PL2442651T3 - Leczenie stwardnienia rozsianego za pomocą lakwinimodu - Google Patents
Leczenie stwardnienia rozsianego za pomocą lakwinimoduInfo
- Publication number
- PL2442651T3 PL2442651T3 PL10789873T PL10789873T PL2442651T3 PL 2442651 T3 PL2442651 T3 PL 2442651T3 PL 10789873 T PL10789873 T PL 10789873T PL 10789873 T PL10789873 T PL 10789873T PL 2442651 T3 PL2442651 T3 PL 2442651T3
- Authority
- PL
- Poland
- Prior art keywords
- laquinimod
- treatment
- multiple sclerosis
- sclerosis
- Prior art date
Links
- GKWPCEFFIHSJOE-UHFFFAOYSA-N laquinimod Chemical compound OC=1C2=C(Cl)C=CC=C2N(C)C(=O)C=1C(=O)N(CC)C1=CC=CC=C1 GKWPCEFFIHSJOE-UHFFFAOYSA-N 0.000 title 1
- 229960004577 laquinimod Drugs 0.000 title 1
- 201000006417 multiple sclerosis Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/215—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26907009P | 2009-06-19 | 2009-06-19 | |
EP10789873.6A EP2442651B1 (en) | 2009-06-19 | 2010-06-18 | Treatment of multiple sclerosis with laquinimod |
PCT/US2010/001759 WO2010147665A1 (en) | 2009-06-19 | 2010-06-18 | Treatment of multiple sclerosis with laquinimod |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2442651T3 true PL2442651T3 (pl) | 2015-12-31 |
Family
ID=43354572
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL10789873T PL2442651T3 (pl) | 2009-06-19 | 2010-06-18 | Leczenie stwardnienia rozsianego za pomocą lakwinimodu |
Country Status (26)
Country | Link |
---|---|
US (7) | US20100322900A1 (pl) |
EP (2) | EP3028572A1 (pl) |
JP (4) | JP2012530701A (pl) |
KR (2) | KR20120037477A (pl) |
CN (2) | CN102802415A (pl) |
AU (2) | AU2010260455A1 (pl) |
BR (1) | BR112012000568A2 (pl) |
CY (1) | CY1116727T1 (pl) |
DK (1) | DK2442651T3 (pl) |
EA (1) | EA201270041A1 (pl) |
ES (1) | ES2548999T3 (pl) |
HK (1) | HK1169563A1 (pl) |
HR (1) | HRP20150988T1 (pl) |
HU (1) | HUE026406T2 (pl) |
IL (2) | IL216780A0 (pl) |
ME (1) | ME02282B (pl) |
MX (1) | MX2011013902A (pl) |
NZ (1) | NZ597378A (pl) |
PL (1) | PL2442651T3 (pl) |
PT (1) | PT2442651E (pl) |
RS (1) | RS54328B1 (pl) |
SG (2) | SG10201403397TA (pl) |
SI (1) | SI2442651T1 (pl) |
SM (1) | SMT201500262B (pl) |
WO (1) | WO2010147665A1 (pl) |
ZA (1) | ZA201200029B (pl) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2843209B2 (ja) * | 1992-07-28 | 1999-01-06 | 株式会社クボタ | 苗詰め装置 |
JP5832716B2 (ja) * | 2005-10-19 | 2015-12-16 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドナトリウムの結晶,及びその製造方法 |
KR20160013273A (ko) | 2006-06-12 | 2016-02-03 | 테바 파마슈티컬 인더스트리즈 리미티드 | 안정한 라퀴니모드 제제 |
PT2682120T (pt) | 2007-12-20 | 2016-11-07 | Teva Pharma | Preparações de laquinimod estáveis |
KR20110048571A (ko) * | 2008-09-03 | 2011-05-11 | 테바 파마슈티컬 인더스트리즈 리미티드 | 면역 기능을 지닌 2―옥소―1,2―다이하이드로―퀴놀린 조절제 |
PL3064206T3 (pl) | 2009-08-10 | 2020-02-28 | Active Biotech Ab | Leczenie choroby Huntingtona z zastosowaniem lakwinimodu |
JP2013521305A (ja) * | 2010-03-03 | 2013-06-10 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドを用いるループス関節炎の治療 |
