP0445862A2 (en) * 1990-03-06 1991-09-11 Janssen Pharmaceutica N.V. N-(4-piperidinyl)(dihydrobenzofuran or dihydro-2H-benzopyran)carboxamide derivatives
FR2681319A1 (en) * 1991-09-12 1993-03-19 Synthelabo 1-(Phenoxyalkyl)piperidine derivatives, their preparation and their application in therapeutics
WO1996010027A1 (en) * 1994-09-27 1996-04-04 Janssen Pharmaceutica N.V. N-substituted piperidinyl bicyclic benzoate derivatives
WO1996016060A1 (en) * 1994-11-24 1996-05-30 Janssen Pharmaceutica N.V. Enterokinetic benzamide
WO1996033186A1 (en) * 1995-04-18 1996-10-24 Pharmacia & Upjohn S.P.A. Substituted dihydrobenzofuran derivatives as 5-ht4 agonists
WO1997023216A1 (en) * 1995-12-22 1997-07-03 Warner-Lambert Company 4-substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
WO1997030031A1 (en) * 1996-02-15 1997-08-21 Janssen Pharmaceutica N.V. Esters of 3-hydroxy-piperidinemethanol derivatives

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH474511A (en) * 1966-06-24 1969-06-30 F. Hoffmann-La Roche & Co. Aktiengesellschaft
DE2235597A1 (en) * 1972-07-20 1974-01-31 Boehringer Mannheim Gmbh SINGLE SQUARE CLIP ON 3- (5,6,7,8TETRAHYDRONAPHTH-1-YL-OXY) -PROPYL SQUARE CLIP FOR -PIPERAZINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION
DE2724083A1 (en) * 1976-05-31 1978-02-23 Parcor BENZO (B) FURANE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEANS CONTAINING THE SAME
US4110536A (en) * 1977-04-18 1978-08-29 Miles Laboratories, Inc. Derivatives of 5-(indol-3-yl)hydantoin
WO1986002550A1 (en) * 1984-10-23 1986-05-09 Rorer International (Overseas) Inc. Bicyclic benzo-oxy heterocyclic ethers and thioethers as h2-receptors antagonists
GB2221680A (en) * 1988-08-12 1990-02-14 Merck & Co Inc Novel 5-hydroxy-2,3-dihydrobenzorfurans as inhibitors of leukotriene bio- synthesis
EP0445862A2 (en) * 1990-03-06 1991-09-11 Janssen Pharmaceutica N.V. N-(4-piperidinyl)(dihydrobenzofuran or dihydro-2H-benzopyran)carboxamide derivatives
FR2681319A1 (en) * 1991-09-12 1993-03-19 Synthelabo 1-(Phenoxyalkyl)piperidine derivatives, their preparation and their application in therapeutics
WO1996010027A1 (en) * 1994-09-27 1996-04-04 Janssen Pharmaceutica N.V. N-substituted piperidinyl bicyclic benzoate derivatives
WO1996016060A1 (en) * 1994-11-24 1996-05-30 Janssen Pharmaceutica N.V. Enterokinetic benzamide
WO1996033186A1 (en) * 1995-04-18 1996-10-24 Pharmacia & Upjohn S.P.A. Substituted dihydrobenzofuran derivatives as 5-ht4 agonists
WO1997023216A1 (en) * 1995-12-22 1997-07-03 Warner-Lambert Company 4-substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
WO1997030031A1 (en) * 1996-02-15 1997-08-21 Janssen Pharmaceutica N.V. Esters of 3-hydroxy-piperidinemethanol derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J. B. HANSEN ET AL., EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 32, no. 2, 1997, pages 103 - 111, XP004054789 *

Also Published As

Publication number Publication date
WO1999058527A2 (en) 1999-11-18
AU4052999A (en) 1999-11-29
KR20010043618A (en) 2001-05-25
HRP20000750A2 (en) 2001-06-30
JP2002514643A (en) 2002-05-21
EP1077973A2 (en) 2001-02-28
CA2332275A1 (en) 1999-11-18
SK17212000A3 (en) 2001-05-10
AU753706B2 (en) 2002-10-24
PL345309A1 (en) 2001-12-03

