PL2066638T3 - Sposób oczyszczania Montelukastu - Google Patents

Sposób oczyszczania Montelukastu

Info

Publication number
PL2066638T3
PL2066638T3 PL07788278T PL07788278T PL2066638T3 PL 2066638 T3 PL2066638 T3 PL 2066638T3 PL 07788278 T PL07788278 T PL 07788278T PL 07788278 T PL07788278 T PL 07788278T PL 2066638 T3 PL2066638 T3 PL 2066638T3
Authority
PL
Poland
Prior art keywords
montelukast
comprised
organic solvent
purification
impurities
Prior art date
Application number
PL07788278T
Other languages
English (en)
Inventor
Guillen Yolanda Gasanz
Llagostera Montserrat Monsalvatje
Escasany Pedro Talavera
Original Assignee
Esteve Quim S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Quim S A filed Critical Esteve Quim S A
Publication of PL2066638T3 publication Critical patent/PL2066638T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PL07788278T 2006-08-09 2007-08-07 Sposób oczyszczania Montelukastu PL2066638T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US83687306P 2006-08-09 2006-08-09
EP06118689A EP1886997A1 (en) 2006-08-09 2006-08-09 Process for the purification of montelukast
EP07788278A EP2066638B8 (en) 2006-08-09 2007-08-07 Process for the purification of montelukast
PCT/EP2007/058176 WO2008017667A1 (en) 2006-08-09 2007-08-07 Process for the purification of montelukast

Publications (1)

Publication Number Publication Date
PL2066638T3 true PL2066638T3 (pl) 2011-07-29

Family

ID=37667497

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07788278T PL2066638T3 (pl) 2006-08-09 2007-08-07 Sposób oczyszczania Montelukastu

Country Status (19)

Country Link
US (1) US20100029945A1 (pl)
EP (2) EP1886997A1 (pl)
JP (1) JP2010500324A (pl)
KR (1) KR20090037445A (pl)
CN (1) CN101490005B (pl)
AT (1) ATE499345T1 (pl)
AU (1) AU2007283613A1 (pl)
CA (1) CA2657017A1 (pl)
DE (1) DE602007012728D1 (pl)
ES (1) ES2361239T3 (pl)
HR (1) HRP20110322T1 (pl)
IL (1) IL195622A (pl)
MX (1) MX2008015135A (pl)
NO (1) NO20090748L (pl)
PL (1) PL2066638T3 (pl)
PT (1) PT2066638E (pl)
RU (1) RU2009108271A (pl)
SI (1) SI2066638T1 (pl)
WO (1) WO2008017667A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1652128B1 (en) 2003-07-07 2014-05-14 Insurance Services Office, Inc. Traffic information system
KR20090015186A (ko) 2005-07-05 2009-02-11 테바 파마슈티컬 인더스트리즈 리미티드 몬테루카스트의 정제
EP2552892A1 (en) 2010-03-31 2013-02-06 KRKA, D.D., Novo Mesto Efficient synthesis for the preparation of montelukast and novel crystalline form of intermediates therein
JP5553096B2 (ja) * 2012-08-29 2014-07-16 大日本印刷株式会社 高純度モンテルカストの製造法
CN103570619B (zh) * 2013-11-08 2015-12-09 南京靖龙药物研发有限公司 一种孟鲁司特钠衍生物的制备方法
CN105646344B (zh) * 2016-02-29 2018-08-14 山东新时代药业有限公司 一种孟鲁司特的纯化方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050107612A1 (en) * 2002-12-30 2005-05-19 Dr. Reddy's Laboratories Limited Process for preparation of montelukast and its salts
EP1708708A1 (en) * 2004-01-30 2006-10-11 Teva Pharmaceutical Industries Ltd. Montelukast free acid polymorphs
WO2005074893A1 (en) * 2004-02-03 2005-08-18 Chemagis Ltd. Stable amorphous forms of montelukast sodium
US7189853B2 (en) * 2004-04-15 2007-03-13 Dr. Reddy's Laboratories Limited Process for the preparation of [R-(E)-1-[[[1-[3-[2-[7-chloro-2-quinolinyl]ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid (Montelukast) and its pharmaceutically acceptable salts
CA2589936A1 (en) * 2004-11-30 2006-06-08 Medichem S.A. New process for the preparation of a leukotriene antagonist
WO2006064269A2 (en) * 2004-12-17 2006-06-22 Cipla Limited Salts of leukotriene antagonist montelukast

Also Published As

Publication number Publication date
CA2657017A1 (en) 2008-02-14
RU2009108271A (ru) 2010-09-20
DE602007012728D1 (de) 2011-04-07
IL195622A (en) 2011-03-31
EP2066638B8 (en) 2011-10-12
SI2066638T1 (sl) 2011-06-30
WO2008017667A1 (en) 2008-02-14
NO20090748L (no) 2009-03-09
ES2361239T3 (es) 2011-06-15
CN101490005A (zh) 2009-07-22
ATE499345T1 (de) 2011-03-15
JP2010500324A (ja) 2010-01-07
EP1886997A1 (en) 2008-02-13
HRP20110322T1 (hr) 2011-06-30
AU2007283613A1 (en) 2008-02-14
PT2066638E (pt) 2011-05-16
IL195622A0 (en) 2009-09-01
MX2008015135A (es) 2008-12-15
EP2066638A1 (en) 2009-06-10
AU2007283613A8 (en) 2009-01-22
US20100029945A1 (en) 2010-02-04
CN101490005B (zh) 2011-08-31
KR20090037445A (ko) 2009-04-15
EP2066638B1 (en) 2011-02-23

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