PL3389679T3 - Sposób liofilizacji próbki mikroflory kałowej - Google Patents

Sposób liofilizacji próbki mikroflory kałowej

Info

Publication number
PL3389679T3
PL3389679T3 PL16826115T PL16826115T PL3389679T3 PL 3389679 T3 PL3389679 T3 PL 3389679T3 PL 16826115 T PL16826115 T PL 16826115T PL 16826115 T PL16826115 T PL 16826115T PL 3389679 T3 PL3389679 T3 PL 3389679T3
Authority
PL
Poland
Prior art keywords
lyophilisation
sample
fecal microbiota
microbiota
fecal
Prior art date
Application number
PL16826115T
Other languages
English (en)
Inventor
Hervé AFFAGARD
Carole SCHWINTNER
Catherine JUSTE
Joël DORE
Audrey CHAPRON
Fernanda Fonseca
Olivier David
Original Assignee
Maat Pharma
Institut National De La Recherche Agronomique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maat Pharma, Institut National De La Recherche Agronomique filed Critical Maat Pharma
Publication of PL3389679T3 publication Critical patent/PL3389679T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL16826115T 2015-12-18 2016-12-19 Sposób liofilizacji próbki mikroflory kałowej PL3389679T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1562750A FR3045383B1 (fr) 2015-12-18 2015-12-18 Procede de lyophilisation d'un echantillon de microbiote fecal
PCT/FR2016/053550 WO2017103550A1 (fr) 2015-12-18 2016-12-19 Procede de lyophilisation d'un echantillon de microbiote fecal
EP16826115.4A EP3389679B1 (fr) 2015-12-18 2016-12-19 Procede de lyophilisation d'un echantillon de microbiote fecal

Publications (1)

Publication Number Publication Date
PL3389679T3 true PL3389679T3 (pl) 2020-09-07

Family

ID=55300683

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16826115T PL3389679T3 (pl) 2015-12-18 2016-12-19 Sposób liofilizacji próbki mikroflory kałowej

Country Status (15)

Country Link
US (1) US10736849B2 (pl)
EP (1) EP3389679B1 (pl)
JP (1) JP6948321B2 (pl)
KR (1) KR102341203B1 (pl)
CN (1) CN108430481B (pl)
AU (1) AU2016370600B2 (pl)
CA (1) CA3007289C (pl)
DK (1) DK3389679T3 (pl)
ES (1) ES2777624T3 (pl)
FR (1) FR3045383B1 (pl)
HU (1) HUE048991T2 (pl)
IL (1) IL259888B (pl)
PL (1) PL3389679T3 (pl)
PT (1) PT3389679T (pl)
WO (1) WO2017103550A1 (pl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3485879A1 (en) 2017-11-17 2019-05-22 Maat Pharma Pharmaceutical oral formulation comrpsing bacteria
WO2019149266A1 (en) * 2018-02-02 2019-08-08 The Chinese University Of Hong Kong Fecal fungome and therapeutic efficacy of fecal microbiota transplantation
WO2019165285A1 (en) * 2018-02-23 2019-08-29 Crestovo Holdings Llc Microbiome related immunotherapies
NL2021365B1 (en) * 2018-07-20 2020-01-29 Acad Medisch Ct Fecal matter for prevention or treatment of autoimmune diseases
JP7175990B2 (ja) 2018-03-02 2022-11-21 アカデミッシュ メディッシュ セントラム 自己免疫疾患の予防または処置のための糞便物質
EP3597202A1 (en) 2018-07-20 2020-01-22 Maat Pharma Fecal microbiota composition, for use in reducing treatment-induced inflammation
CN110540941A (zh) * 2019-07-16 2019-12-06 上海交通大学 一种从粪便中提取保存菌液的方法
ES2803099B2 (es) * 2019-07-22 2021-11-08 Moehs Iberica Sl Procedimiento de obtención de besilato de remimazolam amorfo
FR3103827B1 (fr) * 2019-12-02 2025-04-25 Genialis Procede de lyophilisation d’une composition cellulaire cryogenisee et contenant du gaz dissous
EP3895716A1 (en) 2020-04-17 2021-10-20 Maat Pharma Fmt performance prediction test to guide and optimize therapeutic management of gvhd patients
JP2024501818A (ja) 2020-12-23 2024-01-16 マー ファルマ 微生物の複合群集を増殖させる方法
EP4086337A1 (en) 2021-05-06 2022-11-09 Maat Pharma Method of predicting and then producing a mix of microbiota samples
DE102022111013B4 (de) 2022-05-04 2025-04-30 Labor LS SE & Co. KG Verfahren zur Extraktion und Konservierung von Mikroorganismen aus einer Stuhlprobe eines Lebewesens
EP4369344A1 (en) 2022-11-08 2024-05-15 Maat Pharma Determination of microbiota samples to produce a target mix product and prediction of mixes
CN116046960A (zh) * 2022-12-30 2023-05-02 上海采微生物科技有限公司 粪便脂肪酸样品保存液以及粪便脂肪酸样品预处理的方法
EP4606380A1 (en) 2024-02-22 2025-08-27 Microviable Therapeutics SL Method for fecal microbiome purification and uses thereof
CN120210328B (zh) * 2025-05-28 2025-09-12 中国大熊猫保护研究中心 一种用于大熊猫粪便dna提取的预处理方法及应用

