PL2262527T4 - Kompozycje do osiągania w surowicy pożądanych poziomów glejowego czynnika wzrostu 2 - Google Patents

Kompozycje do osiągania w surowicy pożądanych poziomów glejowego czynnika wzrostu 2

Info

Publication number
PL2262527T4
PL2262527T4 PL09715322T PL09715322T PL2262527T4 PL 2262527 T4 PL2262527 T4 PL 2262527T4 PL 09715322 T PL09715322 T PL 09715322T PL 09715322 T PL09715322 T PL 09715322T PL 2262527 T4 PL2262527 T4 PL 2262527T4
Authority
PL
Poland
Prior art keywords
compositions
growth factor
plasma levels
achieving desired
glial growth
Prior art date
Application number
PL09715322T
Other languages
English (en)
Other versions
PL2262527T3 (pl
Inventor
Haesun Kim
Anthony O. Caggiano
Original Assignee
Acorda Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acorda Therapeutics, Inc. filed Critical Acorda Therapeutics, Inc.
Publication of PL2262527T3 publication Critical patent/PL2262527T3/pl
Publication of PL2262527T4 publication Critical patent/PL2262527T4/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1883Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51Lyases (4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/4756Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/285Demyelinating diseases; Multipel sclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
PL09715322T 2008-02-29 2009-03-02 Kompozycje do osiągania w surowicy pożądanych poziomów glejowego czynnika wzrostu 2 PL2262527T4 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6758908P 2008-02-29 2008-02-29
EP09715322.5A EP2262527B1 (en) 2008-02-29 2009-03-02 Compositions for achieving desired glial growth factor 2 plasma levels

Publications (2)

Publication Number Publication Date
PL2262527T3 PL2262527T3 (pl) 2017-07-31
PL2262527T4 true PL2262527T4 (pl) 2017-07-31

Family

ID=41016663

Family Applications (2)

Application Number Title Priority Date Filing Date
PL09715322T PL2262527T4 (pl) 2008-02-29 2009-03-02 Kompozycje do osiągania w surowicy pożądanych poziomów glejowego czynnika wzrostu 2
PL16182139.2T PL3120863T3 (pl) 2008-02-29 2009-03-02 Kompozycje do osiągnięcia pożądanych poziomów glejowego czynnika wzrostu 2 w osoczu

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL16182139.2T PL3120863T3 (pl) 2008-02-29 2009-03-02 Kompozycje do osiągnięcia pożądanych poziomów glejowego czynnika wzrostu 2 w osoczu

Country Status (11)

Country Link
US (5) US8410050B2 (pl)
EP (3) EP2262527B1 (pl)
JP (2) JP5697455B2 (pl)
CN (2) CN102026651B (pl)
AU (1) AU2009217606B2 (pl)
BR (1) BRPI0908271A2 (pl)
CA (1) CA2717193C (pl)
ES (2) ES2613177T3 (pl)
PL (2) PL2262527T4 (pl)
RU (3) RU2530650C2 (pl)
WO (1) WO2009108390A2 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5697455B2 (ja) 2008-02-29 2015-04-08 アコーダ セラピューティクス インコーポレイテッド グリア成長因子2の所望の血漿レベルを達成するための方法
ES2763184T3 (es) 2008-07-17 2020-05-27 Acorda Therapeutics Inc Dosificación terapéutica de una neurregulina en el tratamiento o profilaxis de la insuficiencia cardíaca
ES2609927T3 (es) 2008-08-15 2017-04-25 Acorda Therapeutics, Inc. Composiciones y métodos para tratamientos durante periodos no agudos después de lesiones neurológicas del SNC
CA2777243A1 (en) 2009-10-14 2011-04-21 Acorda Therapeutics, Inc. Use of a neuregulin to treat peripheral nerve injury
MX2012013735A (es) * 2010-05-28 2013-04-29 Mind Nrg Sa Isoformas de neuregulina, polipeptidos de neuregulina y usos de los mismos.
JP2013535507A (ja) * 2010-08-13 2013-09-12 ジョージタウン ユニバーシティ Ggf2および使用方法
WO2013149163A1 (en) * 2012-03-30 2013-10-03 Acorda Therapeutics, Inc. Use of neuregulin to treat peripheral nerve injury
WO2018056412A1 (ja) * 2016-09-23 2018-03-29 国立大学法人大阪大学 シュワン細胞分化促進剤及び末梢神経再生促進剤
CN108653274B (zh) * 2017-04-01 2022-09-16 鲁南制药集团股份有限公司 牛蒡子苷元在制备治疗骨髓损伤药物中的用途

