WO2005002523A3 - Process for preparing highly pure and free-flowing solid of 7-ethyltryptophol - Google Patents

Process for preparing highly pure and free-flowing solid of 7-ethyltryptophol Download PDF

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Publication number
WO2005002523A3
WO2005002523A3 PCT/US2004/021360 US2004021360W WO2005002523A3 WO 2005002523 A3 WO2005002523 A3 WO 2005002523A3 US 2004021360 W US2004021360 W US 2004021360W WO 2005002523 A3 WO2005002523 A3 WO 2005002523A3
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WO
WIPO (PCT)
Prior art keywords
ethyltryptophol
free
highly pure
flowing solid
preparing highly
Prior art date
Application number
PCT/US2004/021360
Other languages
French (fr)
Other versions
WO2005002523A2 (en
Inventor
Taesoo Kwon
Hanrong Gao
Satish Bodige
Original Assignee
Sk Energy And Chemical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sk Energy And Chemical Inc filed Critical Sk Energy And Chemical Inc
Publication of WO2005002523A2 publication Critical patent/WO2005002523A2/en
Publication of WO2005002523A3 publication Critical patent/WO2005002523A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

An industrial purification process for preparing a highly pure and free-flowing solid of 7 -ethyl tryptophol. Crude 7-ethyltryptophol, prepared by kown procedures is dissolved in an organic solvent and washed with aqueous acid solutions to form an aqueous phase and an organic phase. After at least partially removing the solvelit from the organic phase, it is triturated with alkane solvent under cooling to silidify the residue. A highly pure and free-flowirig solid of 7-ethyltryptophol is recovered therefrom.
PCT/US2004/021360 2003-07-02 2004-07-02 Process for preparing highly pure and free-flowing solid of 7-ethyltryptophol WO2005002523A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48459803P 2003-07-02 2003-07-02
US60/484,598 2003-07-02

Publications (2)

Publication Number Publication Date
WO2005002523A2 WO2005002523A2 (en) 2005-01-13
WO2005002523A3 true WO2005002523A3 (en) 2005-07-28

Family

ID=33564008

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/021360 WO2005002523A2 (en) 2003-07-02 2004-07-02 Process for preparing highly pure and free-flowing solid of 7-ethyltryptophol

Country Status (1)

Country Link
WO (1) WO2005002523A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100439335C (en) * 2006-12-19 2008-12-03 浙江工业大学 Purifying process of 7-ethyl tryptol

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GARDEN ET AL.: "A versatile synthetic methodology fot the synthesis of tryptophols", TETRAHEDRON, vol. 58, 2002, pages 8399 - 8412, XP004388248 *

Also Published As

Publication number Publication date
WO2005002523A2 (en) 2005-01-13

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