PL2968483T3 - Podskórne podawanie adamts13 - Google Patents

Podskórne podawanie adamts13

Info

Publication number
PL2968483T3
PL2968483T3 PL14719469T PL14719469T PL2968483T3 PL 2968483 T3 PL2968483 T3 PL 2968483T3 PL 14719469 T PL14719469 T PL 14719469T PL 14719469 T PL14719469 T PL 14719469T PL 2968483 T3 PL2968483 T3 PL 2968483T3
Authority
PL
Poland
Prior art keywords
adamts13
subcutaneous administration
subcutaneous
administration
Prior art date
Application number
PL14719469T
Other languages
English (en)
Inventor
Alexandra Nathalie Kopic
Werner Hoellriegl
Barbara Plaimauer
Hanspeter Rottensteiner
Eva-Maria Muchitsch
Original Assignee
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Publication of PL2968483T3 publication Critical patent/PL2968483T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489Metalloendopeptidases (3.4.24)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24Metalloendopeptidases (3.4.24)
    • C12Y304/24087ADAMTS13 endopeptidase (3.4.24.87)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
PL14719469T 2013-03-15 2014-03-13 Podskórne podawanie adamts13 PL2968483T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361794659P 2013-03-15 2013-03-15
EP14719469.0A EP2968483B1 (en) 2013-03-15 2014-03-13 Subcutaneous administration of adamts13
PCT/US2014/026747 WO2014151968A1 (en) 2013-03-15 2014-03-13 Subcutaneous administration of adamts13

Publications (1)

Publication Number Publication Date
PL2968483T3 true PL2968483T3 (pl) 2022-04-04

Family

ID=50549463

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14719469T PL2968483T3 (pl) 2013-03-15 2014-03-13 Podskórne podawanie adamts13

Country Status (19)

Country Link
US (4) US9611467B2 (pl)
EP (2) EP3960196A1 (pl)
JP (4) JP6484216B2 (pl)
KR (5) KR102513872B1 (pl)
CN (2) CN114259558A (pl)
AU (5) AU2013203062C1 (pl)
BR (1) BR112015023542A8 (pl)
CA (1) CA2905058A1 (pl)
DK (1) DK2968483T3 (pl)
EA (2) EA034546B1 (pl)
ES (1) ES2906550T3 (pl)
HK (1) HK1220131A1 (pl)
IL (3) IL241305B (pl)
MX (2) MX2015012783A (pl)
PL (1) PL2968483T3 (pl)
PT (1) PT2968483T (pl)
SG (3) SG10202001227QA (pl)
TW (4) TWI740207B (pl)
WO (1) WO2014151968A1 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013203062C1 (en) 2013-03-15 2018-06-28 Takeda Pharmaceutical Company Limited Subcutaneous administration of adamts13
GB201510870D0 (en) * 2015-05-26 2015-08-05 Baxalta Inc And Katholieke Universiteit Leuven And Baxalta Gmbh Treatment of infarction
EA201990373A1 (ru) 2016-08-04 2019-07-31 Баксалта Инкорпорэйтед Применение adamts13 для лечения, уменьшения интенсивности и/или предупреждения вазоокклюзивного криза при серповидноклеточной анемии, остром повреждении легкого и/или остром респираторном дистресс-синдроме
WO2020214033A1 (en) * 2019-04-17 2020-10-22 Erasmus University Medical Center Rotterdam Papain-like cysteine peptidase medicaments and uses thereof
CA3173709A1 (en) 2020-04-02 2021-10-07 Friedmund BACHMANN Adamts13 variant, compositions, and uses thereof
US20230201319A1 (en) 2020-05-22 2023-06-29 Takeda Pharmaceutical Company Limited Adamts13 compositions and methods for treating and diagnosing complications of coronavirus disease
KR20220068144A (ko) * 2020-11-18 2022-05-25 주식회사 녹십자 자가 항체에 대한 회피율 또는 활성이 증가된 adamts13 변이체
GB202102208D0 (en) * 2021-02-17 2021-03-31 Univ Manchester Adamts13 variant

