PL1778621T3 - Wytwarzanie jodiksanolu - Google Patents
Wytwarzanie jodiksanoluInfo
- Publication number
- PL1778621T3 PL1778621T3 PL05771995T PL05771995T PL1778621T3 PL 1778621 T3 PL1778621 T3 PL 1778621T3 PL 05771995 T PL05771995 T PL 05771995T PL 05771995 T PL05771995 T PL 05771995T PL 1778621 T3 PL1778621 T3 PL 1778621T3
- Authority
- PL
- Poland
- Prior art keywords
- iodixanol
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO20043305A NO20043305D0 (no) | 2004-08-09 | 2004-08-09 | Preparation of lodixanol |
EP05771995A EP1778621B1 (en) | 2004-08-09 | 2005-08-08 | Preparation of iodixanol |
PCT/NO2005/000287 WO2006016815A1 (en) | 2004-08-09 | 2005-08-08 | Preparation of iodixanol |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1778621T3 true PL1778621T3 (pl) | 2012-11-30 |
Family
ID=35013342
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL05771995T PL1778621T3 (pl) | 2004-08-09 | 2005-08-08 | Wytwarzanie jodiksanolu |
Country Status (15)
Country | Link |
---|---|
US (1) | US8445724B2 (pl) |
EP (1) | EP1778621B1 (pl) |
JP (1) | JP5048490B2 (pl) |
KR (1) | KR101188596B1 (pl) |
CN (1) | CN101001831B (pl) |
AU (1) | AU2005272229B2 (pl) |
BR (1) | BRPI0514169A (pl) |
CA (1) | CA2575088C (pl) |
ES (1) | ES2386792T3 (pl) |
MX (1) | MX2007001624A (pl) |
NO (1) | NO20043305D0 (pl) |
PL (1) | PL1778621T3 (pl) |
PT (1) | PT1778621E (pl) |
RU (1) | RU2385316C2 (pl) |
WO (1) | WO2006016815A1 (pl) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO342021B1 (no) * | 2005-07-29 | 2018-03-12 | Ge Healthcare As | Kontinuerlig krystalliseringsprosess |
NO20053676D0 (no) | 2005-07-29 | 2005-07-29 | Amersham Health As | Crystallisation Process |
NO20055643D0 (no) * | 2005-11-29 | 2005-11-29 | Amersham Health As | Preparation of lodixanol |
PL1966110T3 (pl) | 2005-12-19 | 2013-09-30 | Ge Healthcare As | Sposób oczyszczania jodiksanolu |
US8969619B2 (en) * | 2009-07-21 | 2015-03-03 | Ge Healthcare As | Synthesis of iodixanol in propyleneglycol |
US7999135B2 (en) * | 2009-07-21 | 2011-08-16 | Ge Healthcare As | Crystallization of iodixanol using ultrasound |
US8962886B2 (en) * | 2009-07-21 | 2015-02-24 | Ge Healthcare As | Synthesis of iodixanol in methanol |
US7754918B1 (en) * | 2009-07-21 | 2010-07-13 | Ge Healthcare As | Crystallization of iodixanol in isopropanol and methanol |
US7999134B2 (en) * | 2009-07-21 | 2011-08-16 | Ge Healthcare As | Crystallization of iodixanol using milling |
US8962887B2 (en) * | 2009-07-21 | 2015-02-24 | Ge Healthcare As | Synthesis of iodixanol in 1-methoxy-2-propanol and water or methanol |
ES2607481T3 (es) | 2009-11-26 | 2017-03-31 | Imax Diagnostic Imaging Holding Limited | Preparación y purificación de iodixanol |
GB2496971A (en) * | 2011-11-25 | 2013-05-29 | Ge Healthcare As | Preparation of X-ray contrast agents |
CN110003038A (zh) * | 2012-09-27 | 2019-07-12 | 通用电气医疗集团股份有限公司 | Ioforminol的中间体化合物的制备 |
RU2642436C2 (ru) * | 2012-09-27 | 2018-01-25 | ДжиИ Хелткер АС | Получение иоформинола - рентгеноконтрастного агента |
PL2917174T3 (pl) * | 2012-11-12 | 2019-01-31 | Ge Healthcare As | Wytwarzanie związków pośrednich dla rentgenowskich środków kontrastowych |
KR102180250B1 (ko) | 2012-12-19 | 2020-11-18 | 지이 헬스케어 에이에스 | X-선 조영제 성분의 정제 방법 |
CN111777525B (zh) * | 2019-04-04 | 2021-08-27 | 成都西岭源药业有限公司 | 一种碘克沙醇的精制方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9720969D0 (en) * | 1997-10-02 | 1997-12-03 | Nycomed Imaging As | Process |
ITMI20010773A1 (it) | 2001-04-11 | 2002-10-11 | Chemi Spa | Processo per la produzione di ioexolo ad elevata purezza |
NO20053687D0 (no) * | 2005-07-29 | 2005-07-29 | Amersham Health As | Crystallisation Process. |
-
2004
- 2004-08-09 NO NO20043305A patent/NO20043305D0/no unknown
-
2005
- 2005-08-08 RU RU2007104091/04A patent/RU2385316C2/ru active
- 2005-08-08 PL PL05771995T patent/PL1778621T3/pl unknown
- 2005-08-08 AU AU2005272229A patent/AU2005272229B2/en not_active Ceased
- 2005-08-08 JP JP2007525566A patent/JP5048490B2/ja active Active
- 2005-08-08 CN CN2005800269464A patent/CN101001831B/zh active Active
- 2005-08-08 KR KR1020077003077A patent/KR101188596B1/ko active IP Right Grant
- 2005-08-08 US US11/573,283 patent/US8445724B2/en active Active
- 2005-08-08 BR BRPI0514169-9A patent/BRPI0514169A/pt not_active Application Discontinuation
- 2005-08-08 MX MX2007001624A patent/MX2007001624A/es active IP Right Grant
- 2005-08-08 CA CA2575088A patent/CA2575088C/en not_active Expired - Fee Related
- 2005-08-08 EP EP05771995A patent/EP1778621B1/en active Active
- 2005-08-08 WO PCT/NO2005/000287 patent/WO2006016815A1/en active Application Filing
- 2005-08-08 PT PT05771995T patent/PT1778621E/pt unknown
- 2005-08-08 ES ES05771995T patent/ES2386792T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
AU2005272229A1 (en) | 2006-02-16 |
ES2386792T3 (es) | 2012-08-30 |
NO20043305D0 (no) | 2004-08-09 |
PT1778621E (pt) | 2012-07-13 |
CN101001831A (zh) | 2007-07-18 |
EP1778621A1 (en) | 2007-05-02 |
RU2385316C2 (ru) | 2010-03-27 |
CN101001831B (zh) | 2011-08-03 |
JP2008509214A (ja) | 2008-03-27 |
CA2575088C (en) | 2012-10-30 |
CA2575088A1 (en) | 2006-02-16 |
KR20070057793A (ko) | 2007-06-07 |
US8445724B2 (en) | 2013-05-21 |
AU2005272229B2 (en) | 2011-04-28 |
BRPI0514169A (pt) | 2008-06-03 |
JP5048490B2 (ja) | 2012-10-17 |
WO2006016815A1 (en) | 2006-02-16 |
KR101188596B1 (ko) | 2012-10-05 |
MX2007001624A (es) | 2008-10-27 |
EP1778621B1 (en) | 2012-06-13 |
US20090253935A1 (en) | 2009-10-08 |
RU2007104091A (ru) | 2008-09-20 |
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