PH24498A - Tetrahydropyridazin-3-ones - Google Patents

Tetrahydropyridazin-3-ones

Info

Publication number
PH24498A
PH24498A PH36276A PH36276A PH24498A PH 24498 A PH24498 A PH 24498A PH 36276 A PH36276 A PH 36276A PH 36276 A PH36276 A PH 36276A PH 24498 A PH24498 A PH 24498A
Authority
PH
Philippines
Prior art keywords
tetrahydropyridazin
ones
Prior art date
Application number
PH36276A
Other languages
English (en)
Inventor
Donald W Combs
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/944,316 external-priority patent/US4721784A/en
Priority claimed from US07/064,638 external-priority patent/US4766118A/en
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Priority to PH38879A priority Critical patent/PH26651A/en
Publication of PH24498A publication Critical patent/PH24498A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/361,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/101,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/141,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/161,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH36276A 1986-12-22 1987-12-21 Tetrahydropyridazin-3-ones PH24498A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PH38879A PH26651A (en) 1986-12-22 1989-06-28 Benxoxazinyl and benzothiazinyl carboxylic acid

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/944,316 US4721784A (en) 1986-12-22 1986-12-22 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones
US07/064,638 US4766118A (en) 1986-12-22 1987-06-22 6-benzoxazinyl- and 6-benzothiazinyl-2,3,4,5-tetrahydropyridazin-3-ones and pharmaceutical use
US12514287A 1987-12-02 1987-12-02

Publications (1)

Publication Number Publication Date
PH24498A true PH24498A (en) 1990-07-18

Family

ID=27370654

Family Applications (1)

Application Number Title Priority Date Filing Date
PH36276A PH24498A (en) 1986-12-22 1987-12-21 Tetrahydropyridazin-3-ones

Country Status (12)

Country Link
EP (1) EP0272914A3 (de)
KR (1) KR880007527A (de)
AU (2) AU607731B2 (de)
DK (1) DK673087A (de)
FI (1) FI86425C (de)
HU (1) HU207314B (de)
IL (1) IL84832A (de)
MY (2) MY106781A (de)
NO (1) NO173653C (de)
NZ (1) NZ222843A (de)
PH (1) PH24498A (de)
PT (1) PT86453B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3934436A1 (de) * 1989-06-01 1991-04-18 Thomae Gmbh Dr K 2-hydroxy-n-propylamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
TW224941B (de) * 1989-11-08 1994-06-11 Yamanouchi Pharma Co Ltd
US5221742A (en) * 1990-12-21 1993-06-22 Ortho Pharmaceutical Corporation Process for the preparation of 6-(3,4-dihydro-3-oxo-1,4(2h)-benzoxazin-7-yl)-2,3,4,5-tetrahydropyridazin-3-ones
AU1493092A (en) * 1991-04-18 1992-10-22 Ortho Pharmaceutical Corporation (+) and (-) enantiomers of 5-aliphatic-6-(benzoxazinyl- or benzothiazinyl)-2,3,4,5-tetrahydropyridazin-3-ones
SK34398A3 (en) * 1995-09-22 1998-11-04 Sumitomo Chemical Co Pyrazin-2-one derivative, method for inhibiting undesirable weeds and use of derivatives
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
EP2522670A1 (de) 2004-04-07 2012-11-14 Takeda Pharmaceutical Company Limited Heterozyklische CRF-Rezeptor-Antagonisten
US7741317B2 (en) * 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
CN101355876B (zh) 2005-11-09 2012-09-05 康宾纳特克斯公司 一种适用于眼部给药的组合物
AU2008261102B2 (en) 2007-06-04 2013-11-28 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2930674A1 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN108676076A (zh) 2011-03-01 2018-10-19 辛纳吉制药公司 制备鸟苷酸环化酶c激动剂的方法
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
EP3718557A3 (de) 2013-02-25 2020-10-21 Bausch Health Ireland Limited Guanylat-cyclase-rezeptoragonist sp-333 zur verwendung in der darmreinigung
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
JP6606491B2 (ja) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼcの超高純度アゴニスト、その作成および使用方法
NZ717739A (en) 2013-08-09 2023-12-22 Ardelyx Inc Compounds and methods for inhibiting phosphate transport
US20200368223A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Methods for inhibiting phosphate transport

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2035749A1 (de) * 1969-02-06 1970-12-24 Bellon Labor Sa Roger
FR2588868B1 (fr) * 1985-10-21 1988-11-10 Negma Laboratoires Acyl-7 benzoxazinones et leurs derives, procede pour les obtenir et compositions pharmaceutiques les contenant
TW224941B (de) * 1989-11-08 1994-06-11 Yamanouchi Pharma Co Ltd

Also Published As

Publication number Publication date
DK673087A (da) 1988-06-23
HUT48624A (en) 1989-06-28
NO875358L (no) 1988-06-23
MY106781A (en) 1995-07-31
DK673087D0 (da) 1987-12-21
AU633666B2 (en) 1993-02-04
HU207314B (en) 1993-03-29
AU6808690A (en) 1991-04-26
NO875358D0 (no) 1987-12-21
FI875619A (fi) 1988-06-23
NZ222843A (en) 1989-10-27
NO173653C (no) 1994-01-12
KR880007527A (ko) 1988-08-27
AU8293287A (en) 1988-06-23
PT86453B (pt) 1990-11-20
IL84832A0 (en) 1988-06-30
EP0272914A3 (de) 1990-04-04
FI875619A0 (fi) 1987-12-21
NO173653B (no) 1993-10-04
IL84832A (en) 1993-01-14
PT86453A (en) 1988-01-01
FI86425B (fi) 1992-05-15
EP0272914A2 (de) 1988-06-29
FI86425C (fi) 1992-08-25
MY102280A (en) 1992-05-15
AU607731B2 (en) 1991-03-14

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