PL3157930T3 - Sposoby wytwarzania związków heterocyklicznych 1,3-benzodioksolu - Google Patents

Sposoby wytwarzania związków heterocyklicznych 1,3-benzodioksolu

Info

Publication number
PL3157930T3
PL3157930T3 PL15730183T PL15730183T PL3157930T3 PL 3157930 T3 PL3157930 T3 PL 3157930T3 PL 15730183 T PL15730183 T PL 15730183T PL 15730183 T PL15730183 T PL 15730183T PL 3157930 T3 PL3157930 T3 PL 3157930T3
Authority
PL
Poland
Prior art keywords
preparation
methods
heterocyclic compounds
benzodioxole
benzodioxole heterocyclic
Prior art date
Application number
PL15730183T
Other languages
English (en)
Polish (pl)
Inventor
Bjørn METZLER
André FALDT
Original Assignee
Leo Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharma As filed Critical Leo Pharma As
Publication of PL3157930T3 publication Critical patent/PL3157930T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL15730183T 2014-06-23 2015-06-22 Sposoby wytwarzania związków heterocyklicznych 1,3-benzodioksolu PL3157930T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14173397 2014-06-23
PCT/EP2015/063942 WO2015197534A2 (en) 2014-06-23 2015-06-22 Methods for the preparation of 1,3-benzodioxole heterocyclic compounds
EP15730183.9A EP3157930B1 (en) 2014-06-23 2015-06-22 Methods for the preparation of 1,3-benzodioxole heterocyclic compounds

Publications (1)

Publication Number Publication Date
PL3157930T3 true PL3157930T3 (pl) 2019-04-30

Family

ID=50980952

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15730183T PL3157930T3 (pl) 2014-06-23 2015-06-22 Sposoby wytwarzania związków heterocyklicznych 1,3-benzodioksolu

Country Status (18)

Country Link
US (1) US9908894B2 (show.php)
EP (1) EP3157930B1 (show.php)
JP (1) JP6785666B2 (show.php)
KR (1) KR20170016894A (show.php)
CN (1) CN106459081B (show.php)
AU (1) AU2015279428B2 (show.php)
BR (1) BR112016029510A2 (show.php)
CA (1) CA2953284A1 (show.php)
DK (1) DK3157930T3 (show.php)
ES (1) ES2702451T3 (show.php)
IL (1) IL249336A0 (show.php)
MX (1) MX2016016378A (show.php)
PL (1) PL3157930T3 (show.php)
PT (1) PT3157930T (show.php)
RU (1) RU2697251C2 (show.php)
TW (1) TW201613934A (show.php)
WO (1) WO2015197534A2 (show.php)
ZA (1) ZA201608442B (show.php)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3390407T (pt) 2015-12-18 2023-11-03 Union Therapeutics As Métodos para a preparação de compostos heterocíclicos de 1,3-benzodioxole
CN110741005B (zh) 2017-06-20 2024-04-12 联合疗法公司 用于制备1,3-苯并二氧杂环戊烯杂环化合物的方法
CN111727191B (zh) 2017-12-15 2024-01-05 联合疗法公司 取代的氮杂环丁烷二氢噻吩并吡啶类化合物及其作为磷酸二酯酶抑制剂的用途
USD914676S1 (en) 2018-05-11 2021-03-30 Samsung Electronics Co., Ltd. Notebook computer
ES2957495T3 (es) 2019-01-15 2024-01-19 Union Therapeutics As Formulaciones de comprimidos de liberación modificada que contienen inhibidores de fosfodiesterasa
BR112023019309A2 (pt) 2021-03-22 2023-10-31 Union Therapeutics As Tratamento de hidradenite supurativa com orismilaste
GB202205715D0 (en) 2022-04-19 2022-06-01 Union Therapeutics As Treatment of neutrophilic dermatoses
GB202306662D0 (en) 2023-05-05 2023-06-21 Union Therapeutics As Dosage regimen
GB202306663D0 (en) 2023-05-05 2023-06-21 Union Therapeutics As Combination therapy

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE325110T1 (de) * 1995-05-19 2006-06-15 Kyowa Hakko Kogyo Kk Sauerstoff enthaltende heterocyclische verbindungen
US6514996B2 (en) * 1995-05-19 2003-02-04 Kyowa Hakko Kogyo Co., Ltd. Derivatives of benzofuran or benzodioxole
DE10205274A1 (de) * 2002-02-08 2003-08-21 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen enthaltend neben Anticholinergika heterocyclische Verbindungen
JPWO2004005276A1 (ja) * 2002-07-03 2005-11-04 協和醗酵工業株式会社 1,3−ベンゾジオキソール−2−スピロシクロアルカン誘導体の製造法
ATE496029T1 (de) * 2006-07-14 2011-02-15 Chiesi Farma Spa Derivate von 1-phenyl-2-pyridinylalkylenalkohole als phosphodiesteraseinhibitoren
JP5342451B2 (ja) * 2006-12-22 2013-11-13 レオ ファーマ アクティーゼルスカブ Pde4阻害剤として有用な置換アセトフェノン
UA98639C2 (en) * 2007-02-28 2012-06-11 Лео Фарма А/С Phosphodiesterase inhibitors
MY150075A (en) * 2007-02-28 2013-11-29 Leo Pharma As Novel phosphodiesterase inhibitors
CN102958937B (zh) * 2010-06-24 2016-03-30 利奥制药有限公司 作为磷酸二酯酶抑制剂的苯并二氧杂环戊烯或苯并二氧杂环庚烯杂环化合物
WO2014096018A1 (en) * 2012-12-19 2014-06-26 Leo Pharma A/S Methods for the preparation of substituted acetophenones
PT3390407T (pt) * 2015-12-18 2023-11-03 Union Therapeutics As Métodos para a preparação de compostos heterocíclicos de 1,3-benzodioxole

Also Published As

Publication number Publication date
US9908894B2 (en) 2018-03-06
WO2015197534A3 (en) 2016-03-17
KR20170016894A (ko) 2017-02-14
IL249336A0 (en) 2017-02-28
CN106459081A (zh) 2017-02-22
AU2015279428B2 (en) 2018-02-15
PT3157930T (pt) 2018-12-24
TW201613934A (en) 2016-04-16
RU2017101808A (ru) 2018-07-27
CA2953284A1 (en) 2015-12-30
EP3157930A2 (en) 2017-04-26
RU2697251C2 (ru) 2019-08-13
EP3157930B1 (en) 2018-10-17
BR112016029510A2 (pt) 2017-08-22
MX2016016378A (es) 2017-10-16
AU2015279428A1 (en) 2017-01-05
JP6785666B2 (ja) 2020-11-18
RU2017101808A3 (show.php) 2019-01-22
DK3157930T3 (en) 2019-01-21
WO2015197534A2 (en) 2015-12-30
ZA201608442B (en) 2018-05-30
JP2017520547A (ja) 2017-07-27
ES2702451T3 (es) 2019-03-01
CN106459081B (zh) 2019-09-10
US20170137438A1 (en) 2017-05-18

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