PL2547699T3 - Sposób otrzymywania biologicznie czynnego rekombinowanego ludzkiego g-csf - Google Patents

Sposób otrzymywania biologicznie czynnego rekombinowanego ludzkiego g-csf

Info

Publication number
PL2547699T3
PL2547699T3 PL11709881T PL11709881T PL2547699T3 PL 2547699 T3 PL2547699 T3 PL 2547699T3 PL 11709881 T PL11709881 T PL 11709881T PL 11709881 T PL11709881 T PL 11709881T PL 2547699 T3 PL2547699 T3 PL 2547699T3
Authority
PL
Poland
Prior art keywords
csf
biologically active
recombinant human
active recombinant
obtaining biologically
Prior art date
Application number
PL11709881T
Other languages
English (en)
Inventor
Walter Hinderer
Christian Scheckermann
Original Assignee
Ratiopharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ratiopharm Gmbh filed Critical Ratiopharm Gmbh
Publication of PL2547699T3 publication Critical patent/PL2547699T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL11709881T 2010-03-17 2011-03-17 Sposób otrzymywania biologicznie czynnego rekombinowanego ludzkiego g-csf PL2547699T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10002811 2010-03-17
EP11709881.4A EP2547699B1 (en) 2010-03-17 2011-03-17 Method for obtaining biologically active recombinant human g-csf

Publications (1)

Publication Number Publication Date
PL2547699T3 true PL2547699T3 (pl) 2017-04-28

Family

ID=42153771

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11709881T PL2547699T3 (pl) 2010-03-17 2011-03-17 Sposób otrzymywania biologicznie czynnego rekombinowanego ludzkiego g-csf

Country Status (16)

