PL3162804T3 - Nowa pochodna benzodiazepiny i jej zastosowanie - Google Patents

Nowa pochodna benzodiazepiny i jej zastosowanie

Info

Publication number
PL3162804T3
PL3162804T3 PL15824012T PL15824012T PL3162804T3 PL 3162804 T3 PL3162804 T3 PL 3162804T3 PL 15824012 T PL15824012 T PL 15824012T PL 15824012 T PL15824012 T PL 15824012T PL 3162804 T3 PL3162804 T3 PL 3162804T3
Authority
PL
Poland
Prior art keywords
benzodiazepine derivative
new benzodiazepine
new
derivative
benzodiazepine
Prior art date
Application number
PL15824012T
Other languages
English (en)
Inventor
Qingeng LI
Tao Wang
Jianyong Xie
Guisheng Zhang
Xiangqing Xu
Original Assignee
Jiangsu Nhwaluokang Pharmaceutical Research And Development Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Nhwaluokang Pharmaceutical Research And Development Co., Ltd. filed Critical Jiangsu Nhwaluokang Pharmaceutical Research And Development Co., Ltd.
Publication of PL3162804T3 publication Critical patent/PL3162804T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL15824012T 2014-07-23 2015-07-22 Nowa pochodna benzodiazepiny i jej zastosowanie PL3162804T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201410352439 2014-07-23
EP15824012.7A EP3162804B1 (en) 2014-07-23 2015-07-22 New benzodiazepine derivative and use thereof
PCT/CN2015/084770 WO2016011943A1 (zh) 2014-07-23 2015-07-22 新的苯并二氮杂䓬类衍生物及其用途

Publications (1)

Publication Number Publication Date
PL3162804T3 true PL3162804T3 (pl) 2020-04-30

Family

ID=55162517

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15824012T PL3162804T3 (pl) 2014-07-23 2015-07-22 Nowa pochodna benzodiazepiny i jej zastosowanie

Country Status (9)

Country Link
US (1) US9994578B2 (pl)
EP (1) EP3162804B1 (pl)
CN (1) CN106804107B (pl)
DK (1) DK3162804T3 (pl)
ES (1) ES2751627T3 (pl)
HU (1) HUE047450T2 (pl)
PL (1) PL3162804T3 (pl)
PT (1) PT3162804T (pl)
WO (1) WO2016011943A1 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2916845T3 (es) * 2017-02-09 2022-07-06 Assia Chem Ind Ltd Proceso para la preparación de remimazolam y formas en estado sólido de sales de remimazolam
CN108047229A (zh) * 2017-12-15 2018-05-18 宜昌人福药业有限责任公司 苯并二氮杂*类化合物
CN108003164A (zh) * 2017-12-15 2018-05-08 宜昌人福药业有限责任公司 苯并二氮杂*类化合物
CN108033964B (zh) * 2017-12-28 2021-02-09 杭州奥默医药股份有限公司 一种吡啶基咪唑并苯并二氮杂卓丙酸酯化合物及其合成和应用
BR112020016323A2 (pt) * 2018-02-13 2020-12-15 Jiangsu Nhwaluokang Pharmaceutical Research And Development Co., Ltd. Cloridrato de derivado de benzodiazepina e forma de cristal, método de preparação e aplicação do mesmo
CN112321594B (zh) * 2020-12-07 2022-05-20 扬子江药业集团有限公司 一种苯并二氮杂䓬类药物的制备方法
CN116102557B (zh) * 2021-11-09 2024-04-26 四川大学华西医院 苯二氮卓类化合物及其制备方法和在医药上的用途
CN114588164B (zh) * 2022-04-19 2023-08-11 天津医科大学总医院 瑞马唑仑在预防围术期低体温和寒战中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9911152D0 (en) 1999-05-14 1999-07-14 Glaxo Group Ltd Short-acting benzodiazepines
KR20170091770A (ko) * 2006-07-10 2017-08-09 파이온 유케이 리미티드 속효형 벤조디아제핀 염 및 이의 중합체 형태
EP2450039A1 (en) * 2010-11-08 2012-05-09 PAION UK Ltd. Dosing regimen for sedation with CNS 7056 (Remimazolam)
CN102964349A (zh) * 2011-08-31 2013-03-13 江苏恒瑞医药股份有限公司 苯并二氮杂*衍生物的托西酸盐及其多晶型、它们的制备方法和用途
UA115063C2 (uk) * 2012-05-22 2017-09-11 ПАЙОН ЮКей ЛІМІТЕД Композиції, які містять бензодіазепіни короткої дії
CN104768557A (zh) * 2012-08-31 2015-07-08 Paion英国有限公司 催眠镇静剂的给药方案
CN103232454A (zh) * 2013-05-05 2013-08-07 王元青 治疗精神疾病的药物
CN103202815B (zh) * 2013-05-05 2014-09-24 李友香 治疗精神疾病的注射剂

Also Published As

Publication number Publication date
EP3162804A8 (en) 2017-08-09
EP3162804A1 (en) 2017-05-03
PT3162804T (pt) 2019-12-16
EP3162804B1 (en) 2019-10-09
US9994578B2 (en) 2018-06-12
CN106804107B (zh) 2019-03-12
CN106804107A (zh) 2017-06-06
WO2016011943A1 (zh) 2016-01-28
HUE047450T2 (hu) 2020-04-28
ES2751627T3 (es) 2020-04-01
EP3162804A4 (en) 2018-01-10
DK3162804T3 (da) 2020-01-13
US20170217965A1 (en) 2017-08-03

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