PL3144306T3 - Pochodna pirazyny - Google Patents

Pochodna pirazyny

Info

Publication number
PL3144306T3
PL3144306T3 PL15792266T PL15792266T PL3144306T3 PL 3144306 T3 PL3144306 T3 PL 3144306T3 PL 15792266 T PL15792266 T PL 15792266T PL 15792266 T PL15792266 T PL 15792266T PL 3144306 T3 PL3144306 T3 PL 3144306T3
Authority
PL
Poland
Prior art keywords
pyrazine derivative
pyrazine
derivative
Prior art date
Application number
PL15792266T
Other languages
English (en)
Polish (pl)
Inventor
Akinobu MARUYAMA
Susumu Takeuchi
Yoshimasa Takahashi
Original Assignee
Teijin Pharma Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Pharma Limited filed Critical Teijin Pharma Limited
Publication of PL3144306T3 publication Critical patent/PL3144306T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
PL15792266T 2014-05-13 2015-05-12 Pochodna pirazyny PL3144306T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2014099677 2014-05-13
EP15792266.7A EP3144306B1 (en) 2014-05-13 2015-05-12 Pyrazine derivative
PCT/JP2015/063654 WO2015174417A1 (ja) 2014-05-13 2015-05-12 ピラジン誘導体

Publications (1)

Publication Number Publication Date
PL3144306T3 true PL3144306T3 (pl) 2018-04-30

Family

ID=54479954

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15792266T PL3144306T3 (pl) 2014-05-13 2015-05-12 Pochodna pirazyny

Country Status (28)

Country Link
US (1) US9856237B2 (enExample)
EP (1) EP3144306B1 (enExample)
JP (1) JP6173576B2 (enExample)
KR (1) KR20170004998A (enExample)
CN (1) CN106458998A (enExample)
AR (1) AR100403A1 (enExample)
AU (1) AU2015260300A1 (enExample)
CA (1) CA2948797A1 (enExample)
CY (1) CY1119876T1 (enExample)
DK (1) DK3144306T3 (enExample)
ES (1) ES2654434T3 (enExample)
HR (1) HRP20180122T1 (enExample)
HU (1) HUE035728T2 (enExample)
IL (1) IL248900A0 (enExample)
LT (1) LT3144306T (enExample)
ME (1) ME02978B (enExample)
MX (1) MX2016014693A (enExample)
NO (1) NO3144306T3 (enExample)
PH (1) PH12016502223A1 (enExample)
PL (1) PL3144306T3 (enExample)
PT (1) PT3144306T (enExample)
RS (1) RS56837B1 (enExample)
RU (1) RU2016148735A (enExample)
SG (1) SG11201609359WA (enExample)
SI (1) SI3144306T1 (enExample)
SM (1) SMT201800155T1 (enExample)
TW (1) TW201609702A (enExample)
WO (1) WO2015174417A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111943957B (zh) * 2019-05-17 2023-01-06 中国医学科学院药物研究所 喹啉甲酰胺类化合物及其制备方法和用途
CN116496198A (zh) * 2023-06-26 2023-07-28 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 一种4-羟基-2'-(1-苄基-5-硝基吡咯甲叉)-苯甲酰肼衍生物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998034922A1 (en) * 1997-02-05 1998-08-13 Sankyo Company, Limited Prophylactic or therapeutic agent for diabetic complication
JP4397875B2 (ja) * 1997-02-05 2010-01-13 第一三共株式会社 糖尿病合併症予防薬又は治療薬
CN101012193A (zh) * 2003-01-02 2007-08-08 霍夫曼-拉罗奇有限公司 新cb 1受体反激动剂
JP2007145786A (ja) * 2005-11-30 2007-06-14 Toray Ind Inc ピラジン誘導体及びそれを有効成分とする腎炎治療薬
JP5378988B2 (ja) 2007-04-11 2013-12-25 キッセイ薬品工業株式会社 5員環へテロ環誘導体及びその医薬用途
AR081930A1 (es) 2010-06-16 2012-10-31 Ardea Biosciences Inc Compuestos de tioacetato
KR20150082194A (ko) 2012-11-14 2015-07-15 데이진 화-마 가부시키가이샤 피리딘 유도체

Also Published As

Publication number Publication date
KR20170004998A (ko) 2017-01-11
IL248900A0 (en) 2017-01-31
EP3144306B1 (en) 2017-11-15
ME02978B (me) 2018-10-20
AR100403A1 (es) 2016-10-05
WO2015174417A1 (ja) 2015-11-19
AU2015260300A1 (en) 2016-12-22
SG11201609359WA (en) 2016-12-29
PT3144306T (pt) 2018-01-08
HUE035728T2 (en) 2018-05-28
JP6173576B2 (ja) 2017-08-02
JPWO2015174417A1 (ja) 2017-04-20
MX2016014693A (es) 2017-02-23
US9856237B2 (en) 2018-01-02
EP3144306A1 (en) 2017-03-22
EP3144306A4 (en) 2017-03-22
CA2948797A1 (en) 2015-11-19
LT3144306T (lt) 2018-01-10
PH12016502223A1 (en) 2017-02-06
DK3144306T3 (en) 2018-01-02
TW201609702A (zh) 2016-03-16
RS56837B1 (sr) 2018-04-30
CN106458998A (zh) 2017-02-22
HRP20180122T1 (hr) 2018-02-23
SI3144306T1 (en) 2018-02-28
ES2654434T3 (es) 2018-02-13
CY1119876T1 (el) 2018-06-27
RU2016148735A (ru) 2018-06-19
RU2016148735A3 (enExample) 2018-06-19
SMT201800155T1 (it) 2018-05-02
US20170152242A1 (en) 2017-06-01
NO3144306T3 (enExample) 2018-04-14

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