PL1817006T3 - Liposomalny preparat do doustnego podawania glutationu (zredukowanego) - Google Patents

Liposomalny preparat do doustnego podawania glutationu (zredukowanego)

Info

Publication number
PL1817006T3
PL1817006T3 PL05851408T PL05851408T PL1817006T3 PL 1817006 T3 PL1817006 T3 PL 1817006T3 PL 05851408 T PL05851408 T PL 05851408T PL 05851408 T PL05851408 T PL 05851408T PL 1817006 T3 PL1817006 T3 PL 1817006T3
Authority
PL
Poland
Prior art keywords
glutathione
reduced
oral administration
liposomal formulation
liposomal
Prior art date
Application number
PL05851408T
Other languages
English (en)
Polish (pl)
Inventor
F Timothy Guilford
Original Assignee
F Timothy Guilford
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Timothy Guilford filed Critical F Timothy Guilford
Publication of PL1817006T3 publication Critical patent/PL1817006T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A61K38/063—Glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL05851408T 2004-11-07 2005-11-07 Liposomalny preparat do doustnego podawania glutationu (zredukowanego) PL1817006T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US52278504P 2004-11-07 2004-11-07
US59499605P 2005-05-25 2005-05-25
US59704105P 2005-11-06 2005-11-06
PCT/US2005/040308 WO2006060120A2 (en) 2004-11-07 2005-11-07 Liposomal formulation for oral administration of glutathione (reduced)
EP05851408A EP1817006B1 (en) 2004-11-07 2005-11-07 Liposomal formulation for oral administration of glutathione (reduced)

Publications (1)

Publication Number Publication Date
PL1817006T3 true PL1817006T3 (pl) 2013-03-29

Family

ID=36565495

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05851408T PL1817006T3 (pl) 2004-11-07 2005-11-07 Liposomalny preparat do doustnego podawania glutationu (zredukowanego)

Country Status (7)

Country Link
EP (1) EP1817006B1 (https=)
JP (2) JP5112876B2 (https=)
CA (1) CA2628777C (https=)
ES (1) ES2395555T3 (https=)
IL (1) IL182950A (https=)
PL (1) PL1817006T3 (https=)
WO (1) WO2006060120A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1868572A4 (en) * 2005-03-29 2011-03-09 F Timothy Guilford ADMINISTRATION OF GLUTATHION (REDUCED) ON THE INTRAVENOUS WAY OR CAPSULATED IN A LIPOSOME FOR THE TREATMENT OF TNF ALPHA EFFECTS AND FLUID VIRAL SYMPTOMS
WO2011036557A1 (en) * 2009-09-22 2011-03-31 The University Of British Columbia Compositions and methods for enhancing cellular uptake and intracellular delivery of lipid particles
WO2011082283A2 (en) * 2009-12-30 2011-07-07 Guilford F Timothy Management of myoclonus with oral liposomal reduced glutathione
WO2012094033A1 (en) 2011-01-05 2012-07-12 Livon Laboratories Methods of making liposomes, liposome compositions made by the methods, and methods of using the same
WO2013103840A1 (en) * 2012-01-05 2013-07-11 Guilford Frederick Timothy Anti-cancer composition and method utilizing 3-bp and liposomal reduced glutathione
WO2013109421A1 (en) * 2012-01-05 2013-07-25 Guilford Frederick Timothy Liposomally encapsulated reduced glutathione for management of cancer and disruption of cancer energy cycles
WO2014070769A1 (en) 2012-10-29 2014-05-08 The University Of North Carolina At Chapel Hill Methods and compositions for treating mucosal tissue disorders
WO2014126594A1 (en) * 2013-02-15 2014-08-21 Guilford Frederick Timothy Treatment of evolving bacterial resistance diseases including klebsiella pneumoniae with liposomally formulated glutathione
TWI589308B (zh) 2014-03-25 2017-07-01 林信湧 一種用於治療帕金森氏症之吸入式醫藥組成物及其備製方法
AU2017362500B2 (en) 2016-11-17 2024-09-26 Renovion, Inc. Treatment of Respiratory Tract Diseases and Infections with Ascorbic Acid Compositions
BR112020009910A2 (pt) 2017-11-17 2020-11-03 Renovion, Inc. composições de ácido ascórbico estáveis e métodos de usar as mesmas
KR102171719B1 (ko) 2018-11-14 2020-10-29 충남대학교산학협력단 경구투여용 글루타치온 함유 프로리포좀, 이를 포함하는 약제학적 조성물 및 이의 제조방법
KR20240131358A (ko) 2022-01-04 2024-08-30 레노비온, 아이엔씨. 글루타치온 염을 포함하는 수용액

