DK3389679T3 - Fremgangsmåde til lyofilisering af en prøve af fækal mikrobiota - Google Patents
Fremgangsmåde til lyofilisering af en prøve af fækal mikrobiota Download PDFInfo
- Publication number
- DK3389679T3 DK3389679T3 DK16826115.4T DK16826115T DK3389679T3 DK 3389679 T3 DK3389679 T3 DK 3389679T3 DK 16826115 T DK16826115 T DK 16826115T DK 3389679 T3 DK3389679 T3 DK 3389679T3
- Authority
- DK
- Denmark
- Prior art keywords
- lyophilizing
- sample
- fecal microbiota
- microbiota
- fecal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/04—Preserving or maintaining viable microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
- A61K2035/115—Probiotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Developmental Biology & Embryology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1562750A FR3045383B1 (fr) | 2015-12-18 | 2015-12-18 | Procede de lyophilisation d'un echantillon de microbiote fecal |
| PCT/FR2016/053550 WO2017103550A1 (fr) | 2015-12-18 | 2016-12-19 | Procede de lyophilisation d'un echantillon de microbiote fecal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3389679T3 true DK3389679T3 (da) | 2020-03-16 |
Family
ID=55300683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16826115.4T DK3389679T3 (da) | 2015-12-18 | 2016-12-19 | Fremgangsmåde til lyofilisering af en prøve af fækal mikrobiota |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US10736849B2 (da) |
| EP (1) | EP3389679B1 (da) |
| JP (1) | JP6948321B2 (da) |
| KR (1) | KR102341203B1 (da) |
| CN (1) | CN108430481B (da) |
| AU (1) | AU2016370600B2 (da) |
| CA (1) | CA3007289C (da) |
| DK (1) | DK3389679T3 (da) |
| ES (1) | ES2777624T3 (da) |
| FR (1) | FR3045383B1 (da) |
| HU (1) | HUE048991T2 (da) |
| IL (1) | IL259888B (da) |
| PL (1) | PL3389679T3 (da) |
| PT (1) | PT3389679T (da) |
| WO (1) | WO2017103550A1 (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3485879A1 (en) | 2017-11-17 | 2019-05-22 | Maat Pharma | Pharmaceutical oral formulation comrpsing bacteria |
| GB2585291B (en) * | 2018-02-02 | 2023-07-19 | Univ Hong Kong Chinese | Fecal fungome and therapeutic efficacy of fecal microbiota transplantation |
| CN112203669A (zh) | 2018-02-23 | 2021-01-08 | 克雷斯顿沃控股公司 | 微生物组相关的免疫疗法 |
| KR20200128126A (ko) * | 2018-03-02 | 2020-11-11 | 아카데미쉬 메디쉬 센트럼 | 자가 면역 질환의 예방 또는 치료를 위한 대변 |
| NL2021365B1 (en) * | 2018-07-20 | 2020-01-29 | Acad Medisch Ct | Fecal matter for prevention or treatment of autoimmune diseases |
| EP3597202A1 (en) | 2018-07-20 | 2020-01-22 | Maat Pharma | Fecal microbiota composition, for use in reducing treatment-induced inflammation |
| CN110540941A (zh) * | 2019-07-16 | 2019-12-06 | 上海交通大学 | 一种从粪便中提取保存菌液的方法 |
| ES2803099B2 (es) * | 2019-07-22 | 2021-11-08 | Moehs Iberica Sl | Procedimiento de obtención de besilato de remimazolam amorfo |
| FR3103827B1 (fr) * | 2019-12-02 | 2025-04-25 | Genialis | Procede de lyophilisation d’une composition cellulaire cryogenisee et contenant du gaz dissous |
| EP3895716A1 (en) | 2020-04-17 | 2021-10-20 | Maat Pharma | Fmt performance prediction test to guide and optimize therapeutic management of gvhd patients |
| AU2021405816A1 (en) | 2020-12-23 | 2023-07-06 | Institut National De Recherche Pour L'agriculture, L'alimentation Et L'environnement | Method of expanding a complex community of microorganisms |
