PH26714A - Novel human TNF polypeptide mutants and DNAs encoding said mutants - Google Patents
Novel human TNF polypeptide mutants and DNAs encoding said mutants Download PDFInfo
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- PH26714A PH26714A PH35431A PH35431A PH26714A PH 26714 A PH26714 A PH 26714A PH 35431 A PH35431 A PH 35431A PH 35431 A PH35431 A PH 35431A PH 26714 A PH26714 A PH 26714A
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- Philippines
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- tnf
- polypeptide
- replaced
- leu
- pro
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14557586 | 1986-06-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
PH26714A true PH26714A (en) | 1992-09-15 |
Family
ID=15388278
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH35431A PH26714A (en) | 1986-06-20 | 1987-07-19 | Novel human TNF polypeptide mutants and DNAs encoding said mutants |
Country Status (10)
Country | Link |
---|---|
US (1) | US4990455A (fr) |
EP (1) | EP0251037B1 (fr) |
KR (1) | KR880000471A (fr) |
AT (1) | ATE107362T1 (fr) |
AU (1) | AU592196B2 (fr) |
DE (1) | DE3750056T2 (fr) |
DK (1) | DK312387A (fr) |
HU (1) | HU210118B (fr) |
PH (1) | PH26714A (fr) |
SU (1) | SU1762761A3 (fr) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0247906B1 (fr) * | 1986-02-04 | 1994-12-28 | Mizuno, Den'Ichi | ADN codant pour des polypeptides antitumoraux, les polypeptides et les agents antitumoraux contenant ces polypeptides |
DE3716513A1 (de) * | 1987-05-16 | 1988-11-24 | Basf Ag | Proteine mit tnf-wirkung |
DE3837012A1 (de) * | 1988-01-15 | 1989-07-27 | Knoll Ag | Verwendung von tnf und lt zur herstellung von arzneimitteln |
JPH0797997B2 (ja) * | 1988-04-28 | 1995-10-25 | 帝人株式会社 | 新規生理活性ポリペプチド |
DE3843534A1 (de) * | 1988-12-23 | 1990-07-12 | Basf Ag | Neue tnf-polypeptide |
DE3922089A1 (de) * | 1989-05-09 | 1990-12-13 | Basf Ag | Neue proteine und ihre herstellung |
US6232446B1 (en) | 1989-05-18 | 2001-05-15 | Yeda Research And Development Co. Ltd. | TNF ligands |
US6262239B1 (en) | 1989-05-18 | 2001-07-17 | Yeda Research And Development Co., Ltd. | TNF receptor-specific antibodies |
ATE199398T1 (de) * | 1989-10-24 | 2001-03-15 | Chiron Corp | Sekretion vom mit gamma-interferon signalpeptid gebundenen humänen protein |
US5519119A (en) * | 1990-09-21 | 1996-05-21 | Ishihara Sangyo Kaisha Ltd. | Muteins of TNF pharmaceutical compositions and a method of making |
US5653974A (en) * | 1990-10-18 | 1997-08-05 | Board Of Regents,The University Of Texas System | Preparation and characterization of liposomal formulations of tumor necrosis factor |
CA2055168A1 (fr) * | 1990-11-21 | 1992-05-22 | Walter Fiers | Muteines de tnf |
KR970005042B1 (ko) * | 1993-02-09 | 1997-04-11 | 한일합성섬유공업 주식회사 | 종양괴사인자-알파 뮤테인 |
CA2119089A1 (fr) * | 1993-03-29 | 1994-09-30 | David Banner | Muteines du facteur de necrose tumoral |
US5888814A (en) * | 1994-06-06 | 1999-03-30 | Chiron Corporation | Recombinant host cells encoding TNF proteins |
US6184344B1 (en) * | 1995-05-04 | 2001-02-06 | The Scripps Research Institute | Synthesis of proteins by native chemical ligation |
US7070771B1 (en) | 1996-12-09 | 2006-07-04 | Regents Of The University Of California | Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells |
PL194221B1 (pl) * | 1997-04-15 | 2007-05-31 | Pharmexa As | Zmodyfikowana cząsteczka ludzkiego TNFalfa, dimery, oligomery lub multimery zmodyfikowanej cząsteczki ludzkiego TNFalfa, wyizolowana cząsteczka DNA, wektor, wektor ekspresyjny, komórka gospodarza, sposób wytwarzania zmodyfikowanej cząsteczki ludzkiego TNFalfa, szczepionki przeciwko TNFalfa oraz zastosowanie przynajmniej jednej zmodyfikowanej cząsteczki ludzkiego TNFalfa |
