PL2167085T3 - 4-[2-(4-metylofenylosulfanylo)fenylo]piperydyna do leczenia zespołu nadwrażliwości jelita grubego (ibs) - Google Patents

4-[2-(4-metylofenylosulfanylo)fenylo]piperydyna do leczenia zespołu nadwrażliwości jelita grubego (ibs)

Info

Publication number
PL2167085T3
PL2167085T3 PL08758225T PL08758225T PL2167085T3 PL 2167085 T3 PL2167085 T3 PL 2167085T3 PL 08758225 T PL08758225 T PL 08758225T PL 08758225 T PL08758225 T PL 08758225T PL 2167085 T3 PL2167085 T3 PL 2167085T3
Authority
PL
Poland
Prior art keywords
methylphenylsulfanyl
ibs
piperidine
phenyl
treatment
Prior art date
Application number
PL08758225T
Other languages
English (en)
Inventor
Silke Miller
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/DK2007/050076 external-priority patent/WO2007144006A1/en
Application filed by H Lundbeck As filed Critical H Lundbeck As
Priority claimed from PCT/DK2008/000216 external-priority patent/WO2008151632A1/en
Publication of PL2167085T3 publication Critical patent/PL2167085T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4465—Non condensed piperidines, e.g. piperocaine only substituted in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
PL08758225T 2007-03-20 2008-06-13 4-[2-(4-metylofenylosulfanylo)fenylo]piperydyna do leczenia zespołu nadwrażliwości jelita grubego (ibs) PL2167085T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200700423 2007-03-20
PCT/DK2007/050076 WO2007144006A1 (en) 2006-06-16 2007-06-15 Crystalline forms of 4- [2- (4-methylphenylsulfanyl) -phenyl] piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain
PCT/DK2008/000216 WO2008151632A1 (en) 2007-06-15 2008-06-13 4- [2- (4-methylphenylsulfanyl) phenyl] piperidine for the treatment of irritable bowel syndrome (ibs)
EP08758225.0A EP2167085B1 (en) 2007-03-20 2008-06-13 4- [2- (4-methylphenylsulfanyl) phenyl]piperidine for the treatment of irritable bowel syndrome (ibs)

Publications (1)

Publication Number Publication Date
PL2167085T3 true PL2167085T3 (pl) 2014-08-29

Family

ID=39575680

Family Applications (2)

Application Number Title Priority Date Filing Date
PL08715618T PL2139479T3 (pl) 2007-03-20 2008-03-14 4-[2-(4-Metylofenylosulfanylo)fenylo]piperydyna o połączonym hamowaniu wychwytu zwrotnego serotoniny i norepinefryny do leczenia ADHD, melancholii, depresji opornej na leczenie lub pozostałych objawów depresji
PL08758225T PL2167085T3 (pl) 2007-03-20 2008-06-13 4-[2-(4-metylofenylosulfanylo)fenylo]piperydyna do leczenia zespołu nadwrażliwości jelita grubego (ibs)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL08715618T PL2139479T3 (pl) 2007-03-20 2008-03-14 4-[2-(4-Metylofenylosulfanylo)fenylo]piperydyna o połączonym hamowaniu wychwytu zwrotnego serotoniny i norepinefryny do leczenia ADHD, melancholii, depresji opornej na leczenie lub pozostałych objawów depresji

Country Status (27)