Country Link
US (1) US8703123B2 (pl)
EP (1) EP2547699B1 (pl)
JP (1) JP5964757B2 (pl)
KR (1) KR101853146B1 (pl)
CN (1) CN102892780B (pl)
AU (1) AU2011229491B2 (pl)
BR (1) BR112012022518A2 (pl)
CA (1) CA2789615A1 (pl)
EA (1) EA022821B1 (pl)
ES (1) ES2611453T3 (pl)
IL (1) IL221808B (pl)
MX (1) MX2012010661A (pl)
NZ (1) NZ601759A (pl)
PL (1) PL2547699T3 (pl)
WO (1) WO2011113601A1 (pl)
ZA (1) ZA201206208B (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011108482A1 (ja) * 2010-03-05 2011-09-09 Dic株式会社 賦型シート及びその製造方法
HUP1200172A2 (en) * 2012-03-19 2013-10-28 Richter Gedeon Nyrt Methods for refolding g-csf from inclusion bodies
CN103908427B (zh) * 2013-01-05 2014-12-17 石药集团百克(山东)生物制药有限公司 一种聚乙二醇修饰的rhG-CSF注射液及其制备方法
WO2014155349A2 (en) * 2013-03-29 2014-10-02 Dr. Reddy's Laboratories Refolding of proteins
WO2014155365A2 (en) * 2013-03-29 2014-10-02 Dr.Reddy's Laboratories Limited Purification method
CN103694339B (zh) * 2013-12-04 2017-10-13 珠海联邦制药股份有限公司 一种甘精胰岛素前体的复性方法
US10457716B2 (en) 2014-08-06 2019-10-29 University Of Notre Dame Du Lac Protein folding and methods of using same
FI3237433T3 (fi) 2014-12-22 2025-10-14 UCB Biopharma SRL Menetelmä proteiinin valmistamiseksi
JP2016183118A (ja) * 2015-03-25 2016-10-20 東ソー株式会社 増殖因子前駆体のリフォールディング方法
GB201506870D0 (en) * 2015-04-22 2015-06-03 Ucb Biopharma Sprl Method
WO2018132787A1 (en) 2017-01-16 2018-07-19 Nansha Biologics (Hk) Limited Systems and methods for production of recombinant il-11 in yeast
US20220195002A1 (en) * 2019-04-24 2022-06-23 Tanvex Biopharma Usa, Inc. Process for preparing granulocyte-colony stimulating factor
KR102375269B1 (ko) * 2021-01-27 2022-03-17 한미약품 주식회사 단백질 액상 제제 및 이의 제조방법
CN118063587A (zh) * 2024-04-17 2024-05-24 山东泉港药业有限公司 一种降低重组人粒细胞刺激因子原液相关蛋白含量的工艺方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79124B (pl) 1982-12-22 1984-10-02 Genentech Inc
ATE107356T1 (de) 1983-03-25 1994-07-15 Celltech Ltd Verfahren zur herstellung eines proteins.
US4530787A (en) 1984-03-28 1985-07-23 Cetus Corporation Controlled oxidation of microbially produced cysteine-containing proteins
DE3537708A1 (de) 1985-10-23 1987-04-23 Boehringer Mannheim Gmbh Verfahren zur aktivierung von t-pa nach expression in prokaryonten
DE3611817A1 (de) 1986-04-08 1987-10-15 Boehringer Mannheim Gmbh Verfahren zur renaturierung von proteinen
FI900178A0 (fi) 1988-05-13 1990-01-12 Amgen Inc Kompositioner och foerfarande foer behandling eller foerhindrande av infektioner hos djur.
DE3835350A1 (de) 1988-10-17 1990-04-19 Boehringer Mannheim Gmbh Aktivierung von gentechnologisch hergestellten, in prokaryonten exprimierten antikoerpern
JPH02234679A (ja) * 1989-03-07 1990-09-17 Sagami Chem Res Center ヒトラミニンｂ１鎖ポリペプチド断片及びこれを生産するための発現ベクター
FR2669646A1 (fr) 1990-11-23 1992-05-29 Lorraine Laminage Procede de traitement d'un effluent aqueux issu d'un procede d'electrozingage, ainsi que procede et installation en comportant application.
DE4105480A1 (de) 1991-02-21 1992-08-27 Boehringer Mannheim Gmbh Verbesserte aktivierung von rekombinanten proteinen
IL152804A0 (en) 2000-05-16 2003-06-24 Bolder Biotechnology Inc Methods for refolding proteins containing free cysteine residues
DE102004041639A1 (de) * 2004-08-27 2006-03-02 Bioceuticals Arzneimittel Ag Verfahren zur Gewinnung von biologisch aktivem humanen G-CSF aus Inclusion Bodies
DE102005033250A1 (de) * 2005-07-15 2007-01-18 Bioceuticals Arzneimittel Ag Verfahren zur Reinigung von G-CSF
GB0605684D0 (en) * 2006-03-21 2006-05-03 Sicor Biotech Uab Method For Purifying Granulocyte-Colony Stimulating Factor
WO2008096370A2 (en) 2007-02-05 2008-08-14 Natco Pharma Limited An efficient and novel purification method of recombinant hg-csf
CN101796063B (zh) 2007-04-03 2017-03-22 拉蒂奥法姆有限责任公司 使用糖聚乙二醇化g‑csf的治疗方法
DK2197919T3 (da) 2007-08-27 2014-07-07 Ratiopharm Gmbh Flydende formulering af g-csf-konjugat
WO2010024271A1 (ja) * 2008-08-27 2010-03-04 三菱化学メディエンス株式会社 修飾抗ヘパリン／pf4複合体抗体及びhit抗体標準品

Also Published As

Publication number Publication date
US20120328560A1 (en) 2012-12-27
ZA201206208B (en) 2013-05-29
US8703123B2 (en) 2014-04-22
ES2611453T3 (es) 2017-05-09
AU2011229491B2 (en) 2015-02-05
EP2547699B1 (en) 2016-10-19
NZ601759A (en) 2013-07-26
AU2011229491A1 (en) 2012-09-06
EA201290684A1 (ru) 2013-03-29
CN102892780A (zh) 2013-01-23
EP2547699A1 (en) 2013-01-23
WO2011113601A1 (en) 2011-09-22
KR101853146B1 (ko) 2018-04-27
KR20130054948A (ko) 2013-05-27
IL221808B (en) 2018-06-28
JP5964757B2 (ja) 2016-08-03
CA2789615A1 (en) 2011-09-22
EA022821B1 (ru) 2016-03-31
BR112012022518A2 (pt) 2020-10-13
JP2013522252A (ja) 2013-06-13
MX2012010661A (es) 2013-03-25
CN102892780B (zh) 2015-07-29

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