HK1220131A1 - 的皮下施用 - Google Patents

的皮下施用

Info

Publication number
HK1220131A1
HK1220131A1 HK16108245.8A HK16108245A HK1220131A1 HK 1220131 A1 HK1220131 A1 HK 1220131A1 HK 16108245 A HK16108245 A HK 16108245A HK 1220131 A1 HK1220131 A1 HK 1220131A1
Authority
HK
Hong Kong
Prior art keywords
adamts13
subcutaneous administration
subcutaneous
administration
adamts13 adamts13
Prior art date
Application number
HK16108245.8A
Other languages
English (en)
Inventor
Alexandra Nathalie Schiviz
Werner Hoellriegl
Barbara Plaimauer
Hanspeter Rottensteiner
Eva-Maria Muchitsch
Original Assignee
Baxalta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxalta Inc filed Critical Baxalta Inc
Publication of HK1220131A1 publication Critical patent/HK1220131A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24087—ADAMTS13 endopeptidase (3.4.24.87)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
HK16108245.8A 2013-03-15 2016-07-13 的皮下施用 HK1220131A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361794659P 2013-03-15 2013-03-15
PCT/US2014/026747 WO2014151968A1 (en) 2013-03-15 2014-03-13 Subcutaneous administration of adamts13

Publications (1)

Publication Number Publication Date
HK1220131A1 true HK1220131A1 (zh) 2017-04-28

Family

ID=50549463

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16108245.8A HK1220131A1 (zh) 2013-03-15 2016-07-13 的皮下施用

Country Status (19)

Country Link
US (4) US9611467B2 (zh)
EP (2) EP2968483B1 (zh)
JP (4) JP6484216B2 (zh)
KR (5) KR102102087B1 (zh)
CN (2) CN105407912A (zh)
AU (5) AU2013203062C1 (zh)
BR (1) BR112015023542A8 (zh)
CA (1) CA2905058A1 (zh)
DK (1) DK2968483T3 (zh)
EA (2) EA201992832A1 (zh)
ES (1) ES2906550T3 (zh)
HK (1) HK1220131A1 (zh)
IL (3) IL241305B (zh)
MX (2) MX2015012783A (zh)
PL (1) PL2968483T3 (zh)
PT (1) PT2968483T (zh)
SG (3) SG10201707074TA (zh)
TW (4) TW202313664A (zh)
WO (1) WO2014151968A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013203062C1 (en) 2013-03-15 2018-06-28 Takeda Pharmaceutical Company Limited Subcutaneous administration of adamts13
GB201510870D0 (en) * 2015-05-26 2015-08-05 Baxalta Inc And Katholieke Universiteit Leuven And Baxalta Gmbh Treatment of infarction
KR20230079461A (ko) 2016-08-04 2023-06-07 다케다 파머수티컬 컴패니 리미티드 급성 폐 손상 및/또는 급성 호흡 곤란 증후군에서 혈관폐색 위기의 치료, 개선 및/또는 예방을 위한 adamts13의 용도
WO2020214033A1 (en) * 2019-04-17 2020-10-22 Erasmus University Medical Center Rotterdam Papain-like cysteine peptidase medicaments and uses thereof
BR112022019817A2 (pt) 2020-04-02 2022-12-06 Takeda Pharmaceuticals Co Variante de adamts13, composições e usos das mesmas
US20230201319A1 (en) 2020-05-22 2023-06-29 Takeda Pharmaceutical Company Limited Adamts13 compositions and methods for treating and diagnosing complications of coronavirus disease
EP4249594A1 (en) * 2020-11-18 2023-09-27 Green Cross Corporation Adamts13 variant having increased escaping rate or activity against autoantibody
GB202102208D0 (en) * 2021-02-17 2021-03-31 Univ Manchester Adamts13 variant