CA2791691A1 (en) * | 2010-03-03 | 2011-09-09 | Teva Pharmaceutical Industries Ltd. | Treatment of lupus nephritis using laquinimod |
CA2791709A1 (en) * | 2010-03-03 | 2011-09-09 | Teva Pharmaceutical Industries Ltd. | Treatment of rheumatoid arthritis with a combination of laquinimod and methotrexate |
SG186948A1 (en) | 2010-07-09 | 2013-02-28 | Teva Pharma | Deuterated n-ethyl-n-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, salts and uses thereof |
SG10201509831XA (en) * | 2010-12-07 | 2015-12-30 | Teva Pharma | Use of laquinimod for reducing fatigue, improving functional status, and improving quality of life in multiple sclerosis patients |
JP2014521659A (ja) * | 2011-07-28 | 2014-08-28 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドおよびインターフェロンβを組み合わせた多発性硬化症の治療 |
IN2014MN00333A (pl) * | 2011-07-28 | 2015-09-25 | Teva Pharma | |
WO2013055907A1 (en) * | 2011-10-12 | 2013-04-18 | Teva Pharmaceutical Industries Ltd. | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
AR089862A1 (es) | 2012-02-03 | 2014-09-24 | Teva Pharma | USO DE LAQUINIMOD PARA EL TRATAMIENTO DE PACIENTES CON ENFERMEDAD DE CROHN EN QUIENES FRACASO UNA TERAPIA ANTI-FACTOR DE NECROSIS TUMORAL a (ANTI-TNFa) DE PRIMERA LINEA |
WO2013123419A1 (en) | 2012-02-16 | 2013-08-22 | Teva Pharmaceutical Industries Ltd. | N-ethyl-n-phenyl-1,2-dihydro-4,5-di-hydroxy-1-methyl-2-oxo-3-quinoline carboxamide, preparation and uses thereof |
US20130259856A1 (en) | 2012-03-27 | 2013-10-03 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with combination of laquinimod and dimethyl fumarate |
AR090885A1 (es) * | 2012-05-02 | 2014-12-10 | Teva Pharma | Uso de laquinimod en alta dosis para el tratamiento de la esclerosis multiple |
TW201350467A (zh) | 2012-05-08 | 2013-12-16 | Teva Pharma | N-乙基-4-羥基-1-甲基-5-(甲基(2,3,4,5,6-五羥基己基)胺基)-2-側氧-n-苯基-1,2-二氫喹啉-3-甲醯胺 |
TW201400117A (zh) * | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
UY34896A (es) * | 2012-07-12 | 2014-02-28 | Teva Pharma | Tratamiento de la esclerosis múltiple con una combinación de laquinimod y fampridina |
TW201410244A (zh) | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療gaba媒介之疾病之拉喹莫德(laquinimod) |
EP2961406A4 (en) * | 2012-10-12 | 2017-01-04 | Teva Pharmaceutical Industries Ltd. | Laquinimod for reducing thalamic damage in multiple sclerosis |
AU2013341506A1 (en) | 2012-11-07 | 2015-06-04 | Teva Pharmaceutical Industries Ltd. | Amine salts of Laquinimod |
MX2015010296A (es) * | 2013-02-15 | 2016-05-05 | Teva Pharma | Tratamiento de formas progresivas de esclerosis multiple con laquinimod. |
CA2901849A1 (en) | 2013-03-14 | 2014-09-25 | Teva Pharmaceutical Industries Ltd. | Crystals of laquinimod sodium and improved process for the manufacture thereof |
JP2016513665A (ja) | 2013-03-14 | 2016-05-16 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドの経皮製剤 |
US20150094332A1 (en) * | 2013-09-27 | 2015-04-02 | Teva Pharmaceutical Industries, Ltd. | Laquinimod Combination Therapy For Treatment Of Multiple Sclerosis |
SG11201608674UA (en) * | 2014-04-29 | 2016-11-29 | Teva Pharma | Laquinimod for the treatment of relapsing-remitting multiple sclerosis (rrms) patients with a high disability status |
