PL3066065T3 - Katalityczne uwodornienie do otrzymywania amin z amidów kwasów karboksylowych, diamidów kwasów karboksylowych, di-, tri- lub polipeptydów lub amidów peptydowych - Google Patents
Katalityczne uwodornienie do otrzymywania amin z amidów kwasów karboksylowych, diamidów kwasów karboksylowych, di-, tri- lub polipeptydów lub amidów peptydowychInfo
- Publication number
- PL3066065T3 PL3066065T3 PL14787135T PL14787135T PL3066065T3 PL 3066065 T3 PL3066065 T3 PL 3066065T3 PL 14787135 T PL14787135 T PL 14787135T PL 14787135 T PL14787135 T PL 14787135T PL 3066065 T3 PL3066065 T3 PL 3066065T3
- Authority
- PL
- Poland
- Prior art keywords
- carboxylic acid
- acid amides
- amides
- polypeptides
- amines
- Prior art date
Links
- 150000001732 carboxylic acid derivatives Chemical class 0.000 title 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 2
- 150000001408 amides Chemical class 0.000 title 1
- 150000001412 amines Chemical class 0.000 title 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
- C07C209/50—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B43/00—Formation or introduction of functional groups containing nitrogen
- C07B43/04—Formation or introduction of functional groups containing nitrogen of amino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4062—Esters of acids containing the structure -C(=X)-P(=X)(XR)2 or NC-P(=X)(XR)2, (X = O, S, Se)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyrrole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20130191503 EP2868643A1 (de) | 2013-11-05 | 2013-11-05 | Katalytische Hydrierung zur Herstellung von Aminen aus Carbonsäureamiden, Carbonsäurediamiden, Di-, Tri- oder Polypeptiden oder Peptidamiden |
| EP14787135.4A EP3066065B1 (de) | 2013-11-05 | 2014-10-16 | Katalytische hydrierung zur herstellung von aminen aus carbonsäureamiden, carbonsäurediamiden, di-, tri- oder polypeptiden oder peptidamiden |
| PCT/EP2014/072184 WO2015067450A1 (de) | 2013-11-05 | 2014-10-16 | Katalytische hydrierung zur herstellung von aminen aus carbonsäureamiden, carbonsäurediamiden, di-, tri- oder polypeptiden oder peptidamiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3066065T3 true PL3066065T3 (pl) | 2019-11-29 |
Family
ID=49554033
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14787135T PL3066065T3 (pl) | 2013-11-05 | 2014-10-16 | Katalityczne uwodornienie do otrzymywania amin z amidów kwasów karboksylowych, diamidów kwasów karboksylowych, di-, tri- lub polipeptydów lub amidów peptydowych |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9878975B2 (pl) |
| EP (2) | EP2868643A1 (pl) |
| JP (1) | JP6645974B2 (pl) |
| CN (1) | CN105873884B (pl) |
| ES (1) | ES2744849T3 (pl) |
| HR (1) | HRP20191598T1 (pl) |
| HU (1) | HUE045105T2 (pl) |
| PL (1) | PL3066065T3 (pl) |
| PT (1) | PT3066065T (pl) |
| SI (1) | SI3066065T1 (pl) |
| WO (1) | WO2015067450A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2868652A1 (de) | 2013-11-05 | 2015-05-06 | Evonik Industries AG | Katalytische Hydrierung zur Herstellung von Aminen aus Amidacetalen, Keten-N,O-acetalen oder Esterimiden |
| EP3202758A1 (de) | 2016-02-03 | 2017-08-09 | Evonik Degussa GmbH | Reduktive alkylierung von aminen mit orthocarbonsäureestern |
| AR121715A1 (es) | 2020-04-03 | 2022-06-29 | Biocryst Pharm Inc | Pirrolopirimidinaminas como inhibidores del sistema del complemento |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE604277C (de) | 1933-03-17 | 1934-10-18 | Kohlentechnik M B H Ges | Verfahren zur Herstellung der Hydrochloride von Aminen oder Aminosaeureestern |
| JPS5132602B2 (pl) * | 1972-04-03 | 1976-09-14 | ||
| DE2453055C3 (de) | 1974-11-08 | 1979-03-08 | Hoechst Ag, 6000 Frankfurt | Verfahren zur Herstellung von 1,2,4-Triaminobenzolen |
| FR2633927B1 (fr) * | 1988-07-08 | 1991-06-07 | Ceca Sa | Procede perfectionne pour l'obtention de n,n-dimethyl-alkylamines par hydrogenation catalytique de n,n-dimethyl-alkylamides |
| JPH08245524A (ja) * | 1995-03-10 | 1996-09-24 | Sagami Chem Res Center | アミン類の製造方法 |
