WO1999058527A3 - Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient - Google Patents

Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient Download PDF

Info

Publication number
WO1999058527A3
WO1999058527A3 PCT/HU1999/000038 HU9900038W WO9958527A3 WO 1999058527 A3 WO1999058527 A3 WO 1999058527A3 HU 9900038 W HU9900038 W HU 9900038W WO 9958527 A3 WO9958527 A3 WO 9958527A3
Authority
WO
WIPO (PCT)
Prior art keywords
process
preparation
pharmaceutical composition
active ingredient
same
Prior art date
Application number
PCT/HU1999/000038
Other languages
French (fr)
Other versions
WO1999058527A2 (en
Inventor
Bela Agai
Andras Egyed
Istvan Gacsalyi
Istvan Gyertyan
Megyeri Katalin Ivanicsne
Szabolcs Kertesz
Gyoergy Levay
Kovacs Aniko Miklosne
Zoltan Tamas Nagy
Gyoenoes Ildiko Nagyne
Levente Ondi
Katalin Pallagi
Jozsef Reiter
Endre Rivo
Eva Schmidt
Gyula Simig
Tamas Szabados
Gabor Szenasi
Original Assignee
Bela Agai
Andras Egyed
Egyt Gyogyszervegyeszeti Gyar
Istvan Gacsalyi
Istvan Gyertyan
Megyeri Katalin Ivanicsne
Szabolcs Kertesz
Gyoergy Levay
Kovacs Aniko Miklosne
Zoltan Tamas Nagy
Gyoenoes Ildiko Nagyne
Levente Ondi
Katalin Pallagi
Jozsef Reiter
Endre Rivo
Eva Schmidt
Gyula Simig
Tamas Szabados
Gabor Szenasi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to HUP9801085 priority Critical
Priority to HUP9801086 priority
Priority to HU9801085A priority patent/HU9801085A3/en
Priority to HU9801086A priority patent/HU9801086A3/en
Application filed by Bela Agai, Andras Egyed, Egyt Gyogyszervegyeszeti Gyar, Istvan Gacsalyi, Istvan Gyertyan, Megyeri Katalin Ivanicsne, Szabolcs Kertesz, Gyoergy Levay, Kovacs Aniko Miklosne, Zoltan Tamas Nagy, Gyoenoes Ildiko Nagyne, Levente Ondi, Katalin Pallagi, Jozsef Reiter, Endre Rivo, Eva Schmidt, Gyula Simig, Tamas Szabados, Gabor Szenasi filed Critical Bela Agai
Publication of WO1999058527A2 publication Critical patent/WO1999058527A2/en
Publication of WO1999058527A3 publication Critical patent/WO1999058527A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Abstract

The invention refers to novel benzofuran derivatives of formula (I), a process for preparing these compounds and to pharmaceutical compositions containing these active substances.
PCT/HU1999/000038 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient WO1999058527A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
HUP9801085 1998-05-14
HUP9801086 1998-05-14
HU9801085A HU9801085A3 (en) 1998-05-14 1998-05-14 Piperazinyl-alkyl-benzofurane derivatives, pharmaceutical compositions containing them as active ingredient and process for producing the active ingredient
HU9801086A HU9801086A3 (en) 1998-05-14 1998-05-14 Benzofurane derivatives, pharmaceutical compositions containing them as active ingredient process for producing the active ingredient and intermediates of them

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
EP99923772A EP1077973A2 (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
JP2000548331A JP2002514643A (en) 1998-05-14 1999-05-13 A benzofuran derivative, a pharmaceutical composition containing the same and a method for producing the active ingredient thereof.
AU40529/99A AU753706B2 (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
SK1721-2000A SK17212000A3 (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
CA002332275A CA2332275A1 (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
PL99345309A PL345309A1 (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
KR1020007012773A KR20010043618A (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient
HR20000750A HRP20000750A2 (en) 1998-05-14 2000-11-03 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US70034500A A-371-Of-International 2000-12-27 2000-12-27
US10/736,714 Division US20040186170A1 (en) 1998-05-14 2003-12-15 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient

Publications (2)

Publication Number Publication Date
WO1999058527A2 WO1999058527A2 (en) 1999-11-18
WO1999058527A3 true WO1999058527A3 (en) 2000-01-27

Family

ID=26318308

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/HU1999/000038 WO1999058527A2 (en) 1998-05-14 1999-05-13 Benzofuran derivatives, pharmaceutical composition containing the same, and a process for the preparation of the active ingredient

Country Status (9)

Country Link
EP (1) EP1077973A2 (en)
JP (1) JP2002514643A (en)
KR (1) KR20010043618A (en)
AU (1) AU753706B2 (en)
CA (1) CA2332275A1 (en)
HR (1) HRP20000750A2 (en)
PL (1) PL345309A1 (en)
SK (1) SK17212000A3 (en)
WO (1) WO1999058527A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2049601A (en) 1999-12-20 2001-07-03 Eli Lilly And Company Benzofuran derivatives
EP1248786A1 (en) 1999-12-20 2002-10-16 Eli Lilly And Company Benzofuran derivatives
FR2845992B1 (en) * 2002-10-16 2005-02-04 Pf Medicament 3- (cyclopenten-1yl) -benzyl-ou3- (cyclopenten-1yl) -heteroarylmethyl-amine derivatives and their use as medicaments for the treatment of schizophrenia
US20080319209A1 (en) * 2005-02-17 2008-12-25 Guozhi Wang Process for Preparing (Disubstitutedpropenyl) Phenylalkyl Substituted Dihydrobenzofurans
HU230729B1 (en) * 2007-05-30 2017-12-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag New benzofuran derivatives as selective inhibitors of 5-ht7 and process for their preparation
HU230761B1 (en) * 2007-05-30 2018-03-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag New benzofuran derivatives as selective inhibitors of 5-ht6 and process for their preparation
GB201312499D0 (en) * 2013-07-12 2013-08-28 Isis Innovation Therapeutic compounds

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH474511A (en) * 1966-06-24 1969-06-30 F. Hoffmann-La Roche & Co. Aktiengesellschaft
DE2235597A1 (en) * 1972-07-20 1974-01-31 Boehringer Mannheim Gmbh clamp-1-on-shaped 3- (5,6,7,8tetrahydronaphth-1-yl-oxy) -propyl bracket derivatives piperazine and to processes for their preparation
DE2724083A1 (en) * 1976-05-31 1978-02-23 Parcor Benzo (b) furan derivatives, processes for their preparation and the same medium containing
US4110536A (en) * 1977-04-18 1978-08-29 Miles Laboratories, Inc. Derivatives of 5-(indol-3-yl)hydantoin
WO1986002550A1 (en) * 1984-10-23 1986-05-09 Rorer International (Overseas) Inc. Bicyclic benzo-oxy heterocyclic ethers and thioethers as h2-receptors antagonists
GB2221680A (en) * 1988-08-12 1990-02-14 Merck & Co Inc Novel 5-hydroxy-2,3-dihydrobenzorfurans as inhibitors of leukotriene bio- synthesis
EP0445862A2 (en) * 1990-03-06 1991-09-11 Janssen Pharmaceutica N.V. N-(4-piperidinyl)(dihydrobenzofuran or dihydro-2H-benzopyran)carboxamide derivatives
FR2681319A1 (en) * 1991-09-12 1993-03-19 Synthelabo 1-(Phenoxyalkyl)piperidine derivatives, their preparation and their application in therapeutics
WO1996010027A1 (en) * 1994-09-27 1996-04-04 Janssen Pharmaceutica N.V. N-substituted piperidinyl bicyclic benzoate derivatives
WO1996016060A1 (en) * 1994-11-24 1996-05-30 Janssen Pharmaceutica N.V. Enterokinetic benzamide
WO1996033186A1 (en) * 1995-04-18 1996-10-24 Pharmacia & Upjohn S.P.A. Substituted dihydrobenzofuran derivatives as 5-ht4 agonists
WO1997023216A1 (en) * 1995-12-22 1997-07-03 Warner-Lambert Company 4-substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
WO1997030031A1 (en) * 1996-02-15 1997-08-21 Janssen Pharmaceutica N.V. Esters of 3-hydroxy-piperidinemethanol derivatives

