PL2854870T3 - Sposób i urządzenie do wytwarzania ołowiu 212 do zastosowania medycznego - Google Patents

Sposób i urządzenie do wytwarzania ołowiu 212 do zastosowania medycznego

Info

Publication number
PL2854870T3
PL2854870T3 PL13725620T PL13725620T PL2854870T3 PL 2854870 T3 PL2854870 T3 PL 2854870T3 PL 13725620 T PL13725620 T PL 13725620T PL 13725620 T PL13725620 T PL 13725620T PL 2854870 T3 PL2854870 T3 PL 2854870T3
Authority
PL
Poland
Prior art keywords
lead
production
medical use
medical
Prior art date
Application number
PL13725620T
Other languages
English (en)
Inventor
Julien Torgue
Patrick Maquaire
John Young
Gilbert Andreoletti
Patrick Bourdet
Original Assignee
Orano Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orano Med filed Critical Orano Med
Publication of PL2854870T3 publication Critical patent/PL2854870T3/pl

Links

Classifications

    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21GCONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/0005Isotope delivery systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/12Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the preparation of the feed
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/42Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424Elution mode
    • CCHEMISTRY; METALLURGY
    • C22METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22BPRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
    • C22B13/00Obtaining lead
    • C22B13/02Obtaining lead by dry processes
    • CCHEMISTRY; METALLURGY
    • C22METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22BPRODUCTION AND REFINING OF METALS; PRETREATMENT OF RAW MATERIALS
    • C22B13/00Obtaining lead
    • C22B13/06Refining
    • CCHEMISTRY; METALLURGY
    • C22METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22CALLOYS
    • C22C11/00Alloys based on lead
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/06Preparation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/84Preparation of the fraction to be distributed
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/06Preparation
    • G01N2030/067Preparation by reaction, e.g. derivatising the sample
    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21GCONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/001Recovery of specific isotopes from irradiated targets
    • G21G2001/0094Other isotopes not provided for in the groups listed above
    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21GCONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G4/00Radioactive sources
    • G21G4/04Radioactive sources other than neutron sources
    • G21G4/06Radioactive sources other than neutron sources characterised by constructional features
    • G21G4/08Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
PL13725620T 2012-05-24 2013-05-23 Sposób i urządzenie do wytwarzania ołowiu 212 do zastosowania medycznego PL2854870T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1254798A FR2990956B1 (fr) 2012-05-24 2012-05-24 Procede et appareil pour la production de plomb 212 a usage medical
PCT/EP2013/060672 WO2013174949A1 (en) 2012-05-24 2013-05-23 Method and apparatus for the production of lead 212 for medical use
EP13725620.2A EP2854870B1 (en) 2012-05-24 2013-05-23 Method and apparatus for the production of lead 212 for medical use

Publications (1)

Publication Number Publication Date
PL2854870T3 true PL2854870T3 (pl) 2019-01-31

Family

ID=48536828

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13725620T PL2854870T3 (pl) 2012-05-24 2013-05-23 Sposób i urządzenie do wytwarzania ołowiu 212 do zastosowania medycznego

Country Status (12)

Country Link
US (2) US10020086B2 (pl)
EP (1) EP2854870B1 (pl)
JP (1) JP6392210B2 (pl)
AU (1) AU2013265268B2 (pl)
DK (1) DK2854870T3 (pl)
ES (1) ES2683398T3 (pl)
FR (1) FR2990956B1 (pl)
PL (1) PL2854870T3 (pl)
PT (1) PT2854870T (pl)
SI (1) SI2854870T1 (pl)
TR (1) TR201811310T4 (pl)
WO (1) WO2013174949A1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015160981A1 (en) 2014-04-15 2015-10-22 Lantheus Medical Imaging, Inc. Methods and devices for isolating lead 203
CN104528652B (zh) * 2015-01-26 2016-04-06 中国工程物理研究院核物理与化学研究所 直立式Na131I干馏生产装置
CN104528653B (zh) * 2015-01-26 2017-01-11 中国工程物理研究院核物理与化学研究所 一种立式Na131I干馏生产装置
CA3187489A1 (en) * 2015-02-09 2016-08-18 Framatome Gmbh Radionuclide generation system
US9433690B1 (en) * 2015-02-26 2016-09-06 Sciencons AS Radiopharmaceutical solutions with advantageous properties
EP3174068B1 (en) 2015-11-30 2018-06-20 Orano Med New method and apparatus for the production of high purity radionuclides
FR3086186B1 (fr) * 2018-09-26 2022-01-28 Orano Med Procede de production de plomb-212 a partir d'une solution aqueuse comprenant du thorium-228 et ses descendants
EP3800648A1 (en) * 2019-10-04 2021-04-07 Sck Cen Methods and systems for the production of isotopes
US20230014219A1 (en) * 2019-12-05 2023-01-19 Sciencons AS Production of highly purified 212pb
IL310474A (en) 2021-08-11 2024-03-01 Nuclear Res And Consultancy Group System and method of production and isolation of charged radionuclides
WO2023023731A1 (en) * 2021-08-23 2023-03-02 AdvanCell Isotopes Pty Limited Materials and processes for generating radioisotope
US11383204B1 (en) 2021-09-08 2022-07-12 Potentgen Nükleer Tip Biyoteknoloji Klinik Araştirma Ve Danişmanlik Anonim Şirket Method for production of lead-212 isotope

