PH25618A - Stabilised human protein preparation - Google Patents
Stabilised human protein preparationInfo
- Publication number
- PH25618A PH25618A PH37498A PH37498A PH25618A PH 25618 A PH25618 A PH 25618A PH 37498 A PH37498 A PH 37498A PH 37498 A PH37498 A PH 37498A PH 25618 A PH25618 A PH 25618A
- Authority
- PH
- Philippines
- Prior art keywords
- human protein
- protein preparation
- stabilised
- agents
- stabilised human
- Prior art date
Links
- 102000003839 Human Proteins Human genes 0.000 title abstract 2
- 108090000144 Human Proteins Proteins 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000002347 injection Methods 0.000 abstract 2
- 239000007924 injection Substances 0.000 abstract 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract 1
- 102000003951 Erythropoietin Human genes 0.000 abstract 1
- 108090000394 Erythropoietin Proteins 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000000872 buffer Substances 0.000 abstract 1
- 239000001110 calcium chloride Substances 0.000 abstract 1
- 229910001628 calcium chloride Inorganic materials 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000008139 complexing agent Substances 0.000 abstract 1
- 229940105423 erythropoietin Drugs 0.000 abstract 1
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Marine Sciences & Fisheries (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873729863 DE3729863A1 (de) | 1987-09-05 | 1987-09-05 | Stabilisierte erythropoietin-lyophilisate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH25618A true PH25618A (en) | 1991-08-08 |
Family
ID=6335375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH37498A PH25618A (en) | 1987-09-05 | 1988-09-02 | Stabilised human protein preparation |
Country Status (29)
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5981485A (en) | 1997-07-14 | 1999-11-09 | Genentech, Inc. | Human growth hormone aqueous formulation |
| NZ232813A (en) * | 1989-03-10 | 1992-08-26 | Snow Brand Milk Products Co Ltd | Human fibroblast glycoprotein, cell differentiation, blood vessel endothelial cell growth factor, cellular immunology inforcing factor of 78 or 74 thousand daltons plus or minus two thousand daltons |
| JPH0341033A (ja) * | 1989-07-07 | 1991-02-21 | Kyowa Hakko Kogyo Co Ltd | 安定なモチリン類含有製剤 |
| DE3939346A1 (de) * | 1989-11-29 | 1991-06-06 | Behringwerke Ag | Arzneimitel zur subkutanen oder intramuskulaeren applikation enthaltend polypeptide |
| DE4014654A1 (de) * | 1990-05-08 | 1991-11-14 | Behringwerke Ag | Galenische waessrige formulierungen von erythropoietin und ihre verwendung |
| DE4126983A1 (de) * | 1991-08-15 | 1993-02-18 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von humanprotein-enthaltenden, konservierten arzneimitteln fuer infusions- oder injektionszwecke |
| DE4126984A1 (de) * | 1991-08-15 | 1993-02-18 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von humanprotein-enthaltenden, gut vertraeglichen arzneimitteln fuer infusions- oder injektionszwecke |
| US5912015A (en) * | 1992-03-12 | 1999-06-15 | Alkermes Controlled Therapeutics, Inc. | Modulated release from biocompatible polymers |
