PL311198A1 - Method of obtaining detecting presence of polypeptide and method of converting polypeptide - Google Patents

Method of obtaining detecting presence of polypeptide and method of converting polypeptide

Info

Publication number
PL311198A1
PL311198A1 PL94311198A PL31119894A PL311198A1 PL 311198 A1 PL311198 A1 PL 311198A1 PL 94311198 A PL94311198 A PL 94311198A PL 31119894 A PL31119894 A PL 31119894A PL 311198 A1 PL311198 A1 PL 311198A1
Authority
PL
Poland
Prior art keywords
polypeptide
detecting presence
converting
obtaining detecting
obtaining
Prior art date
Application number
PL94311198A
Other languages
English (en)
Inventor
Hans Holmegaard Sorensen
Thorkild Christensen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of PL311198A1 publication Critical patent/PL311198A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575Hormones
    • G01N2333/61Growth hormones [GH] (Somatotropin)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL94311198A 1993-04-20 1994-04-19 Method of obtaining detecting presence of polypeptide and method of converting polypeptide PL311198A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK93445A DK44593D0 (da) 1993-04-20 1993-04-20 Fremgangsmaade til fremstilling af et polypeptid
PCT/DK1994/000157 WO1994024157A1 (en) 1993-04-20 1994-04-19 A method of detecting the presence of and converting of a polypeptide

Publications (1)

Publication Number Publication Date
PL311198A1 true PL311198A1 (en) 1996-02-05

Family

ID=8093625

Family Applications (1)

Application Number Title Priority Date Filing Date
PL94311198A PL311198A1 (en) 1993-04-20 1994-04-19 Method of obtaining detecting presence of polypeptide and method of converting polypeptide

Country Status (14)

Country Link
EP (1) EP0695310A1 (da)
JP (1) JPH08508735A (da)
KR (1) KR960701891A (da)
AU (1) AU6535594A (da)
BG (1) BG100068A (da)
CA (1) CA2160663A1 (da)
CZ (1) CZ272895A3 (da)
DK (1) DK44593D0 (da)
FI (1) FI955000A0 (da)
HU (1) HUT73320A (da)
IL (1) IL109347A0 (da)
NO (1) NO954181L (da)
PL (1) PL311198A1 (da)
WO (1) WO1994024157A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9802454D0 (sv) * 1998-07-08 1998-07-08 Pharmacia & Upjohn Ab Production of peptides
CN1697839B (zh) * 2002-08-28 2010-10-27 法玛西亚公司 同工型杂质水平较低的生长激素及其拮抗剂的制备方法
US20040048315A1 (en) 2002-08-28 2004-03-11 Pharmacia Corporation Method for the preparation of growth hormone and antagonist thereof having lower levels of isoform impurities thereof
HK1079798B (zh) * 2002-09-20 2010-11-19 法玛西亚公司 降低peg化蛋白的聚集体水平的方法
US7470779B2 (en) * 2002-09-20 2008-12-30 Pfizer Inc. Process for decreasing aggregate levels of pegylated protein
ATE463503T1 (de) 2004-12-29 2010-04-15 Novo Nordisk Healthcare Ag Verfahren zur verhinderung der bildung von trisulfidderivaten von polypeptiden
EP2483289B2 (en) 2009-10-02 2025-03-26 Biogen MA Inc. Methods of preventing and removing trisulfide bonds
US9562252B2 (en) 2011-05-13 2017-02-07 Biogen Ma Inc. Methods of preventing and removing trisulfide bonds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4985544A (en) * 1987-08-04 1991-01-15 Kyowa Hakko Kogyo Co., Ltd. Process for renaturing fish growth hormone
US5079230A (en) * 1988-09-12 1992-01-07 Pitman-Moore, Inc. Stable bioactive somatotropins
ES2119779T3 (es) * 1990-09-05 1998-10-16 Southern Cross Biotech Pty Ltd Solubilizacion de proteinas en formas activas.
US5151501A (en) * 1991-12-20 1992-09-29 American Cyanamid Company Method for solubilization and naturation of somatotropins utilizing sulfolane

Also Published As

Publication number Publication date
JPH08508735A (ja) 1996-09-17
HU9503020D0 (en) 1995-12-28
CZ272895A3 (en) 1996-03-13
FI955000L (fi) 1995-10-19
WO1994024157A1 (en) 1994-10-27
NO954181D0 (no) 1995-10-19
CA2160663A1 (en) 1994-10-27
AU6535594A (en) 1994-11-08
EP0695310A1 (en) 1996-02-07
NO954181L (no) 1995-10-19
IL109347A0 (en) 1994-07-31
DK44593D0 (da) 1993-04-20
FI955000A7 (fi) 1995-10-19
FI955000A0 (fi) 1995-10-19
KR960701891A (ko) 1996-03-28
HUT73320A (en) 1996-07-29
BG100068A (bg) 1996-12-31

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