Country Link
US (2) US20100144788A1 (pl)
EP (2) EP2139479B1 (pl)
JP (1) JP5388867B2 (pl)
KR (1) KR20090125775A (pl)
CN (2) CN101646438B (pl)
AR (1) AR065798A1 (pl)
AU (1) AU2008228639B2 (pl)
BR (1) BRPI0808831A2 (pl)
CA (1) CA2684556C (pl)
CL (1) CL2008000796A1 (pl)
CO (1) CO6220957A2 (pl)
CY (2) CY1113965T1 (pl)
DK (2) DK2139479T3 (pl)
EA (1) EA017407B1 (pl)
ES (2) ES2399305T3 (pl)
HR (1) HRP20130049T1 (pl)
IL (1) IL200954A (pl)
MX (1) MX2009009934A (pl)
MY (1) MY163537A (pl)
NZ (1) NZ579723A (pl)
PL (2) PL2139479T3 (pl)
PT (2) PT2139479E (pl)
RS (2) RS52676B (pl)
SI (1) SI2139479T1 (pl)
TW (1) TWI432194B (pl)
UA (2) UA97660C2 (pl)
WO (1) WO2008113360A2 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2044020T3 (pl) * 2006-06-16 2011-09-30 H Lundbeck As Krystaliczne postaci 4-[2-(4-metylofenylosulfanylo)-fenylo]piperydyny z równoczesnym hamowaniem wychwytu zwrotnego serotoniny i norepinefryny do leczenia bólu neuropatycznego
TWI432194B (zh) 2007-03-20 2014-04-01 Lundbeck & Co As H ４-〔２-（４-甲基苯硫基）苯基〕哌啶之新穎治療用途
SI2167085T1 (sl) * 2007-06-15 2014-05-30 H. Lundbeck A/S 4-(2-(4-metilfenilsulfanil)fenil)piperidin za zdravljenje sindroma razdraĺ˝ljivega äśrevesja (ibs)
TW200938194A (en) * 2007-12-14 2009-09-16 Lundbeck & Co As H Therapeutic uses of compounds having affinity to the serotonin transporter, serotonin receptors and noradrenalin transporter
ES2723029T3 (es) * 2010-04-30 2019-08-21 Takeda Pharmaceuticals Co Tableta entérica
US9311462B1 (en) * 2011-03-04 2016-04-12 Zynga Inc. Cross platform social networking authentication system
US8332488B1 (en) 2011-03-04 2012-12-11 Zynga Inc. Multi-level cache with synch
US10135776B1 (en) 2011-03-31 2018-11-20 Zynga Inc. Cross platform social networking messaging system
US8347322B1 (en) 2011-03-31 2013-01-01 Zynga Inc. Social network application programming interface
US8522137B1 (en) 2011-06-30 2013-08-27 Zynga Inc. Systems, methods, and machine readable media for social network application development using a custom markup language
EP3478289A1 (en) 2016-07-01 2019-05-08 H. Lundbeck A/S Vortioxetine dosing regimes for fast onset of antidepressant effect
WO2020087031A1 (en) 2018-10-26 2020-04-30 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0958824A3 (en) * 1998-05-22 1999-12-01 Eli Lilly And Company Olanzapine (zyprexa) in combination with fluoxetine (prozac), lithium or anticonvulsant for therapy of refractory depression
UA81749C2 (uk) 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну
PL1635828T3 (pl) * 2003-04-04 2008-10-31 H Lundbeck As Pochodne 4-(2-fenyloksyfenylo)-piperydyny lub 1,2,3,6-tetrahydropirydyny jako inhibitory wychwytu zwrotnego serotoniny
SI1626720T1 (sl) * 2003-04-04 2008-12-31 Lundbeck & Co As H Derivati 4-(2-fenilsulfanil-fenil)-piperidina kotzaviralci ponovnega vnosa serotonina
AR052308A1 (es) * 2004-07-16 2007-03-14 Lundbeck & Co As H Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto
DE102006028034A1 (de) * 2006-06-14 2007-12-20 Leifheit Ag Bürste und Kehrgerät mit Bürste
PL2044020T3 (pl) * 2006-06-16 2011-09-30 H Lundbeck As Krystaliczne postaci 4-[2-(4-metylofenylosulfanylo)-fenylo]piperydyny z równoczesnym hamowaniem wychwytu zwrotnego serotoniny i norepinefryny do leczenia bólu neuropatycznego
TWI432194B (zh) 2007-03-20 2014-04-01 Lundbeck & Co As H ４-〔２-（４-甲基苯硫基）苯基〕哌啶之新穎治療用途
TWI405588B (zh) 2007-03-20 2013-08-21 Lundbeck & Co As H ４-〔２-（４-甲苯基硫基）-苯基〕哌啶之鹽類的液體調配物
TW200938194A (en) * 2007-12-14 2009-09-16 Lundbeck & Co As H Therapeutic uses of compounds having affinity to the serotonin transporter, serotonin receptors and noradrenalin transporter

Also Published As

Publication number Publication date
HK1142007A1 (en) 2010-11-26
US20100137366A1 (en) 2010-06-03
EP2167085A1 (en) 2010-03-31
WO2008113360A2 (en) 2008-09-25
DK2167085T3 (da) 2014-02-03
AU2008228639A1 (en) 2008-09-25
US20100144788A1 (en) 2010-06-10
RS52676B (sr) 2013-06-28
JP5388867B2 (ja) 2014-01-15
EP2139479B1 (en) 2012-12-12
EA017407B1 (ru) 2012-12-28
TWI432194B (zh) 2014-04-01
AR065798A1 (es) 2009-07-01
KR20090125775A (ko) 2009-12-07
UA99611C2 (ru) 2012-09-10
NZ579723A (en) 2011-07-29
PL2139479T3 (pl) 2013-05-31
CA2684556C (en) 2013-01-08
HRP20130049T1 (hr) 2013-02-28
CY1113965T1 (el) 2016-07-27
DK2139479T3 (da) 2013-02-11
CN101646438B (zh) 2012-04-11
TW200848032A (en) 2008-12-16
JP2010521502A (ja) 2010-06-24
CL2008000796A1 (es) 2008-09-26
US8507526B2 (en) 2013-08-13
EP2139479A2 (en) 2010-01-06
IL200954A (en) 2014-12-31
SI2139479T1 (sl) 2013-04-30
PT2167085E (pt) 2014-02-17
PT2139479E (pt) 2013-02-20
BRPI0808831A2 (pt) 2014-08-26
AU2008228639B2 (en) 2012-12-13
EP2167085B1 (en) 2013-12-25
RS53138B (sr) 2014-06-30
CN101646438A (zh) 2010-02-10
WO2008113360A3 (en) 2008-11-13
CN101674830B (zh) 2012-05-09
MX2009009934A (es) 2009-09-24
CO6220957A2 (es) 2010-11-19
CA2684556A1 (en) 2008-09-25
CY1114774T1 (el) 2016-12-14
MY163537A (en) 2017-09-15
UA97660C2 (ru) 2012-03-12
CN101674830A (zh) 2010-03-17
ES2399305T3 (es) 2013-03-27
IL200954A0 (en) 2010-05-17
EA200970871A1 (ru) 2010-04-30
ES2445400T3 (es) 2014-03-03

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