| US5716644A (en) * | 1992-06-11 | 1998-02-10 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US20030035845A1 (en) * | 1992-06-11 | 2003-02-20 | Zale Stephen E. | Composition for sustained release of non-aggregated erythropoietin |
| US5674534A (en) * | 1992-06-11 | 1997-10-07 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5661125A (en) * | 1992-08-06 | 1997-08-26 | Amgen, Inc. | Stable and preserved erythropoietin compositions |
| EP0582933A1 (de) * | 1992-08-11 | 1994-02-16 | F. Hoffmann-La Roche Ag | Therapeutisches System zur parenteralen Verabreichung von hämatopoetischen Wachstumsfaktoren |
| DE4242919A1 (de) * | 1992-12-18 | 1994-06-23 | Boehringer Mannheim Gmbh | Verfahren zur Herstellung von lagerstabilen wässrigen pharmazeutischen Zubereitungen von G-CSF |
| US5358708A (en) * | 1993-01-29 | 1994-10-25 | Schering Corporation | Stabilization of protein formulations |
| US6372716B1 (en) * | 1994-04-26 | 2002-04-16 | Genetics Institute, Inc. | Formulations for factor IX |
| FR2719479B1 (fr) * | 1994-05-04 | 1996-07-26 | Sanofi Elf | Formulation stable lyophilisée comprenant une protéine: kit de dosage. |
| JP2747979B2 (ja) * | 1994-08-19 | 1998-05-06 | 雪印乳業株式会社 | ヒト由来の糖蛋白質からなる生理活性因子を有効成分とする医薬 |
| IL116085A (en) * | 1994-12-16 | 1999-12-31 | Ortho Pharma Corp | Spray dried erythropoietin |
| ZA966075B (en) * | 1995-07-27 | 1998-01-19 | Genentech Inc | Protein formulation. |
| JP2000507912A (ja) * | 1995-08-31 | 2000-06-27 | アルカームズ コントロールド セラピューティックス，インコーポレイテッド | 作用剤の徐放性組成物 |
| DE19539574A1 (de) * | 1995-10-25 | 1997-04-30 | Boehringer Mannheim Gmbh | Zubereitungen und Verfahren zur Stabilisierung biologischer Materialien mittels Trocknungsverfahren ohne Einfrieren |
| US20030138402A1 (en) * | 1995-12-25 | 2003-07-24 | Otsuka Pharmaceutical Co., Ltd. | Dry compositions |
| US5770700A (en) * | 1996-01-25 | 1998-06-23 | Genetics Institute, Inc. | Liquid factor IX formulations |
| TWI240627B (en) * | 1996-04-26 | 2005-10-01 | Chugai Pharmaceutical Co Ltd | Erythropoietin solution preparation |
| US20030190307A1 (en) * | 1996-12-24 | 2003-10-09 | Biogen, Inc. | Stable liquid interferon formulations |
| WO1998028007A1 (en) * | 1996-12-24 | 1998-07-02 | Biogen, Inc. | Stable liquid interferon formulations |
| DE19716154A1 (de) * | 1997-04-18 | 1998-10-22 | Boehringer Mannheim Gmbh | Stabile pharmazeutische Darreichungsform für Peptide, Proteine und Nukleinsäuren |
| RU2152206C1 (ru) * | 1997-05-22 | 2000-07-10 | Государственный научный центр вирусологии и биотехнологии "Вектор" | Таблетированная форма рекомбинантного человеческого эритропоэтина для перорального применения и способ ее получения |
| KR100641969B1 (ko) * | 1997-07-23 | 2006-11-06 | 로셰 디아그노스틱스 게엠베하 | 내인성 유전자 활성화에 의한 에리트로포이에틴의제조방법 |
| US6548296B1 (en) * | 1997-07-23 | 2003-04-15 | Roche Diagnostics Gmbh | Methods for identifying human cell lines useful for endogenous gene activation, isolated human lines identified thereby, and uses thereof |
| EP0965349A1 (de) * | 1998-06-18 | 1999-12-22 | Roche Diagnostics GmbH | Verwendung von Erythropoietin zur Behandlung von Hämochromatosen |
