SG11201701113WA - Methods for quantitative genetic analysis of cell free dna - Google Patents
Methods for quantitative genetic analysis of cell free dnaInfo
- Publication number
- SG11201701113WA SG11201701113WA SG11201701113WA SG11201701113WA SG11201701113WA SG 11201701113W A SG11201701113W A SG 11201701113WA SG 11201701113W A SG11201701113W A SG 11201701113WA SG 11201701113W A SG11201701113W A SG 11201701113WA SG 11201701113W A SG11201701113W A SG 11201701113WA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- cell free
- free dna
- genetic analysis
- quantitative genetic
- Prior art date
Links
- 238000012252 genetic analysis Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2014/052317 WO2016028316A1 (en) | 2014-08-22 | 2014-08-22 | Methods for quantitative genetic analysis of cell free dna |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201701113WA true SG11201701113WA (en) | 2017-03-30 |
Family
ID=51494529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201701113WA SG11201701113WA (en) | 2014-08-22 | 2014-08-22 | Methods for quantitative genetic analysis of cell free dna |
Country Status (11)
| Country | Link |
|---|---|
| EP (2) | EP4410978A3 (enExample) |
| JP (1) | JP6709778B2 (enExample) |
| CN (2) | CN107002118B (enExample) |
| CA (1) | CA2957657A1 (enExample) |
| DK (1) | DK3194612T3 (enExample) |
| ES (1) | ES2984266T3 (enExample) |
| HU (1) | HUE068191T2 (enExample) |
| PL (1) | PL3194612T3 (enExample) |
| PT (1) | PT3194612T (enExample) |
| SG (1) | SG11201701113WA (enExample) |
| WO (1) | WO2016028316A1 (enExample) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| BR112013020220B1 (pt) | 2011-02-09 | 2020-03-17 | Natera, Inc. | Método para determinar o estado de ploidia de um cromossomo em um feto em gestação |
| US9892230B2 (en) | 2012-03-08 | 2018-02-13 | The Chinese University Of Hong Kong | Size-based analysis of fetal or tumor DNA fraction in plasma |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| EP4223770A3 (en) | 2012-11-05 | 2023-10-18 | Foundation Medicine, Inc. | Novel fusion molecules and uses thereof |
| EP3561072A1 (en) | 2012-12-10 | 2019-10-30 | Resolution Bioscience, Inc. | Methods for targeted genomic analysis |
| EP3134541B1 (en) | 2014-04-21 | 2020-08-19 | Natera, Inc. | Detecting copy number variations (cnv) of chromosomal segments in cancer |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| US20180173846A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| US11062789B2 (en) | 2014-07-18 | 2021-07-13 | The Chinese University Of Hong Kong | Methylation pattern analysis of tissues in a DNA mixture |
| JP7441584B6 (ja) * | 2014-08-22 | 2024-03-15 | レゾリューション バイオサイエンス， インコーポレイテッド | 無細胞ＤＮＡ（ｃｆＤＮＡ）の定量的遺伝子解析のための方法 |
| US20160053301A1 (en) | 2014-08-22 | 2016-02-25 | Clearfork Bioscience, Inc. | Methods for quantitative genetic analysis of cell free dna |
| US10364467B2 (en) | 2015-01-13 | 2019-07-30 | The Chinese University Of Hong Kong | Using size and number aberrations in plasma DNA for detecting cancer |
| US11479812B2 (en) | 2015-05-11 | 2022-10-25 | Natera, Inc. | Methods and compositions for determining ploidy |
| EP3889257A1 (en) * | 2015-11-11 | 2021-10-06 | Resolution Bioscience, Inc. | High efficiency construction of dna libraries |
| US11479878B2 (en) | 2016-03-16 | 2022-10-25 | Dana-Farber Cancer Institute, Inc. | Methods for genome characterization |
| RU2760913C2 (ru) | 2016-04-15 | 2021-12-01 | Натера, Инк. | Способы выявления рака легкого |
| WO2017190067A1 (en) | 2016-04-28 | 2017-11-02 | Impact Genomics, Inc. | Methods of assessing and monitoring tumor load |
| AU2017258799A1 (en) * | 2016-04-29 | 2018-12-20 | The Medical College Of Wisconsin, Inc. | Multiplexed optimized mismatch amplification (moma)-real time pcr for assessing cancer |
| CN106047998B (zh) * | 2016-05-27 | 2019-11-12 | 深圳市海普洛斯生物科技有限公司 | 一种肺癌基因的检测方法及应用 |
| WO2018013579A1 (en) * | 2016-07-11 | 2018-01-18 | cARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | Sweat as a biofluid for analysis and disease identification |
| AU2017315769B2 (en) * | 2016-08-25 | 2024-02-01 | Resolution Bioscience, Inc. | Methods for the detection of genomic copy changes in DNA samples |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| ES2980292T3 (es) * | 2016-11-17 | 2024-09-30 | Lgc Clinical Diagnostics Inc | Métodos para preparar material de referencia y controles de ADN |
| WO2018099418A1 (en) | 2016-11-30 | 2018-06-07 | The Chinese University Of Hong Kong | Analysis of cell-free dna in urine and other samples |
