PL2167085T3 - 4-[2-(4-metylofenylosulfanylo)fenylo]piperydyna do leczenia zespołu nadwrażliwości jelita grubego (ibs) - Google Patents

4-[2-(4-metylofenylosulfanylo)fenylo]piperydyna do leczenia zespołu nadwrażliwości jelita grubego (ibs)

Info

Publication number
PL2167085T3
PL2167085T3 PL08758225T PL08758225T PL2167085T3 PL 2167085 T3 PL2167085 T3 PL 2167085T3 PL 08758225 T PL08758225 T PL 08758225T PL 08758225 T PL08758225 T PL 08758225T PL 2167085 T3 PL2167085 T3 PL 2167085T3
Authority
PL
Poland
Prior art keywords
methylphenylsulfanyl
ibs
piperidine
phenyl
treatment
Prior art date
Application number
PL08758225T
Other languages
English (en)
Inventor
Silke Miller
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/DK2007/050076 external-priority patent/WO2007144006A1/en
Application filed by H Lundbeck As filed Critical H Lundbeck As
Priority claimed from PCT/DK2008/000216 external-priority patent/WO2008151632A1/en
Publication of PL2167085T3 publication Critical patent/PL2167085T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4465—Non condensed piperidines, e.g. piperocaine only substituted in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
PL08758225T 2007-03-20 2008-06-13 4-[2-(4-metylofenylosulfanylo)fenylo]piperydyna do leczenia zespołu nadwrażliwości jelita grubego (ibs) PL2167085T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200700423 2007-03-20
PCT/DK2007/050076 WO2007144006A1 (en) 2006-06-16 2007-06-15 Crystalline forms of 4- [2- (4-methylphenylsulfanyl) -phenyl] piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain
PCT/DK2008/000216 WO2008151632A1 (en) 2007-06-15 2008-06-13 4- [2- (4-methylphenylsulfanyl) phenyl] piperidine for the treatment of irritable bowel syndrome (ibs)
EP08758225.0A EP2167085B1 (en) 2007-03-20 2008-06-13 4- [2- (4-methylphenylsulfanyl) phenyl]piperidine for the treatment of irritable bowel syndrome (ibs)

Publications (1)

Publication Number Publication Date
PL2167085T3 true PL2167085T3 (pl) 2014-08-29

Family

ID=39575680

Family Applications (2)

Application Number Title Priority Date Filing Date
PL08715618T PL2139479T3 (pl) 2007-03-20 2008-03-14 4-[2-(4-Metylofenylosulfanylo)fenylo]piperydyna o połączonym hamowaniu wychwytu zwrotnego serotoniny i norepinefryny do leczenia ADHD, melancholii, depresji opornej na leczenie lub pozostałych objawów depresji
PL08758225T PL2167085T3 (pl) 2007-03-20 2008-06-13 4-[2-(4-metylofenylosulfanylo)fenylo]piperydyna do leczenia zespołu nadwrażliwości jelita grubego (ibs)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL08715618T PL2139479T3 (pl) 2007-03-20 2008-03-14 4-[2-(4-Metylofenylosulfanylo)fenylo]piperydyna o połączonym hamowaniu wychwytu zwrotnego serotoniny i norepinefryny do leczenia ADHD, melancholii, depresji opornej na leczenie lub pozostałych objawów depresji

Country Status (27)