| AR019025A1 (es) | 1998-04-09 | 2001-12-26 | Roche Diagnostics Gmbh | Uso de eritropoyetina en bajas dosis para producir un preparado farmaceutico para el tratamiento de hemocromatosis, preparado farmaceutico combinadoutilizado segun dicho uso y envase farmaceutico unitario que contiene al referido preparado farmaceutico combinado |
| RU2128517C1 (ru) * | 1998-07-20 | 1999-04-10 | Колобков Сергей Леонидович | Стабилизированный водный раствор эритропоэтина |
| JP2000247903A (ja) * | 1999-03-01 | 2000-09-12 | Chugai Pharmaceut Co Ltd | 長期安定化製剤 |
| RU2225221C2 (ru) * | 1999-04-09 | 2004-03-10 | Орто-Макнейл Фармасьютикал, Инк. | ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ Эритропоэтина |
| US7345019B1 (en) * | 1999-04-13 | 2008-03-18 | The Kenneth S. Warren Institute, Inc. | Modulation of excitable tissue function by peripherally administered erythropoietin |
| WO2001017542A1 (fr) * | 1999-09-08 | 2001-03-15 | Chugai Seiyaku Kabushiki Kaisha | Preparation de solution de proteines et procede de stabilisation associe |
| RU2182141C2 (ru) * | 2000-03-20 | 2002-05-10 | Братский государственный технический университет | Композиция для изготовления легкобетонных изделий |
| CN1309416C (zh) * | 2000-05-15 | 2007-04-11 | 霍夫曼-拉罗奇有限公司 | 新的药物组合物 |
| AU2005225151B2 (en) * | 2000-05-15 | 2008-05-29 | F. Hoffmann-La Roche Ag | New pharmaceutical composition |
| DK1314437T3 (da) * | 2000-08-11 | 2014-07-14 | Chugai Pharmaceutical Co Ltd | Stabiliserede antistofindeholdende præparater |
| US7767643B2 (en) | 2000-12-29 | 2010-08-03 | The Kenneth S. Warren Institute, Inc. | Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs |
| US20030072737A1 (en) * | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
| RU2191594C1 (ru) * | 2001-04-03 | 2002-10-27 | Григорян Седа Суреновна | Средство и способ повышения резистентности к инфекции |
| RU2192882C1 (ru) * | 2001-04-18 | 2002-11-20 | Эпштейн Олег Ильич | Лекарственное средство и способ лечения патологического синдрома, обусловленного нарушением кроветворения |
| EG24184A (en) * | 2001-06-15 | 2008-10-08 | Otsuka Pharma Co Ltd | Dry powder inhalation system for transpulmonary |
| DE10149030A1 (de) | 2001-10-05 | 2003-04-10 | Viscum Ag | Stabile galenische gefriergetrocknete Arzneimittelzubereitung von rViscumin |
| US7132100B2 (en) | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
| US7425618B2 (en) * | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
| SI21257A (sl) * | 2002-07-17 | 2004-02-29 | LEK farmacevtska dru�ba d.d. | Stabilni farmacevtski pripravek, ki vsebuje eritropoietin |
| DE10234192B4 (de) * | 2002-07-26 | 2009-11-26 | Epoplus Gmbh Co.Kg | Verwendung von Erythropoetin |
| US20040208869A1 (en) * | 2003-01-30 | 2004-10-21 | Medimmune, Inc. | Uses of anti-integrin alphanubeta3 antibody formulations |
| ES2385888T3 (es) | 2003-06-10 | 2012-08-02 | Lg Life Sciences Ltd. | Solución acuosa estable de eritropoyetina humana que no contiene albúmina sérica |
| FR2857267B1 (fr) * | 2003-07-09 | 2006-03-10 | Lab Francais Du Fractionnement | Formulation stabilisante et solubilisante pour les proteines cryoprecipitables. |
| KR100560697B1 (ko) * | 2003-08-06 | 2006-03-16 | 씨제이 주식회사 | 알부민을 함유하지 않는 에리스로포이에틴 제제 |
