PL315666A1 - Heterocyclic compounds of therapeutic properties - Google Patents

Heterocyclic compounds of therapeutic properties

Info

Publication number
PL315666A1
PL315666A1 PL95315666A PL31566695A PL315666A1 PL 315666 A1 PL315666 A1 PL 315666A1 PL 95315666 A PL95315666 A PL 95315666A PL 31566695 A PL31566695 A PL 31566695A PL 315666 A1 PL315666 A1 PL 315666A1
Authority
PL
Poland
Prior art keywords
heterocyclic compounds
therapeutic properties
therapeutic
properties
heterocyclic
Prior art date
Application number
PL95315666A
Other languages
English (en)
Inventor
Robert Charles Glen
David Lawrence Selwood
Graeme Richard Martin
Christopher James Foster
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of PL315666A1 publication Critical patent/PL315666A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
PL95315666A 1994-01-26 1995-01-25 Heterocyclic compounds of therapeutic properties PL315666A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9401436A GB9401436D0 (en) 1994-01-26 1994-01-26 Therapeutic heterocyclic compounds
PCT/GB1995/000142 WO1995020588A1 (en) 1994-01-26 1995-01-25 Indole derivatives as 5-ht1 agonists

Publications (1)

Publication Number Publication Date
PL315666A1 true PL315666A1 (en) 1996-11-25

Family

ID=10749321

Family Applications (1)

Application Number Title Priority Date Filing Date
PL95315666A PL315666A1 (en) 1994-01-26 1995-01-25 Heterocyclic compounds of therapeutic properties

Country Status (26)