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5746921A (en) * 1980-09-02 1982-03-17 Green Cross Corp:The Oral preparation of human blood coagulation factor
FR2609393A1 (fr) * 1988-02-23 1988-07-15 Serobiologiques Lab Sa Composition notamment utile comme matiere de base pour la preparation de compositions pharmaceutiques, notamment dermatologiques et/ou cosmetiques comprenant une substance azotee, notamment aminoacides, oligo- ou polypeptides, proteines, et leurs derives, et composition pharmaceutique ou cosmetique ainsi preparee.
US5238683A (en) * 1989-11-24 1993-08-24 The United States Of America As Represented By The Department Of Health And Human Services Aerosol preparation of glutathione and a method for augmenting glutathione level in lungs
JP3272736B2 (ja) * 1991-01-31 2002-04-08 協和醗酵工業株式会社 リポソーム製剤
IT1257697B (it) * 1992-04-24 1996-02-01 Lifegroup Spa N-acil derivati di aminoalcooli come agenti terapeutici attivi sull'edema neurogenico endoneurale a livello del nervo periferico.
US6764693B1 (en) * 1992-12-11 2004-07-20 Amaox, Ltd. Free radical quenching composition and a method to increase intracellular and/or extracellular antioxidants
US5607969A (en) * 1992-12-24 1997-03-04 Yissum Research Development Company Of The Hebrew University Of Jerusalem L-DOPA ethyl ester to treat Parkinson's disease
JPH0859503A (ja) * 1994-08-26 1996-03-05 Teijin Ltd ペプチド・蛋白質性薬物の経口、経粘膜投与用リポソーム製剤
US5500232A (en) * 1994-10-06 1996-03-19 Bristol-Myers Squibb Company Calcium fortified beverages
US5891465A (en) * 1996-05-14 1999-04-06 Biozone Laboratories, Inc. Delivery of biologically active material in a liposomal formulation for administration into the mouth
GB9620504D0 (en) * 1996-10-02 1996-11-20 Boehringer Ingelheim Ltd Compositions
US6369106B1 (en) * 1996-12-26 2002-04-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Treatment of ischemic brain injuries with brain targeted anti oxidant compounds
DE69739663D1 (de) * 1996-12-31 2009-12-31 Antioxidant Pharmaceuticals Co Pharmazeutische glutathionpräparate und methoden zu dern verabreichung
US6756056B2 (en) * 1997-04-08 2004-06-29 Alan A. Rubin Treatment of Parkinson's disease and related disorders by novel formulations of the combination carbidopa-levodopa
US6470894B2 (en) * 1997-09-19 2002-10-29 Thione International, Inc. Glutathione, green tea, grape seed extract to neutralize tobacco free radicals
US5829449A (en) * 1997-09-19 1998-11-03 Thione International, Inc. Smoking products containing antioxidants
US5994323A (en) * 1997-12-31 1999-11-30 P.N. Gerolymatos S.A. Pharmaceutical compositions comprising clioquinol in combination with vitamin B12 and therapeutic and prophylactic uses thereof
US6350470B1 (en) * 1998-04-29 2002-02-26 Cima Labs Inc. Effervescent drug delivery system for oral administration
FR2777781B1 (fr) * 1998-04-24 2004-04-09 Rhone Poulenc Rorer Sa Associations riluzole et l-dopa pour le traitement de la maladie de parkinson
US6011067A (en) * 1999-06-11 2000-01-04 Thione International, Inc. Antioxidant composition for the treatment of psoriasis and related diseases
JP3989803B2 (ja) * 2002-09-18 2007-10-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 食品腐敗菌の増殖抑制方法

Also Published As

Publication number Publication date
EP1817006A4 (en) 2009-12-02
JP2012102138A (ja) 2012-05-31
JP2008518976A (ja) 2008-06-05
ES2395555T3 (es) 2013-02-13
WO2006060120A3 (en) 2006-09-14
CA2628777C (en) 2016-09-13
CA2628777A1 (en) 2006-06-08
JP5571706B2 (ja) 2014-08-13
EP1817006B1 (en) 2012-09-05
JP5112876B2 (ja) 2013-01-09
WO2006060120A2 (en) 2006-06-08
EP1817006A2 (en) 2007-08-15
IL182950A (en) 2013-10-31
IL182950A0 (en) 2007-08-19

Similar Documents

Publication Publication Date Title
IL182950A0 (en) Liposomal formulation for oral administration of glutathione (reduced)
IL182967A0 (en) Liposomal formulation of bortezomib (ps-341)
AU2003268087A1 (en) Liposomal gemcitabine compositions for better drug delivery
IL173808A0 (en) Pharmaceutical liposomal formulations
IL176519A0 (en) Directly compressible pharmaceutical composition for the oral administration of cci-779
AU2003246978A1 (en) Pharmaceutical compositions comprising cyclosporin for oral administration
EP1757273A4 (en) PREPARATION FOR ORAL ADMINISTRATION
IL177402A0 (en) Composition for oral administration of tamsulosin hydrochloride
EP1755633A4 (en) ORAL ADMINISTRATION OF PEPTIDE PHARMACEUTICAL COMPOSITIONS
IL180031A0 (en) Stable pharmaceutical formulations of benzimidazole compounds
IL166337A0 (en) Oral administration of calctionin
AU2003280387A1 (en) Pharmaceutical formulation comprising azithrocycin monohydrate
AU2003284786A8 (en) Microemulsion composition for oral administration of biphenyldimethyldicarboxylate
EP1626697A4 (en) PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION WITH LITHIUM CARBONATE
IL175556A0 (en) Pharmaceutical composition for oral administration of a pyrazol-3-carboxamide derivative
ZA200706110B (en) Pharmaceutical formulations of gallium salts
PL373776A1 (en) Oral pharmaceutical compound
GB0413138D0 (en) Preparation for oral administration
HK1110008A (en) Liposomal formulation of bortezomib (ps-341)
GB0225702D0 (en) Oral formulation of moisutre-sensitive drugs
AU2003254672A1 (en) Dual-spike release formulation for oral drug delivery
HK1098970A (en) Stable pharmaceutical formulations of benzimidazole compounds
HK1072196A (en) Oral administration of interferon-tau
AU2002346284A1 (en) Pharmaceutical compositions of phospholipid derivatives
IL189956A0 (en) Methods and compositions for oral administration of proteins