PH9423A - Imidazole derivatives - Google Patents

Imidazole derivatives

Info

Publication number
PH9423A
PH9423A PH8144*UA PH8144A PH9423A PH 9423 A PH9423 A PH 9423A PH 8144 A PH8144 A PH 8144A PH 9423 A PH9423 A PH 9423A
Authority
PH
Philippines
Prior art keywords
imidazole derivatives
imidazole
derivatives
Prior art date
Application number
PH8144*UA
Other languages
English (en)
Inventor
R Duschinsky
W Tautz
A Beaman
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PH9423A publication Critical patent/PH9423A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fats And Perfumes (AREA)
PH8144*UA 1966-04-18 1967-04-12 Imidazole derivatives PH9423A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54306666A 1966-04-18 1966-04-18
US85755669A 1969-09-12 1969-09-12

Publications (1)

Publication Number Publication Date
PH9423A true PH9423A (en) 1975-11-14

Family

ID=27067226

Family Applications (1)

Application Number Title Priority Date Filing Date
PH8144*UA PH9423A (en) 1966-04-18 1967-04-12 Imidazole derivatives

Country Status (14)

Country Link
US (2) US3505349A (de)
BE (1) BE696952A (de)
CH (3) CH561698A5 (de)
DE (1) DE1695186B2 (de)
DK (1) DK137854B (de)
ES (1) ES339419A1 (de)
FI (1) FI49037C (de)
FR (1) FR6767M (de)
GB (1) GB1138529A (de)
IL (1) IL27805A (de)
NL (1) NL150787B (de)
NO (1) NO124072B (de)
PH (1) PH9423A (de)
SE (1) SE346001B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1079275B (de) * 1958-09-05 1960-04-07 Praemeta Praez Smetall Und Kun Schnepper, insbesondere zur Blutentnahme
FR2054504B1 (de) * 1969-07-18 1973-06-08 Rhone Poulenc Sa
DE2022206C3 (de) * 1970-05-06 1979-01-25 Bayer Ag, 5090 Leverkusen Basisch substituierte Diphenylazolyl-essigsäureester, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US3940484A (en) * 1971-12-07 1976-02-24 The Boots Company Limited Insecticidal compositions and methods of combatting insects using substituted imidazoles
DE2306495A1 (de) * 1973-02-09 1974-08-15 Bayer Ag Fungizide mittel
DE2553021A1 (de) * 1974-12-06 1976-06-10 Sandoz Ag Organische verbindungen, ihre verwendung und herstellung
IE47132B1 (en) * 1977-08-19 1983-12-28 Roche Products Ltd Novel nitroimidazoles and pharmaceutical preparations containing these as well as their manufacture
DE3070778D1 (en) * 1979-08-11 1985-07-25 Bayer Ag Antimycotic agents with enhanced release of the active ingredients
US4371540A (en) * 1979-09-14 1983-02-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Nitroimidazoles of low toxicity and high activity as radiosensitizers of hypoxic tumor cells
ZW8781A1 (en) * 1980-05-23 1981-12-16 Hoffmann La Roche 2-nitroimidazoles and preparation thereof
US5192784A (en) * 1991-06-03 1993-03-09 Du Pont Merck Pharmaceutical Company Etanidazole injectable solution
US5366987A (en) * 1991-08-22 1994-11-22 Warner-Lambert Company Isoxazolyl-substituted alkyl amide ACAT inhibitors
CA2149770C (en) * 1992-11-19 2009-01-06 Cameron J. Koch Detection of hypoxia
US6252087B1 (en) * 1992-11-19 2001-06-26 The Trustees Of The University Of Pennsylvania Nitroaromatic compounds for the detection of hypoxia
US6855828B1 (en) 1992-11-19 2005-02-15 The Trustees Of The University Of Pennsylvania Detection of hypoxia
US5721265A (en) * 1994-08-05 1998-02-24 Sri International Fluorinated 2-nitroimidazole analogs for detecting hypoxic tumor cells
US20050026974A1 (en) * 1996-02-08 2005-02-03 Trustees Of The University Of Pennsylvania Detection of hypoxia
ES2340912T3 (es) * 1999-07-21 2010-06-11 The Trustees Of The University Of Pennsylvania Preparacion de compuestos utiles para la deteccion de hipoxia.
US7230115B1 (en) 1999-07-21 2007-06-12 The Trustees Of The University Of Pennsylvania Preparation of compounds useful for the detection of hypoxia
MX2008013238A (es) * 2006-04-12 2008-10-21 Merck & Co Inc Antagonistas de los canales de calcio de tipo t de piridil amida.
EP2212293A4 (de) * 2007-10-24 2010-12-01 Merck Sharp & Dohme Heterocyclische amid-calciumkanalantagonisten vom typ t
JP5524071B2 (ja) * 2007-10-24 2014-06-18 メルク・シャープ・アンド・ドーム・コーポレーション 複素環フェニルアミドｔ型カルシウムチャネルアンタゴニスト
WO2013122112A1 (ja) * 2012-02-13 2013-08-22 国立大学法人筑波大学 ニトロイミダゾールを用いたプロドラッグ
SV2013004584A (es) * 2013-11-19 2015-09-07 Mini De Educacion Procedimiento de manufactura para obtención de de n-bencil-2-(2-nitro-1h-imidazol-1-il)acetamida
WO2017205622A1 (en) * 2016-05-25 2017-11-30 Savant Neglected Diseases, Llc Method of making benznidazole
WO2019240671A1 (es) * 2018-06-11 2019-12-19 Ministerio De Educación, Ciencia Y Tecnología Método de manufactura para la producción de benznidazol y su escalado industrial

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3065133A (en) * 1956-09-28 1962-11-20 Rhone Poulenc Sa Imidazoles for the control of histomoniasis
US3037909A (en) * 1960-06-29 1962-06-05 Merck & Co Inc 1-methyl-5-nitroimidazole for enterohepatitis
NL299109A (de) * 1962-11-05

Also Published As

Publication number Publication date
NL150787B (nl) 1976-09-15
FR6767M (de) 1969-03-10
NL6705439A (de) 1967-10-19
DK137854C (de) 1978-10-23
DE1695186A1 (de) 1971-04-08
NO124072B (de) 1972-02-28
US3679698A (en) 1972-07-25
IL27805A (en) 1972-04-27
CH553787A (de) 1974-09-13
ES339419A1 (es) 1968-05-16
DK137854B (da) 1978-05-22
CH565771A5 (de) 1975-08-29
FI49037B (de) 1974-12-02
US3505349A (en) 1970-04-07
CH561698A5 (de) 1975-05-15
DE1695186B2 (de) 1976-12-02
SE346001B (de) 1972-06-19
BE696952A (de) 1967-10-13
FI49037C (fi) 1975-03-10
GB1138529A (en) 1969-01-01

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