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663129A (en) * 1985-01-30 1987-05-05 The United States Of America As Represented By The United States Department Of Energy Isotopic generator for bismuth-212 and lead-212 from radium
US5038046A (en) * 1990-07-10 1991-08-06 Biotechnetics Method and generator for producing radioactive lead-212
CA2261772C (en) * 1996-08-26 2003-12-09 Paul V. Harper Process and apparatus for the production of bi-212 and a use thereof
JP4495453B2 (ja) * 2001-06-22 2010-07-07 ピージー リサーチ ファンデーション,インコーポレーテッド 自動放射性核種分離システム
CA2451154C (en) * 2001-06-22 2012-02-07 Pg Research Foundation, Inc. Compact automated radionuclide separator
US6998052B2 (en) * 2002-04-12 2006-02-14 Pg Research Foundation Multicolumn selectivity inversion generator for production of ultrapure radionuclides
US9283521B2 (en) * 2002-06-14 2016-03-15 Parker-Hannifin Corporation Single-use manifold and sensors for automated, aseptic transfer of solutions in bioprocessing applications
AU2005215234B2 (en) * 2004-02-20 2009-02-19 Algeta As Alpha-emitting Hydroxyapatite particles
GB2436508C (en) * 2005-01-14 2011-01-26 Europ Organisation For Nuclear Res Cern Method for production of radioisotope preparationsand their use in life science, research, medical application and industry.
US20070009409A1 (en) * 2005-07-11 2007-01-11 Hariprasad Gali 212Bi or 213Bi Generator from supported parent isotope
EP1949387B1 (en) * 2005-10-03 2015-11-11 Mallinckrodt LLC Radiopharmaceutical system and method utilizing radio-frequency identification tags
US7700926B2 (en) * 2006-01-12 2010-04-20 Draximage General Partnership Systems and methods for radioisotope generation
US7586102B2 (en) * 2006-08-14 2009-09-08 Board Of Regents The University Of Texas System Automated system for formulating radiopharmaceuticals
US9326742B2 (en) * 2007-01-01 2016-05-03 Bayer Healthcare Llc Systems for integrated radiopharmaceutical generation, preparation, transportation and administration
AU2008243144A1 (en) * 2008-11-06 2010-05-20 Quark Technologies Australia Pty Ltd Improvements in Radiopharmaceutical Purification
US8273300B2 (en) * 2009-07-09 2012-09-25 Siemens Medical Solutions Usa, Inc. Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure
US8435454B2 (en) * 2009-07-09 2013-05-07 Siemens Medical Solutions Usa, Inc. Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure
US20120108858A1 (en) * 2010-10-28 2012-05-03 Maxim Kiselev Method and device for manufacturing of radiopharmaceuticals
CA2854820C (en) * 2011-12-08 2016-05-24 Nordion (Canada) Inc. Method of pre-treating an adsorbent for a chromatographic separation
EP3062826B1 (en) * 2013-10-30 2018-09-19 Northstar Medical Radioisotopes LLC System for processing and tracking radionuclides

Also Published As

Publication number Publication date
US10020086B2 (en) 2018-07-10
EP2854870A1 (en) 2015-04-08
AU2013265268B2 (en) 2016-07-07
JP6392210B2 (ja) 2018-09-19
JP2015523555A (ja) 2015-08-13
AU2013265268A1 (en) 2014-12-18
ES2683398T3 (es) 2018-09-26
US20150170776A1 (en) 2015-06-18
AU2013265268A2 (en) 2016-06-30
DK2854870T3 (en) 2018-08-06
US20180308600A1 (en) 2018-10-25
SI2854870T1 (sl) 2018-10-30
EP2854870B1 (en) 2018-05-16
TR201811310T4 (tr) 2018-08-27
WO2013174949A1 (en) 2013-11-28
FR2990956B1 (fr) 2014-07-04
US11037690B2 (en) 2021-06-15
PT2854870T (pt) 2018-10-03
FR2990956A1 (fr) 2013-11-29

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