PH25949A - Chewing gum containing high potency sweetener particle with modified zein coating - Google Patents
Chewing gum containing high potency sweetener particle with modified zein coating Download PDFInfo
- Publication number
- PH25949A PH25949A PH39577A PH39577A PH25949A PH 25949 A PH25949 A PH 25949A PH 39577 A PH39577 A PH 39577A PH 39577 A PH39577 A PH 39577A PH 25949 A PH25949 A PH 25949A
- Authority
- PH
- Philippines
- Prior art keywords
- zein
- percent
- weight
- sweetener
- solution
- Prior art date
Links
- 229920002494 Zein Polymers 0.000 title claims description 168
- 239000005019 zein Substances 0.000 title claims description 168
- 229940093612 zein Drugs 0.000 title claims description 168
- 235000003599 food sweetener Nutrition 0.000 title claims description 103
- 239000003765 sweetening agent Substances 0.000 title claims description 103
- 239000002245 particle Substances 0.000 title claims description 69
- 235000015218 chewing gum Nutrition 0.000 title claims description 62
- 229940112822 chewing gum Drugs 0.000 title claims description 58
- 239000011248 coating agent Substances 0.000 title claims description 29
- 238000000576 coating method Methods 0.000 title claims description 29
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 69
- 239000000203 mixture Substances 0.000 claims description 68
- 239000000243 solution Substances 0.000 claims description 67
- 238000000034 method Methods 0.000 claims description 60
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical group CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 53
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 48
- 235000010357 aspartame Nutrition 0.000 claims description 41
- 108010011485 Aspartame Proteins 0.000 claims description 40
- 239000000605 aspartame Substances 0.000 claims description 40
- 229960003438 aspartame Drugs 0.000 claims description 40
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- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 17
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- NUFKRGBSZPCGQB-FLBSXDLDSA-N (3s)-3-amino-4-oxo-4-[[(2r)-1-oxo-1-[(2,2,4,4-tetramethylthietan-3-yl)amino]propan-2-yl]amino]butanoic acid;pentahydrate Chemical compound O.O.O.O.O.OC(=O)C[C@H](N)C(=O)N[C@H](C)C(=O)NC1C(C)(C)SC1(C)C.OC(=O)C[C@H](N)C(=O)N[C@H](C)C(=O)NC1C(C)(C)SC1(C)C NUFKRGBSZPCGQB-FLBSXDLDSA-N 0.000 claims description 7
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- HCAJEUSONLESMK-UHFFFAOYSA-N cyclohexylsulfamic acid Chemical class OS(=O)(=O)NC1CCCCC1 HCAJEUSONLESMK-UHFFFAOYSA-N 0.000 claims description 3
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical class C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 claims description 3
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- 239000000463 material Substances 0.000 description 7
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- 235000020357 syrup Nutrition 0.000 description 3
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 2
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- 235000019477 peppermint oil Nutrition 0.000 description 1
- 239000008177 pharmaceutical agent Substances 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
- 239000004208 shellac Substances 0.000 description 1
- ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 description 1
- 235000013874 shellac Nutrition 0.000 description 1
- 229940113147 shellac Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 235000019721 spearmint oil Nutrition 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 229920003048 styrene butadiene rubber Polymers 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- 230000009967 tasteless effect Effects 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 229960002622 triacetin Drugs 0.000 description 1
- KJIOQYGWTQBHNH-UHFFFAOYSA-N undecanol Chemical compound CCCCCCCCCCCO KJIOQYGWTQBHNH-UHFFFAOYSA-N 0.000 description 1
- 239000008371 vanilla flavor Substances 0.000 description 1
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