Country Link
US (2) US20100144788A1 (pl)
EP (2) EP2139479B1 (pl)
JP (1) JP5388867B2 (pl)
KR (1) KR20090125775A (pl)
CN (2) CN101674830B (pl)
AR (1) AR065798A1 (pl)
AU (1) AU2008228639B2 (pl)
BR (1) BRPI0808831A2 (pl)
CA (1) CA2684556C (pl)
CL (1) CL2008000796A1 (pl)
CO (1) CO6220957A2 (pl)
CY (2) CY1113965T1 (pl)
DK (2) DK2139479T3 (pl)
EA (1) EA017407B1 (pl)
ES (2) ES2399305T3 (pl)
HR (1) HRP20130049T1 (pl)
IL (1) IL200954A (pl)
MX (1) MX2009009934A (pl)
MY (1) MY163537A (pl)
NZ (1) NZ579723A (pl)
PL (2) PL2139479T3 (pl)
PT (2) PT2139479E (pl)
RS (2) RS52676B (pl)
SI (1) SI2139479T1 (pl)
TW (1) TWI432194B (pl)
UA (2) UA97660C2 (pl)
WO (1) WO2008113360A2 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20110412T1 (hr) * 2006-06-16 2011-06-30 H. Lundbeck A/S Kristalni oblici 4-[2-4-(4-metilfenilsulfanil)fenil]piperidina sa kombiniranom inhibicijom reapsorpcije serotonina i norepinefrina za liječenje neuropatskih bolova
WO2008151632A1 (en) * 2007-06-15 2008-12-18 H.Lundbeck A/S 4- [2- (4-methylphenylsulfanyl) phenyl] piperidine for the treatment of irritable bowel syndrome (ibs)
TWI432194B (zh) 2007-03-20 2014-04-01 Lundbeck & Co As H ４-〔２-（４-甲基苯硫基）苯基〕哌啶之新穎治療用途
TW200938194A (en) * 2007-12-14 2009-09-16 Lundbeck & Co As H Therapeutic uses of compounds having affinity to the serotonin transporter, serotonin receptors and noradrenalin transporter
EP2564837B1 (en) * 2010-04-30 2019-01-30 Takeda Pharmaceutical Company Limited Enteric tablet
US8745134B1 (en) 2011-03-04 2014-06-03 Zynga Inc. Cross social network data aggregation
US8332488B1 (en) 2011-03-04 2012-12-11 Zynga Inc. Multi-level cache with synch
US8347322B1 (en) 2011-03-31 2013-01-01 Zynga Inc. Social network application programming interface
US10135776B1 (en) 2011-03-31 2018-11-20 Zynga Inc. Cross platform social networking messaging system
US8522137B1 (en) 2011-06-30 2013-08-27 Zynga Inc. Systems, methods, and machine readable media for social network application development using a custom markup language
WO2018002115A1 (en) 2016-07-01 2018-01-04 H. Lundbeck A/S Vortioxetine dosing regimes for fast onset of antidepressant effect
WO2020087031A1 (en) 2018-10-26 2020-04-30 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA004539B1 (ru) * 1998-05-22 2004-06-24 Эли Лилли Энд Компани Комбинационная терапия для лечения резистентной депрессии
UA81749C2 (uk) * 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну
SI1626720T1 (sl) * 2003-04-04 2008-12-31 Lundbeck & Co As H Derivati 4-(2-fenilsulfanil-fenil)-piperidina kotzaviralci ponovnega vnosa serotonina
JP2006522027A (ja) * 2003-04-04 2006-09-28 ハー・ルンドベック・アクチエゼルスカベット セロトニン再取り込み阻害剤としての４−（２−フェニルオキシフェニル）−ピペリジンまたは−１，２，３，６−テトラヒドロピリジン誘導体
AR052308A1 (es) * 2004-07-16 2007-03-14 Lundbeck & Co As H Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto
DE102006028034A1 (de) * 2006-06-14 2007-12-20 Leifheit Ag Bürste und Kehrgerät mit Bürste
HRP20110412T1 (hr) * 2006-06-16 2011-06-30 H. Lundbeck A/S Kristalni oblici 4-[2-4-(4-metilfenilsulfanil)fenil]piperidina sa kombiniranom inhibicijom reapsorpcije serotonina i norepinefrina za liječenje neuropatskih bolova
TWI405588B (zh) 2007-03-20 2013-08-21 Lundbeck & Co As H ４-〔２-（４-甲苯基硫基）-苯基〕哌啶之鹽類的液體調配物
TWI432194B (zh) 2007-03-20 2014-04-01 Lundbeck & Co As H ４-〔２-（４-甲基苯硫基）苯基〕哌啶之新穎治療用途
TW200938194A (en) * 2007-12-14 2009-09-16 Lundbeck & Co As H Therapeutic uses of compounds having affinity to the serotonin transporter, serotonin receptors and noradrenalin transporter

Also Published As

Publication number Publication date
CN101674830B (zh) 2012-05-09
CO6220957A2 (es) 2010-11-19
CN101674830A (zh) 2010-03-17
AU2008228639B2 (en) 2012-12-13
CN101646438B (zh) 2012-04-11
HK1142007A1 (en) 2010-11-26
PL2139479T3 (pl) 2013-05-31
MY163537A (en) 2017-09-15
EA200970871A1 (ru) 2010-04-30
HRP20130049T1 (hr) 2013-02-28
PT2139479E (pt) 2013-02-20
UA99611C2 (ru) 2012-09-10
RS53138B (sr) 2014-06-30
CY1114774T1 (el) 2016-12-14
SI2139479T1 (sl) 2013-04-30
WO2008113360A3 (en) 2008-11-13
EP2167085A1 (en) 2010-03-31
IL200954A0 (en) 2010-05-17
CY1113965T1 (el) 2016-07-27
CA2684556C (en) 2013-01-08
BRPI0808831A2 (pt) 2014-08-26
TW200848032A (en) 2008-12-16
EP2139479A2 (en) 2010-01-06
AU2008228639A1 (en) 2008-09-25
CA2684556A1 (en) 2008-09-25
US20100137366A1 (en) 2010-06-03
EA017407B1 (ru) 2012-12-28
TWI432194B (zh) 2014-04-01
UA97660C2 (ru) 2012-03-12
WO2008113360A2 (en) 2008-09-25
DK2139479T3 (da) 2013-02-11
MX2009009934A (es) 2009-09-24
DK2167085T3 (da) 2014-02-03
CL2008000796A1 (es) 2008-09-26
NZ579723A (en) 2011-07-29
AR065798A1 (es) 2009-07-01
CN101646438A (zh) 2010-02-10
KR20090125775A (ko) 2009-12-07
PT2167085E (pt) 2014-02-17
US20100144788A1 (en) 2010-06-10
RS52676B (sr) 2013-06-28
EP2139479B1 (en) 2012-12-12
JP5388867B2 (ja) 2014-01-15
JP2010521502A (ja) 2010-06-24
IL200954A (en) 2014-12-31
ES2445400T3 (es) 2014-03-03
US8507526B2 (en) 2013-08-13
EP2167085B1 (en) 2013-12-25
ES2399305T3 (es) 2013-03-27

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