PL3194612T3 - Metody ilościowej analizy genetycznej dna wolnego od komórek - Google Patents

Metody ilościowej analizy genetycznej dna wolnego od komórek

Info

Publication number
PL3194612T3
PL3194612T3 PL14761762.5T PL14761762T PL3194612T3 PL 3194612 T3 PL3194612 T3 PL 3194612T3 PL 14761762 T PL14761762 T PL 14761762T PL 3194612 T3 PL3194612 T3 PL 3194612T3
Authority
PL
Poland
Prior art keywords
cell
methods
free dna
genetic analysis
quantitative genetic
Prior art date
Application number
PL14761762.5T
Other languages
English (en)
Polish (pl)
Inventor
Christopher K. Raymond
Lee P. Lim
Christopher D. Armour
Original Assignee
Resolution Bioscience, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Resolution Bioscience, Inc. filed Critical Resolution Bioscience, Inc.
Publication of PL3194612T3 publication Critical patent/PL3194612T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1093General methods of preparing gene libraries, not provided for in other subgroups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL14761762.5T 2014-08-22 2014-08-22 Metody ilościowej analizy genetycznej dna wolnego od komórek PL3194612T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2014/052317 WO2016028316A1 (en) 2014-08-22 2014-08-22 Methods for quantitative genetic analysis of cell free dna

Publications (1)

Publication Number Publication Date
PL3194612T3 true PL3194612T3 (pl) 2024-11-04

Family

ID=51494529

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14761762.5T PL3194612T3 (pl) 2014-08-22 2014-08-22 Metody ilościowej analizy genetycznej dna wolnego od komórek

Country Status (11)