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL113010A (en) 1994-03-31 1999-10-28 Pharmacia & Upjohn Ab Pharmaceutical formulation comprising factor viii with an activity of at least 500iu/ml and an enhancer for improved subcutaneous intramuscular or intradermal administration
US6926894B2 (en) 2000-11-22 2005-08-09 Baxter Aktiengesellschaft Composition exhibiting a von willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
US7037658B2 (en) 2001-08-16 2006-05-02 Regents Of University Of Michigan Methods and compositions for detecting variant ADAMTS13 genes
US7763430B2 (en) 2003-04-22 2010-07-27 Baxter International Inc. Diagnostic assay for anti-von Willebrand Factor cleaving protease (ADAMTS13) antibodies
AU2006257073B2 (en) * 2005-06-17 2011-08-04 Children's Medical Center Corporation ADAMTS13-comprising compositions having thrombolytic activity
JP2009539757A (ja) * 2006-06-16 2009-11-19 バクスター・インターナショナル・インコーポレイテッド 血栓溶解活性を有するadamts13含有組成物
WO2009140140A1 (en) 2008-05-12 2009-11-19 Immune Disease Institute Von willebrand factor (vwf) inhibitors for treatment or prevention of infarction
US20120148557A1 (en) * 2009-08-20 2012-06-14 Ulrich Kronthaler Albumin fused coagulation factors for non-intravenous administration in the therapy and prophylactic treatment of bleeding disorders
KR20210054598A (ko) * 2009-09-21 2021-05-13 다케다 야쿠힌 고교 가부시키가이샤 안정화된 액체 및 동결건조된 adamts13 제제
BR112013000515B1 (pt) * 2010-07-08 2021-11-03 Takeda Pharmaceutical Company Limited Método para produzir uma composição de fator von willebrand recombinante (rvwf)
AU2013203062C1 (en) 2013-03-15 2018-06-28 Takeda Pharmaceutical Company Limited Subcutaneous administration of adamts13

Also Published As

Publication number Publication date
IL241305A0 (en) 2015-11-30
NZ712440A (en) 2020-11-27
TW202313664A (zh) 2023-04-01
SG10201707074TA (en) 2017-10-30
NZ749570A (en) 2020-11-27
US10413600B2 (en) 2019-09-17
KR102218489B1 (ko) 2021-02-22
BR112015023542A2 (pt) 2017-07-18
US20140271611A1 (en) 2014-09-18
TW202017591A (zh) 2020-05-16
WO2014151968A8 (en) 2015-10-15
BR112015023542A8 (pt) 2019-12-03
AU2013203062C1 (en) 2018-06-28
EA201591758A1 (ru) 2016-03-31
IL290486A (en) 2022-04-01
KR102513872B1 (ko) 2023-03-27
KR20210021107A (ko) 2021-02-24
AU2016231547B2 (en) 2018-03-15
ES2906550T3 (es) 2022-04-19
US11779635B2 (en) 2023-10-10
EA034546B1 (ru) 2020-02-19
EP2968483B1 (en) 2021-12-01
MX2021002513A (es) 2021-04-28
IL273365B (en) 2022-05-01
SG11201507271QA (en) 2015-10-29
TWI786563B (zh) 2022-12-11
AU2020202738B2 (en) 2022-06-09
AU2022211908A1 (en) 2022-09-01
IL290486B1 (en) 2023-04-01
HK1220131A1 (zh) 2017-04-28
DK2968483T3 (da) 2022-02-14
JP2019142850A (ja) 2019-08-29
TWI690326B (zh) 2020-04-11
EA201992832A1 (ru) 2020-05-31
AU2018203665B2 (en) 2020-01-30
KR20190022926A (ko) 2019-03-06
IL273365A (en) 2020-05-31
AU2020202738A1 (en) 2020-05-14
AU2013203062A1 (en) 2014-10-02
US20220080032A1 (en) 2022-03-17
US20200101144A1 (en) 2020-04-02
KR102365936B1 (ko) 2022-02-23
AU2016231547A1 (en) 2016-10-06
AU2022211908B2 (en) 2023-11-30
CN105407912A (zh) 2016-03-16
KR20220027266A (ko) 2022-03-07
MX2015012783A (es) 2016-04-28
TW202138003A (zh) 2021-10-16
KR102102087B1 (ko) 2020-04-20
KR20160016756A (ko) 2016-02-15
EA201591758A8 (ru) 2017-03-31
TW201513881A (zh) 2015-04-16
US20170224785A1 (en) 2017-08-10
IL290486B2 (en) 2023-08-01
JP6484216B2 (ja) 2019-03-13
PT2968483T (pt) 2022-02-23
JP6998333B2 (ja) 2022-02-10
WO2014151968A1 (en) 2014-09-25
EP2968483A1 (en) 2016-01-20
JP7238088B2 (ja) 2023-03-13
CN114259558A (zh) 2022-04-01
AU2013203062B2 (en) 2016-06-23
JP2022027991A (ja) 2022-02-14
IL241305B (en) 2020-04-30
EP3960196A1 (en) 2022-03-02
TWI740207B (zh) 2021-09-21
CA2905058A1 (en) 2014-09-25
US9611467B2 (en) 2017-04-04
US11185575B2 (en) 2021-11-30
SG10202001227QA (en) 2020-03-30
AU2018203665A1 (en) 2018-06-14
JP2016517421A (ja) 2016-06-16
NZ751610A (en) 2020-11-27
JP2023071821A (ja) 2023-05-23
KR20200041394A (ko) 2020-04-21

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