- 235000012141 vanillin Nutrition 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 239000009637 wintergreen oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/10—Chewing gum characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/02—Apparatus specially adapted for manufacture or treatment of chewing gum
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/18—Chewing gum characterised by shape, structure or physical form, e.g. aerated products
- A23G4/20—Composite products, e.g. centre-filled, multi-layer, laminated
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Confectionery (AREA)
- Seasonings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/279,215 US4931295A (en) | 1988-12-02 | 1988-12-02 | Chewing gum containing high-potency sweetener particles with modified zein coating |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH25949A true PH25949A (en) | 1992-01-13 |
Family
ID=23068110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH39577A PH25949A (en) | 1988-12-02 | 1989-11-23 | Chewing gum containing high potency sweetener particle with modified zein coating |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4931295A (zh) |
| EP (1) | EP0427796B1 (zh) |
| JP (1) | JPH03503365A (zh) |
| CN (1) | CN1043071A (zh) |
| AU (1) | AU617270B2 (zh) |
| CA (1) | CA1337509C (zh) |
| DE (1) | DE68909603T2 (zh) |
| FI (1) | FI903839A0 (zh) |
| NZ (1) | NZ231383A (zh) |
| PH (1) | PH25949A (zh) |
| WO (1) | WO1990006062A1 (zh) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192563A (en) * | 1986-10-22 | 1993-03-09 | Wm. Wrigley, Jr. Company | Strongly mint-flavored chewing gums with reduced bitterness and harshness |
| US5221543A (en) * | 1986-10-22 | 1993-06-22 | Firma Wilhelm Fette Gmbh | Method of making a fast release stabilized aspartame ingredient for chewing gum |
| US5112625A (en) * | 1989-02-15 | 1992-05-12 | Wm. Wrigley Jr. Company | Aqueous zein coated sweeteners and other ingredients for chewing gum |
| US5034231A (en) * | 1989-03-28 | 1991-07-23 | Wm. Wrigly, Jr. Company | Alitame stability using hydrogenated starch hydrolysate syrups |
| US5039530A (en) * | 1990-03-01 | 1991-08-13 | Wm. Wrigley Jr. Company | Storage stable chewing gum containing alitame |
| ATE107136T1 (de) * | 1989-03-28 | 1994-07-15 | Wrigley W M Jun Co | Kaugummi mit länger anhaltender süsse mittels alitam. |
| AU617610B2 (en) * | 1989-03-28 | 1991-11-28 | Wm. Wrigley Jr. Company | Storage stable chewing gum containing alitame |
| ATE96279T1 (de) * | 1989-03-28 | 1993-11-15 | Wrigley W M Jun Co | Verbesserte alitamstabilitaet durch verwendung von hydrierter staerkehydrolysatsirupe. |
| US4997659A (en) * | 1989-03-28 | 1991-03-05 | The Wm. Wrigley Jr. Company | Alitame stability in chewing gum by encapsulation |
| JP2641620B2 (ja) * | 1989-11-09 | 1997-08-20 | アドバンスト ポリマー システムズ，インコーポレイティド | 経口導入製品に味付けする方法及び組成物 |
| US5167972A (en) * | 1990-09-04 | 1992-12-01 | Wm. Wrigley Jr. Company | Method of stabilizing peptide sweeteners in cinnamon-flavored chewing gums and confections |
| WO1990013994A2 (en) * | 1990-07-17 | 1990-11-29 | Wm. Wrigley Jr. Company | Controlled release of dihydrochalcones in chewing gum |
| US5192561A (en) * | 1991-09-19 | 1993-03-09 | Wm. Wrigley Jr. Company | Aspartame stability in chewing gum using an acid gelatin system |
| US5164210A (en) * | 1991-10-08 | 1992-11-17 | Wm. Wrigley Jr. Company | Zein/shellac encapsulation of high intensity sweeteners in chewing gum |
| US5599556A (en) * | 1991-12-31 | 1997-02-04 | Abbott Laboratories | Prolamine coatings for taste masking |
| US5334397A (en) * | 1992-07-14 | 1994-08-02 | Amurol Products Company | Bubble gum formulation |
| US5324351A (en) * | 1992-08-13 | 1994-06-28 | Euroceltique | Aqueous dispersions of zein and preparation thereof |
| WO1994014330A1 (en) * | 1992-09-01 | 1994-07-07 | Song Joo H | Flavor releasing structures modified with plasticizer for chewing gum |
| US5482722A (en) * | 1994-09-26 | 1996-01-09 | Opta Food Ingredients, Inc. | Confections comprising a proteinaceous chewable base |
| US5474787A (en) * | 1994-10-21 | 1995-12-12 | The Wm. Wrigley Jr. Company | Chewing gum containing a lecithin/glycerol triacetate blend |
| US6479082B1 (en) | 1996-12-23 | 2002-11-12 | Wm. Wrigley, Jr. Co. | Process of increasing flavor release from chewing gum using hydroxypropyl cellulose and product thereof |
