PL1625153T3 - Acylowane nonadepsipeptydy typu lizobaktyny - Google Patents

Acylowane nonadepsipeptydy typu lizobaktyny

Info

Publication number
PL1625153T3
PL1625153T3 PL04729639T PL04729639T PL1625153T3 PL 1625153 T3 PL1625153 T3 PL 1625153T3 PL 04729639 T PL04729639 T PL 04729639T PL 04729639 T PL04729639 T PL 04729639T PL 1625153 T3 PL1625153 T3 PL 1625153T3
Authority
PL
Poland
Prior art keywords
nonadepsipeptides
lysobactin
acylated
type
type nonadepsipeptides
Prior art date
Application number
PL04729639T
Other languages
English (en)
Inventor
Nussbaum Franz Von
Nina Brunner
Sonja Anlauf
Rainer Endermann
Chantal Fürstner
Elke Hartmann
Johannes Köbberling
Jacques Ragot
Guido Schiffer
Joachim Schuhmacher
Niels Svenstrup
Joachim Telser
Michael-Alexander Brüning
Original Assignee
Aicuris Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aicuris Gmbh & Co Kg filed Critical Aicuris Gmbh & Co Kg
Publication of PL1625153T3 publication Critical patent/PL1625153T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043Leu-amino acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C07K5/06069Ser-amino acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
PL04729639T 2003-05-09 2004-04-27 Acylowane nonadepsipeptydy typu lizobaktyny PL1625153T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10320781A DE10320781A1 (de) 2003-05-09 2003-05-09 Acylierte Nonadepsipeptide
EP04729639A EP1625153B1 (de) 2003-05-09 2004-04-27 Acylierte nonadepsipeptide vom lysobactin-typ
PCT/EP2004/004416 WO2004099239A1 (de) 2003-05-09 2004-04-27 Acylierte nonadepsipeptide vom lysobactin-typ

Publications (1)

Publication Number Publication Date
PL1625153T3 true PL1625153T3 (pl) 2010-02-26

Family

ID=33394366

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04729639T PL1625153T3 (pl) 2003-05-09 2004-04-27 Acylowane nonadepsipeptydy typu lizobaktyny

Country Status (16)

Country Link
US (1) US7368424B2 (pl)
EP (1) EP1625153B1 (pl)
JP (1) JP4557232B2 (pl)
AR (1) AR044256A1 (pl)
AT (1) ATE440859T1 (pl)
CA (1) CA2524722A1 (pl)
CL (1) CL2004000979A1 (pl)
DE (2) DE10320781A1 (pl)
DK (1) DK1625153T3 (pl)
ES (1) ES2330221T3 (pl)
GT (1) GT200400090A (pl)
PL (1) PL1625153T3 (pl)
PT (1) PT1625153E (pl)
TW (1) TW200510449A (pl)
UY (1) UY28313A1 (pl)
WO (1) WO2004099239A1 (pl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10320781A1 (de) * 2003-05-09 2004-11-25 Bayer Healthcare Ag Acylierte Nonadepsipeptide
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7772271B2 (en) 2004-07-14 2010-08-10 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7868037B2 (en) 2004-07-14 2011-01-11 Ptc Therapeutics, Inc. Methods for treating hepatitis C
WO2006019831A1 (en) 2004-07-14 2006-02-23 Ptc Therapeutics, Inc. Methods for treating hepatitis c
JP2008507518A (ja) 2004-07-22 2008-03-13 ピーティーシー セラピューティクス,インコーポレーテッド C型肝炎を治療するためのチエノピリジン
DE102004051025A1 (de) * 2004-10-20 2006-04-27 Bayer Healthcare Ag Substituierte Nonadepsipeptide
DE102004051024A1 (de) * 2004-10-20 2006-04-27 Bayer Healthcare Ag Heterocyclyl-substituierte Nonadepsipeptide
DE102004051023A1 (de) 2004-10-20 2006-05-04 Bayer Healthcare Ag Desoxo-Nonadepsipeptide
DE102004053409A1 (de) * 2004-11-05 2006-05-11 Bayer Healthcare Ag Verfahren zur gezielten Herstellung von Lysobactinfragmenten
DE102004053407A1 (de) * 2004-11-05 2006-05-11 Bayer Healthcare Ag Acylierte Nonadepsipeptide II
DE102004053410A1 (de) * 2004-11-05 2006-05-11 Bayer Healthcare Ag Cyclische Nonadepsipeptidamide
DE102006003443A1 (de) * 2006-01-25 2007-07-26 Aicuris Gmbh & Co. Kg Asparagin-10-substituierte Nonadepsipeptide
DE102006018250A1 (de) * 2006-04-13 2007-10-18 Aicuris Gmbh & Co. Kg Verfahren zum Herstellen von cyclischen Depsipeptiden
DE102006018080A1 (de) 2006-04-13 2007-10-18 Aicuris Gmbh & Co. Kg Lysobactinamide
US8853439B2 (en) 2009-09-25 2014-10-07 Cadila Healthcare Limited Processes for the preparation of lacosamide and intermediates thereof
TW201717991A (zh) * 2015-08-17 2017-06-01 拜耳動物保健有限公司 用於治療牛乳房炎之溶桿菌素
EP3363452A1 (en) 2017-02-17 2018-08-22 Bayer Animal Health GmbH Combinations of lysobactin and aminogylcosides against diseases caused by gram-positive and gram-negative bacteria in non-human animals

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1266247C (en) * 1985-03-25 1990-02-27 ANTIBIOTIC PREPARED BY LYSOBACTER SP. SC14.067
JPH01132600A (ja) 1987-11-17 1989-05-25 Shionogi & Co Ltd カタノシンaおよびbならびにその製造法
DE10320781A1 (de) * 2003-05-09 2004-11-25 Bayer Healthcare Ag Acylierte Nonadepsipeptide

Also Published As

Publication number Publication date
JP2007535469A (ja) 2007-12-06
ES2330221T3 (es) 2009-12-07
PT1625153E (pt) 2009-11-03
DK1625153T3 (da) 2009-12-14
UY28313A1 (es) 2004-12-31
ATE440859T1 (de) 2009-09-15
TW200510449A (en) 2005-03-16
EP1625153A1 (de) 2006-02-15
GT200400090A (es) 2004-12-23
US7368424B2 (en) 2008-05-06
CL2004000979A1 (es) 2005-05-06
DE502004009971D1 (de) 2009-10-08
WO2004099239A1 (de) 2004-11-18
AR044256A1 (es) 2005-09-07
EP1625153B1 (de) 2009-08-26
DE10320781A1 (de) 2004-11-25
CA2524722A1 (en) 2004-11-18
JP4557232B2 (ja) 2010-10-06
US20050075281A1 (en) 2005-04-07

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