WO2016094516A1 (en) * | 2014-12-10 | 2016-06-16 | Teva Pharmaceutical Industries Ltd. | Treatment of multiple sclerosis with combination of laquinimod and a statin |
WO2017048457A1 (en) * | 2015-09-18 | 2017-03-23 | Teva Pharmaceuticals Industries Ltd. | Combination of laquinimod and pridopidine to treat multiple sclerosis |
WO2017120355A1 (en) * | 2016-01-06 | 2017-07-13 | Teva Pharmaceutical Industries Ltd. | Dihydroquinolines and uses thereof |
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US6696407B1 (en) * | 1997-03-21 | 2004-02-24 | The Regents Of The University Of California | Huntington's disease treatment comprising administering aldose reductase inhibitors to increase striatal CNTF |
US6077851A (en) * | 1998-04-27 | 2000-06-20 | Active Biotech Ab | Quinoline derivatives |
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US6852323B2 (en) * | 2000-07-21 | 2005-02-08 | The Regents Of The University Of California | Methods and compositions for preventing and treating male erectile dysfunction and female sexual arousal disorder |
US6307050B1 (en) * | 2000-08-29 | 2001-10-23 | R. T. Alamo Venture I Llc | Method of synthesizing flosequinan from 4-fluoroanthranilic acid |
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JP5832716B2 (ja) * | 2005-10-19 | 2015-12-16 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドナトリウムの結晶,及びその製造方法 |
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PL2676967T3 (pl) * | 2006-02-28 | 2019-12-31 | Biogen Ma Inc. | Metody leczenia chorób zapalnych i autoimmunologicznych za pomocą natalizumabu |
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US20080118553A1 (en) * | 2006-06-12 | 2008-05-22 | Anton Frenkel | Tannate salt form of polypeptide mixtures, their preparation and use |
KR20160013273A (ko) * | 2006-06-12 | 2016-02-03 | 테바 파마슈티컬 인더스트리즈 리미티드 | 안정한 라퀴니모드 제제 |
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WO2009009529A1 (en) * | 2007-07-11 | 2009-01-15 | Medicinova, Inc. | Treatment of progressive neurodegenerative disease with ibudilast |
PT2682120T (pt) * | 2007-12-20 | 2016-11-07 | Teva Pharma | Preparações de laquinimod estáveis |
KR20110048571A (ko) * | 2008-09-03 | 2011-05-11 | 테바 파마슈티컬 인더스트리즈 리미티드 | 면역 기능을 지닌 2―옥소―1,2―다이하이드로―퀴놀린 조절제 |
JP2013521305A (ja) * | 2010-03-03 | 2013-06-10 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドを用いるループス関節炎の治療 |
CA2791709A1 (en) * | 2010-03-03 | 2011-09-09 | Teva Pharmaceutical Industries Ltd. | Treatment of rheumatoid arthritis with a combination of laquinimod and methotrexate |
CA2791691A1 (en) * | 2010-03-03 | 2011-09-09 | Teva Pharmaceutical Industries Ltd. | Treatment of lupus nephritis using laquinimod |
SG186948A1 (en) * | 2010-07-09 | 2013-02-28 | Teva Pharma | Deuterated n-ethyl-n-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, salts and uses thereof |
US20120010239A1 (en) * | 2010-07-09 | 2012-01-12 | Ulf Tomas Fristedt | 5-chloro-4-hydroxy-1-methyl-2-oxo-n-phenyl-1,2-dihydroquinoline-3-carboxamide, salts and uses thereof |