| US6020008A (en) * | 1997-02-14 | 2000-02-01 | Wm. Wrigley Jr. Company | Prolamine miscible blends |
| CA2310492A1 (en) | 1997-12-03 | 1999-06-10 | Wm. Wrigley Jr. Company | Improved chewing gum formulations including aspartame and sodium bicarbonate |
| CA2478620A1 (en) | 1998-03-04 | 1999-09-10 | Dandy A/S | Coated chewing gum comprising an active substance having local activity |
| US6238711B1 (en) | 1998-11-25 | 2001-05-29 | Wm. Wrigley Jr. Company | Chewing gum with increased flavor release using an aliginate material and method of making |
| CA2366768C (en) | 1999-04-01 | 2005-05-24 | Wm. Wrigley Jr. Company | Long flavor duration releasing structures for chewing gum |
| EP1392125A1 (en) | 2001-05-15 | 2004-03-03 | The Procter & Gamble Company | Confectionery compositions |
| US20030215543A1 (en) * | 2002-05-16 | 2003-11-20 | Jingping Liu | Plasticized corn proteins and chewing gums containing same |
| US6733578B2 (en) | 2002-06-20 | 2004-05-11 | Wm. Wrigley Jr. Company | Plasticized prolamine compositions |
| US6858238B2 (en) * | 2002-06-26 | 2005-02-22 | Wm. Wrigley Jr. Company | Chewing gum products including prolamine blends |
| US20040086595A1 (en) * | 2002-10-31 | 2004-05-06 | Jingping Liu | Plasticized prolamine compositions |
| US20040101494A1 (en) * | 2002-11-26 | 2004-05-27 | Scott Douglas Craig | Chewable solid unit dosage forms and methods for delivery of active agents into occlusal surfaces of teeth |
| MX2009001764A (es) * | 2006-08-17 | 2009-02-25 | Gumlink As | Edulcorante de alta intensidad encapsulado en resina. |
| US20100189845A1 (en) * | 2009-01-27 | 2010-07-29 | Frito-Lay North America Inc. | Flavor Encapsulation and Method Thereof |
| US9504274B2 (en) * | 2009-01-27 | 2016-11-29 | Frito-Lay North America, Inc. | Methods of flavor encapsulation and matrix-assisted concentration of aqueous foods and products produced therefrom |
| CA2902911C (en) | 2014-10-31 | 2017-06-27 | Purdue Pharma | Methods and compositions particularly for treatment of attention deficit disorder |
| US10722473B2 (en) | 2018-11-19 | 2020-07-28 | Purdue Pharma L.P. | Methods and compositions particularly for treatment of attention deficit disorder |
| CN114601011A (zh) * | 2022-03-18 | 2022-06-10 | 阜阳师范大学 | 一种荆芥可降解口香糖及其制作方法 |
| CN115462493B (zh) * | 2022-09-27 | 2023-09-05 | 青岛啤酒股份有限公司 | 基于植物多肽封装掩味的复合纳米颗粒及所得饮品 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US29682A (en) * | 1860-08-21 | Feed-motion foe | ||
| CA675004A (en) * | 1963-11-26 | D. Peebles David | Sweetening product and method of manufacture | |
| US3262788A (en) * | 1963-06-25 | 1966-07-26 | Dairy Mour Inc | Process for aggregating difficult to aggregate particles and the product thereof |
| DE1792525A1 (de) * | 1968-09-13 | 1972-01-27 | Hag Ag | Verfahren zur Herstellung poroeser und koerniger Aggregate aus pulverfoermigem Material |
| GB1274905A (en) * | 1969-08-12 | 1972-05-17 | Meiji Seika Kaisha | Processes for the production of instantly soluble and/or dispersible agglomerates |
| US3753739A (en) | 1970-11-05 | 1973-08-21 | Alberto Culver Co | Low calorie dry sweetener composition |
| US3922354A (en) * | 1973-08-20 | 1975-11-25 | Norda Inc | Production of artificial spice particles |
| US3928633A (en) * | 1973-12-03 | 1975-12-23 | Gen Foods Corp | Sweetening composition and process therefor |
| US4004039A (en) * | 1973-12-03 | 1977-01-18 | General Foods Corporation | Sweetening composition and process therefor |
| US3956507A (en) * | 1973-12-03 | 1976-05-11 | General Foods Corporation | Sweetening composition and process therefor |
| US4059706A (en) * | 1974-03-07 | 1977-11-22 | General Foods Corporation | Spray-dried L-aspartic acid derivatives |
| US3962468A (en) * | 1974-03-07 | 1976-06-08 | General Foods Corporation | Spray-dried L-aspartic acid derivatives |
| US4049706A (en) * | 1975-09-24 | 1977-09-20 | Air Products And Chemicals, Inc. | Selective oxidation of chrysanthemyl alcohol |
| US4517214A (en) * | 1976-04-05 | 1985-05-14 | General Foods Corporation | Sweetening composition and method |