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH474511A (en) * 1966-06-24 1969-06-30 F. Hoffmann-La Roche & Co. Aktiengesellschaft
DE2235597A1 (en) * 1972-07-20 1974-01-31 Boehringer Mannheim Gmbh clamp-1-on-shaped 3- (5,6,7,8tetrahydronaphth-1-yl-oxy) -propyl bracket derivatives piperazine and to processes for their preparation
DE2724083A1 (en) * 1976-05-31 1978-02-23 Parcor Benzo (b) furan derivatives, processes for their preparation and the same medium containing
US4110536A (en) * 1977-04-18 1978-08-29 Miles Laboratories, Inc. Derivatives of 5-(indol-3-yl)hydantoin
WO1986002550A1 (en) * 1984-10-23 1986-05-09 Rorer International (Overseas) Inc. Bicyclic benzo-oxy heterocyclic ethers and thioethers as h2-receptors antagonists
GB2221680A (en) * 1988-08-12 1990-02-14 Merck & Co Inc Novel 5-hydroxy-2,3-dihydrobenzorfurans as inhibitors of leukotriene bio- synthesis
EP0445862A2 (en) * 1990-03-06 1991-09-11 Janssen Pharmaceutica N.V. N-(4-piperidinyl)(dihydrobenzofuran or dihydro-2H-benzopyran)carboxamide derivatives
FR2681319A1 (en) * 1991-09-12 1993-03-19 Synthelabo 1-(Phenoxyalkyl)piperidine derivatives, their preparation and their application in therapeutics
WO1996010027A1 (en) * 1994-09-27 1996-04-04 Janssen Pharmaceutica N.V. N-substituted piperidinyl bicyclic benzoate derivatives
WO1996016060A1 (en) * 1994-11-24 1996-05-30 Janssen Pharmaceutica N.V. Enterokinetic benzamide
WO1996033186A1 (en) * 1995-04-18 1996-10-24 Pharmacia & Upjohn S.P.A. Substituted dihydrobenzofuran derivatives as 5-ht4 agonists
WO1997023216A1 (en) * 1995-12-22 1997-07-03 Warner-Lambert Company 4-substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
WO1997030031A1 (en) * 1996-02-15 1997-08-21 Janssen Pharmaceutica N.V. Esters of 3-hydroxy-piperidinemethanol derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J. B. HANSEN ET AL., EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 32, no. 2, 1997, pages 103 - 111, XP004054789 *

Also Published As

Publication number Publication date
CA2332275A1 (en) 1999-11-18
WO1999058527A2 (en) 1999-11-18
HRP20000750A2 (en) 2001-06-30
JP2002514643A (en) 2002-05-21
SK17212000A3 (en) 2001-05-10
KR20010043618A (en) 2001-05-25
AU753706B2 (en) 2002-10-24
PL345309A1 (en) 2001-12-03
EP1077973A2 (en) 2001-02-28
AU4052999A (en) 1999-11-29