Country Link
EP (2) EP4410978A3 (enExample)
JP (1) JP6709778B2 (enExample)
CN (2) CN107002118B (enExample)
CA (1) CA2957657A1 (enExample)
DK (1) DK3194612T3 (enExample)
ES (1) ES2984266T3 (enExample)
HU (1) HUE068191T2 (enExample)
PL (1) PL3194612T3 (enExample)
PT (1) PT3194612T (enExample)
SG (1) SG11201701113WA (enExample)
WO (1) WO2016028316A1 (enExample)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11111543B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
US12152275B2 (en) 2010-05-18 2024-11-26 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
US12221653B2 (en) 2010-05-18 2025-02-11 Natera, Inc. Methods for simultaneous amplification of target loci
US10179937B2 (en) 2014-04-21 2019-01-15 Natera, Inc. Detecting mutations and ploidy in chromosomal segments
CA2824387C (en) 2011-02-09 2019-09-24 Natera, Inc. Methods for non-invasive prenatal ploidy calling
WO2013059740A1 (en) 2011-10-21 2013-04-25 Foundation Medicine, Inc. Novel alk and ntrk1 fusion molecules and uses thereof
US9892230B2 (en) 2012-03-08 2018-02-13 The Chinese University Of Hong Kong Size-based analysis of fetal or tumor DNA fraction in plasma
US20140100126A1 (en) 2012-08-17 2014-04-10 Natera, Inc. Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
HK1214831A1 (zh) 2012-11-05 2016-08-05 Foundation Medicine, Inc. 新型融合分子及其应用
CN111254500B (zh) 2012-12-10 2024-01-23 分析生物科学有限公司 靶向基因组分析的方法
US12492429B2 (en) 2014-04-21 2025-12-09 Natera, Inc. Detecting mutations and ploidy in chromosomal segments
US20180173845A1 (en) 2014-06-05 2018-06-21 Natera, Inc. Systems and Methods for Detection of Aneuploidy
PT3543356T (pt) 2014-07-18 2021-10-04 Univ Hong Kong Chinese Análise dos padrões de metilação de tecidos em mistura de adn
US20160053301A1 (en) 2014-08-22 2016-02-25 Clearfork Bioscience, Inc. Methods for quantitative genetic analysis of cell free dna
JP7441584B6 (ja) * 2014-08-22 2024-03-15 レゾリューション バイオサイエンス, インコーポレイテッド 無細胞DNA(cfDNA)の定量的遺伝子解析のための方法
US10364467B2 (en) 2015-01-13 2019-07-30 The Chinese University Of Hong Kong Using size and number aberrations in plasma DNA for detecting cancer
DK3294906T3 (en) 2015-05-11 2024-08-05 Natera Inc Methods for determining ploidy
ES2856598T3 (es) 2015-11-11 2021-09-27 Resolution Bioscience Inc Construcción de alta eficiencia de bibliotecas de ADN
US11479878B2 (en) 2016-03-16 2022-10-25 Dana-Farber Cancer Institute, Inc. Methods for genome characterization
ES2913468T3 (es) 2016-04-15 2022-06-02 Natera Inc Métodos para la detección del cáncer de pulmón.
WO2017190067A1 (en) 2016-04-28 2017-11-02 Impact Genomics, Inc. Methods of assessing and monitoring tumor load
US20200181681A1 (en) * 2016-04-29 2020-06-11 The Medical College Of Wisconsin, Inc. Multiplexed optimized mismatch amplification (moma)-real time pcr for assessing cancer
CN106047998B (zh) * 2016-05-27 2019-11-12 深圳市海普洛斯生物科技有限公司 一种肺癌基因的检测方法及应用
WO2018013579A1 (en) * 2016-07-11 2018-01-18 cARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY Sweat as a biofluid for analysis and disease identification
SG11201901371XA (en) * 2016-08-25 2019-03-28 Resolution Bioscience Inc Methods for the detection of genomic copy changes in dna samples
GB201618485D0 (en) 2016-11-02 2016-12-14 Ucl Business Plc Method of detecting tumour recurrence
AU2017363180B2 (en) * 2016-11-17 2023-11-02 LGC Clinical Diagnostics, Inc. Methods for preparing DNA reference material and controls
CA3039685A1 (en) 2016-11-30 2018-06-07 The Chinese University Of Hong Kong Analysis of cell-free dna in urine and other samples
JP2020524519A (ja) 2017-06-20 2020-08-20 ザ メディカル カレッジ オブ ウィスコンシン,インコーポレイテッドThe Medical College of Wisconsin, Inc. 全セルフリーdnaによる移植合併症リスクの評価
US12084720B2 (en) 2017-12-14 2024-09-10 Natera, Inc. Assessing graft suitability for transplantation
CN111684078B (zh) * 2018-02-12 2024-04-19 豪夫迈·罗氏有限公司 通过评价肿瘤遗传异质性来预测对治疗的应答的方法
WO2019173552A1 (en) 2018-03-08 2019-09-12 St. John's University Circulating serum cell-free dna biomarkers and methods
JP7573443B2 (ja) 2018-04-14 2024-10-25 ナテラ, インコーポレイテッド 循環腫瘍dnaの個別化された検出を用いる癌検出およびモニタリングの方法
CN108517567B (zh) * 2018-04-20 2020-08-11 江苏康为世纪生物科技有限公司 用于cfDNA建库的接头、引物组、试剂盒和建库方法
US12234509B2 (en) 2018-07-03 2025-02-25 Natera, Inc. Methods for detection of donor-derived cell-free DNA
CN108676891B (zh) * 2018-07-12 2022-02-01 吉林大学 一种直肠腺癌易感性预测试剂盒及系统
US11926821B2 (en) * 2018-10-22 2024-03-12 The Chinese University Of Hong Kong Cell-free DNA quality
US20220064708A1 (en) * 2019-01-15 2022-03-03 General Incorporated Association, Bio Education Laboratory Method for preparing liquid biopsy using pva sponge
US11931674B2 (en) 2019-04-04 2024-03-19 Natera, Inc. Materials and methods for processing blood samples
CN112301103B (zh) * 2019-08-02 2023-04-11 北京贝瑞和康生物技术有限公司 一种非特异性扩增天然短片段核酸的方法和试剂盒
CN110819622A (zh) * 2019-10-09 2020-02-21 广州达正生物科技有限公司 一种快速提取石蜡组织rna的方法
CN111254194B (zh) * 2020-01-13 2021-09-07 东南大学 基于cfDNA的测序及数据分析的癌症相关生物标记及其在cfDNA样品分类中的应用
US11211147B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing
US11211144B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Methods and systems for refining copy number variation in a liquid biopsy assay
US11475981B2 (en) 2020-02-18 2022-10-18 Tempus Labs, Inc. Methods and systems for dynamic variant thresholding in a liquid biopsy assay
WO2022020662A2 (en) * 2020-07-24 2022-01-27 Cornell University Methods for assessing the severity and progression of sars-cov2 infections using cell-free dna
US20220073906A1 (en) * 2020-09-08 2022-03-10 Resolution Bioscience, Inc. Adaptors and methods for high efficiency construction of genetic libraries and genetic analysis
US20250129429A1 (en) * 2021-09-10 2025-04-24 Foundation Medicine, Inc. Gene fusions in sarcoma