Similar Documents

Publication Publication Date Title
AU2002321669A1 (en) Novel 2H-pyridazine-3-one derivatives, pharmaceutical compositions containing the same and a process for the preparation of the active ingredient
CA2414018A1 (en) 2-aminocarbonyl-9h-purine derivatives
HU0102422A3 (en) Isothiazole derivatives useful as anticancer agents, pharmaceutical compositions containing such compounds and processes for their preparation
HU9802822A3 (en) Halobenzimidazol derivatives, intermediates, preparation thereof and microbocide compositions containing these compounds as active ingredients
SI1417206T1 (en) Novel 2h-pyridazine-3-one derivatives, pharmaceutical compositions containing the same and a process for the preparation of the active ingredient
HU9601033A2 (en) Benzofurane derivatives, process for their preparation, use of them as intermediate and pharmaceutical compositions containing the compounds
WO2001032646A3 (en) Sulfonamide derivatives
CA2402431A1 (en) 1,2,3,4-tetrahydroisoquinoline derivatives
WO2002048147A3 (en) Pyrazolopyridines
WO2001029055A3 (en) Novel oligosaccharides, preparation method and pharmaceutical compositions containing same
AU4949800A (en) 2-arylpurine-9-acetamide derivatives, process for the preparation thereof, medicinal compositions containing the same and intermediates of the derivatives
WO2002048148A3 (en) Pyrazolopyridine derivatives
HU0204157A3 (en) 1,3-dihydro-2h-indol-2-one derivatives, process for preparation of the compounds and pharmaceutical compositions containing the same
HU9700159A3 (en) Benzylsulfide derivatives,intermediates thereof, process for preparation thereof and insecticide compositions containing these compounds as active ingredients
WO2001053257A3 (en) Compounds having hypolipedemic and hypocholesteremic activities, process for their preparation and pharmaceutical compositions containing them
WO2001000617A3 (en) Novel piperazinylalkylthiopyrimidine derivatives, pharmaceutical compositions containing the same, and a process for the preparation of the same
HU9802995A3 (en) Substituted sulphonylamino (thio)carbonyl derivatives, intermediates, thereof herbicide compositions containing these compounds as active ingredients, process for the preparation and use of the compounds and compositions
WO2002072567A3 (en) Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them
WO1999058527A3 (en) Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
CA2137748A1 (en) Amidinophenylalanine derivatives, a process for their preparation, their use and compositions containing these as anticoagulants
HUT53880A (en) Process for preparation of 3-phenyl-5,6-dilhydrobenz (c)-acridine-carboxylic-acids and carboxylic-acid derivatives and for manufacturing of pharmaceutical composition containing these compounds as active ingredient
WO2001029066A3 (en) Basic monocyclic compounds having nk2 antagonist action, processes for their preparation, and formulations containing them
HU895241D0 (en) Process for the preparation of substituted 1,3,5-triazin-trione derivatives and pharmaceutical compositions containing said compounds as active ingredient
YU72802A (en) Pharmaceutical compositions containing oligosaccharides and preparation thereof
AU5525199A (en) N-hydroxyacylamino compounds, process for their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM HR ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM HR ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWE Wipo information: entry into national phase

Ref document number: P20000750A

Country of ref document: HR

WWE Wipo information: entry into national phase

Ref document number: 17212000

Country of ref document: SK

Ref document number: 40529/99

Country of ref document: AU

Ref document number: PV2000-4218

Country of ref document: CZ

ENP Entry into the national phase

Ref document number: 17212000

Country of ref document: SK

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 1020007012773

Country of ref document: KR

ENP Entry into the national phase

Ref document number: 2332275

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 1999923772

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 09700345

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 1999923772

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: PV2000-4218

Country of ref document: CZ

WWP Wipo information: published in national office

Ref document number: 1020007012773

Country of ref document: KR

WWG Wipo information: grant in national office

Ref document number: 40529/99

Country of ref document: AU

WWW Wipo information: withdrawn in national office

Ref document number: 1999923772

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1020007012773

Country of ref document: KR

WWR Wipo information: refused in national office

Ref document number: PV2000-4218

Country of ref document: CZ