PL2877479T3 - Sposób oczyszczania saponin - Google Patents

Sposób oczyszczania saponin

Info

Publication number
PL2877479T3
PL2877479T3 PL13742207T PL13742207T PL2877479T3 PL 2877479 T3 PL2877479 T3 PL 2877479T3 PL 13742207 T PL13742207 T PL 13742207T PL 13742207 T PL13742207 T PL 13742207T PL 2877479 T3 PL2877479 T3 PL 2877479T3
Authority
PL
Poland
Prior art keywords
saponins
purification
Prior art date
Application number
PL13742207T
Other languages
English (en)
Inventor
Juan Jose DIAZ GARCIA
Margit Theresia HOLZER
Original Assignee
Glaxosmithkline Biologicals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals S.A. filed Critical Glaxosmithkline Biologicals S.A.
Publication of PL2877479T3 publication Critical patent/PL2877479T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
    • C07J71/0052—Nitrogen only at position 16(17)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
PL13742207T 2012-07-27 2013-07-25 Sposób oczyszczania saponin PL2877479T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1213364.1A GB201213364D0 (en) 2012-07-27 2012-07-27 Purification process
PCT/EP2013/065708 WO2014016374A1 (en) 2012-07-27 2013-07-25 Process for the purification of saponins
EP13742207.7A EP2877479B1 (en) 2012-07-27 2013-07-25 Process for the purification of saponins

Publications (1)

Publication Number Publication Date
PL2877479T3 true PL2877479T3 (pl) 2019-06-28

Family

ID=46881236

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13742207T PL2877479T3 (pl) 2012-07-27 2013-07-25 Sposób oczyszczania saponin

Country Status (18)

Country Link
US (1) US9540416B2 (pl)
EP (1) EP2877479B1 (pl)
JP (1) JP6360830B2 (pl)
CN (1) CN104662031B (pl)
BR (1) BR112015001655B1 (pl)
CA (1) CA2879709C (pl)
CY (1) CY1121304T1 (pl)
DK (1) DK2877479T3 (pl)
ES (1) ES2708783T3 (pl)
GB (1) GB201213364D0 (pl)
HR (1) HRP20190123T1 (pl)
HU (1) HUE042179T2 (pl)
LT (1) LT2877479T (pl)
PL (1) PL2877479T3 (pl)
PT (1) PT2877479T (pl)
SI (1) SI2877479T1 (pl)
TR (1) TR201901100T4 (pl)
WO (1) WO2014016374A1 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3769618A1 (en) * 2014-06-09 2021-01-27 Terumo BCT, Inc. Lyophilization container
WO2017088080A1 (es) 2015-11-25 2017-06-01 Natural Response S.A. Método para la obtención de saponinas a partir de plantas
MX2019003480A (es) 2016-09-26 2019-09-19 Natural Response S A Produccion de biomasa en plantaciones de ultra alta densidad.
BR112020010635A2 (pt) 2017-12-01 2020-11-10 Glaxosmithkline Biologicals S.A. extração de saponina
WO2019106192A1 (en) 2017-12-01 2019-06-06 Glaxosmithkline Biologicals Sa Saponin purification
JP7640473B2 (ja) 2019-06-05 2025-03-05 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム サポニン精製
CN110404113A (zh) * 2019-08-29 2019-11-05 上海白衣缘生物工程有限公司 一种制备无细胞医用植入材料的方法
AU2021321944A1 (en) 2020-08-07 2023-04-06 Access To Advanced Health Institute Purified saponins and chromatographic process for purification of same
MX2023006769A (es) 2020-12-09 2023-08-18 Glaxosmithkline Biologicals Sa Modificacion de saponinas.
WO2023242187A1 (en) 2022-06-15 2023-12-21 Glaxosmithkline Biologicals Sa Enzymatic modification of saponins

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
GB9106048D0 (en) 1991-03-21 1991-05-08 Smithkline Beecham Biolog Vaccines
UA56132C2 (uk) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
US6231859B1 (en) * 1996-12-02 2001-05-15 Aquila Biopharmaceuticals, Inc. Saponin adjuvant compositions
CA2273922C (en) * 1996-12-02 2008-08-05 Antigenics Inc. Novel saponin compositions and uses thereof
WO1998056415A1 (en) * 1997-06-11 1998-12-17 Aquila Biopharmaceuticals, Inc. Purified saponins as oral adjuvants
US6231858B1 (en) 1998-01-09 2001-05-15 Mochida Corporation Bolus for radiotherapy
EP1071441A1 (en) 1998-04-17 2001-01-31 Her Majesty The Queen in Right of Canada, as represented by The Minister of Agriculture and Agri-Food Canada Process for recovery and purification of saponins and sapogenins from quinoa (chenopodium quinoa)
GB2373743B (en) * 2001-03-27 2004-11-03 Membrane Extraction Tech Ltd Solvent exchange process
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
GB0525321D0 (en) * 2005-12-13 2006-01-18 Glaxosmithkline Biolog Sa Novel compositions
CN102462718A (zh) 2010-11-19 2012-05-23 苏州宝泽堂医药科技有限公司 一种青阳参皂苷的提取方法
CN102232977A (zh) 2011-05-06 2011-11-09 南京泽朗医药科技有限公司 一种从商陆中提取总皂苷的方法
CN102351938B (zh) 2011-09-01 2012-09-26 安徽农业大学 一种高纯度茶皂素的制备方法

Also Published As

Publication number Publication date
HUE042179T2 (hu) 2019-06-28
JP6360830B2 (ja) 2018-07-18
DK2877479T3 (en) 2019-02-25
US20140030318A1 (en) 2014-01-30
ES2708783T3 (es) 2019-04-11
TR201901100T4 (tr) 2019-02-21
WO2014016374A1 (en) 2014-01-30
CA2879709A1 (en) 2014-01-30
US9540416B2 (en) 2017-01-10
SI2877479T1 (sl) 2019-03-29
BR112015001655A2 (pt) 2017-07-04
JP2015522643A (ja) 2015-08-06
GB201213364D0 (en) 2012-09-12
CA2879709C (en) 2020-10-06
CY1121304T1 (el) 2020-05-29
EP2877479A1 (en) 2015-06-03
CN104662031B (zh) 2017-11-03
LT2877479T (lt) 2019-01-10
PT2877479T (pt) 2019-01-28
HRP20190123T1 (hr) 2019-03-08
CN104662031A (zh) 2015-05-27
EP2877479B1 (en) 2018-11-14
BR112015001655B1 (pt) 2021-08-17

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