| BRPI0414887A (pt) * | 2003-09-29 | 2006-12-12 | Warren Pharmaceuticals Inc E T | métodos de tratamento, prevenção, retardo do inìcio ou redução dos efeitos de citocinas pró-inflamatórias em um mamìfero e de tratamento, prevenção, retardo do inìcio de uma condição associada com um efeito de citocinas pró-inflamatórias em um mamìfero, e, composição farmacêutica |
| US7141544B2 (en) * | 2003-10-10 | 2006-11-28 | Baxter International, Inc. | Stabilization of pharmaceutical protein formulations with small peptides |
| EP1537876A1 (en) * | 2003-12-01 | 2005-06-08 | BioGeneriX AG | Erythropoietin solution formulation |
| DE102004011663B4 (de) * | 2004-03-10 | 2006-04-27 | Bioceuticals Arzneimittel Ag | Erythropoietin-Flüssigformulierung |
| US7772182B2 (en) * | 2004-08-05 | 2010-08-10 | Alza Corporation | Stable suspension formulations of erythropoietin receptor agonists |
| DE102005033250A1 (de) | 2005-07-15 | 2007-01-18 | Bioceuticals Arzneimittel Ag | Verfahren zur Reinigung von G-CSF |
| RS60101B1 (sr) * | 2008-08-15 | 2020-05-29 | Ironwood Pharmaceuticals Inc | Formulacije koje sadrže linaklotid za oralnu primenu |
| MX2012001660A (es) * | 2009-08-06 | 2012-03-26 | Ironwood Pharmaceuticals Inc | Formulaciones que contienen linaclotida para adminstracion oral. |
| DK2521561T3 (en) * | 2009-11-03 | 2017-09-11 | Ironwood Pharmaceuticals Inc | LINACLOTID FOR TREATMENT OF CHRONIC CONSTIPATION |
| TWI417104B (zh) | 2010-01-19 | 2013-12-01 | Hanmi Science Co Ltd | 用於長效型紅血球生成素共軛物之液態劑型 |
| CN102869677B (zh) | 2010-02-17 | 2015-07-08 | 硬木药品公司 | 胃肠病症的治疗 |
| US20140005128A1 (en) | 2010-08-11 | 2014-01-02 | Forest Laboratories Holdings Limited | Treatments of gastrointestinal disorders |
| HUE032237T2 (en) | 2011-08-17 | 2017-09-28 | Ironwood Pharmaceuticals Inc | Treatments for gastrointestinal disorders |
| EA022327B1 (ru) * | 2013-01-04 | 2015-12-30 | Общество С Ограниченной Ответственностью "Рубикон" | Инъекционное ветеринарное средство в форме раствора для борьбы с полиинвазиями животного и способ его получения |
| EP3125922B1 (en) | 2014-03-29 | 2020-10-14 | Intas Pharmaceuticals Limited | Liquid pharmaceutical composition of conjugated erythropoietin |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3865801A (en) * | 1973-06-15 | 1975-02-11 | Atomic Energy Commission | Stabilization of urinary erythropoietin using sodium p-aminosalicylate and extracting into phenol |
| JPS6197229A (ja) * | 1984-10-18 | 1986-05-15 | Chugai Pharmaceut Co Ltd | 安定なエリトロポエチン製剤 |
| WO1986005096A1 (en) * | 1985-03-06 | 1986-09-12 | Survival Technology, Inc. | Protein absorption enhancing agents |
-
1987
- 1987-09-05 DE DE19873729863 patent/DE3729863A1/de not_active Withdrawn
-
1988
- 1988-08-30 DK DK198804831A patent/DK174811B1/da active
- 1988-08-30 NZ NZ225975A patent/NZ225975A/en unknown
- 1988-08-30 DD DD88319317A patent/DD273004A5/de unknown
- 1988-08-31 MX MX1288088A patent/MX12880A/es unknown
- 1988-08-31 IL IL87628A patent/IL87628A/xx not_active IP Right Cessation
- 1988-09-01 PL PL1988274485A patent/PL157944B1/pl unknown
- 1988-09-01 DE DE8888114246T patent/DE3872334D1/de not_active Expired - Lifetime
