PL2975030T3 - Pochodna dihydropirydazyno-3,5-dionu - Google Patents

Pochodna dihydropirydazyno-3,5-dionu

Info

Publication number
PL2975030T3
PL2975030T3 PL14765619T PL14765619T PL2975030T3 PL 2975030 T3 PL2975030 T3 PL 2975030T3 PL 14765619 T PL14765619 T PL 14765619T PL 14765619 T PL14765619 T PL 14765619T PL 2975030 T3 PL2975030 T3 PL 2975030T3
Authority
PL
Poland
Prior art keywords
dihydropyridazine
dione derivative
dione
derivative
Prior art date
Application number
PL14765619T
Other languages
English (en)
Polish (pl)
Inventor
Yoshihito Ohtake
Naoki Okamoto
Yoshiyuki Ono
Hirotaka Kashiwagi
Atsushi KIMBARA
Takeo Harada
Nobuyuki Hori
Yoshihisa Murata
Kazutaka Tachibana
Shota Tanaka
Kenichi Nomura
Mitsuaki IDE
Eisaku Mizuguchi
Yasuhiro ICHIDA
Shuichi OHTOMO
Naoshi Horiba
Original Assignee
Chugai Seiyaku Kabushiki Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Seiyaku Kabushiki Kaisha filed Critical Chugai Seiyaku Kabushiki Kaisha
Publication of PL2975030T3 publication Critical patent/PL2975030T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/501Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/5025Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/504Pyridazines; Hydrogenated pyridazines forming part of bridged ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/18Drugs for disorders of the endocrine system of the parathyroid hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/18Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Luminescent Compositions (AREA)
PL14765619T 2013-03-13 2014-03-13 Pochodna dihydropirydazyno-3,5-dionu PL2975030T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2013051082 2013-03-13
JP2013132889 2013-06-25
EP14765619.3A EP2975030B1 (en) 2013-03-13 2014-03-13 Dihydropyridazine-3,5-dione derivative
PCT/JP2014/056778 WO2014142273A1 (ja) 2013-03-13 2014-03-13 ジヒドロピリダジン-3,5-ジオン誘導体

Publications (1)

Publication Number Publication Date
PL2975030T3 true PL2975030T3 (pl) 2021-01-11

Family

ID=51536921

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14765619T PL2975030T3 (pl) 2013-03-13 2014-03-13 Pochodna dihydropirydazyno-3,5-dionu

Country Status (29)

Country Link
EP (2) EP3757093A1 (cg-RX-API-DMAC7.html)
JP (2) JP5814488B2 (cg-RX-API-DMAC7.html)
KR (2) KR102072268B1 (cg-RX-API-DMAC7.html)
CN (1) CN105073715B (cg-RX-API-DMAC7.html)
AU (1) AU2014230552B2 (cg-RX-API-DMAC7.html)
BR (1) BR112015022092B1 (cg-RX-API-DMAC7.html)
CA (1) CA2901868C (cg-RX-API-DMAC7.html)
CL (1) CL2015002543A1 (cg-RX-API-DMAC7.html)
CR (1) CR20150505A (cg-RX-API-DMAC7.html)
DK (1) DK2975030T3 (cg-RX-API-DMAC7.html)
ES (1) ES2811126T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20201211T1 (cg-RX-API-DMAC7.html)
HU (1) HUE050577T2 (cg-RX-API-DMAC7.html)
IL (1) IL240825B (cg-RX-API-DMAC7.html)
LT (1) LT2975030T (cg-RX-API-DMAC7.html)
MX (1) MX376532B (cg-RX-API-DMAC7.html)
MY (1) MY174269A (cg-RX-API-DMAC7.html)
NZ (1) NZ711182A (cg-RX-API-DMAC7.html)
PE (1) PE20151535A1 (cg-RX-API-DMAC7.html)
PH (1) PH12015501940A1 (cg-RX-API-DMAC7.html)
PL (1) PL2975030T3 (cg-RX-API-DMAC7.html)
PT (1) PT2975030T (cg-RX-API-DMAC7.html)
RS (1) RS60911B1 (cg-RX-API-DMAC7.html)
RU (1) RU2662832C2 (cg-RX-API-DMAC7.html)
SG (1) SG11201507345RA (cg-RX-API-DMAC7.html)
SI (1) SI2975030T1 (cg-RX-API-DMAC7.html)
TW (2) TWI596095B (cg-RX-API-DMAC7.html)
UA (1) UA118755C2 (cg-RX-API-DMAC7.html)
WO (1) WO2014142273A1 (cg-RX-API-DMAC7.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY174269A (en) * 2013-03-13 2020-04-01 Chugai Pharmaceutical Co Ltd Dihydropyridazine-3,5-dione derivative
MX383069B (es) * 2014-09-12 2025-03-13 Chugai Pharmaceutical Co Ltd Farmaceutico que contiene inhibidor de transportador de fosfato dependiente de sodio.
WO2018019721A1 (en) 2016-07-26 2018-02-01 Basf Se Herbicidal pyridine compounds
WO2018019755A1 (en) 2016-07-26 2018-02-01 Basf Se Herbicidal pyridine compounds
CN110885290A (zh) * 2019-12-16 2020-03-17 阿里生物新材料(常州)有限公司 一种3-氟-2-甲基-4-三氟甲基苯胺盐酸盐的合成方法
CN115734965B (zh) * 2020-06-26 2025-05-02 日本农药株式会社 芳基四氢哒嗪衍生物或其盐类、和含有该化合物的杀虫剂及其使用方法
WO2022221182A1 (en) * 2021-04-12 2022-10-20 Jnana Therapeutics Inc. Small molecule inhibitors of mammalian slc34a1 function
KR20240018523A (ko) 2021-06-08 2024-02-13 추가이 세이야쿠 가부시키가이샤 다이하이드로피리다진-3,5-다이온 유도체를 함유하는 제제
AR126060A1 (es) 2021-06-08 2023-09-06 Chugai Pharmaceutical Co Ltd Método para producir derivado de dihidropiridazin-3,5-diona
US20250074896A1 (en) * 2021-12-28 2025-03-06 Nihon Nohyaku Co., Ltd. Aryltetrahydropyridazine derivative or salt thereof and insecticidal agent containing the compound and method for using same
JPWO2023219127A1 (cg-RX-API-DMAC7.html) 2022-05-11 2023-11-16
CN116217862A (zh) * 2023-03-21 2023-06-06 中国农业科学院农业环境与可持续发展研究所 一种可降解生物膜助剂的制备方法

