PL1963288T3 - Podstawione pochodne oksazolu - Google Patents

Podstawione pochodne oksazolu

Info

Publication number
PL1963288T3
PL1963288T3 PL06841029T PL06841029T PL1963288T3 PL 1963288 T3 PL1963288 T3 PL 1963288T3 PL 06841029 T PL06841029 T PL 06841029T PL 06841029 T PL06841029 T PL 06841029T PL 1963288 T3 PL1963288 T3 PL 1963288T3
Authority
PL
Poland
Prior art keywords
alkyl
optionally substituted
aryl
optionally
attached
Prior art date
Application number
PL06841029T
Other languages
English (en)
Other versions
PL1963288T4 (pl
Inventor
Beatrix Merla
Stefan Oberbörsch
Bernd Sundermann
Werner Englberger
Heinz Graubaum
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of PL1963288T3 publication Critical patent/PL1963288T3/pl
Publication of PL1963288T4 publication Critical patent/PL1963288T4/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/48Nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36Opioid-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PL06841029T 2005-12-22 2006-12-19 Podstawione pochodne oksazolu PL1963288T4 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005061429A DE102005061429A1 (de) 2005-12-22 2005-12-22 Substituierte Oxazol-Derivate
EP06841029A EP1963288B1 (de) 2005-12-22 2006-12-19 Substituierte oxazol-derivate mit analgetischer wirkung
PCT/EP2006/012222 WO2007079928A1 (de) 2005-12-22 2006-12-19 Substituierte oxazol-derivate mit analgetischer wirkung

Publications (2)

Publication Number Publication Date
PL1963288T3 true PL1963288T3 (pl) 2012-01-31
PL1963288T4 PL1963288T4 (pl) 2012-03-30

Family

ID=37814593

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06841029T PL1963288T4 (pl) 2005-12-22 2006-12-19 Podstawione pochodne oksazolu

Country Status (17)

Country Link
US (1) US7608619B2 (pl)
EP (1) EP1963288B1 (pl)
JP (1) JP2009520718A (pl)
CN (1) CN101384563B (pl)
AT (1) ATE523501T1 (pl)
AU (1) AU2006334744B2 (pl)
CA (1) CA2634566A1 (pl)
CY (1) CY1112176T1 (pl)
DE (1) DE102005061429A1 (pl)
DK (1) DK1963288T3 (pl)
ES (1) ES2370660T3 (pl)
IL (1) IL192269A0 (pl)
PL (1) PL1963288T4 (pl)
PT (1) PT1963288E (pl)
RU (1) RU2424236C2 (pl)
SI (1) SI1963288T1 (pl)
WO (1) WO2007079928A1 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005061430A1 (de) * 2005-12-22 2007-07-05 Grünenthal GmbH Substituierte Imidazolin-Derivate
PL2260042T3 (pl) 2008-03-27 2012-02-29 Gruenenthal Gmbh Podstawione spirocykliczne pochodne cykloheksanu
MX2010010407A (es) 2008-03-27 2010-10-25 Gruenenthal Gmbh Derivados de 4-aminociclohexanos sustituidos.
PE20091823A1 (es) 2008-03-27 2009-12-10 Gruenenthal Chemie Ciclohexildiaminas sustituidas
DK2257526T3 (da) 2008-03-27 2012-02-06 Gruenenthal Gmbh Spiro(5,5)undecan-derivater
RU2514192C2 (ru) 2008-03-27 2014-04-27 Грюненталь Гмбх Гидроксиметилциклогексиламины
WO2009118163A1 (de) 2008-03-27 2009-10-01 Grünenthal GmbH (hetero-)aryl-cyclohexan-derivate

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19525137C2 (de) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbin -dungen als Zwischenprodukte zur Herstellung pharmazeutischer Wirkstoffe
DE19609847A1 (de) * 1996-03-13 1997-09-18 Gruenenthal Gmbh Dimethyl-(3-aryl-but-3-enyl)-aminverbindungen als pharmazeutische Wirkstoffe
DE19732928C2 (de) * 1997-07-31 2000-05-18 Gruenenthal Gmbh Verwendung substituierter Imidazolidin-2,4-dion-Verbindungen als Schmerzmittel
AU9034798A (en) * 1997-08-28 1999-03-16 Eli Lilly And Company Method for treating pain
US5952360A (en) * 1997-08-28 1999-09-14 Eli Lilly And Company Method for treating neuropathic pain
DE19858593A1 (de) * 1998-12-18 2000-06-21 Merck Patent Gmbh Sulfonyloxazolamine als therapeutische Wirkstoffe
EP1486490A1 (en) * 2002-02-28 2004-12-15 Takeda Chemical Industries, Ltd. Azole compounds
TW200505446A (en) * 2003-01-17 2005-02-16 Fuj Isawa Pharmaceutical Co Ltd Inhibitor of cox

Also Published As

Publication number Publication date
AU2006334744A1 (en) 2007-07-19
IL192269A0 (en) 2008-12-29
HK1123297A1 (en) 2009-06-12
CA2634566A1 (en) 2007-07-19
PT1963288E (pt) 2011-11-04
US20090069330A1 (en) 2009-03-12
EP1963288A1 (de) 2008-09-03
DE102005061429A1 (de) 2007-06-28
WO2007079928A1 (de) 2007-07-19
SI1963288T1 (sl) 2011-12-30
CY1112176T1 (el) 2015-12-09
CN101384563B (zh) 2012-06-27
ATE523501T1 (de) 2011-09-15
ES2370660T3 (es) 2011-12-21
CN101384563A (zh) 2009-03-11
RU2008129625A (ru) 2010-02-27
DK1963288T3 (da) 2011-11-21
PL1963288T4 (pl) 2012-03-30
US7608619B2 (en) 2009-10-27
RU2424236C2 (ru) 2011-07-20
JP2009520718A (ja) 2009-05-28
AU2006334744B2 (en) 2011-06-16
EP1963288B1 (de) 2011-09-07

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