Similar Documents

Publication Publication Date Title
DK0807111T3 (en) Substituted heterocyclic compounds, processes for their preparation and pharmaceutical compositions containing them
DK1077927T3 (en) New Substituted Cyclic Compounds, Methods of Preparation thereof, and Pharmaceutical Compositions Containing These
DK1044970T3 (en) Aminotriazole Compounds, Processes for their Preparation and Pharmaceutical Compositions Containing These
AU1457395A (en) Novel optionally substituted phenylimidazolidines, intermediates and process for their preparation, their use as drugs and pharmaceutical compositions containing them
IE62371B1 (en) R-enantiomers of n-propargyl-1-aminoindan compounds, their preparation and pharmaceutical compositions containing them.
HK1055973A1 (en) Glucopyranosyloxy benzylbenzene derivatives, medicinal composition containing the same and intermediates for the preparation of the derivatives.
AU1286001A (en) Pyrazolecarboxylic acid tricyclic derivatives, preparation and pharmaceutical compositions containing same
HU0003844A3 (en) Novel spiroazabicyclic heterocyclic compounds, process for their preparation, their use and pharmaceutical compositions containing them
PT95826A (en) Process for the preparation of pharmaceutical compositions containing as active ingredient r-alpha-liponic acid or s-alpha-liponic acid
AU2095092A (en) New arylethylamine compounds, processes for the preparation thereof, and pharmaceutical compositions containing them
HK1046134A1 (en) Novel lipoic acid derivatives, their preparation, and pharmaceutical compositions containing them.
CA2183972A1 (en) Oxazolidinone derivatives and pharmaceutical compositions containing them
GB2210879B (en) 4h-1-benzopyran-4-one derivative or its salt, process for producing the same and pharmaceutical composition comprising the same as active ingredient
CA2129288A1 (en) Phosphonooxymethyl Esters of Taxane Derivatives
BG103795A (en) Pharmaceutical compositions with appetite suppressing activity
BR0214142A (en) N-Adamantyl methyl derivatives and intermediates as pharmaceutical compositions and processes for their preparation
CA2414095A1 (en) Novel compounds
AU2001253287A1 (en) Stable pharmaceutical compositions containing 7-substituted-3,5-dihydroxyheptanoic acids or 7-substituted-3,5-dihydroxyheptenoic acids
IL160042A (en) Pyrroles having hypolipidemic and hypocholesteremic activity, pharmaceutical compositions comprising said pyrroles, use of said pyrroles in the preparation of medicaments and a process for the preparation of said pyrroles
RU2002107975A (en) Glucopyananosyloxypyrazolic derivatives, medicinal compositions containing these derivatives, and intermediate compounds for their production
HU9603494A3 (en) Hydroxycarboxamide derivatives, pharmaceutical compositions containing them, process for the preparation thereof
MXPA02012904A (en) Novel $g(y) crystalline form of perindopril tert-butylamine salt, preparation method, and pharmaceutical compositions containing same.
CA2351709A1 (en) Novel triazolo(4,5-d)pyrimidine compounds
HU0200190A3 (en) Dimeric compounds and as inhibitors of neuraminidase, process for their preparation and pharmaceutical compositions containing them
MY120842A (en) 1,4-benzothiazepine-1, 1-dioxide derivatives substituted by sugar residues, process for their preparation, pharmaceuticals comprising these compounds, and their use.

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM HR ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM HR ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWE Wipo information: entry into national phase

Ref document number: P20000750A

Country of ref document: HR

WWE Wipo information: entry into national phase

Ref document number: 17212000

Country of ref document: SK

Ref document number: 40529/99

Country of ref document: AU

Ref document number: PV2000-4218

Country of ref document: CZ

ENP Entry into the national phase in:

Ref document number: 17212000

Country of ref document: SK

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 1020007012773

Country of ref document: KR

ENP Entry into the national phase in:

Ref document number: 2332275

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 1999923772

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 09700345

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 1999923772

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: PV2000-4218

Country of ref document: CZ

WWP Wipo information: published in national office

Ref document number: 1020007012773

Country of ref document: KR

WWG Wipo information: grant in national office

Ref document number: 40529/99

Country of ref document: AU

WWW Wipo information: withdrawn in national office

Ref document number: 1999923772

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1020007012773

Country of ref document: KR

WWR Wipo information: refused in national office

Ref document number: PV2000-4218

Country of ref document: CZ