PL2262527T3 - Kompozycje do osiągania w surowicy pożądanych poziomów glejowego czynnika wzrostu 2 - Google Patents

Kompozycje do osiągania w surowicy pożądanych poziomów glejowego czynnika wzrostu 2

Info

Publication number
PL2262527T3
PL2262527T3 PL09715322T PL09715322T PL2262527T3 PL 2262527 T3 PL2262527 T3 PL 2262527T3 PL 09715322 T PL09715322 T PL 09715322T PL 09715322 T PL09715322 T PL 09715322T PL 2262527 T3 PL2262527 T3 PL 2262527T3
Authority
PL
Poland
Prior art keywords
compositions
growth factor
plasma levels
achieving desired
glial growth
Prior art date
Application number
PL09715322T
Other languages
English (en)
Other versions
PL2262527T4 (pl
Inventor
Haesun Kim
Anthony O. Caggiano
Original Assignee
Acorda Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acorda Therapeutics, Inc. filed Critical Acorda Therapeutics, Inc.
Publication of PL2262527T4 publication Critical patent/PL2262527T4/pl
Publication of PL2262527T3 publication Critical patent/PL2262527T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1883—Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/285—Demyelinating diseases; Multipel sclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
PL09715322T 2008-02-29 2009-03-02 Kompozycje do osiągania w surowicy pożądanych poziomów glejowego czynnika wzrostu 2 PL2262527T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6758908P 2008-02-29 2008-02-29
EP09715322.5A EP2262527B1 (en) 2008-02-29 2009-03-02 Compositions for achieving desired glial growth factor 2 plasma levels

Publications (2)

Publication Number Publication Date
PL2262527T4 PL2262527T4 (pl) 2017-07-31
PL2262527T3 true PL2262527T3 (pl) 2017-07-31

Family

ID=41016663

Family Applications (2)

Application Number Title Priority Date Filing Date
PL09715322T PL2262527T3 (pl) 2008-02-29 2009-03-02 Kompozycje do osiągania w surowicy pożądanych poziomów glejowego czynnika wzrostu 2
PL16182139.2T PL3120863T3 (pl) 2008-02-29 2009-03-02 Kompozycje do osiągnięcia pożądanych poziomów glejowego czynnika wzrostu 2 w osoczu

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL16182139.2T PL3120863T3 (pl) 2008-02-29 2009-03-02 Kompozycje do osiągnięcia pożądanych poziomów glejowego czynnika wzrostu 2 w osoczu

Country Status (11)

Country Link
US (5) US8410050B2 (pl)
EP (3) EP3750551A1 (pl)
JP (2) JP5697455B2 (pl)
CN (2) CN102026651B (pl)
AU (1) AU2009217606B2 (pl)
BR (1) BRPI0908271A2 (pl)
CA (1) CA2717193C (pl)
ES (2) ES2613177T3 (pl)
PL (2) PL2262527T3 (pl)
RU (3) RU2530650C2 (pl)
WO (1) WO2009108390A2 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2262527T3 (pl) 2008-02-29 2017-07-31 Acorda Therapeutics, Inc. Kompozycje do osiągania w surowicy pożądanych poziomów glejowego czynnika wzrostu 2
JP5797112B2 (ja) 2008-07-17 2015-10-21 アコーダ セラピューティクス インコーポレイテッド 心不全の治療または予防のためのニューレグリンまたはそのサブ配列の治療的投与方法
ES2609927T3 (es) 2008-08-15 2017-04-25 Acorda Therapeutics, Inc. Composiciones y métodos para tratamientos durante periodos no agudos después de lesiones neurológicas del SNC
JP5832437B2 (ja) 2009-10-14 2015-12-16 アコーダ セラピューティクス インコーポレイテッド 末梢神経損傷を処置するためのニューレグリンの使用
AU2011257192A1 (en) * 2010-05-28 2013-01-10 Mind-Nrg Sa Neuregulin isoforms, neuregulin polypeptides and uses thereof
WO2012021818A2 (en) * 2010-08-13 2012-02-16 Georgetown University Ggf2 and methods of use
DK3278811T3 (da) * 2012-03-30 2021-03-01 Acorda Therapeutics Inc Anvendelse af ggf2 til behandling af neuropatisk smerte ved peripheral nerveskade
US11207354B2 (en) * 2016-09-23 2021-12-28 Osaka University Schwann cell differentiation promoting agent and a peripheral nerve regeneration promoting agent
CN108653274B (zh) * 2017-04-01 2022-09-16 鲁南制药集团股份有限公司 牛蒡子苷元在制备治疗骨髓损伤药物中的用途

