WO2005002523A3 - Process for preparing highly pure and free-flowing solid of 7-ethyltryptophol - Google Patents

Process for preparing highly pure and free-flowing solid of 7-ethyltryptophol Download PDF

Info

Publication number
WO2005002523A3
WO2005002523A3 PCT/US2004/021360 US2004021360W WO2005002523A3 WO 2005002523 A3 WO2005002523 A3 WO 2005002523A3 US 2004021360 W US2004021360 W US 2004021360W WO 2005002523 A3 WO2005002523 A3 WO 2005002523A3
Authority
WO
WIPO (PCT)
Prior art keywords
ethyltryptophol
free
highly pure
flowing solid
preparing highly
Prior art date
Application number
PCT/US2004/021360
Other languages
French (fr)
Other versions
WO2005002523A2 (en
Inventor
Taesoo Kwon
Hanrong Gao
Satish Bodige
Original Assignee
Sk Energy And Chemical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sk Energy And Chemical Inc filed Critical Sk Energy And Chemical Inc
Publication of WO2005002523A2 publication Critical patent/WO2005002523A2/en
Publication of WO2005002523A3 publication Critical patent/WO2005002523A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

An industrial purification process for preparing a highly pure and free-flowing solid of 7 -ethyl tryptophol. Crude 7-ethyltryptophol, prepared by kown procedures is dissolved in an organic solvent and washed with aqueous acid solutions to form an aqueous phase and an organic phase. After at least partially removing the solvelit from the organic phase, it is triturated with alkane solvent under cooling to silidify the residue. A highly pure and free-flowirig solid of 7-ethyltryptophol is recovered therefrom.
PCT/US2004/021360 2003-07-02 2004-07-02 Process for preparing highly pure and free-flowing solid of 7-ethyltryptophol WO2005002523A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48459803P 2003-07-02 2003-07-02
US60/484,598 2003-07-02

Publications (2)

Publication Number Publication Date
WO2005002523A2 WO2005002523A2 (en) 2005-01-13
WO2005002523A3 true WO2005002523A3 (en) 2005-07-28

Family

ID=33564008

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/021360 WO2005002523A2 (en) 2003-07-02 2004-07-02 Process for preparing highly pure and free-flowing solid of 7-ethyltryptophol

Country Status (1)

Country Link
WO (1) WO2005002523A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100439335C (en) * 2006-12-19 2008-12-03 浙江工业大学 Purifying process of 7-ethyl tryptol

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GARDEN ET AL.: "A versatile synthetic methodology fot the synthesis of tryptophols", TETRAHEDRON, vol. 58, 2002, pages 8399 - 8412, XP004388248 *

Also Published As

Publication number Publication date
WO2005002523A2 (en) 2005-01-13

Similar Documents

Publication Publication Date Title
CA2467001A1 (en) Extraction process for removal of impurities from mother liquor in the synthesis of carboxylic acid
CA2466999A1 (en) Extraction process for removal of impurities from mother liquor in the synthesis of carboxylic acid
TW200610568A (en) Extraction process for removal of impurities from an oxidizer purge stream in the synthesis of carboxylic acid
WO2008111589A1 (en) Method for production of purified anthocyanin
EP1167421A3 (en) Production process of polyphenylene ether
WO2009116729A3 (en) Method for refining of high purity of tacrolimus
NZ592385A (en) Highly purified polylactic acid or a derivative thereof, a salt of the same, and purification method thereof
EP1325943A3 (en) A method for the production of a lutein-fatty acid ester concentrate
WO2006061855A3 (en) Salts assisted selective extraction of 6-acetyl-4.1', 6' trichlorogalactosucrose and 4, 1 ', 6' trichlorogalactosucrose from aqueous reaction mixture
EP2066638B8 (en) Process for the purification of montelukast
EP1535893A4 (en) Process for producing (meth)acrylic acid compound
EP1866301B1 (en) Process for purifying thioctic acid in water
WO2005002523A3 (en) Process for preparing highly pure and free-flowing solid of 7-ethyltryptophol
CN103073458A (en) Method for recovering trifluoromethanesulfonic acid in wastewater
CN106045975A (en) A preparing method for high-purity ilaprazole sodium
AU2002220596A1 (en) Synthesis of r(+)alpha-lipoic acid
WO2005035487A8 (en) Process for purifying mesotrione
CN112079789A (en) Method for preparing isoxaflutole
WO2006026417A3 (en) Method for downhole sulfur removal and recovery
WO2008102375A3 (en) A process for preparation of highly pure isotretinoin
WO2013079507A3 (en) Method for producing and purifying salts of acrylamido-2-methylpropane sulfonic acid
WO2005012278A3 (en) Process for purifying citalopram using polybasic acids
WO2006027800A8 (en) A novel process for preparation of a pharmaceutically pure polymorphic form 1 of olanzapine
WO2002068330A3 (en) Process and apparatus for the production of calcium bromide by liquid-liquid extraction
EP1595862A4 (en) Process for production of iodine compounds and process for production of high-purity 5-iodo-2-methylbenzoic acid

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 20048188316

Country of ref document: CN

WWE Wipo information: entry into national phase

Ref document number: 1020067000089

Country of ref document: KR

WWE Wipo information: entry into national phase

Ref document number: 19/MUMNP/2006

Country of ref document: IN

122 Ep: pct application non-entry in european phase