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9023769B2 (en) * 2009-11-30 2015-05-05 Complete Genomics, Inc. cDNA library for nucleic acid sequencing
EP2426217A1 (en) * 2010-09-03 2012-03-07 Centre National de la Recherche Scientifique (CNRS) Analytical methods for cell free nucleic acids and applications
US20130288915A1 (en) * 2012-04-27 2013-10-31 Htg Molecular Diagnostics, Inc. Compositions and methods for alk molecular testing
WO2014052487A1 (en) * 2012-09-28 2014-04-03 Cepheid Two-primer pcr for microrna multiplex assay
US20150291953A1 (en) * 2012-11-02 2015-10-15 Enzymatics Inc. Methods and kits for nucleic acid sample preparation for sequencing
CN111254500B (zh) * 2012-12-10 2024-01-23 分析生物科学有限公司 靶向基因组分析的方法
EP2954054B1 (en) * 2013-02-08 2018-12-05 Qiagen GmbH Method for separating dna by size

Also Published As

Publication number Publication date
CN115029342B (zh) 2025-04-08
DK3194612T3 (da) 2024-10-14
PT3194612T (pt) 2024-10-02
CN107002118B (zh) 2022-07-08
JP6709778B2 (ja) 2020-06-17
CA2957657A1 (en) 2016-02-25
SG11201701113WA (en) 2017-03-30
HUE068191T2 (hu) 2024-12-28
WO2016028316A1 (en) 2016-02-25
EP4410978A2 (en) 2024-08-07
EP4410978A3 (en) 2024-10-30
CN107002118A (zh) 2017-08-01
EP3194612A1 (en) 2017-07-26
JP2017525371A (ja) 2017-09-07
CN115029342A (zh) 2022-09-09
EP3194612B1 (en) 2024-07-03
ES2984266T3 (es) 2024-10-29

Similar Documents

Publication Publication Date Title
PL3194612T3 (pl) Metody ilościowej analizy genetycznej dna wolnego od komórek
IL249619A0 (en) Analysis of nucleic acid sequences
BR112017008877A2 (pt) métodos e composições para sequenciamento de ácido nucleico-alvo
DK4023755T5 (da) Kunstige nukleinsyremolekyler til forbedret proteinudtrykkelse
DK3158054T3 (da) Genetisk modificerede bakterier og fremgangsmåder til genetisk modifikation af bakterier
EP4112738C0 (en) MULTIGENE ANALYSIS OF TUMOR SAMPLES
HUE052552T2 (hu) Javított nukleinsav-konstrukciók eukarióta génexpresszióhoz
LT3201361T (lt) Laisvai cirkuliuojančios dnr kiekybinio įvertinimo būdai
EP3472757C0 (en) COMPUTERIZED MICROEXPRESSION ANALYSIS
DK3108009T3 (da) Fremgangsmåder og sammensætninger til DNA-profilering
PL3118311T3 (pl) Antysensowny kwas nukleinowy
PT3215532T (pt) Anticorpos anti-tim3 e métodos de utilização
EP3461890C0 (en) TOTAL FERMENTATION OF OLIGOSACCHARIDES
BR112017009540A2 (pt) biorreator usando macroalgas
SG11201607796TA (en) Nanopore-based analysis of protein characteristics
SG11201703178YA (en) Method for ketonisation of biological material
DK3699289T3 (da) Prøveklargøring til nukleinsyreamplifikation
LT3662910T (lt) Trail geno indukcijai skirtas farmakoforas
DK3094731T3 (da) Saccharidmodificerede nukleinsyremolekyler
IL249395A0 (en) Quantitative analysis of transgenic proteins
GB201410646D0 (en) Methods of increasing sequencing accuracy
EP2998732C0 (en) ANALYSIS PROCESS
SG11201610431WA (en) Methods and reagents for purification of proteins
IL257728B (en) Systems and methods for genetic analysis of metastases
PT3207164T (pt) Métodos de cultura semi-contínuos