PL2167095T3 - Związki fenotiazynowe do leczenia łagodnych zaburzeń poznawczych - Google Patents
Związki fenotiazynowe do leczenia łagodnych zaburzeń poznawczychInfo
- Publication number
- PL2167095T3 PL2167095T3 PL08762390T PL08762390T PL2167095T3 PL 2167095 T3 PL2167095 T3 PL 2167095T3 PL 08762390 T PL08762390 T PL 08762390T PL 08762390 T PL08762390 T PL 08762390T PL 2167095 T3 PL2167095 T3 PL 2167095T3
- Authority
- PL
- Poland
- Prior art keywords
- cognitive impairment
- mild cognitive
- treating mild
- phenothiazine compounds
- phenothiazine
- Prior art date
Links
- 208000010877 cognitive disease Diseases 0.000 title 1
- 208000027061 mild cognitive impairment Diseases 0.000 title 1
- 125000001484 phenothiazinyl group Chemical class C1(=CC=CC=2SC3=CC=CC=C3NC12)* 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94500607P | 2007-06-19 | 2007-06-19 | |
| PCT/GB2008/002066 WO2008155533A2 (en) | 2007-06-19 | 2008-06-17 | Phenothiazine compounds for treating mild cognitive impairment |
| EP08762390.6A EP2167095B1 (en) | 2007-06-19 | 2008-06-17 | Phenothiazine compounds for treating mild cognitive impairment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2167095T3 true PL2167095T3 (pl) | 2019-11-29 |
Family
ID=39943003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08762390T PL2167095T3 (pl) | 2007-06-19 | 2008-06-17 | Związki fenotiazynowe do leczenia łagodnych zaburzeń poznawczych |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US9211294B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2167095B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5725605B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN101820884B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008265045B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0813670A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2690746C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2167095T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2739546T3 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20191513T1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE045460T2 (cg-RX-API-DMAC7.html) |
| MY (1) | MY177001A (cg-RX-API-DMAC7.html) |
| PL (1) | PL2167095T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2167095T (cg-RX-API-DMAC7.html) |
| SI (1) | SI2167095T1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008155533A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109384741B (zh) | 2006-03-29 | 2023-01-06 | 维斯塔实验室有限公司 | 3,7-二氨基-10h-吩噻嗪化合物盐及其用途 |
| PL2205245T3 (pl) * | 2007-10-03 | 2015-12-31 | Wista Lab Ltd | Zastosowanie terapeutyczne diaminofenotiazyn |
| US8828986B2 (en) | 2011-04-20 | 2014-09-09 | Prosetta Antiviral Inc. | Antiviral compounds |
| JP5868955B2 (ja) | 2010-04-30 | 2016-02-24 | プロセッタ アンチバイラル インコーポレイテッド | 抗ウイルス化合物 |
| AU2011358840B2 (en) * | 2011-02-11 | 2017-05-04 | TauRx Therapeutics Management Ltd | Phenothiazine diaminium salts and their use |
| PL3470390T3 (pl) * | 2013-01-30 | 2023-11-06 | Ecolab Usa Inc. | Zmiatacze siarkowodoru |
| US10304006B2 (en) * | 2013-02-15 | 2019-05-28 | The Charles Stark Draper Laboratory, Inc. | Method for integrating and fusing heterogeneous data types to perform predictive analysis |
| WO2016133995A1 (en) * | 2015-02-17 | 2016-08-25 | Arizona Board Of Regents On Behalf Of Arizona State University | Phenothiazine analogues as mitochondrial therapeutic agents |
| EP4223297A3 (en) * | 2016-07-25 | 2023-11-15 | WisTa Laboratories Ltd. | Administration and dosage of diaminophenothiazines |
| GB201614834D0 (en) * | 2016-09-01 | 2016-10-19 | Wista Lab Ltd | Treatment of dementia |
| FI3826639T3 (fi) * | 2018-07-26 | 2024-10-30 | Wista Lab Ltd | Diaminofenotiatsiinien optimoitu annostus populaatioille |
| MY209608A (en) * | 2019-04-10 | 2025-07-24 | Genting Taurx Diagnostic Centre Sdn Bhd | Adaptive neurological testing method |
| GB201909454D0 (en) | 2019-07-01 | 2019-08-14 | Wista Lab Ltd | Enhancers |
