PL2812328T3 - Modulatory kinaz Aurora i FLT3 - Google Patents
Modulatory kinaz Aurora i FLT3Info
- Publication number
- PL2812328T3 PL2812328T3 PL13702642T PL13702642T PL2812328T3 PL 2812328 T3 PL2812328 T3 PL 2812328T3 PL 13702642 T PL13702642 T PL 13702642T PL 13702642 T PL13702642 T PL 13702642T PL 2812328 T3 PL2812328 T3 PL 2812328T3
- Authority
- PL
- Poland
- Prior art keywords
- aurora
- flt3 kinases
- modulators
- kinases modulators
- flt3
- Prior art date
Links
- 101100335081 Mus musculus Flt3 gene Proteins 0.000 title 1
- 239000005441 aurora Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1202027.7A GB201202027D0 (en) | 2012-02-06 | 2012-02-06 | Pharmaceutical compounds |
| EP13702642.3A EP2812328B1 (en) | 2012-02-06 | 2013-02-04 | Aurora and flt3 kinases modulators |
| PCT/EP2013/052182 WO2013117522A1 (en) | 2012-02-06 | 2013-02-04 | Aurora and flt3 kinases modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2812328T3 true PL2812328T3 (pl) | 2016-04-29 |
Family
ID=45896692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13702642T PL2812328T3 (pl) | 2012-02-06 | 2013-02-04 | Modulatory kinaz Aurora i FLT3 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9133180B2 (enExample) |
| EP (1) | EP2812328B1 (enExample) |
| JP (1) | JP6034880B2 (enExample) |
| KR (1) | KR102052780B1 (enExample) |
| CN (1) | CN104169277B (enExample) |
| AU (1) | AU2013218167B2 (enExample) |
| BR (1) | BR112014019254B1 (enExample) |
| CA (1) | CA2863759C (enExample) |
| DK (1) | DK2812328T3 (enExample) |
| ES (1) | ES2560260T3 (enExample) |
| GB (1) | GB201202027D0 (enExample) |
| IL (1) | IL233988A (enExample) |
| MX (1) | MX338481B (enExample) |
| PL (1) | PL2812328T3 (enExample) |
| PT (1) | PT2812328E (enExample) |
| RU (1) | RU2643809C2 (enExample) |
| SG (1) | SG11201404277WA (enExample) |
| WO (1) | WO2013117522A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2522968B2 (ja) | 1987-10-23 | 1996-08-07 | 尾池工業株式会社 | 印刷回路転写箔およびその製造法 |
| JP7365332B2 (ja) * | 2017-08-07 | 2023-10-19 | ジョイント・ストック・カンパニー “バイオキャド” | Ｃｄｋ８／１９阻害薬としての新規ヘテロ環式化合物 |
| GB201816369D0 (en) | 2018-10-08 | 2018-11-28 | Sareum Ltd | Pharmaceutical compounds |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE794096A (fr) | 1972-08-07 | 1973-05-16 | Lepetit Spa | Oxazoles 2,4,5-trisubstitues et leur preparation |
| US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
| US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5192659A (en) | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
| JPH06310767A (ja) | 1993-04-26 | 1994-11-04 | Nec Corp | 寒剤容器の断熱支持構造 |
| US6218529B1 (en) | 1995-07-31 | 2001-04-17 | Urocor, Inc. | Biomarkers and targets for diagnosis, prognosis and management of prostate, breast and bladder cancer |
| WO1998004689A1 (en) | 1995-07-31 | 1998-02-05 | Urocor, Inc. | Biomarkers and targets for diagnosis, prognosis and management of prostate disease |
| DE19653355A1 (de) | 1996-12-20 | 1998-06-25 | Dresden Arzneimittel | Neue, antikonvulsiv wirkende Aminoimidazole und Verfahren zu ihrer Herstellung |
| GB0003154D0 (en) | 2000-02-12 | 2000-04-05 | Astrazeneca Uk Ltd | Novel compounds |
| CN1267431C (zh) | 2000-06-28 | 2006-08-02 | 阿斯特拉曾尼卡有限公司 | 取代的喹唑啉衍生物及其在制备作为抑制剂的药物中的用途 |
| PL205536B1 (pl) | 2000-10-30 | 2010-04-30 | Janssen Pharmaceutica Nv | Podstawiona pochodna dihydroindolu, dihydrochinoliny lub dihydroizochinoliny jako inhibitor peptydazy tripeptydowej, jej zastosowanie i sposób wytwarzania oraz kompozycja farmaceutyczna |
| CA2491895C (en) | 2002-07-09 | 2011-01-18 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases |
| AU2003902208A0 (en) * | 2003-05-08 | 2003-05-22 | Fujisawa Pharmaceutical Co., Ltd. | Inhibitor of cox |
| ATE465731T1 (de) | 2003-10-23 | 2010-05-15 | Ab Science | 2-aminoaryloxazol-verbindungen als tyrosinkinase- hemmer |
| BRPI0511139B8 (pt) * | 2004-05-14 | 2021-05-25 | Millennium Pharm Inc | compostos que inibem quinase aurora e composição farmacêutica contendo os mesmos |