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AU2003211381B9 (en) * 2002-02-19 2009-07-30 Ono Pharmaceutical Co., Ltd. Fused pyridazine derivative compounds and drugs containing the compounds as the active ingredient
CN1662529A (zh) * 2002-06-19 2005-08-31 默克专利有限公司 作为磷酸二酯酶iv抑制剂的噻唑衍生物
EP2361905B1 (en) * 2005-05-18 2013-03-06 Array Biopharma Inc. Heterocyclic Inhibitors of MEK and methods of use thereof
GB0610680D0 (en) * 2006-05-31 2006-07-12 Istituto Di Ricerche D Biolog Therapeutic compounds
EA017900B1 (ru) * 2006-11-03 2013-04-30 Басф Се Способ получения дифторметилпиразолилкарбоксилатов
TW201006821A (en) * 2008-07-16 2010-02-16 Bristol Myers Squibb Co Pyridone and pyridazone analogues as GPR119 modulators
EP2334682B1 (en) * 2008-08-20 2017-10-04 Fibrogen, Inc. Pyrrolo [ 1, 2 -b] pyridazine derivatives and their use as hif modulators
WO2011048611A1 (en) * 2009-10-07 2011-04-28 Torrent Pharmaceuticals Limited Novel fused pyridazine derivatives
EP2565190B1 (en) 2010-04-28 2015-06-03 Astellas Pharma Inc. Tetrahydrobenzothiophene compound
WO2012006475A1 (en) 2010-07-07 2012-01-12 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
JP5827327B2 (ja) * 2010-07-07 2015-12-02 アーデリクス,インコーポレーテッド リン酸輸送を阻害する化合物及び方法
ES2585415T3 (es) 2011-10-27 2016-10-05 Astellas Pharma Inc. Derivado de N-tienilbenzamida sustituida con aminoalquilo
MY174269A (en) * 2013-03-13 2020-04-01 Chugai Pharmaceutical Co Ltd Dihydropyridazine-3,5-dione derivative

Also Published As

Publication number Publication date
BR112015022092B1 (pt) 2023-04-11
HRP20201211T1 (hr) 2020-11-13
RU2662832C2 (ru) 2018-07-31
JP5814488B2 (ja) 2015-11-17
RU2015143507A (ru) 2017-04-19
MX376532B (es) 2025-03-07
BR112015022092A2 (pt) 2017-07-18
PH12015501940B1 (en) 2016-01-11
TWI596095B (zh) 2017-08-21
CN105073715A (zh) 2015-11-18
PH12015501940A1 (en) 2016-01-11
MY174269A (en) 2020-04-01
CR20150505A (es) 2015-10-26
DK2975030T3 (da) 2020-08-31
WO2014142273A1 (ja) 2014-09-18
NZ711182A (en) 2020-05-29
JP2016040262A (ja) 2016-03-24
EP2975030B1 (en) 2020-07-15
PE20151535A1 (es) 2015-10-28
CA2901868A1 (en) 2014-09-18
CL2015002543A1 (es) 2016-02-26
JP6420738B2 (ja) 2018-11-07
JPWO2014142273A1 (ja) 2017-02-16
TWI683811B (zh) 2020-02-01
UA118755C2 (uk) 2019-03-11
TW201446756A (zh) 2014-12-16
KR20160119282A (ko) 2016-10-12
KR102072268B1 (ko) 2020-01-31
CA2901868C (en) 2022-05-03
IL240825B (en) 2020-07-30
TW201741304A (zh) 2017-12-01
CN105073715B (zh) 2017-12-01
RS60911B1 (sr) 2020-11-30
LT2975030T (lt) 2020-09-25
AU2014230552A1 (en) 2015-08-13
IL240825A0 (en) 2015-10-29
EP2975030A1 (en) 2016-01-20
KR20150127721A (ko) 2015-11-17
EP3757093A1 (en) 2020-12-30
HK1212700A1 (zh) 2016-06-17
AU2014230552B2 (en) 2017-11-16
SI2975030T1 (sl) 2020-10-30
ES2811126T3 (es) 2021-03-10
KR101664460B1 (ko) 2016-10-10
SG11201507345RA (en) 2015-10-29
PT2975030T (pt) 2020-09-28
BR112015022092A8 (pt) 2018-01-23
HUE050577T2 (hu) 2020-12-28
MX2015012537A (es) 2016-02-10
EP2975030A4 (en) 2016-08-03

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