PL2448600T3 - Związki ukierunkowane na kationoniezależny receptor mannozo-6-fosforanu - Google Patents
Związki ukierunkowane na kationoniezależny receptor mannozo-6-fosforanuInfo
- Publication number
- PL2448600T3 PL2448600T3 PL10727003.5T PL10727003T PL2448600T3 PL 2448600 T3 PL2448600 T3 PL 2448600T3 PL 10727003 T PL10727003 T PL 10727003T PL 2448600 T3 PL2448600 T3 PL 2448600T3
- Authority
- PL
- Poland
- Prior art keywords
- cation
- compounds targeting
- phosphate receptor
- independent mannose
- mannose
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09305647 | 2009-07-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2448600T3 true PL2448600T3 (pl) | 2016-10-31 |
Family
ID=41279432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10727003.5T PL2448600T3 (pl) | 2009-07-03 | 2010-07-02 | Związki ukierunkowane na kationoniezależny receptor mannozo-6-fosforanu |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8962573B2 (pl) |
| EP (1) | EP2448600B1 (pl) |
| JP (1) | JP5837486B2 (pl) |
| CA (1) | CA2766614C (pl) |
| ES (1) | ES2576853T3 (pl) |
| PL (1) | PL2448600T3 (pl) |
| WO (1) | WO2011000958A1 (pl) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3205351B1 (en) | 2010-04-23 | 2023-04-12 | Alexion Pharmaceuticals, Inc. | Lysosomal storage disease enzyme |
| MX365007B (es) | 2010-09-09 | 2019-05-20 | Alexion Pharmaceuticals Inc Star | Uso de acido lipasa lisosomal para tratar la dificiencia de acido lipasa lisosomal en pacientes. |
| US9138465B2 (en) | 2011-04-28 | 2015-09-22 | Osaka University | Pharmaceutical composition for treating lysosomal storage disease |
| WO2013055888A2 (en) * | 2011-10-12 | 2013-04-18 | Synageva Biopharma Corp. | Recombinant human naglu protein and uses thereof |
| CA2881420C (en) | 2012-08-16 | 2016-11-15 | Pfizer Inc. | Glycoconjugation processes and compositions |
| CN102993256B (zh) * | 2012-12-31 | 2016-05-18 | 浙江大学 | 一种选择性脱除全三甲基硅基保护糖的伯位三甲基硅基的方法 |
| AU2014235004B2 (en) * | 2013-03-15 | 2018-08-16 | Newlink Genetics Corporation | Carbohydrate-modified glycoproteins and uses thereof |
| FR3041345B1 (fr) * | 2015-09-18 | 2019-06-14 | Nanomedsyn | Composes polysaccharides multi-fonctionnalises et leur utilisation pour cibler le recepteur du mannose 6-phosphate cation-independant |
| MX2018005258A (es) | 2015-11-06 | 2019-09-04 | Biomarin Pharm Inc | Ensayos basados en células para la detección de anticuerpos u otros factores que neutralizan la absorción de enzimas lisosómicas. |
| JP7466927B2 (ja) * | 2018-08-10 | 2024-04-15 | ニューヨーク ユニバーシティ | アンジェルマン症候群及び自閉症を治療するためのｉｇｆ―２受容体作動剤リガンドの使用 |
| EP3833380A4 (en) * | 2018-08-10 | 2022-04-13 | New York University | USE OF MANNOSE-6-PHOSPHATE AND ITS MODIFICATIONS FOR MEMORY IMPROVEMENT AND REDUCTION OF MEMORY DISORDERS |
| US20220023434A1 (en) | 2018-12-19 | 2022-01-27 | The Board Of Trustees Of The Leland Stanford Junior University | Bifunctional Molecules for Lysosomal Targeting and Related Compositions and Methods |
| CN110893236A (zh) * | 2019-10-09 | 2020-03-20 | 中山大学 | 溶酶体靶向的抗体药物偶联物及其应用 |
| FR3132634A1 (fr) | 2022-02-15 | 2023-08-18 | Nanomedsyn | Composés bifonctionnels ciblant le récepteur du mannose 6-phosphate cation-indépendant |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE308344T1 (de) | 1998-10-08 | 2005-11-15 | Stichting Tech Wetenschapp | Auf peptiden basierende tragvorrichtungen für sternzellen |
| US7001994B2 (en) | 2001-01-18 | 2006-02-21 | Genzyme Corporation | Methods for introducing mannose 6-phosphate and other oligosaccharides onto glycoproteins |
| EP1616034A4 (en) | 2003-04-01 | 2008-12-03 | Activx Biosciences Inc | ACYL PHOSPHATE AND PHOSPHONATE EASTS AND PROCESSES FOR THEIR SYNTHESIS AND USE IN PROTEAM ANALYSIS |
| ATE387217T1 (de) * | 2003-07-11 | 2008-03-15 | Lbr Medbiotech B V | Mannose-6-phosphat rezeptor vermittelter gentransfer zu muskelzellen |
| GB0326546D0 (en) | 2003-11-14 | 2003-12-17 | Amersham Plc | Inhibitor imaging agents |
| CA2571431A1 (en) * | 2004-06-24 | 2006-01-05 | The Scripps Research Institute | Arrays with cleavable linkers |
| HUE036140T2 (hu) | 2007-01-18 | 2018-06-28 | Genzyme Corp | Aminooxi-csoportot tartalmazó oligoszacharidok és ezek konjugátjai |
| WO2008089339A2 (en) | 2007-01-18 | 2008-07-24 | Genzyme Corporation | Oligosaccharide conjugates for cellular targeting |
| JP5069920B2 (ja) * | 2007-02-08 | 2012-11-07 | 公益財団法人東京都医学総合研究所 | マンノース６−リン酸−ポリエチレングリコール結合体 |
| CN102827166A (zh) | 2007-04-11 | 2012-12-19 | 默克和西伊公司 | 18f-标记的叶酸类 |
| CA2696699A1 (en) | 2007-08-20 | 2009-02-26 | Protalix Ltd. | Saccharide-containing protein conjugates and uses thereof |
-
2010
- 2010-07-02 WO PCT/EP2010/059507 patent/WO2011000958A1/en active Application Filing
- 2010-07-02 ES ES10727003.5T patent/ES2576853T3/es active Active
- 2010-07-02 JP JP2012518097A patent/JP5837486B2/ja active Active
- 2010-07-02 PL PL10727003.5T patent/PL2448600T3/pl unknown
- 2010-07-02 CA CA2766614A patent/CA2766614C/en active Active
- 2010-07-02 US US13/380,199 patent/US8962573B2/en active Active
- 2010-07-02 EP EP10727003.5A patent/EP2448600B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US8962573B2 (en) | 2015-02-24 |
| US20120093795A1 (en) | 2012-04-19 |
| EP2448600A1 (en) | 2012-05-09 |
| WO2011000958A1 (en) | 2011-01-06 |
| CA2766614C (en) | 2018-06-19 |
| JP2012531458A (ja) | 2012-12-10 |
| EP2448600B1 (en) | 2016-03-30 |
| ES2576853T3 (es) | 2016-07-11 |
| CA2766614A1 (en) | 2011-01-06 |
| JP5837486B2 (ja) | 2015-12-24 |
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