| US4122195A (en) * | 1977-01-24 | 1978-10-24 | General Foods Corporation | Fixation of APM in chewing gum |
| US4230687A (en) * | 1978-05-30 | 1980-10-28 | Griffith Laboratories U.S.A., Inc. | Encapsulation of active agents as microdispersions in homogeneous natural polymeric matrices |
| JPS588818B2 (ja) * | 1979-09-21 | 1983-02-17 | 株式会社 ロツテ | 発泡性チユ−インガムの製造方法 |
| US4384005A (en) * | 1980-09-26 | 1983-05-17 | General Foods Corporation | Non-friable, readily-soluble, compressed tablets and process for preparing same |
| US4384004A (en) * | 1981-06-02 | 1983-05-17 | Warner-Lambert Company | Encapsulated APM and method of preparation |
| JPS58157509A (ja) * | 1982-03-10 | 1983-09-19 | Hitachi Ltd | 圧延機及び圧延方法 |
| EP0101756A1 (de) * | 1982-08-31 | 1984-03-07 | Chimicasa Gmbh | Wasserlösliche Süssungstablette |
| JPS5995862A (ja) * | 1982-11-25 | 1984-06-02 | Ajinomoto Co Inc | ジペプチド甘味料顆粒の製造法 |
| US4497835A (en) * | 1983-01-10 | 1985-02-05 | Alberta Gas Chemicals, Incorporated | Artificially sweetened beverage mixes and process therefor |
| US4673577A (en) * | 1983-02-18 | 1987-06-16 | Wm. Wrigley Jr. Company | Shellac encapsulant for high-potency sweeteners in chewing gum |
| JPH0631312B2 (ja) * | 1983-03-18 | 1994-04-27 | 味の素株式会社 | ジペプチド結晶及びその製造方法 |
| US4556565A (en) * | 1983-11-04 | 1985-12-03 | Tetsuo Arima | Sweetener composition, process for making the same, and comestibles comprising said sweetener composition |
| US4568560A (en) * | 1984-03-16 | 1986-02-04 | Warner-Lambert Company | Encapsulated fragrances and flavors and process therefor |
| US4554167A (en) * | 1984-06-14 | 1985-11-19 | General Foods Corp. | Method for agglomerating aspartame and acid-containing mixes |
| US4597970A (en) * | 1984-10-05 | 1986-07-01 | Warner-Lambert Company | Chewing gum compositions containing novel sweetener delivery systems and method of preparation |
| US4741910A (en) * | 1984-12-14 | 1988-05-03 | Nabisco Brands, Inc. | Method for making agglomerated bits containing aspartame |
| US4634593A (en) * | 1985-07-31 | 1987-01-06 | Nabisco Brands, Inc. | Composition and method for providing controlled release of sweetener in confections |
| US4711784A (en) * | 1986-01-07 | 1987-12-08 | Warner-Lambert Company | Encapsulation composition for use with chewing gum and edible products |
| PT84102B (pt) * | 1986-01-16 | 1989-07-31 | Dow Chemical Co | Processo para a preparacao de composicoes edulcorantes artificiais em particulas, termicamente estaveis, contendo um edulcorante oligopeptidico |
| DE3776348D1 (de) * | 1987-12-15 | 1992-03-05 | Wrigley W M Jun Co | Verfahren zur herstellung von produkten mit kontrollierter freigabe fuer kaugummi. |
| WO1989003170A2 (en) * | 1988-12-09 | 1989-04-20 | Wm. Wrigley Jr. Company | Method of controlling release of acesulfame k in chewing gum and gum produced thereby |
-
1988
- 1988-12-02 US US07/279,215 patent/US4931295A/en not_active Expired - Lifetime
-
1989
- 1989-09-22 CA CA000612453A patent/CA1337509C/en not_active Expired - Lifetime
- 1989-11-14 NZ NZ231383A patent/NZ231383A/en unknown
- 1989-11-17 AU AU47507/90A patent/AU617270B2/en not_active Ceased
- 1989-11-17 WO PCT/US1989/005159 patent/WO1990006062A1/en active IP Right Grant
- 1989-11-17 DE DE90900603T patent/DE68909603T2/de not_active Expired - Fee Related
- 1989-11-17 EP EP90900603A patent/EP0427796B1/en not_active Expired - Lifetime
- 1989-11-17 JP JP2500873A patent/JPH03503365A/ja active Pending
- 1989-11-23 PH PH39577A patent/PH25949A/en unknown
- 1989-11-24 CN CN89108855A patent/CN1043071A/zh active Pending
-
1990
- 1990-08-01 FI FI903839A patent/FI903839A0/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU4750790A (en) | 1990-06-26 |
| FI903839A0 (fi) | 1990-08-01 |
| JPH03503365A (ja) | 1991-08-01 |
| DE68909603D1 (de) | 1993-11-04 |
| EP0427796A4 (en) | 1991-06-05 |
| AU617270B2 (en) | 1991-11-21 |
| EP0427796B1 (en) | 1993-09-29 |
| WO1990006062A1 (en) | 1990-06-14 |
| CA1337509C (en) | 1995-11-07 |
| NZ231383A (en) | 1991-06-25 |
| US4931295A (en) | 1990-06-05 |
| DE68909603T2 (de) | 1994-05-11 |
| CN1043071A (zh) | 1990-06-20 |
| EP0427796A1 (en) | 1991-05-22 |
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