Family Cites Families (28)

* Cited by examiner, † Cited by third party
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AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
KR20100088894A (ko) * 2009-02-02 2010-08-11 에이엠바이오 (주) 멤브레인 생물반응기를 이용한 고농도 유산균의 생산방법 및 유산균 동결건조 분말의 제조방법
DK2419114T4 (da) * 2009-05-01 2019-05-27 Uas Laboratories Llc Bakteriesammensætninger til profylakse og behandling af degenerative sygdomme
EP2552321B1 (en) 2010-04-02 2014-03-12 Antonius Henricus Petrus Bosch Auxiliary device for receiving fecal matter
CA2807242C (en) 2010-08-04 2017-05-02 Thomas Julius Borody Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
WO2014152484A1 (en) * 2013-03-14 2014-09-25 Regents Of The University Of Minnesota Freeze dried fecal microbiota for use in fecal microbial transplantation
BR112013022927A2 (pt) 2011-03-09 2016-12-06 Univ Minnesota composição, métodos para substituir ou suplementar ou modificar uma microbiota do cólon de um sujeito, e para tratar um sujeito, e, uso de uma composição
DK2750682T3 (en) 2011-10-11 2016-08-22 Achim Biotherapeutics Ab A composition comprising anaerobically cultured human intestinal flora
CN104918624A (zh) * 2012-11-26 2015-09-16 托马斯·朱利叶斯·波洛迪 恢复排泄物微生物群的组合物及其制造和使用方法
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HK1253064A1 (zh) 2015-06-01 2019-06-06 The University Of Chicago 通过操纵共生微生物菌群对癌症的治疗
PL3307289T3 (pl) 2015-06-09 2022-01-17 Rebiotix, Inc. Sposoby wytwarzania kompozycji do terapii przywracającej mikrobiotę (mrt)
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
HUP1500332A2 (en) 2015-07-16 2017-01-30 Feher Janos Dr Compositions for maintaining and restoring microbiota-host symbiosis
EP3368050A1 (en) 2015-10-26 2018-09-05 Crestovo Holdings LLC Compositions and methods for fecal microbiota-related therapy
FR3045384B1 (fr) * 2015-12-18 2020-02-07 Institut National De La Recherche Agronomique Composition lyophilisee pour la conservation de microbiote dans son ecosysteme
US20180000872A1 (en) 2016-07-01 2018-01-04 Regents Of The University Of Minnesota Compositions and methods for c. difficile treatment
US20180036352A1 (en) 2016-08-03 2018-02-08 Crestovo Holdings Llc Methods for treating ulcerative colitis

Also Published As

Publication number Publication date
US10736849B2 (en) 2020-08-11
IL259888B (en) 2020-08-31
AU2016370600B2 (en) 2021-07-15
EP3389679B1 (fr) 2020-02-12
AU2016370600A1 (en) 2018-06-28
JP6948321B2 (ja) 2021-10-13
KR20180086506A (ko) 2018-07-31
ES2777624T3 (es) 2020-08-05
JP2019501156A (ja) 2019-01-17
US20180369147A1 (en) 2018-12-27
CN108430481A (zh) 2018-08-21
DK3389679T3 (da) 2020-03-16
CA3007289A1 (fr) 2017-06-22
CA3007289C (fr) 2022-05-03
PT3389679T (pt) 2020-04-21
HUE048991T2 (hu) 2020-09-28
KR102341203B1 (ko) 2021-12-20
WO2017103550A1 (fr) 2017-06-22
IL259888A (en) 2018-07-31
CN108430481B (zh) 2021-12-28
FR3045383B1 (fr) 2019-06-14
EP3389679A1 (fr) 2018-10-24
FR3045383A1 (fr) 2017-06-23

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