PL3212660T3 - Komórki ssacze wykazujące ekspresję antygenów cytomegalowirusowych - Google Patents

Komórki ssacze wykazujące ekspresję antygenów cytomegalowirusowych

Info

Publication number
PL3212660T3
PL3212660T3 PL15791768T PL15791768T PL3212660T3 PL 3212660 T3 PL3212660 T3 PL 3212660T3 PL 15791768 T PL15791768 T PL 15791768T PL 15791768 T PL15791768 T PL 15791768T PL 3212660 T3 PL3212660 T3 PL 3212660T3
Authority
PL
Poland
Prior art keywords
cells expressing
mammalian cells
cytomegalovirus antigens
expressing cytomegalovirus
antigens
Prior art date
Application number
PL15791768T
Other languages
English (en)
Inventor
Andrea Carfi
Claudio CIFERRI
Irmgard HOFMANN
Holger Laux
Anders Lilja
Yingxia Wen
Original Assignee
Glaxosmithkline Biologicals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals S.A. filed Critical Glaxosmithkline Biologicals S.A.
Publication of PL3212660T3 publication Critical patent/PL3212660T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0681Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16111Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16111Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16111Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16151Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL15791768T 2014-10-31 2015-10-29 Komórki ssacze wykazujące ekspresję antygenów cytomegalowirusowych PL3212660T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14191385.5A EP3015475A1 (en) 2014-10-31 2014-10-31 Mammalian cells expressing cytomegalovirus antigens
EP15791768.3A EP3212660B1 (en) 2014-10-31 2015-10-29 Mammalian cells expressing cytomegalovirus antigens
PCT/IB2015/058349 WO2016067239A1 (en) 2014-10-31 2015-10-29 Mammalian cells expressing cytomegalovirus antigens

Publications (1)

Publication Number Publication Date
PL3212660T3 true PL3212660T3 (pl) 2020-10-05

Family

ID=51844603

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15791768T PL3212660T3 (pl) 2014-10-31 2015-10-29 Komórki ssacze wykazujące ekspresję antygenów cytomegalowirusowych

Country Status (19)

Country Link
US (1) US10414802B2 (pl)
EP (2) EP3015475A1 (pl)
JP (1) JP6688297B2 (pl)
CN (1) CN107075486B (pl)
AR (1) AR102464A1 (pl)
BE (3) BE1023364B1 (pl)
BR (1) BR112017008827A2 (pl)
CA (1) CA2964859C (pl)
CY (1) CY1123405T1 (pl)
DK (1) DK3212660T3 (pl)
ES (1) ES2799735T3 (pl)
HR (1) HRP20200932T1 (pl)
HU (1) HUE049356T2 (pl)
LT (1) LT3212660T (pl)
MX (1) MX2017005661A (pl)
PL (1) PL3212660T3 (pl)
PT (1) PT3212660T (pl)
SI (1) SI3212660T1 (pl)
WO (1) WO2016067239A1 (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2513768B (en) 2012-07-06 2015-04-15 Novartis Ag Complexes of cytomegalovirus proteins and nucleic acids encoding such proteins
WO2015048744A2 (en) 2013-09-30 2015-04-02 Moderna Therapeutics, Inc. Polynucleotides encoding immune modulating polypeptides
AU2015254913B2 (en) * 2014-04-29 2018-05-17 Novartis Ag Novel vertebrate cells and methods for recombinantly expressing a polypeptide of interest
EP3048114A1 (en) 2015-01-22 2016-07-27 Novartis AG Cytomegalovirus antigens and uses thereof
WO2017070613A1 (en) 2015-10-22 2017-04-27 Modernatx, Inc. Human cytomegalovirus vaccine
JP6980780B2 (ja) 2016-10-21 2021-12-15 モデルナティーエックス, インコーポレイテッド ヒトサイトメガロウイルスワクチン
CN107723276B (zh) * 2017-11-02 2021-08-13 上海交通大学 一种稳定高表达目标产物的细胞株的构建方法和试剂盒
EP3787676A2 (en) 2018-05-04 2021-03-10 Spybiotech Limited Vaccine composition
CA3121915A1 (en) * 2018-12-10 2020-06-18 Km Biologics Co., Ltd. Vaccine for preventing or treating congenital infection with cytomegalovirus
US11406703B2 (en) 2020-08-25 2022-08-09 Modernatx, Inc. Human cytomegalovirus vaccine
CA3199996A1 (en) * 2020-12-02 2022-06-09 Pirada ALLEN Multicistronic rna vaccines and uses thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
DK0747485T3 (da) 1989-11-06 1999-08-16 Cell Genesys Inc Fremstilling af proteiner ved anvendelse af homolog rekombination
US5589392A (en) 1991-01-14 1996-12-31 Stratagene Nucleic acid construct encoding a nuclear transport peptide operatively linked to an inducible promoter
US7704510B2 (en) 2006-06-07 2010-04-27 The Trustees Of Princeton University Cytomegalovirus surface protein complex for use in vaccines and as a drug target
US20140030292A1 (en) * 2010-10-11 2014-01-30 Novartis Ag Antigen delivery platforms
GB2513768B (en) 2012-07-06 2015-04-15 Novartis Ag Complexes of cytomegalovirus proteins and nucleic acids encoding such proteins
CN104884467A (zh) 2012-12-18 2015-09-02 诺华股份有限公司 在遗传修饰的哺乳动物细胞中生产治疗性蛋白质
US11203631B2 (en) 2013-12-20 2021-12-21 Novartis Ag Eukaryotic cells and methods for recombinantly expressing a product of interest
EP3083677B1 (en) 2013-12-20 2019-08-28 Novartis AG Novel eukaryotic cells and methods for recombinantly expressing a product of interest
WO2015165480A1 (en) 2014-04-30 2015-11-05 Institute For Research In Biomedicine Human cytomegalovirus vaccine compositions and method of producing the same
AU2015254913B2 (en) 2014-04-29 2018-05-17 Novartis Ag Novel vertebrate cells and methods for recombinantly expressing a polypeptide of interest

Also Published As

Publication number Publication date
EP3212660A1 (en) 2017-09-06
BR112017008827A2 (pt) 2018-03-27
LT3212660T (lt) 2020-07-10
BE1023841A1 (fr) 2017-08-09
PT3212660T (pt) 2020-06-23
CY1123405T1 (el) 2021-12-31
BE1023840A1 (fr) 2017-08-09
SI3212660T1 (sl) 2020-07-31
CA2964859C (en) 2023-04-04
CA2964859A1 (en) 2016-05-06
DK3212660T3 (da) 2020-06-15
AR102464A1 (es) 2017-03-01
BE1023364B1 (fr) 2017-02-20
ES2799735T3 (es) 2020-12-21
US20170362278A1 (en) 2017-12-21
HUE049356T2 (hu) 2020-09-28
HRP20200932T1 (hr) 2020-09-18
JP2017534283A (ja) 2017-11-24
WO2016067239A1 (en) 2016-05-06
BE1023841B1 (fr) 2017-08-10
EP3015475A1 (en) 2016-05-04
BE1023364A1 (fr) 2017-02-20
EP3212660B1 (en) 2020-03-25
BE1023840B1 (fr) 2017-08-10
CN107075486B (zh) 2021-06-22
JP6688297B2 (ja) 2020-04-28
CN107075486A (zh) 2017-08-18
US10414802B2 (en) 2019-09-17
MX2017005661A (es) 2017-06-26

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