PL3105243T3 - Pochodne 2',3'-dideoksy-5-fluorourydyny, sposób ich wytwarzania i zastosowanie - Google Patents
Pochodne 2',3'-dideoksy-5-fluorourydyny, sposób ich wytwarzania i zastosowanieInfo
- Publication number
- PL3105243T3 PL3105243T3 PL14716996T PL14716996T PL3105243T3 PL 3105243 T3 PL3105243 T3 PL 3105243T3 PL 14716996 T PL14716996 T PL 14716996T PL 14716996 T PL14716996 T PL 14716996T PL 3105243 T3 PL3105243 T3 PL 3105243T3
- Authority
- PL
- Poland
- Prior art keywords
- dideoxy
- manufacture
- application
- fluorouridine derivatives
- fluorouridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C07D453/04—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems having a quinolyl-4, a substituted quinolyl-4 or a alkylenedioxy-quinolyl-4 radical linked through only one carbon atom, attached in position 2, e.g. quinine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL407152A PL225348B1 (pl) | 2014-02-12 | 2014-02-12 | Pochodne 2’,3’-dideoksy-5-fluorourydyny, sposób ich wytwarzania i zastosowanie |
EP14716996.5A EP3105243B1 (en) | 2014-02-12 | 2014-03-04 | 2',3'-dideoxy-5-fluorouridine derivatives, a process for the manufacture thereof and application thereof |
PCT/PL2014/050009 WO2015050467A1 (en) | 2014-02-12 | 2014-03-04 | 2',3'-dideoxy-5-fluorouridine derivatives, a process for the manufacture thereof and application thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3105243T3 true PL3105243T3 (pl) | 2018-08-31 |
Family
ID=50478926
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL407152A PL225348B1 (pl) | 2014-02-12 | 2014-02-12 | Pochodne 2’,3’-dideoksy-5-fluorourydyny, sposób ich wytwarzania i zastosowanie |
PL14716996T PL3105243T3 (pl) | 2014-02-12 | 2014-03-04 | Pochodne 2',3'-dideoksy-5-fluorourydyny, sposób ich wytwarzania i zastosowanie |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL407152A PL225348B1 (pl) | 2014-02-12 | 2014-02-12 | Pochodne 2’,3’-dideoksy-5-fluorourydyny, sposób ich wytwarzania i zastosowanie |
Country Status (7)
Country | Link |
---|---|
US (1) | US9388209B2 (pl) |
EP (1) | EP3105243B1 (pl) |
JP (1) | JP5894350B2 (pl) |
CN (1) | CN104829670A (pl) |
CA (1) | CA2887039C (pl) |
PL (2) | PL225348B1 (pl) |
WO (1) | WO2015050467A1 (pl) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3079668A1 (en) | 2013-12-09 | 2016-10-19 | Durect Corporation | Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same |
CN109942547B (zh) * | 2019-05-06 | 2021-08-27 | 河南师范大学 | 具有生物活性的新型喹啉取代三氮唑类化合物及其合成方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2587647B2 (ja) * | 1987-09-07 | 1997-03-05 | 大鵬薬品工業株式会社 | 3′−置換トリアゾール−2′,3′−ジデオキシ−5−置換ピリミジンヌクレオシド誘導体 |
TWI298067B (en) | 2002-01-31 | 2008-06-21 | Daiso Co Ltd | New optically active compound, method for kinetic resolution of carbonic acid derivatives and catalyst thereof |
CN102617676B (zh) * | 2012-02-24 | 2014-10-29 | 华中科技大学 | 齐多夫定喹啉共轭化合物及其制备方法和抗肝癌之应用 |
-
2014
- 2014-02-12 PL PL407152A patent/PL225348B1/pl unknown
- 2014-03-04 US US14/413,560 patent/US9388209B2/en active Active
- 2014-03-04 EP EP14716996.5A patent/EP3105243B1/en not_active Not-in-force
- 2014-03-04 WO PCT/PL2014/050009 patent/WO2015050467A1/en active Application Filing
- 2014-03-04 PL PL14716996T patent/PL3105243T3/pl unknown
- 2014-03-04 JP JP2015544027A patent/JP5894350B2/ja not_active Expired - Fee Related
- 2014-03-04 CA CA2887039A patent/CA2887039C/en not_active Expired - Fee Related
- 2014-11-04 CN CN201410614221.8A patent/CN104829670A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2887039C (en) | 2016-01-05 |
CA2887039A1 (en) | 2015-04-09 |
JP2016500100A (ja) | 2016-01-07 |
US20160152655A1 (en) | 2016-06-02 |
EP3105243B1 (en) | 2018-02-21 |
US9388209B2 (en) | 2016-07-12 |
PL225348B1 (pl) | 2017-03-31 |
CN104829670A (zh) | 2015-08-12 |
PL407152A1 (pl) | 2014-09-01 |
WO2015050467A1 (en) | 2015-04-09 |
JP5894350B2 (ja) | 2016-03-30 |
EP3105243A1 (en) | 2016-12-21 |
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