- 1988-09-01 ES ES88114246T patent/ES2051806T3/es not_active Expired - Lifetime
- 1988-09-01 CS CS590188A patent/CS274681B2/cs not_active IP Right Cessation
- 1988-09-01 US US07/240,005 patent/US4992419A/en not_active Expired - Lifetime
- 1988-09-01 AT AT88114246T patent/ATE77556T1/de not_active IP Right Cessation
- 1988-09-01 EP EP88114246A patent/EP0306824B1/de not_active Expired - Lifetime
- 1988-09-02 ZA ZA886528A patent/ZA886528B/xx unknown
- 1988-09-02 PH PH37498A patent/PH25618A/en unknown
- 1988-09-02 IE IE267188A patent/IE60310B1/en not_active IP Right Cessation
- 1988-09-02 HU HU884536A patent/HU202761B/hu unknown
- 1988-09-02 NO NO883926A patent/NO178687C/no not_active IP Right Cessation
- 1988-09-02 AU AU21739/88A patent/AU610636B2/en not_active Expired
- 1988-09-02 CA CA000577075A patent/CA1330301C/en not_active Expired - Lifetime
- 1988-09-02 FI FI884051A patent/FI93517C/fi not_active IP Right Cessation
- 1988-09-02 PT PT88417A patent/PT88417B/pt not_active IP Right Cessation
- 1988-09-05 KR KR1019880011488A patent/KR960009929B1/ko not_active Expired - Lifetime
- 1988-09-05 UA UA5010234A patent/UA26855C2/uk unknown
- 1988-09-05 UA UA4356379A patent/UA26123A/uk unknown
- 1988-09-05 JP JP63220591A patent/JPH0780782B2/ja not_active Expired - Lifetime
- 1988-09-05 CN CN88106464A patent/CN1027224C/zh not_active Expired - Lifetime
- 1988-09-05 RU SU884356379A patent/RU2043118C1/ru active
-
1991
- 1991-12-02 RU SU915010234A patent/RU2100032C1/ru active
-
1992
- 1992-08-20 GR GR920401275T patent/GR3005454T3/el unknown
-
1993
- 1993-06-02 LV LVP-93-470A patent/LV10178B/lv unknown
-
1995
- 1995-06-08 HK HK89495A patent/HK89495A/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH25618A (en) | Stabilised human protein preparation | |
| CA2203033A1 (en) | Compounds and compositions for delivering active agents | |
| ATE493998T1 (de) | Pharmazeutische zusammensetzung mit einem exendin-4-peptid | |
| GR3018009T3 (en) | Use of gamma-hydroxybutyric acid salts for preparing pharmaceutical compositions for use in the treatment of alcoholism, and the compositions obtained. | |
| EP0283713A3 (en) | Complexes of saponins with phospholipids and pharmaceutical and cosmetic compositions containing them | |
| CA2122717A1 (en) | Hemoglobins as drug delivery agents | |
| IL131381A0 (en) | Therapeutic agent for lymphatic tumors | |
| ZA881067B (en) | Production of proteins in active forms | |
| TR199903192T2 (xx) | Eritropoetin, de�i�tirilmi� hemoglobin i�eren farmasotik kombine m�stahzarlar. | |
| SG89264A1 (en) | Peritoneal dialysis solution | |
| EP0273800A3 (en) | Hirudine variants, their use and preparation | |
| PT88539A (pt) | Stabilisierung von therapeutisch wirksamen proteinen in pharmazeutischen zubereitungen | |
| DE3473826D1 (en) | N,n-diethyl-5-methyl-2h-1-benzothiopyrano-(4,3,2-cd)-indazole-2-ethanamine, compositions comprising the same and uses therefor | |
| IL94218A0 (en) | Peptides including a disulfide bond,their use in diagnosis and vaccine compositions containing them | |
| IT1242026B (it) | Composizione farmaceutica contenente un complesso ferro-schizokinene per il trattamento dell'anemia ferropenica. |