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7319019B1 (en) 1991-04-10 2008-01-15 Acorda Therapeutics, Inc. Glial mitogenic factors lacking an N-terminal signal sequence
US7135456B1 (en) 1991-04-10 2006-11-14 Acorda Therapeutics, Inc. Glial mitogenic factors, their preparation and use
US5530109A (en) 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
US5716930A (en) 1991-04-10 1998-02-10 Ludwig Institute For Cancer Research Glial growth factors
US7037888B1 (en) 1992-04-03 2006-05-02 Acorda Therapeutics, Inc. Methods for treating muscle diseases and disorders
GB9217316D0 (en) * 1992-08-14 1992-09-30 Ludwig Inst Cancer Res Schwann cell mitogenic factor,its preparation and use
US5912326A (en) 1995-09-08 1999-06-15 President And Fellows Of Harvard College Cerebellum-derived growth factors
AU3003701A (en) * 1999-11-19 2001-05-30 Axxima Pharmaceuticals Ag Inhibitors of helicobacter pylori induced gastrointestinal diseases
US20030232761A1 (en) 2002-03-28 2003-12-18 Hinke Simon A. Novel analogues of glucose-dependent insulinotropic polypeptide
EP2354155B1 (en) * 2003-05-16 2017-05-03 Acorda Therapeutics, Inc. Fusion Proteins for Treatment of CNS
WO2005079458A2 (en) * 2004-02-19 2005-09-01 The Regents Of The University Of California ENHANCEMENT OF Th2-DEPENDENT AND INFLAMMATORY RESPONSE
WO2006084116A2 (en) 2005-02-02 2006-08-10 Nexuspharma Inc. Amine derivative containing compositions and methods for the treatment of viral infections related to the etiology of cancer
US7776817B2 (en) 2005-09-02 2010-08-17 Morehouse School Of Medicine Neuregulins for prevention and treatment of damage from acute assault on vascular and neuronal tissue and as regulators of neuronal stem cell migration
US20080003013A1 (en) * 2006-06-30 2008-01-03 Static Control Components, Inc. Cartridge split rail clip
JP5697455B2 (ja) 2008-02-29 2015-04-08 アコーダ セラピューティクス インコーポレイテッド グリア成長因子2の所望の血漿レベルを達成するための方法
JP5431619B2 (ja) 2010-04-01 2014-03-05 ザ プロクター アンド ギャンブル カンパニー 柔軟仕上げ剤
JP2013535507A (ja) 2010-08-13 2013-09-12 ジョージタウン ユニバーシティ Ggf2および使用方法

Also Published As

Publication number Publication date
RU2019110452A (ru) 2020-10-09
CN102026651A (zh) 2011-04-20
CN104645315A (zh) 2015-05-27
WO2009108390A2 (en) 2009-09-03
JP2015042656A (ja) 2015-03-05
JP2011513310A (ja) 2011-04-28
CA2717193C (en) 2022-08-16
RU2010139906A (ru) 2012-04-10
PL2262527T3 (pl) 2017-07-31
AU2009217606B2 (en) 2015-03-05
EP2262527A2 (en) 2010-12-22
JP5964920B2 (ja) 2016-08-03
ES2811127T3 (es) 2021-03-10
US10675331B2 (en) 2020-06-09
PL3120863T3 (pl) 2021-02-22
RU2014131265A (ru) 2016-02-20
JP5697455B2 (ja) 2015-04-08
US20130345131A1 (en) 2013-12-26
EP3120863A1 (en) 2017-01-25
US20160367634A1 (en) 2016-12-22
EP2262527B1 (en) 2016-08-03
AU2009217606A1 (en) 2009-09-03
CA2717193A1 (en) 2009-09-03
US20100029559A1 (en) 2010-02-04
US20180055909A1 (en) 2018-03-01
US20210060128A1 (en) 2021-03-04
RU2687097C2 (ru) 2019-05-07
US9272015B2 (en) 2016-03-01
WO2009108390A3 (en) 2010-11-18
US8410050B2 (en) 2013-04-02
ES2613177T3 (es) 2017-05-23
RU2530650C2 (ru) 2014-10-10
US9744215B2 (en) 2017-08-29
EP3120863B1 (en) 2020-05-06
CN102026651B (zh) 2015-06-03
EP3750551A1 (en) 2020-12-16
BRPI0908271A2 (pt) 2017-06-13

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