DK3285784T3 - Fremgangsmåde til fremstilling af en prøve af fækal mikrobiota - Google Patents

Fremgangsmåde til fremstilling af en prøve af fækal mikrobiota Download PDF

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Publication number
DK3285784T3
DK3285784T3 DK16723433.5T DK16723433T DK3285784T3 DK 3285784 T3 DK3285784 T3 DK 3285784T3 DK 16723433 T DK16723433 T DK 16723433T DK 3285784 T3 DK3285784 T3 DK 3285784T3
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DK
Denmark
Prior art keywords
preparing
sample
fecal microbiota
microbiota
fecal
Prior art date
Application number
DK16723433.5T
Other languages
English (en)
Inventor
Hervé Affagard
Carole Schwintner
Patricia Lepage
Christel Maillet
Sylvie Rabot
Fernanda Fonseca
Hervé Blottiere
Joël Dore
Catherine Juste
Original Assignee
Maat Pharma
Institut National De Rech Pour L'agriculture L'alimentation Et L'environnement
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Maat Pharma, Institut National De Rech Pour L'agriculture L'alimentation Et L'environnement filed Critical Maat Pharma
Application granted granted Critical
Publication of DK3285784T3 publication Critical patent/DK3285784T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/38—Stomach; Intestine; Goblet cells; Oral mucosa; Saliva
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0278—Physical preservation processes
    • A01N1/0284—Temperature processes, i.e. using a designated change in temperature over time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Physiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
DK16723433.5T 2015-04-24 2016-04-22 Fremgangsmåde til fremstilling af en prøve af fækal mikrobiota DK3285784T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1553716A FR3035328B1 (fr) 2015-04-24 2015-04-24 Procede de preparation d'un echantillon de microbiote fecal
PCT/FR2016/050958 WO2016170285A1 (fr) 2015-04-24 2016-04-22 Procédé de préparation d'un échantillon de microbiote fécal

Publications (1)

Publication Number Publication Date
DK3285784T3 true DK3285784T3 (da) 2020-08-24

Family

ID=53794336

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16723433.5T DK3285784T3 (da) 2015-04-24 2016-04-22 Fremgangsmåde til fremstilling af en prøve af fækal mikrobiota

Country Status (14)

Country Link
US (2) US10980839B2 (da)
EP (1) EP3285784B1 (da)
JP (1) JP6858747B2 (da)
CN (1) CN107530280B (da)
AU (1) AU2016252209B2 (da)
CA (1) CA2983192A1 (da)
DK (1) DK3285784T3 (da)
ES (1) ES2812854T3 (da)
FR (1) FR3035328B1 (da)
HU (1) HUE050430T2 (da)
IL (1) IL255100B (da)
PL (1) PL3285784T3 (da)
PT (1) PT3285784T (da)
WO (1) WO2016170285A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3045384B1 (fr) * 2015-12-18 2020-02-07 Institut National De La Recherche Agronomique Composition lyophilisee pour la conservation de microbiote dans son ecosysteme
US20180030403A1 (en) * 2016-07-28 2018-02-01 Bobban Subhadra Devices, systems and methods for the production of humanized gut commensal microbiota
FR3062063B1 (fr) * 2017-01-26 2019-04-19 Centre National De La Recherche Scientifique Microbiote fecal pour traiter des patients subissant une greffe de cellules souches hematopoietiques
JP2020521760A (ja) * 2017-05-26 2020-07-27 クレストヴォ・ホールディングス・エルエルシー 糞便微生物ベースの治療剤を含む凍結乾燥組成物ならびにそれを製造および使用する方法
EP3485879A1 (en) 2017-11-17 2019-05-22 Maat Pharma Pharmaceutical oral formulation comrpsing bacteria
FR3078627B1 (fr) * 2018-03-09 2020-11-13 Maat Pharma Procedure de collecte de selles et procede de preparation d'un echantillon pour transplantation de microbiote fecal
EP3597202A1 (en) * 2018-07-20 2020-01-22 Maat Pharma Fecal microbiota composition, for use in reducing treatment-induced inflammation
CN109010380A (zh) * 2018-08-21 2018-12-18 卓源健康科技有限公司 一种粪菌移植临床治疗中的肠道菌群制剂的工艺
EP3979916A4 (en) * 2019-06-07 2023-06-07 Anaerobe Systems MICROBIAL COLLECTIVE FORMULATIONS, DEVICES AND SYSTEMS
EP3895716A1 (en) 2020-04-17 2021-10-20 Maat Pharma Fmt performance prediction test to guide and optimize therapeutic management of gvhd patients
CN220564596U (zh) * 2020-07-15 2024-03-08 贝加尔生物医药研究中心有限公司 在厌氧条件下制备用于移植的粪便微生物供体的装置
RU2745125C1 (ru) * 2020-07-15 2021-03-22 Общество с ограниченной ответственностью «Байкальский центр биомедицинских исследований» (ООО «БайкалБиоМед») Устройство и способ подготовки в анаэробных условиях донорской фекальной микробиоты к трансплантации
CN112226369A (zh) * 2020-10-23 2021-01-15 重庆浦洛通基因医学研究院有限公司 一种肠道菌群保存液及制备方法
US20240115623A1 (en) 2020-12-23 2024-04-11 Maat Pharma Method of expanding a complex community of microorganisms
RU2761047C1 (ru) * 2021-03-10 2021-12-02 Федеральное государственное бюджетное научное учреждение "Иркутский научный центр хирургии и травматологии" Устройство для подготовки донорского фекального материала к трансплантации
EP4086337A1 (en) 2021-05-06 2022-11-09 Maat Pharma Method of predicting and then producing a mix of microbiota samples
EP4369344A1 (en) 2022-11-08 2024-05-15 Maat Pharma Determination of microbiota samples to produce a target mix product and prediction of mixes

