PL2209795T3 - Aminoksymowe pochodne 2-i/lub 4-podstawionych androstanów i androstenów jako leki na zaburzenia sercowo-naczyniowe - Google Patents

Aminoksymowe pochodne 2-i/lub 4-podstawionych androstanów i androstenów jako leki na zaburzenia sercowo-naczyniowe

Info

Publication number
PL2209795T3
PL2209795T3 PL08804418T PL08804418T PL2209795T3 PL 2209795 T3 PL2209795 T3 PL 2209795T3 PL 08804418 T PL08804418 T PL 08804418T PL 08804418 T PL08804418 T PL 08804418T PL 2209795 T3 PL2209795 T3 PL 2209795T3
Authority
PL
Poland
Prior art keywords
androstenes
medicaments
cardiovascular disorders
aminooxime
derivatives
Prior art date
Application number
PL08804418T
Other languages
English (en)
Inventor
Alberto Cerri
Giuseppe Bianchi
Giorgio Fedrizzi
Patrizia Ferrari
Mauro Gobbini
Giuseppe Marazzi
Marco Torri
Walter Cabri
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of PL2209795T3 publication Critical patent/PL2209795T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016—Oximes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL08804418T 2007-10-12 2008-09-18 Aminoksymowe pochodne 2-i/lub 4-podstawionych androstanów i androstenów jako leki na zaburzenia sercowo-naczyniowe PL2209795T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07118362 2007-10-12
PCT/EP2008/062483 WO2009047101A1 (en) 2007-10-12 2008-09-18 Aminooxime derivatives of 2- and/or 4-substituted androstanes and androstenes as medicaments for cardiovascular disorders
EP08804418.5A EP2209795B1 (en) 2007-10-12 2008-09-18 Aminooxime derivatives of 2- and/or 4-substituted androstanes and androstenes as medicaments for cardiovascular disorders

Publications (1)

Publication Number Publication Date
PL2209795T3 true PL2209795T3 (pl) 2013-09-30

Family

ID=39351068

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08804418T PL2209795T3 (pl) 2007-10-12 2008-09-18 Aminoksymowe pochodne 2-i/lub 4-podstawionych androstanów i androstenów jako leki na zaburzenia sercowo-naczyniowe

Country Status (22)

Country Link
US (1) US8664210B2 (pl)
EP (1) EP2209795B1 (pl)
JP (1) JP5436432B2 (pl)
KR (1) KR101585275B1 (pl)
CN (1) CN101861328B (pl)
AR (1) AR068747A1 (pl)
AU (1) AU2008309791B2 (pl)
BR (1) BRPI0818540A2 (pl)
CA (1) CA2702111C (pl)
EA (1) EA017497B1 (pl)
ES (1) ES2412259T3 (pl)
HK (1) HK1148754A1 (pl)
IL (1) IL204957A (pl)
MX (1) MX2010003869A (pl)
MY (1) MY152099A (pl)
NZ (1) NZ584429A (pl)
PL (1) PL2209795T3 (pl)
PT (1) PT2209795E (pl)
SG (1) SG185288A1 (pl)
TW (1) TWI418354B (pl)
WO (1) WO2009047101A1 (pl)
ZA (1) ZA201003277B (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011284606A1 (en) 2010-07-30 2013-03-14 Pharmacellion Ltd Compounds and methods for treating neoplasia
CN112500311B (zh) * 2020-12-02 2023-03-24 河南普美济华医药科技有限公司 一种o-3-氯-2-丙烯基羟胺游离碱的制备工艺

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5144017A (en) * 1988-07-13 1992-09-01 University Of Manitoba Compounds that bind to digitalis receptor
DE19633349A1 (de) * 1996-08-19 1998-02-26 Sigma Tau Ind Farmaceuti Neue 6-Hydroxy- und 6-Oxo-androstan-Derivate, die auf das kardiovaskuläre System wirken und pharmazeutische Zusammensetzungen, die diese enthalten
IT1317031B1 (it) 2000-05-17 2003-05-26 Sigma Tau Ind Farmaceuti Procedimento migliorato per la preparazione di (e,z)3-(2-amminoetossimmino)-androstano-6, 17-dione e di suoi analoghi.

Also Published As

Publication number Publication date
SG185288A1 (en) 2012-11-29
EP2209795B1 (en) 2013-04-24
PT2209795E (pt) 2013-06-04
CA2702111A1 (en) 2009-04-16
EP2209795A1 (en) 2010-07-28
AU2008309791B2 (en) 2013-02-14
TWI418354B (zh) 2013-12-11
JP5436432B2 (ja) 2014-03-05
TW200930376A (en) 2009-07-16
US20100324003A1 (en) 2010-12-23
CA2702111C (en) 2015-11-24
EA201070459A1 (ru) 2010-10-29
CN101861328B (zh) 2014-08-13
MX2010003869A (es) 2010-04-27
BRPI0818540A2 (pt) 2015-06-16
AR068747A1 (es) 2009-12-02
IL204957A0 (en) 2010-11-30
AU2008309791A1 (en) 2009-04-16
JP2011500524A (ja) 2011-01-06
WO2009047101A1 (en) 2009-04-16
IL204957A (en) 2016-02-29
ZA201003277B (en) 2011-04-28
HK1148754A1 (en) 2011-09-16
NZ584429A (en) 2011-08-26
KR101585275B1 (ko) 2016-01-14
KR20100087162A (ko) 2010-08-03
EA017497B1 (ru) 2012-12-28
ES2412259T3 (es) 2013-07-10
CN101861328A (zh) 2010-10-13
US8664210B2 (en) 2014-03-04
MY152099A (en) 2014-08-15

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