| EP4086337A1 (en) | 2021-05-06 | 2022-11-09 | Maat Pharma | Method of predicting and then producing a mix of microbiota samples |
| DE102022111013B4 (de) | 2022-05-04 | 2025-04-30 | Labor LS SE & Co. KG | Verfahren zur Extraktion und Konservierung von Mikroorganismen aus einer Stuhlprobe eines Lebewesens |
| EP4369344A1 (en) | 2022-11-08 | 2024-05-15 | Maat Pharma | Determination of microbiota samples to produce a target mix product and prediction of mixes |
| CN116046960A (zh) * | 2022-12-30 | 2023-05-02 | 上海采微生物科技有限公司 | 粪便脂肪酸样品保存液以及粪便脂肪酸样品预处理的方法 |
| EP4606380A1 (en) | 2024-02-22 | 2025-08-27 | Microviable Therapeutics SL | Method for fecal microbiome purification and uses thereof |
| CN120210328B (zh) * | 2025-05-28 | 2025-09-12 | 中国大熊猫保护研究中心 | 一种用于大熊猫粪便dna提取的预处理方法及应用 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| KR20100088894A (ko) * | 2009-02-02 | 2010-08-11 | 에이엠바이오 (주) | 멤브레인 생물반응기를 이용한 고농도 유산균의 생산방법 및 유산균 동결건조 분말의 제조방법 |
| CN102481322A (zh) * | 2009-05-01 | 2012-05-30 | 微制药有限公司 | 预防和治疗退化性疾病的细菌组合物 |
| EP2552321B1 (en) | 2010-04-02 | 2014-03-12 | Antonius Henricus Petrus Bosch | Auxiliary device for receiving fecal matter |
| NZ607043A (en) | 2010-08-04 | 2015-05-29 | Borody Thomas J | Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them |
| CA2829385C (en) * | 2011-03-09 | 2021-07-13 | Michael J. Sadowsky | Compositions and methods for transplantation of colon microbiota |
| WO2014152484A1 (en) * | 2013-03-14 | 2014-09-25 | Regents Of The University Of Minnesota | Freeze dried fecal microbiota for use in fecal microbial transplantation |
| EP2750682B1 (en) | 2011-10-11 | 2016-05-18 | Achim Biotherapeutics AB | Composition comprising anaerobically cultivated human intestinal microbiota |
| AU2013350328A1 (en) | 2012-11-26 | 2015-07-09 | Thomas Julius Borody | Compositions for the restoration of a fecal microbiota and methods for making and using them |
| WO2014121304A1 (en) | 2013-02-04 | 2014-08-07 | Seres Health, Inc. | Compositions and methods |
| AU2014212004B2 (en) | 2013-02-04 | 2018-09-20 | Société des Produits Nestlé S.A. | Compositions for treating or preventing or reducing the severity of clostridium difficile related diseases |
| AU2014262125B2 (en) | 2013-04-30 | 2020-02-13 | Thomas Julius Borody | Compositions and methods for treating microbiota-related psychotropic conditions and diseases |
| JP6330032B2 (ja) | 2013-06-05 | 2018-05-23 | レビオティクス インコーポレイテッドＲｅｂｉｏｔｉｘ，Ｉｎｃ． | 微生物叢回復療法組成物を製造、処理、および梱包するための方法 |
| US10383901B2 (en) | 2013-06-05 | 2019-08-20 | Rebiotix, Inc. | Microbiota restoration therapy (MRT), compositions and methods of manufacture |
| US9511099B2 (en) * | 2013-06-05 | 2016-12-06 | Rebiotix, Inc. | Microbiota restoration therapy (MRT), compositions and methods of manufacture |
| US9782445B2 (en) | 2013-06-05 | 2017-10-10 | Rebiotix, Inc. | Microbiota restoration therapy (MRT), compositions and methods of manufacture |
| US9694039B2 (en) | 2013-06-05 | 2017-07-04 | Rebiotix, Inc. | Microbiota restoration therapy (MRT), compositions and methods of manufacture |
| US9511100B2 (en) | 2013-06-05 | 2016-12-06 | Rebiotix, Inc. | Microbiota restoration therapy (MRT), compositions and methods of manufacture |
