HRP20110941T1 - Postupak razdvajanja derivata izokinolina - Google Patents

Postupak razdvajanja derivata izokinolina Download PDF

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Publication number
HRP20110941T1
HRP20110941T1 HR20110941T HRP20110941T HRP20110941T1 HR P20110941 T1 HRP20110941 T1 HR P20110941T1 HR 20110941 T HR20110941 T HR 20110941T HR P20110941 T HRP20110941 T HR P20110941T HR P20110941 T1 HRP20110941 T1 HR P20110941T1
Authority
HR
Croatia
Prior art keywords
acid
thp
optically active
process according
naproxen
Prior art date
Application number
HR20110941T
Other languages
English (en)
Croatian (hr)
Inventor
Segnalini Franca
Tuozzi Angela
Gentile Angelo
Original Assignee
Recordati Industria Chimica E Farmaceutica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Industria Chimica E Farmaceutica Spa filed Critical Recordati Industria Chimica E Farmaceutica Spa
Publication of HRP20110941T1 publication Critical patent/HRP20110941T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Steroid Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
HR20110941T 2008-02-28 2009-02-25 Postupak razdvajanja derivata izokinolina HRP20110941T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000319A ITMI20080319A1 (it) 2008-02-28 2008-02-28 Processo per la risoluzione di derivati isochinolinici
PCT/EP2009/052234 WO2009106547A1 (en) 2008-02-28 2009-02-25 Process for the resolution of isoquinoline derivatives

Publications (1)

Publication Number Publication Date
HRP20110941T1 true HRP20110941T1 (hr) 2012-03-31

Family

ID=40291711

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20110941T HRP20110941T1 (hr) 2008-02-28 2009-02-25 Postupak razdvajanja derivata izokinolina

Country Status (13)

Country Link
US (1) US8703955B2 (pl)
EP (1) EP2268617B1 (pl)
CN (1) CN101896462B (pl)
AT (1) ATE534631T1 (pl)
CA (1) CA2708666C (pl)
EA (1) EA017743B1 (pl)
ES (1) ES2375920T3 (pl)
HR (1) HRP20110941T1 (pl)
IL (1) IL206444A (pl)
IT (1) ITMI20080319A1 (pl)
PL (1) PL2268617T3 (pl)
SI (1) SI2268617T1 (pl)
WO (1) WO2009106547A1 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2125742A2 (en) * 2007-03-08 2009-12-02 Chemagis Ltd. (1r,1'r)-atracurium salts separation process
BRPI0808581A2 (pt) * 2007-03-26 2014-09-16 Chemagis Ltd "método para separar cisatracúrio com alta pureza de uma mistura de isômeros de (1r, 1'r) - atracúrio"
CA2685488A1 (en) * 2007-05-01 2008-11-06 Chemagis Ltd. Novel isoquinolinium compounds useful in the preparation of cisatracurium and associated intermediates
WO2008132748A1 (en) * 2007-05-01 2008-11-06 Chemagis Ltd. Process for producing cisatracurium compounds and associated intermediates
US8357805B2 (en) * 2007-06-18 2013-01-22 Chemagis Ltd. (1R,1′R)-atracurium salts separation process
CA2702535A1 (en) * 2007-10-29 2009-05-07 Chemagis Ltd. Novel r,r'-atracurium salts
CA2722651A1 (en) * 2008-05-01 2009-11-05 Chemagis Ltd. Cisatracurium derivatives, preparation and uses thereof
US8148527B1 (en) 2011-01-18 2012-04-03 Divi's Laboratories, Ltd. Resolution of 1-(4-methoxybenzyl)-octahydro-isoquinoline
CN103319406A (zh) * 2012-03-20 2013-09-25 迪维斯实验室有限公司 1-(4-甲氧苄基)-八氢-异喹啉的拆分
CN104610145B (zh) * 2015-01-27 2017-07-18 江苏嘉逸医药有限公司 苯磺顺阿曲库铵中间体r‑四氢罂粟碱‑n‑乙酰‑l‑亮氨酸盐的分离方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8418303D0 (en) * 1984-07-18 1984-08-22 Wellcome Found Compounds
DE19535762A1 (de) * 1995-09-26 1997-03-27 Basf Ag Verfahren zur Racematspaltung
DE19711739C1 (de) 1997-03-20 1998-08-20 Knorr Bremse Systeme Governor für Druckluftbeschaffungsanlagen von Fahrzeugen
US6670476B2 (en) * 2000-11-29 2003-12-30 Pfizer Inc. Resolution of trans-7-(hydroxy-methyl)octa-hydro-2H-pyrido[1,2-a]pyrazine
WO2006013581A2 (en) * 2004-08-02 2006-02-09 Matrix Laboratories Ltd Resolution of racemic organic acids with (1s, 4s)-4[3,4-dichlorophenyl]-1,2,3,4- tetrahydro-n-methyl-1-naphthaloneamine
KR20070080108A (ko) 2006-02-06 2007-08-09 주식회사종근당 질소의 알파 위치에 비대칭탄소가 있는 라세믹 유도체의광학 이성질체 분리 방법

Also Published As

Publication number Publication date
ES2375920T3 (es) 2012-03-07
PL2268617T3 (pl) 2012-05-31
IL206444A0 (en) 2010-12-30
CA2708666A1 (en) 2009-09-03
EA201071000A1 (ru) 2011-02-28
CN101896462A (zh) 2010-11-24
EP2268617B1 (en) 2011-11-23
US20100298570A1 (en) 2010-11-25
HK1150239A1 (en) 2011-11-11
SI2268617T1 (sl) 2012-05-31
CA2708666C (en) 2016-06-14
ITMI20080319A1 (it) 2009-08-29
US8703955B2 (en) 2014-04-22
IL206444A (en) 2013-10-31
WO2009106547A1 (en) 2009-09-03
EA017743B1 (ru) 2013-02-28
CN101896462B (zh) 2012-09-26
EP2268617A1 (en) 2011-01-05
ATE534631T1 (de) 2011-12-15

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