| GB201909493D0 (en) | 2019-07-01 | 2019-08-14 | Wista Lab Ltd | Therapeutic interactions |
| GB201909506D0 (en) | 2019-07-02 | 2019-08-14 | Wista Lab Ltd | Synaptopathies |
| CA3257856A1 (en) | 2022-05-31 | 2023-12-07 | Wista Laboratories Ltd. | TREATMENT OF NEURODEGENERATIVE DISORDERS USING COMPOUNDS CONTAINING METHYLTHIONINIUM (MT) |
| AU2024231880A1 (en) | 2023-03-03 | 2025-09-11 | Taurx Therapeutics Management Ltd. | Diaminophenothiazine for the treatment of microvascular brain disease disease |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9506197D0 (en) * | 1995-03-27 | 1995-05-17 | Hoffmann La Roche | Inhibition of tau-tau association. |
| GB0017060D0 (en) * | 2000-07-11 | 2000-08-30 | Hunter Fleming Ltd | Production, stabilisation and use of reduced forms of pharmaceutical compounds |
| GB0101049D0 (en) * | 2001-01-15 | 2001-02-28 | Univ Aberdeen | Materials and methods relating to protein aggregation in neurodegenerative disease |
| WO2004087160A1 (en) * | 2003-04-03 | 2004-10-14 | Prana Biotechnology Ltd | Treatment of neurological conditions |
| PT1799662E (pt) * | 2004-09-23 | 2013-07-09 | Wista Lab Ltd | Métodos de síntese química e purificação de compostos de diaminofenotiazínio incluindo cloreto de metiltionínio (mtc) |
| CN101084204B (zh) * | 2004-09-23 | 2012-12-05 | 卫思道制药有限公司 | 包括亚甲蓝(mtc)在内的二氨基吩噻嗪鎓化合物的化学合成和纯化方法 |
| WO2006091728A2 (en) * | 2005-02-24 | 2006-08-31 | The Trustees Of The University Of Pennsylvania | Microtubule stabilizing compounds and methods of their use |
| EP2001556B1 (en) * | 2006-03-29 | 2014-10-01 | Wista Laboratories Ltd. | Thioninium compounds and their use |
| CN101460157B (zh) * | 2006-03-29 | 2015-09-02 | 维斯塔实验室有限公司 | 蛋白聚集抑制剂 |
| CN109384741B (zh) * | 2006-03-29 | 2023-01-06 | 维斯塔实验室有限公司 | 3,7-二氨基-10h-吩噻嗪化合物盐及其用途 |
| DK2457904T3 (en) | 2006-07-11 | 2015-01-12 | Wista Lab Ltd | Methods for the synthesis and / or purification of the compounds diaminophenothiazinium |
-
2008
- 2008-06-17 DK DK08762390.6T patent/DK2167095T3/da active
- 2008-06-17 MY MYPI20095255A patent/MY177001A/en unknown
- 2008-06-17 HU HUE08762390A patent/HUE045460T2/hu unknown
- 2008-06-17 PL PL08762390T patent/PL2167095T3/pl unknown
- 2008-06-17 SI SI200832080T patent/SI2167095T1/sl unknown
- 2008-06-17 PT PT08762390T patent/PT2167095T/pt unknown
- 2008-06-17 CN CN2008801031955A patent/CN101820884B/zh active Active
- 2008-06-17 BR BRPI0813670-0A2A patent/BRPI0813670A2/pt not_active Application Discontinuation
- 2008-06-17 CA CA2690746A patent/CA2690746C/en active Active
- 2008-06-17 ES ES08762390T patent/ES2739546T3/es active Active
- 2008-06-17 EP EP08762390.6A patent/EP2167095B1/en active Active
- 2008-06-17 US US12/665,608 patent/US9211294B2/en active Active
- 2008-06-17 AU AU2008265045A patent/AU2008265045B2/en active Active
- 2008-06-17 JP JP2010512761A patent/JP5725605B2/ja active Active
- 2008-06-17 WO PCT/GB2008/002066 patent/WO2008155533A2/en not_active Ceased
- 2008-06-17 HR HRP20191513 patent/HRP20191513T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101820884A (zh) | 2010-09-01 |
| SI2167095T1 (sl) | 2019-09-30 |
| WO2008155533A3 (en) | 2009-02-19 |
| MY177001A (en) | 2020-09-01 |
| JP5725605B2 (ja) | 2015-05-27 |
| PT2167095T (pt) | 2019-08-06 |
| EP2167095B1 (en) | 2019-05-29 |
| AU2008265045B2 (en) | 2014-02-27 |
| HUE045460T2 (hu) | 2019-12-30 |
| DK2167095T3 (da) | 2019-07-29 |
| BRPI0813670A2 (pt) | 2014-12-30 |
| US20100184752A1 (en) | 2010-07-22 |
| CN101820884B (zh) | 2013-08-28 |
| WO2008155533A2 (en) | 2008-12-24 |
| EP2167095A2 (en) | 2010-03-31 |
| CA2690746A1 (en) | 2008-12-24 |
| AU2008265045A1 (en) | 2008-12-24 |
| JP2010530403A (ja) | 2010-09-09 |
| CA2690746C (en) | 2018-01-02 |
| ES2739546T3 (es) | 2020-01-31 |
| HRP20191513T1 (hr) | 2019-11-29 |
| US9211294B2 (en) | 2015-12-15 |
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