US7101974B2 (en) | 2000-03-02 | 2006-09-05 | Xencor | TNF-αvariants |
US7687461B2 (en) | 2000-03-02 | 2010-03-30 | Xencor, Inc. | Treatment of TNF-α related disorders with TNF-α variant proteins |
US7446174B2 (en) | 2001-03-02 | 2008-11-04 | Xencor, Inc. | Protein based TNF-α variants for the treatment of TNF-α related disorders |
US20070172449A1 (en) * | 2000-03-02 | 2007-07-26 | Xencor, Inc. | TNF-alpha VARIANT FORMULATIONS FOR THE TREATMENT OF TNF-alpha RELATED DISORDERS |
US7056695B2 (en) | 2000-03-02 | 2006-06-06 | Xencor | TNF-α variants |
US7244823B2 (en) * | 2000-03-02 | 2007-07-17 | Xencor | TNF-alpha variants proteins for the treatment of TNF-alpha related disorders |
US7662367B2 (en) | 2000-03-02 | 2010-02-16 | Xencor, Inc. | Pharmaceutical compositions for the treatment of TNF-α related disorders |
US7786282B2 (en) * | 2001-12-06 | 2010-08-31 | The Regents Of The University Of California | Nucleic acid molecules encoding TNF-α ligand polypeptides having a CD154 domain |
KR100475403B1 (ko) * | 2002-05-28 | 2005-03-15 | 재단법인서울대학교산학협력재단 | 반도체 배선용 구리 박막 형성방법 |
WO2004050683A2 (fr) * | 2002-12-02 | 2004-06-17 | Abgenix, Inc. | Anticorps agissant sur le facteur de necrose des tumeurs (tnf) et leurs utilisation |
EP2953634B1 (fr) | 2013-02-07 | 2021-05-26 | The General Hospital Corporation | Procédés d'expansion ou de déplétion de lymphocytes t régulateurs |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3723249A (en) * | 1970-02-21 | 1973-03-27 | Ajinomoto Kk | Method of producing l-arginine by microorganism |
JPS6066989A (ja) * | 1983-09-24 | 1985-04-17 | Kyowa Hakko Kogyo Co Ltd | L−アルギニンの製造法 |
EP0155549B1 (fr) * | 1984-03-06 | 1991-03-20 | Dainippon Pharmaceutical Co., Ltd. | ADN codant pour le facteur humain de nécrose de tumeur et le polypeptide du facteur humain de nécrose de tumeur |
GR851626B (fr) * | 1984-07-05 | 1985-11-26 | Genentech Inc | |
DE3581730D1 (de) * | 1984-10-15 | 1991-03-14 | Cetus Corp | Menschlicher tumornekrosisfaktor. |
EP0205038A1 (fr) * | 1985-05-29 | 1986-12-17 | Suntory Limited | Polypeptide, son procédé de préparation, micro-organisme et utilisation pharmaceutique |
-
1987
- 1987-06-16 DE DE3750056T patent/DE3750056T2/de not_active Expired - Fee Related
- 1987-06-16 AT AT87108709T patent/ATE107362T1/de not_active IP Right Cessation
- 1987-06-16 EP EP87108709A patent/EP0251037B1/fr not_active Expired - Lifetime
- 1987-06-19 HU HU872805A patent/HU210118B/hu not_active IP Right Cessation
- 1987-06-19 AU AU74508/87A patent/AU592196B2/en not_active Ceased
- 1987-06-19 SU SU874202872A patent/SU1762761A3/ru active
- 1987-06-19 DK DK312387A patent/DK312387A/da not_active Application Discontinuation
- 1987-06-20 KR KR1019870006259A patent/KR880000471A/ko not_active Application Discontinuation
- 1987-06-22 US US07/064,609 patent/US4990455A/en not_active Expired - Fee Related
- 1987-07-19 PH PH35431A patent/PH26714A/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE3750056D1 (de) | 1994-07-21 |
US4990455A (en) | 1991-02-05 |
KR880000471A (ko) | 1988-03-26 |
HUT46065A (en) | 1988-09-28 |
DK312387A (da) | 1987-12-21 |
AU7450887A (en) | 1988-01-07 |
ATE107362T1 (de) | 1994-07-15 |
DE3750056T2 (de) | 1995-04-06 |
DK312387D0 (da) | 1987-06-19 |
EP0251037A2 (fr) | 1988-01-07 |
AU592196B2 (en) | 1990-01-04 |
SU1762761A3 (ru) | 1992-09-15 |
EP0251037A3 (en) | 1988-12-07 |
EP0251037B1 (fr) | 1994-06-15 |
HU210118B (en) | 1995-02-28 |
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