| US20150037285A1 (en) * | 2013-07-03 | 2015-02-05 | New York University | Methods for efficient transfer of viable and bioactive microbiota |
| BR112017024264B1 (pt) | 2015-05-14 | 2022-07-12 | Crestovo Holdings Llc | Composições para transplante de flora fecal e métodos de preparação e utilização das mesmas, e dispositivos para sua administração |
| KR102661603B1 (ko) | 2015-06-01 | 2024-04-29 | 더 유니버서티 오브 시카고 | 공생 미생물총의 조작에 의한 암의 치료 |
| US10905726B2 (en) | 2015-06-09 | 2021-02-02 | Rebiotix, Inc. | Microbiota restoration therapy (MRT) compositions and methods of manufacture |
| CN107921072A (zh) | 2015-06-09 | 2018-04-17 | 雷柏奥提斯有限公司 | 微生物群恢复治疗（mrt）组合物和制造方法 |
| HUP1500332A2 (en) | 2015-07-16 | 2017-01-30 | Feher Janos Dr | Compositions for maintaining and restoring microbiota-host symbiosis |
| CA3003138A1 (en) | 2015-10-26 | 2017-05-04 | Crestovo Holdings Llc | Compositions and methods for fecal microbiota-related therapy |
| FR3045384B1 (fr) * | 2015-12-18 | 2020-02-07 | Institut National De La Recherche Agronomique | Composition lyophilisee pour la conservation de microbiote dans son ecosysteme |
| US20180000872A1 (en) | 2016-07-01 | 2018-01-04 | Regents Of The University Of Minnesota | Compositions and methods for c. difficile treatment |
| US20180036352A1 (en) | 2016-08-03 | 2018-02-08 | Crestovo Holdings Llc | Methods for treating ulcerative colitis |
-
2015
- 2015-12-18 FR FR1562750A patent/FR3045383B1/fr not_active Expired - Fee Related
-
2016
- 2016-12-19 AU AU2016370600A patent/AU2016370600B2/en active Active
- 2016-12-19 CA CA3007289A patent/CA3007289C/fr active Active
- 2016-12-19 WO PCT/FR2016/053550 patent/WO2017103550A1/fr not_active Ceased
- 2016-12-19 US US16/063,419 patent/US10736849B2/en active Active
- 2016-12-19 PT PT168261154T patent/PT3389679T/pt unknown
- 2016-12-19 ES ES16826115T patent/ES2777624T3/es active Active
- 2016-12-19 EP EP16826115.4A patent/EP3389679B1/fr active Active
- 2016-12-19 KR KR1020187020068A patent/KR102341203B1/ko active Active
- 2016-12-19 CN CN201680073680.7A patent/CN108430481B/zh active Active
- 2016-12-19 JP JP2018531198A patent/JP6948321B2/ja active Active
- 2016-12-19 DK DK16826115.4T patent/DK3389679T3/da active
- 2016-12-19 PL PL16826115T patent/PL3389679T3/pl unknown
- 2016-12-19 HU HUE16826115A patent/HUE048991T2/hu unknown
-
2018
- 2018-06-07 IL IL259888A patent/IL259888B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| IL259888B (en) | 2020-08-31 |
| CN108430481B (zh) | 2021-12-28 |
| PL3389679T3 (pl) | 2020-09-07 |
| CA3007289A1 (fr) | 2017-06-22 |
| CA3007289C (fr) | 2022-05-03 |
| HUE048991T2 (hu) | 2020-09-28 |
| FR3045383B1 (fr) | 2019-06-14 |
| AU2016370600B2 (en) | 2021-07-15 |
| JP2019501156A (ja) | 2019-01-17 |
| ES2777624T3 (es) | 2020-08-05 |
| IL259888A (en) | 2018-07-31 |
| AU2016370600A1 (en) | 2018-06-28 |
| WO2017103550A1 (fr) | 2017-06-22 |
| FR3045383A1 (fr) | 2017-06-23 |
| US20180369147A1 (en) | 2018-12-27 |
| KR20180086506A (ko) | 2018-07-31 |
| CN108430481A (zh) | 2018-08-21 |
| US10736849B2 (en) | 2020-08-11 |
| EP3389679A1 (fr) | 2018-10-24 |
| PT3389679T (pt) | 2020-04-21 |
| EP3389679B1 (fr) | 2020-02-12 |
| KR102341203B1 (ko) | 2021-12-20 |
| JP6948321B2 (ja) | 2021-10-13 |
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