| GB0504753D0 (en) | 2005-03-08 | 2005-04-13 | Astrazeneca Ab | Chemical compounds |
| WO2007043401A1 (ja) | 2005-10-07 | 2007-04-19 | Kissei Pharmaceutical Co., Ltd. | 含窒素複素環化合物およびそれを含有する医薬組成物 |
| DK200600313A (da) | 2006-03-03 | 2006-03-13 | Novo Nordisk As | Treating type 2 diabetes or metabolic syndrome with an interleukin 1beta inhibitor or an interleukin 1beta synthesis or release inhibitor |
| DE602007009085D1 (de) | 2006-05-12 | 2010-10-21 | Ab Science | Neues verfahren zur synthese von 2-aminooxazolverbindungen |
| US20090093452A1 (en) | 2006-08-24 | 2009-04-09 | Pfizer Inc. | Pyrrole, Thiophene, Furan, Imidazole, Oxazole, and Thiazole Derivatives |
| JO2701B1 (en) * | 2006-12-21 | 2013-03-03 | جلاكسو جروب ليميتد | Vehicles |
| GB0709031D0 (en) * | 2007-05-10 | 2007-06-20 | Sareum Ltd | Pharmaceutical compounds |
| US8278335B2 (en) | 2008-04-21 | 2012-10-02 | Merck Sharp & Dohme Corp. | Inhibitors of Janus kinases |
| GB0820819D0 (en) | 2008-11-13 | 2008-12-24 | Sareum Ltd | Pharmaceutical compounds |
| EP2320293A1 (en) * | 2009-11-05 | 2011-05-11 | Koninklijke Philips Electronics N.V. | Sleep element for improving the sleep of a person |
| AR079993A1 (es) * | 2010-01-12 | 2012-03-07 | Ab Science | Derivados de azol, composiciones farmaceuticas y sus usos para tratar trastornos mediados por una sobreactividad de quinasas |
| WO2012021611A1 (en) | 2010-08-11 | 2012-02-16 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| US20130231340A1 (en) | 2012-03-02 | 2013-09-05 | Sareum Limited | Pharmaceutical compounds |
-
2012
- 2012-02-06 GB GBGB1202027.7A patent/GB201202027D0/en not_active Ceased
-
2013
- 2013-02-04 JP JP2014555250A patent/JP6034880B2/ja active Active
- 2013-02-04 DK DK13702642.3T patent/DK2812328T3/en active
- 2013-02-04 CA CA2863759A patent/CA2863759C/en active Active
- 2013-02-04 MX MX2014009323A patent/MX338481B/es active IP Right Grant
- 2013-02-04 BR BR112014019254-5A patent/BR112014019254B1/pt not_active IP Right Cessation
- 2013-02-04 US US14/376,729 patent/US9133180B2/en active Active
- 2013-02-04 WO PCT/EP2013/052182 patent/WO2013117522A1/en not_active Ceased
- 2013-02-04 PL PL13702642T patent/PL2812328T3/pl unknown
- 2013-02-04 PT PT137026423T patent/PT2812328E/pt unknown
- 2013-02-04 EP EP13702642.3A patent/EP2812328B1/en active Active
- 2013-02-04 KR KR1020147024086A patent/KR102052780B1/ko active Active
- 2013-02-04 RU RU2014131784A patent/RU2643809C2/ru active
- 2013-02-04 AU AU2013218167A patent/AU2013218167B2/en not_active Ceased
- 2013-02-04 ES ES13702642.3T patent/ES2560260T3/es active Active
- 2013-02-04 SG SG11201404277WA patent/SG11201404277WA/en unknown
- 2013-02-04 CN CN201380013544.5A patent/CN104169277B/zh active Active
-
2014
- 2014-08-05 IL IL233988A patent/IL233988A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| DK2812328T3 (en) | 2016-01-11 |
| KR20140128373A (ko) | 2014-11-05 |
| RU2014131784A (ru) | 2016-03-27 |
| HK1204327A1 (en) | 2015-11-13 |
| BR112014019254B1 (pt) | 2020-03-10 |
| CA2863759A1 (en) | 2013-08-15 |
| AU2013218167B2 (en) | 2017-04-06 |
| KR102052780B1 (ko) | 2019-12-05 |
| EP2812328B1 (en) | 2015-11-18 |
| SG11201404277WA (en) | 2014-08-28 |
| CN104169277B (zh) | 2016-10-12 |
| GB201202027D0 (en) | 2012-03-21 |
| RU2643809C2 (ru) | 2018-02-06 |
| CA2863759C (en) | 2020-04-14 |
| EP2812328A1 (en) | 2014-12-17 |
| BR112014019254A2 (enExample) | 2017-06-20 |
| US20150018367A1 (en) | 2015-01-15 |
| MX2014009323A (es) | 2015-04-08 |
| US9133180B2 (en) | 2015-09-15 |
| JP6034880B2 (ja) | 2016-11-30 |
| IL233988A (en) | 2017-06-29 |
| BR112014019254A8 (pt) | 2017-07-11 |
| CN104169277A (zh) | 2014-11-26 |
| ES2560260T3 (es) | 2016-02-18 |
| MX338481B (es) | 2016-04-19 |
| JP2015511228A (ja) | 2015-04-16 |
| WO2013117522A1 (en) | 2013-08-15 |
| AU2013218167A1 (en) | 2014-08-14 |
| PT2812328E (pt) | 2016-03-01 |
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