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL113010A0 (en) 1994-03-31 1995-10-31 Pharmacia Ab Pharmaceutical formulation comprising factor VIII or factor ix with an activity of at least 200 IU/ml and an enhancer for improved subcutaneous intramuscular or intradermal administration
US6926894B2 (en) 2000-11-22 2005-08-09 Baxter Aktiengesellschaft Composition exhibiting a von willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
WO2003016492A2 (en) * 2001-08-16 2003-02-27 The Regents Of The University Of Michigan Adamts13 genes and proteins and variants, and uses thereof
US7763430B2 (en) 2003-04-22 2010-07-27 Baxter International Inc. Diagnostic assay for anti-von Willebrand Factor cleaving protease (ADAMTS13) antibodies
WO2006133955A1 (en) * 2005-06-17 2006-12-21 Baxter International Inc. Adamts13-comprising compositions having thrombolytic activity
JP2009539757A (ja) * 2006-06-16 2009-11-19 バクスター・インターナショナル・インコーポレイテッド 血栓溶解活性を有するａｄａｍｔｓ１３含有組成物
US20090317375A1 (en) * 2008-05-12 2009-12-24 Immune Disease Institute, Inc. Von willebrand factor (vwf) inhibitors for treatment or prevention of infarction
US20120148557A1 (en) * 2009-08-20 2012-06-14 Ulrich Kronthaler Albumin fused coagulation factors for non-intravenous administration in the therapy and prophylactic treatment of bleeding disorders
EA024267B1 (ru) 2009-09-21 2016-09-30 Баксалта Инкорпорейтид Стабилизированные жидкие и лиофилизированные композиции adamts13
JP6138683B2 (ja) * 2010-07-08 2017-05-31 バクスアルタ ゲーエムベーハー 細胞培養による組換え型ａｄａｍｔｓ１３産生方法
AU2013203062C1 (en) 2013-03-15 2018-06-28 Takeda Pharmaceutical Company Limited Subcutaneous administration of adamts13

Also Published As

Publication number Publication date
DK2968483T3 (da) 2022-02-14
US9611467B2 (en) 2017-04-04
IL290486B2 (en) 2023-08-01
TW202138003A (zh) 2021-10-16
AU2016231547A1 (en) 2016-10-06
KR102102087B1 (ko) 2020-04-20
MX2021002513A (es) 2021-04-28
TW201513881A (zh) 2015-04-16
ES2906550T3 (es) 2022-04-19
TWI740207B (zh) 2021-09-21
NZ749570A (en) 2020-11-27
TW202017591A (zh) 2020-05-16
AU2018203665B2 (en) 2020-01-30
CN114259558A (zh) 2022-04-01
KR20160016756A (ko) 2016-02-15
US20200101144A1 (en) 2020-04-02
IL273365A (en) 2020-05-31
EA201591758A8 (ru) 2017-03-31
AU2016231547B2 (en) 2018-03-15
EA201992832A1 (ru) 2020-05-31
JP2023071821A (ja) 2023-05-23
JP6484216B2 (ja) 2019-03-13
KR20220027266A (ko) 2022-03-07
AU2022211908B2 (en) 2023-11-30
CN105407912A (zh) 2016-03-16
IL241305B (en) 2020-04-30
JP2016517421A (ja) 2016-06-16
AU2020202738A1 (en) 2020-05-14
IL273365B (en) 2022-05-01
TWI786563B (zh) 2022-12-11
SG11201507271QA (en) 2015-10-29
BR112015023542A2 (pt) 2017-07-18
EA034546B1 (ru) 2020-02-19
KR102218489B1 (ko) 2021-02-22
AU2013203062C1 (en) 2018-06-28
EA201591758A1 (ru) 2016-03-31
NZ712440A (en) 2020-11-27
TW202313664A (zh) 2023-04-01
TWI690326B (zh) 2020-04-11
CA2905058A1 (en) 2014-09-25
AU2020202738B2 (en) 2022-06-09
AU2022211908A1 (en) 2022-09-01
EP2968483A1 (en) 2016-01-20
IL290486A (en) 2022-04-01
JP6998333B2 (ja) 2022-02-10
US11779635B2 (en) 2023-10-10
WO2014151968A1 (en) 2014-09-25
BR112015023542A8 (pt) 2019-12-03
KR20190022926A (ko) 2019-03-06
PT2968483T (pt) 2022-02-23
MX2015012783A (es) 2016-04-28
US20170224785A1 (en) 2017-08-10
US20140271611A1 (en) 2014-09-18
JP2019142850A (ja) 2019-08-29
KR102365936B1 (ko) 2022-02-23
SG10202001227QA (en) 2020-03-30
SG10201707074TA (en) 2017-10-30
KR20210021107A (ko) 2021-02-24
NZ751610A (en) 2020-11-27
US11185575B2 (en) 2021-11-30
IL241305A0 (en) 2015-11-30
KR102513872B1 (ko) 2023-03-27
WO2014151968A8 (en) 2015-10-15
AU2018203665A1 (en) 2018-06-14
US20220080032A1 (en) 2022-03-17
PL2968483T3 (pl) 2022-04-04
EP3960196A1 (en) 2022-03-02
KR20200041394A (ko) 2020-04-21
EP2968483B1 (en) 2021-12-01
AU2013203062B2 (en) 2016-06-23
US10413600B2 (en) 2019-09-17
JP7238088B2 (ja) 2023-03-13
AU2013203062A1 (en) 2014-10-02
IL290486B1 (en) 2023-04-01
JP2022027991A (ja) 2022-02-14

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