Country Link
US (3) US5744466A (xx)
EP (1) EP0741725A1 (xx)
JP (1) JPH09512248A (xx)
CN (1) CN1143960A (xx)
AP (1) AP632A (xx)
AU (2) AU689195B2 (xx)
BG (1) BG100747A (xx)
BR (1) BR9506581A (xx)
CA (1) CA2181475A1 (xx)
CZ (1) CZ216996A3 (xx)
EE (1) EE9600095A (xx)
FI (1) FI962969A0 (xx)
GB (1) GB9401436D0 (xx)
HU (1) HUT76288A (xx)
IL (1) IL112443A (xx)
MX (1) MX9602979A (xx)
NO (1) NO963117L (xx)
NZ (1) NZ278644A (xx)
OA (1) OA10307A (xx)
PL (1) PL315666A1 (xx)
SG (1) SG44926A1 (xx)
SK (1) SK96796A3 (xx)
TW (1) TW377344B (xx)
WO (1) WO1995020588A1 (xx)
YU (1) YU4795A (xx)
ZA (1) ZA95601B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6376463B1 (en) * 1992-04-07 2002-04-23 Emory University Modified factor VIII
GB9515060D0 (en) * 1995-07-22 1995-09-20 Wellcome Found Therapeutic heterocyclic compounds
GB9515305D0 (en) * 1995-07-26 1995-09-20 Wellcome Found Therapeutic heterocyclic compounds
US6909005B1 (en) 1995-08-07 2005-06-21 Astrazeneca Uk Limited One post synthesis of 2-oxazolidinone derivatives
GB9516145D0 (en) * 1995-08-07 1995-10-04 Wellcome Found Improved chemical synthesis
GB9516143D0 (en) * 1995-08-07 1995-10-04 Wellcome Found Improved chemical synthesis
AU2104097A (en) * 1996-03-13 1997-10-01 Glaxo Group Limited Medicaments comprising 5ht1-like receptor agonists with an increased absorption
US5654431A (en) * 1996-05-30 1997-08-05 Meng; Qingchang 5-alkoxy tryptamine derivatives
EP1103552A4 (en) * 1998-08-07 2003-01-15 Takeda Chemical Industries Ltd BENZOTHIEPINE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE
US6245799B1 (en) 1999-11-08 2001-06-12 American Home Products Corp [(Indol-3-yl)-cycloalkyl]-3-substituted azetidines for the treatment of central nervous system disorders
JP2003513970A (ja) * 1999-11-08 2003-04-15 ワイス 中枢神経系障害の治療のための[(インドール−3−イル)−シクロアルキル]−3−置換アゼチジン
WO2001070687A1 (de) * 2000-03-23 2001-09-27 Bayer Aktiengesellschaft Indole zur behandlung von krankheiten die mit schilddrüsenhormonen behandeln werden können
US6462234B2 (en) * 2000-09-18 2002-10-08 Pharmacia & Upjohn Company Process to prepare (2S)-2-(dipropylamino)-6-ethoxy-2, 3-dihydro-1H-indene-5-carboxamide
WO2002051805A1 (de) 2000-12-27 2002-07-04 Bayer Aktiengesellschaft Indol-derivate
EP1888523B1 (en) * 2005-06-03 2011-10-26 Abbott Laboratories Cyclobutyl amine derivatives
EP2049472B1 (en) 2006-06-23 2015-01-21 AbbVie Bahamas Ltd. Cyclopropyl amine derivatives as histamin h3 receptor modulators
US9108948B2 (en) 2006-06-23 2015-08-18 Abbvie Inc. Cyclopropyl amine derivatives
US9186353B2 (en) 2009-04-27 2015-11-17 Abbvie Inc. Treatment of osteoarthritis pain
CN105189511B (zh) 2013-03-13 2017-05-24 百时美施贵宝公司 人免疫缺陷病毒复制的抑制剂
WO2021004516A1 (en) * 2019-07-11 2021-01-14 Ascentage Pharma (Suzhou) Co., Ltd. Method for preparing 2-indolinospirone compound and intermediate thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
GB8724912D0 (en) * 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
IL92096A0 (en) * 1988-10-25 1990-07-12 Abbott Lab Carboxylic nucleoside analogs
US4988703A (en) * 1989-05-22 1991-01-29 Abbott Laboratories Carbocyclic nucleoside analogs with antiviral activity
NZ238424A (en) * 1990-06-07 1993-12-23 Wellcome Found 3,5-substituted indole derivatives; medicaments and preparatory processes.
AU672802B2 (en) * 1992-07-24 1996-10-17 Merck Sharp & Dohme Limited Imidazole, triazole and tetrazole derivatives

Also Published As

Publication number Publication date
IL112443A (en) 1998-12-27
CZ216996A3 (en) 1997-06-11
GB9401436D0 (en) 1994-03-23
AU689195B2 (en) 1998-03-26
AU6348998A (en) 1998-06-18
HU9602035D0 (en) 1996-09-30
MX9602979A (es) 1998-01-31
ZA95601B (en) 1996-07-25
CA2181475A1 (en) 1995-08-03
US6103752A (en) 2000-08-15
SG44926A1 (en) 1997-12-19
US5922748A (en) 1999-07-13
WO1995020588A1 (en) 1995-08-03
SK96796A3 (en) 1997-06-04
AU1462095A (en) 1995-08-15
NO963117D0 (no) 1996-07-25
TW377344B (en) 1999-12-21
HUT76288A (en) 1997-07-28
OA10307A (en) 1997-10-07
AP632A (en) 1998-03-30
US5744466A (en) 1998-04-28
BR9506581A (pt) 1997-09-23
FI962969A (fi) 1996-07-25
NZ278644A (en) 1998-02-26
BG100747A (en) 1997-03-31
EP0741725A1 (en) 1996-11-13
NO963117L (no) 1996-09-23
FI962969A0 (fi) 1996-07-25
IL112443A0 (en) 1995-03-30
CN1143960A (zh) 1997-02-26
AP9600834A0 (en) 1996-07-31
EE9600095A (et) 1996-12-16
JPH09512248A (ja) 1997-12-09
YU4795A (sh) 1998-12-23

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