PL2268617T3 - Sposób rozdzielania pochodnych izochinoliny - Google Patents

Sposób rozdzielania pochodnych izochinoliny

Info

Publication number
PL2268617T3
PL2268617T3 PL09714576T PL09714576T PL2268617T3 PL 2268617 T3 PL2268617 T3 PL 2268617T3 PL 09714576 T PL09714576 T PL 09714576T PL 09714576 T PL09714576 T PL 09714576T PL 2268617 T3 PL2268617 T3 PL 2268617T3
Authority
PL
Poland
Prior art keywords
resolution
isoquinoline derivatives
isoquinoline
derivatives
tetrahydropapaverine
Prior art date
Application number
PL09714576T
Other languages
English (en)
Inventor
Franca Segnalini
Angela Tuozzi
Angelo Gentile
Original Assignee
Recordati Ind Chimica E Farmaceutica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Ind Chimica E Farmaceutica Spa filed Critical Recordati Ind Chimica E Farmaceutica Spa
Publication of PL2268617T3 publication Critical patent/PL2268617T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Steroid Compounds (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
PL09714576T 2008-02-28 2009-02-25 Sposób rozdzielania pochodnych izochinoliny PL2268617T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT000319A ITMI20080319A1 (it) 2008-02-28 2008-02-28 Processo per la risoluzione di derivati isochinolinici
PCT/EP2009/052234 WO2009106547A1 (en) 2008-02-28 2009-02-25 Process for the resolution of isoquinoline derivatives
EP09714576A EP2268617B1 (en) 2008-02-28 2009-02-25 Process for the resolution of isoquinoline derivatives

Publications (1)

Publication Number Publication Date
PL2268617T3 true PL2268617T3 (pl) 2012-05-31

Family

ID=40291711

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09714576T PL2268617T3 (pl) 2008-02-28 2009-02-25 Sposób rozdzielania pochodnych izochinoliny

Country Status (13)

Country Link
US (1) US8703955B2 (pl)
EP (1) EP2268617B1 (pl)
CN (1) CN101896462B (pl)
AT (1) ATE534631T1 (pl)
CA (1) CA2708666C (pl)
EA (1) EA017743B1 (pl)
ES (1) ES2375920T3 (pl)
HR (1) HRP20110941T1 (pl)
IL (1) IL206444A (pl)
IT (1) ITMI20080319A1 (pl)
PL (1) PL2268617T3 (pl)
SI (1) SI2268617T1 (pl)
WO (1) WO2009106547A1 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2680277A1 (en) * 2007-03-08 2008-09-12 Chemagis Ltd. (1r,1'r)-atracurium salts separation process
WO2008117271A1 (en) * 2007-03-26 2008-10-02 Chemagis Ltd. (1r,1'r)-atracurium salts separation process
CA2685491A1 (en) 2007-05-01 2008-11-06 Chemagis Ltd. Process for producing cisatracurium compounds and associated intermediates
CA2685488A1 (en) 2007-05-01 2008-11-06 Chemagis Ltd. Novel isoquinolinium compounds useful in the preparation of cisatracurium and associated intermediates
BRPI0811687A2 (pt) 2007-06-18 2015-02-18 Chemagis Ltd MÉTODO PARA SEPARAR O ISÔMETRO 1R-CIS, 1'R-CIS (cisatracúrio) DE UMA MISTURA DE ISÔMEROS DE SAIS DE (1R, 1'R) - ATRACÚRIO
BRPI0816519A2 (pt) 2007-10-29 2015-03-24 Chemagis Ltd Processo para preparar um sal de r, r'-atracúrio isomericamente enriquecido e sal de r, r'-atracúrio
CA2722651A1 (en) * 2008-05-01 2009-11-05 Chemagis Ltd. Cisatracurium derivatives, preparation and uses thereof
US8148527B1 (en) 2011-01-18 2012-04-03 Divi's Laboratories, Ltd. Resolution of 1-(4-methoxybenzyl)-octahydro-isoquinoline
CN103319406A (zh) * 2012-03-20 2013-09-25 迪维斯实验室有限公司 1-(4-甲氧苄基)-八氢-异喹啉的拆分
CN104610145B (zh) * 2015-01-27 2017-07-18 江苏嘉逸医药有限公司 苯磺顺阿曲库铵中间体r‑四氢罂粟碱‑n‑乙酰‑l‑亮氨酸盐的分离方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8418303D0 (en) * 1984-07-18 1984-08-22 Wellcome Found Compounds
DE19535762A1 (de) * 1995-09-26 1997-03-27 Basf Ag Verfahren zur Racematspaltung
DE19711739C1 (de) 1997-03-20 1998-08-20 Knorr Bremse Systeme Governor für Druckluftbeschaffungsanlagen von Fahrzeugen
US6670476B2 (en) 2000-11-29 2003-12-30 Pfizer Inc. Resolution of trans-7-(hydroxy-methyl)octa-hydro-2H-pyrido[1,2-a]pyrazine
EP1831132A2 (en) * 2004-08-02 2007-09-12 Matrix Laboratories Ltd Resolution of racemic organic acids with (1s, 4s)-4[3,4-dichlorophenyl]-1,2,3,4- tetrahydro-n-methyl-1-naphthaloneamine
KR20070080108A (ko) 2006-02-06 2007-08-09 주식회사종근당 질소의 알파 위치에 비대칭탄소가 있는 라세믹 유도체의광학 이성질체 분리 방법

Also Published As

Publication number Publication date
EA201071000A1 (ru) 2011-02-28
SI2268617T1 (sl) 2012-05-31
EA017743B1 (ru) 2013-02-28
ES2375920T3 (es) 2012-03-07
IL206444A (en) 2013-10-31
CN101896462A (zh) 2010-11-24
HRP20110941T1 (hr) 2012-03-31
CN101896462B (zh) 2012-09-26
US20100298570A1 (en) 2010-11-25
CA2708666A1 (en) 2009-09-03
CA2708666C (en) 2016-06-14
HK1150239A1 (en) 2011-11-11
IL206444A0 (en) 2010-12-30
ATE534631T1 (de) 2011-12-15
EP2268617A1 (en) 2011-01-05
EP2268617B1 (en) 2011-11-23
WO2009106547A1 (en) 2009-09-03
US8703955B2 (en) 2014-04-22
ITMI20080319A1 (it) 2009-08-29

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