-
2010
- 2010-06-18 EP EP15178731.4A patent/EP3028572A1/en not_active Withdrawn
- 2010-06-18 KR KR1020127001253A patent/KR20120037477A/ko active Application Filing
- 2010-06-18 MX MX2011013902A patent/MX2011013902A/es active IP Right Grant
- 2010-06-18 CN CN2010800272294A patent/CN102802415A/zh active Pending
- 2010-06-18 NZ NZ597378A patent/NZ597378A/en not_active IP Right Cessation
- 2010-06-18 KR KR1020177026329A patent/KR20170109091A/ko not_active Application Discontinuation
- 2010-06-18 JP JP2012516065A patent/JP2012530701A/ja not_active Withdrawn
- 2010-06-18 RS RS20150645A patent/RS54328B1/en unknown
- 2010-06-18 US US12/803,121 patent/US20100322900A1/en not_active Abandoned
- 2010-06-18 PT PT107898736T patent/PT2442651E/pt unknown
- 2010-06-18 BR BR112012000568A patent/BR112012000568A2/pt not_active IP Right Cessation
- 2010-06-18 DK DK10789873.6T patent/DK2442651T3/en active
- 2010-06-18 CN CN201710171011.XA patent/CN107308162A/zh active Pending
- 2010-06-18 ES ES10789873.6T patent/ES2548999T3/es active Active
- 2010-06-18 EA EA201270041A patent/EA201270041A1/ru unknown
- 2010-06-18 SG SG10201403397TA patent/SG10201403397TA/en unknown
- 2010-06-18 PL PL10789873T patent/PL2442651T3/pl unknown
- 2010-06-18 EP EP10789873.6A patent/EP2442651B1/en active Active
- 2010-06-18 WO PCT/US2010/001759 patent/WO2010147665A1/en active Application Filing
- 2010-06-18 HU HUE10789873A patent/HUE026406T2/en unknown
- 2010-06-18 SI SI201031018T patent/SI2442651T1/sl unknown
- 2010-06-18 ME MEP-2015-169A patent/ME02282B/me unknown
- 2010-06-18 AU AU2010260455A patent/AU2010260455A1/en not_active Abandoned
- 2010-06-18 SG SG2011092483A patent/SG176840A1/en unknown
-
2011
- 2011-12-06 IL IL216780A patent/IL216780A0/en unknown
-
2012
- 2012-01-03 ZA ZA2012/00029A patent/ZA201200029B/en unknown
- 2012-10-11 HK HK12110013.8A patent/HK1169563A1/xx not_active IP Right Cessation
- 2012-12-12 US US13/712,398 patent/US20130272996A1/en not_active Abandoned
-
2013
- 2013-12-20 US US14/137,778 patent/US20140105850A1/en not_active Abandoned
-
2014
- 2014-12-25 JP JP2014263274A patent/JP2015107981A/ja not_active Withdrawn
-
2015
- 2015-03-02 US US14/635,837 patent/US20150164880A1/en not_active Abandoned
- 2015-09-18 HR HRP20150988TT patent/HRP20150988T1/hr unknown
- 2015-09-30 CY CY20151100869T patent/CY1116727T1/el unknown
- 2015-10-23 SM SM201500262T patent/SMT201500262B/it unknown
- 2015-12-04 US US14/959,845 patent/US20160082001A1/en not_active Abandoned
-
2016
- 2016-06-01 JP JP2016110233A patent/JP2016199555A/ja active Pending
- 2016-08-16 AU AU2016216586A patent/AU2016216586A1/en not_active Abandoned
- 2016-11-28 US US15/362,535 patent/US20170128435A1/en not_active Abandoned
-
2017
- 2017-06-06 IL IL252699A patent/IL252699A0/en unknown
- 2017-08-10 JP JP2017155343A patent/JP2018021045A/ja not_active Withdrawn
- 2017-09-11 US US15/701,157 patent/US20180042916A1/en not_active Abandoned
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