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7319019B1 (en) 1991-04-10 2008-01-15 Acorda Therapeutics, Inc. Glial mitogenic factors lacking an N-terminal signal sequence
US7135456B1 (en) * 1991-04-10 2006-11-14 Acorda Therapeutics, Inc. Glial mitogenic factors, their preparation and use
US5716930A (en) 1991-04-10 1998-02-10 Ludwig Institute For Cancer Research Glial growth factors
US5530109A (en) 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
US7037888B1 (en) * 1992-04-03 2006-05-02 Acorda Therapeutics, Inc. Methods for treating muscle diseases and disorders
GB9217316D0 (en) 1992-08-14 1992-09-30 Ludwig Inst Cancer Res Schwann cell mitogenic factor,its preparation and use
US5912326A (en) 1995-09-08 1999-06-15 President And Fellows Of Harvard College Cerebellum-derived growth factors
WO2001035899A2 (en) 1999-11-19 2001-05-25 Axxima Pharmaceuticals Ag Inhibitors of helicobacter pylori induced gastrointestinal diseases
US20030232761A1 (en) * 2002-03-28 2003-12-18 Hinke Simon A. Novel analogues of glucose-dependent insulinotropic polypeptide
EP1646353A4 (en) * 2003-05-16 2008-06-04 Acorda Therapeutics Inc FUSION PROTEINS FOR THE TREATMENT OF THE CNS
US20080213817A1 (en) * 2004-02-19 2008-09-04 Michael Karin Enhancement of Th2-Dependent and Inflammatory Response
WO2006084116A2 (en) 2005-02-02 2006-08-10 Nexuspharma Inc. Amine derivative containing compositions and methods for the treatment of viral infections related to the etiology of cancer
WO2007028085A2 (en) 2005-09-02 2007-03-08 Morehouse School Of Medicine Neuregulin for prevention and treatment of damage from acute assault on vascular and neuronal tissues
US20080003013A1 (en) * 2006-06-30 2008-01-03 Static Control Components, Inc. Cartridge split rail clip
PL2262527T3 (pl) 2008-02-29 2017-07-31 Acorda Therapeutics, Inc. Kompozycje do osiągania w surowicy pożądanych poziomów glejowego czynnika wzrostu 2
JP5431619B2 (ja) 2010-04-01 2014-03-05 ザ プロクター アンド ギャンブル カンパニー 柔軟仕上げ剤
WO2012021818A2 (en) 2010-08-13 2012-02-16 Georgetown University Ggf2 and methods of use

Also Published As

Publication number Publication date
AU2009217606A1 (en) 2009-09-03
CA2717193A1 (en) 2009-09-03
CA2717193C (en) 2022-08-16
CN102026651A (zh) 2011-04-20
EP2262527B1 (en) 2016-08-03
EP3120863A1 (en) 2017-01-25
RU2530650C2 (ru) 2014-10-10
US20180055909A1 (en) 2018-03-01
PL3120863T3 (pl) 2021-02-22
RU2010139906A (ru) 2012-04-10
PL2262527T4 (pl) 2017-07-31
BRPI0908271A2 (pt) 2017-06-13
US20210060128A1 (en) 2021-03-04
RU2019110452A (ru) 2020-10-09
US10675331B2 (en) 2020-06-09
US20130345131A1 (en) 2013-12-26
EP3120863B1 (en) 2020-05-06
JP5964920B2 (ja) 2016-08-03
US9744215B2 (en) 2017-08-29
EP3750551A1 (en) 2020-12-16
US20160367634A1 (en) 2016-12-22
CN104645315A (zh) 2015-05-27
WO2009108390A2 (en) 2009-09-03
JP5697455B2 (ja) 2015-04-08
EP2262527A2 (en) 2010-12-22
US9272015B2 (en) 2016-03-01
RU2687097C2 (ru) 2019-05-07
JP2011513310A (ja) 2011-04-28
ES2613177T3 (es) 2017-05-23
US20100029559A1 (en) 2010-02-04
AU2009217606B2 (en) 2015-03-05
US8410050B2 (en) 2013-04-02
WO2009108390A3 (en) 2010-11-18
JP2015042656A (ja) 2015-03-05
RU2014131265A (ru) 2016-02-20
CN102026651B (zh) 2015-06-03
ES2811127T3 (es) 2021-03-10

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