| MY145824A (en) * | 2006-03-08 | 2012-04-30 | Kao Corp | Method for producing nitrogen-containing compound |
| TW200837045A (en) * | 2006-09-22 | 2008-09-16 | Lucite Int Uk Ltd | Production of amines |
| JP5196922B2 (ja) * | 2007-09-07 | 2013-05-15 | 花王株式会社 | 含窒素化合物の製造方法 |
| US9290441B2 (en) * | 2007-10-30 | 2016-03-22 | Yeda Research And Development Co. Ltd. | Use of ruthenium complexes for formation and/or hydrogenation of amides and related carboxylic acid derivatives |
| JP5720256B2 (ja) * | 2011-01-13 | 2015-05-20 | 宇部興産株式会社 | アミド基還元用触媒および該触媒を用いたアミノメチル化合物の製造方法 |
| EP2868652A1 (de) | 2013-11-05 | 2015-05-06 | Evonik Industries AG | Katalytische Hydrierung zur Herstellung von Aminen aus Amidacetalen, Keten-N,O-acetalen oder Esterimiden |
-
2013
- 2013-11-05 EP EP20130191503 patent/EP2868643A1/de not_active Withdrawn
-
2014
- 2014-10-16 US US15/034,120 patent/US9878975B2/en not_active Expired - Fee Related
- 2014-10-16 SI SI201431329T patent/SI3066065T1/sl unknown
- 2014-10-16 HR HRP20191598 patent/HRP20191598T1/hr unknown
- 2014-10-16 PL PL14787135T patent/PL3066065T3/pl unknown
- 2014-10-16 JP JP2016550970A patent/JP6645974B2/ja not_active Expired - Fee Related
- 2014-10-16 EP EP14787135.4A patent/EP3066065B1/de active Active
- 2014-10-16 CN CN201480072289.6A patent/CN105873884B/zh not_active Expired - Fee Related
- 2014-10-16 ES ES14787135T patent/ES2744849T3/es active Active
- 2014-10-16 WO PCT/EP2014/072184 patent/WO2015067450A1/de not_active Ceased
- 2014-10-16 PT PT14787135T patent/PT3066065T/pt unknown
- 2014-10-16 HU HUE14787135A patent/HUE045105T2/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN105873884B (zh) | 2017-09-26 |
| PT3066065T (pt) | 2019-09-20 |
| WO2015067450A1 (de) | 2015-05-14 |
| SI3066065T1 (sl) | 2019-10-30 |
| EP3066065A1 (de) | 2016-09-14 |
| EP3066065B1 (de) | 2019-06-19 |
| CN105873884A (zh) | 2016-08-17 |
| US9878975B2 (en) | 2018-01-30 |
| US20160272571A1 (en) | 2016-09-22 |
| HRP20191598T1 (hr) | 2019-11-29 |
| JP2016536359A (ja) | 2016-11-24 |
| ES2744849T3 (es) | 2020-02-26 |
| JP6645974B2 (ja) | 2020-02-14 |
| HUE045105T2 (hu) | 2019-12-30 |
| EP2868643A1 (de) | 2015-05-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SG11201502812WA (en) | NOVEL α4ß7 PEPTIDE DIMER ANTAGONISTS | |
| SG11201507527WA (en) | Solid phase peptide synthesis processes and associated systems | |
| EP2981543A4 (en) | Novel 4 7 peptide antagonists | |
| SG11201505924TA (en) | Factor viii polypeptide formulations | |
| SG11201600473UA (en) | Amino acid derivatives | |
| SG10201606044VA (en) | Head support for stopping airway disorders | |
| ZA201708157B (en) | Cyclopropane carboxylic acid derivatives and pharmaceutical uses thereof | |
| SE1700296A1 (en) | Supports for membrane enhanced peptide synthesis | |
| IL247099A0 (en) | Beta-converted amino acids and their analogs, preparations containing them and their uses | |
| FR3004128B1 (fr) | Tete de pulverisation amelioree. | |
| GB2542401B (en) | Modified spray head | |
| ZA201504986B (en) | Peptide | |
| PT3061771T (pt) | Novo péptido unido a quatro epitopos ctl | |
| PT3066065T (pt) | Hidrogenação catalítica para a preparação de aminas a partir de amidas de ácido carboxílico, diamidas de ácido carboxílico, di-, tri- ou polipéptidos ou amidas peptídicas | |
| IL245224A0 (en) | sprinkler head | |
| ZA201504987B (en) | Peptide | |
| GB2542399B (en) | Modified spray head | |
| IL243730B (en) | Vasopressin-2 receptor agonist peptides | |
| PL2951143T3 (pl) | Sposób karbonylowania olefin | |
| TWM476732U (en) | Improved structure for steering head joint set | |
| SG11201702771UA (en) | Catalyst for the gas phase production of carboxylic acids | |
| GB2510929B (en) | Spray apparatus | |
| GB201303394D0 (en) | Apparatus for assisting the upstream movement of anguillidae | |
| GB201317009D0 (en) | Ultrasonic spray system | |
| GB201314300D0 (en) | Improved system for the capture of acid gases |