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AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
JP5047358B2 (ja) * 2008-06-24 2012-10-10 森永乳業株式会社 検体中に含まれる微生物の生菌数測定に用いられる懸濁用希釈液および生菌数測定方法
KR20100088894A (ko) * 2009-02-02 2010-08-11 에이엠바이오 (주) 멤브레인 생물반응기를 이용한 고농도 유산균의 생산방법 및 유산균 동결건조 분말의 제조방법
DK2424972T3 (da) * 2009-04-30 2013-10-14 Actogenix Nv Kryobeskyttende midler til frysetørring af mælkesyrebakterier
CN102459568A (zh) * 2009-05-26 2012-05-16 先进生物营养公司 包含生物活性微生物和/或生物活性材料的稳定干粉组合物及其制造方法
US7888062B1 (en) * 2010-02-01 2011-02-15 Microbios, Inc. Process and composition for the manufacture of a microbial-based product
WO2011122949A1 (en) 2010-04-02 2011-10-06 Antonius Henricus Petrus Bosch Auxiliary device for receiving fecal matter
NZ618935A (en) 2010-08-04 2014-03-28 Karma Medical Prod Co Ltd Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
WO2014152484A1 (en) * 2013-03-14 2014-09-25 Regents Of The University Of Minnesota Freeze dried fecal microbiota for use in fecal microbial transplantation
WO2012122478A1 (en) * 2011-03-09 2012-09-13 Regents Of The University Of Minnesota Compositions and methods for transplantation of colon microbiota
CN103160489B (zh) * 2011-12-12 2015-01-14 润盈生物工程（上海）有限公司 日化微胶囊益生菌的制备方法
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AU2014275025B2 (en) * 2013-06-05 2016-12-01 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US20150037285A1 (en) * 2013-07-03 2015-02-05 New York University Methods for efficient transfer of viable and bioactive microbiota
KR102342925B1 (ko) 2015-06-09 2021-12-23 리바이오틱스, 인코퍼레이티드 미생물상 복원 치료(ｍｒｔ) 조성물 및 제조 방법
JP2018535254A (ja) 2015-10-26 2018-11-29 クレストヴォ・ホールディングス・エルエルシー 便微生物叢関連療法のための組成物及び方法

Also Published As

Publication number Publication date
EP3285784B1 (fr) 2020-07-08
US10980839B2 (en) 2021-04-20
JP2018514228A (ja) 2018-06-07
US20210154239A1 (en) 2021-05-27
HUE050430T2 (hu) 2020-12-28
JP6858747B2 (ja) 2021-04-14
US20180099012A1 (en) 2018-04-12
ES2812854T3 (es) 2021-03-18
FR3035328A1 (fr) 2016-10-28
EP3285784A1 (fr) 2018-02-28
IL255100B (en) 2022-09-01
AU2016252209A1 (en) 2017-12-07
WO2016170285A1 (fr) 2016-10-27
IL255100A0 (en) 2017-12-31
PL3285784T3 (pl) 2020-11-16
CN107530280B (zh) 2021-10-26
PT3285784T (pt) 2020-08-31
CN107530280A (zh) 2018-01-02
AU2016252209B2 (en) 2022-03-03
CA2983192A1 (fr) 2016-10-27
FR3035328B1 (fr) 2019-08-23

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