| CA3067637A1 (en) | 2017-06-20 | 2018-12-27 | The Medical College Of Wisconsin, Inc. | Assessing transplant complication risk with total cell-free dna |
| US12084720B2 (en) | 2017-12-14 | 2024-09-10 | Natera, Inc. | Assessing graft suitability for transplantation |
| EP3752643B1 (en) * | 2018-02-12 | 2024-01-17 | F. Hoffmann-La Roche AG | Method of predicting response to therapy by assessing tumor genetic heterogeneity |
| JP2021514663A (ja) * | 2018-03-08 | 2021-06-17 | セント・ジョーンズ・ユニバーシティＳｔ． Ｊｏｈｎｓ Ｕｎｉｖｅｒｓｉｔｙ | 循環性血清無細胞ｄｎａバイオマーカー及び方法 |
| US12024738B2 (en) | 2018-04-14 | 2024-07-02 | Natera, Inc. | Methods for cancer detection and monitoring |
| CN108517567B (zh) * | 2018-04-20 | 2020-08-11 | 江苏康为世纪生物科技有限公司 | 用于cfDNA建库的接头、引物组、试剂盒和建库方法 |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| CN108676891B (zh) * | 2018-07-12 | 2022-02-01 | 吉林大学 | 一种直肠腺癌易感性预测试剂盒及系统 |
| US11926821B2 (en) * | 2018-10-22 | 2024-03-12 | The Chinese University Of Hong Kong | Cell-free DNA quality |
| JP7560112B2 (ja) * | 2019-01-15 | 2024-10-02 | 一般社団法人生命科学教育研究所 | Ｐｖａスポンジを用いるリキッドバイオプシーの調製方法 |
| US11931674B2 (en) | 2019-04-04 | 2024-03-19 | Natera, Inc. | Materials and methods for processing blood samples |
| CN112301103B (zh) * | 2019-08-02 | 2023-04-11 | 北京贝瑞和康生物技术有限公司 | 一种非特异性扩增天然短片段核酸的方法和试剂盒 |
| CN110819622A (zh) * | 2019-10-09 | 2020-02-21 | 广州达正生物科技有限公司 | 一种快速提取石蜡组织rna的方法 |
| CN111254194B (zh) * | 2020-01-13 | 2021-09-07 | 东南大学 | 基于cfDNA的测序及数据分析的癌症相关生物标记及其在cfDNA样品分类中的应用 |
| US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
| US11211147B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing |
| US11211144B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Methods and systems for refining copy number variation in a liquid biopsy assay |
| US20230323455A1 (en) * | 2020-07-24 | 2023-10-12 | Cornell University | Methods for assessing the severity and progression of sars-cov2 infections using cell-free dna |
| KR20230065295A (ko) * | 2020-09-08 | 2023-05-11 | 레졸루션 바이오사이언스, 인크. | 유전자 라이브러리 및 유전자 분석의 고효율성 구축을 위한 어댑터 및 방법 |
| US20250129429A1 (en) * | 2021-09-10 | 2025-04-24 | Foundation Medicine, Inc. | Gene fusions in sarcoma |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9023769B2 (en) * | 2009-11-30 | 2015-05-05 | Complete Genomics, Inc. | cDNA library for nucleic acid sequencing |
| EP2426217A1 (en) * | 2010-09-03 | 2012-03-07 | Centre National de la Recherche Scientifique (CNRS) | Analytical methods for cell free nucleic acids and applications |
| US20130288915A1 (en) * | 2012-04-27 | 2013-10-31 | Htg Molecular Diagnostics, Inc. | Compositions and methods for alk molecular testing |
| CA2886605A1 (en) * | 2012-09-28 | 2014-04-03 | Cepheid | Two-primer pcr for microrna multiplex assay |
| US20150291953A1 (en) * | 2012-11-02 | 2015-10-15 | Enzymatics Inc. | Methods and kits for nucleic acid sample preparation for sequencing |
| EP3561072A1 (en) * | 2012-12-10 | 2019-10-30 | Resolution Bioscience, Inc. | Methods for targeted genomic analysis |
| EP2954054B1 (en) * | 2013-02-08 | 2018-12-05 | Qiagen GmbH | Method for separating dna by size |
-
2014
- 2014-08-22 DK DK14761762.5T patent/DK3194612T3/da active
- 2014-08-22 CA CA2957657A patent/CA2957657A1/en active Pending
- 2014-08-22 PT PT147617625T patent/PT3194612T/pt unknown
- 2014-08-22 ES ES14761762T patent/ES2984266T3/es active Active
- 2014-08-22 EP EP24182096.8A patent/EP4410978A3/en active Pending
- 2014-08-22 SG SG11201701113WA patent/SG11201701113WA/en unknown
- 2014-08-22 WO PCT/US2014/052317 patent/WO2016028316A1/en not_active Ceased
- 2014-08-22 CN CN201480081729.4A patent/CN107002118B/zh active Active
- 2014-08-22 EP EP14761762.5A patent/EP3194612B1/en active Active
- 2014-08-22 PL PL14761762.5T patent/PL3194612T3/pl unknown
- 2014-08-22 CN CN202210630244.2A patent/CN115029342B/zh active Active
- 2014-08-22 JP JP2017510397A patent/JP6709778B2/ja active Active
- 2014-08-22 HU HUE14761762A patent/HUE068191T2/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4410978A2 (en) | 2024-08-07 |
| EP4410978A3 (en) | 2024-10-30 |
| CN115029342B (zh) | 2025-04-08 |
| CN115029342A (zh) | 2022-09-09 |
| DK3194612T3 (da) | 2024-10-14 |
| CA2957657A1 (en) | 2016-02-25 |
| ES2984266T3 (es) | 2024-10-29 |
| HUE068191T2 (hu) | 2024-12-28 |
| EP3194612B1 (en) | 2024-07-03 |
| CN107002118A (zh) | 2017-08-01 |
| JP6709778B2 (ja) | 2020-06-17 |
| PL3194612T3 (pl) | 2024-11-04 |
| JP2017525371A (ja) | 2017-09-07 |
| CN107002118B (zh) | 2022-07-08 |
| EP3194612A1 (en) | 2017-07-26 |
| PT3194612T (pt) | 2024-10-02 |
| WO2016028316A1 (en) | 2016-02-25 |
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